Clinical Trials

NCT05017025 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
32 participants

Aurora Kinase Inhibitor LY3295668 in Combination With Osimertinib for the Treatment of Advanced or Metastatic EGFR-Mutant Non-squamous Non-small Cell Lung Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-20
Start Date:
2022-02-17
Completion:
2026-06-30
Conditions
  • Advanced Lung Non-Squamous Non-Small Cell Carcinoma
  • Metastatic Lung Non-Squamous Non-Small Cell Carcinoma
  • Stage III Lung Cancer AJCC v8
  • Stage IIIA Lung Cancer AJCC v8
  • Stage IIIB Lung Cancer AJCC v8
  • Stage IIIC Lung Cancer AJCC v8
  • Stage IV Lung Cancer AJCC v8
  • Stage IVA Lung Cancer AJCC v8
  • Stage IVB Lung Cancer AJCC v8
Interventions
  • DRUG
No Results Yet
NCT04994717 | ACTIVE_NOT_RECRUITING | PHASE3
303 participants

Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-20
Start Date:
2021-11-02
Completion:
2029-09-07
Conditions
  • Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
Interventions
  • DRUG
No Results Yet
NCT04915612 | COMPLETED | PHASE1
1 participants

Liposomal Cytarabine, Daunorubicin, and Gemtuzumab Ozogamicin for the Treatment of Relapsed Refractory Pediatric Patients With Acute Myeloid Leukemia

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-20
Start Date:
2021-05-21
Completion:
2025-01-30
Conditions
  • Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
  • Recurrent Acute Myeloid Leukemia
  • Refractory Acute Myeloid Leukemia
  • Secondary Acute Myeloid Leukemia
Interventions
  • DRUG
No Results Yet
NCT04899687 | RECRUITING | PHASE2
60 participants

Study of Dextromethorphan in OCD and Related Disorders

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-20
Start Date:
2022-01-20
Completion:
2027-04-01
Conditions
  • Obsessive-Compulsive Disorder
  • Illness Anxiety Disorder
  • Body Dysmorphic Disorders
  • Somatic Symptom Disorder
Interventions
  • DRUG
No Results Yet
NCT04875728 | ACTIVE_NOT_RECRUITING | PHASE1
20 participants

The Impact of an Antibiotic (Cefazolin) Before Surgery on the Microbiome in Patients With Stage I-II Melanoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-20
Start Date:
2020-09-08
Completion:
2027-02-02
Conditions
  • Clinical Stage I Cutaneous Melanoma AJCC v8
  • Clinical Stage IA Cutaneous Melanoma AJCC v8
  • Clinical Stage IB Cutaneous Melanoma AJCC v8
  • Clinical Stage II Cutaneous Melanoma AJCC v8
  • Clinical Stage IIA Cutaneous Melanoma AJCC v8
  • Clinical Stage IIB Cutaneous Melanoma AJCC v8
  • Clinical Stage IIC Cutaneous Melanoma AJCC v8
  • Pathologic Stage I Cutaneous Melanoma AJCC v8
  • Pathologic Stage IA Cutaneous Melanoma AJCC v8
  • Pathologic Stage IB Cutaneous Melanoma AJCC v8
  • Pathologic Stage II Cutaneous Melanoma AJCC v8
  • Pathologic Stage IIA Cutaneous Melanoma AJCC v8
  • Pathologic Stage IIB Cutaneous Melanoma AJCC v8
  • Pathologic Stage IIC Cutaneous Melanoma AJCC v8
Interventions
  • DRUG
  • PROCEDURE
No Results Yet
NCT04816006 | RECRUITING | NA
160 participants

Breast Cancer, Reasoning, and Activity Intervention

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-20
Start Date:
2024-02-22
Completion:
2027-07-31
Conditions
  • Breast Cancer
  • Breast Neoplasms
  • Anatomic Stage I Breast Cancer AJCC v8
  • Anatomic Stage II Breast Cancer AJCC v8
  • Anatomic Stage IIIA Breast Cancer AJCC v8
  • Cancer-related Cognitive Dysfunction
Interventions
  • BEHAVIORAL
  • OTHER
No Results Yet
NCT04759911 | ACTIVE_NOT_RECRUITING | PHASE2
30 participants

Selpercatinib Before Surgery for the Treatment of RET-Altered Thyroid Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-05-20
Start Date:
2021-02-26
Completion:
2027-11-30
Conditions
  • Malignant Thyroid Gland Neoplasm
  • Poorly Differentiated Thyroid Gland Carcinoma
  • Recurrent Thyroid Gland Carcinoma
  • Thyroid Gland Anaplastic Carcinoma
  • Thyroid Gland Medullary Carcinoma
  • Thyroid Gland Papillary Carcinoma
  • Thyroid Gland Squamous Cell Carcinoma
Interventions
  • OTHER
  • DRUG
  • PROCEDURE
No Results Yet
NCT04751396 | RECRUITING
125 participants

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

Study Type:
OBSERVATIONAL
Last Updated:
2026-05-20
Start Date:
2022-04-20
Completion:
2027-02-02
Conditions
  • Ankylosing Spondylitis
  • Autoimmune Disease
  • Crohn Disease
  • Enteropathic Arthritis
  • Enteropathic Spondylitis
  • Inflammatory Bowel Disease
  • Melanoma
  • Psoriasis
  • Psoriatic Arthritis
  • Reactive Arthritis
  • Rheumatoid Arthritis
  • Systemic Lupus Erythematosus
  • Ulcerative Colitis
Interventions
  • OTHER
No Results Yet
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