Clinical Trials

NCT05288842 | RECRUITING

102 participants

Tanycytes in Alzheimer's Disease and Frontotemporal Dementia

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2022-09-06

Completion:

2026-10-31

Conditions

• Alzheimer Disease
• Frontotemporal Dementia

Interventions

• BIOLOGICAL

No Results Yet

NCT05279040 | RECRUITING

20 participants

Trikafta Exercise Study in Cystic Fibrosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2021-11-10

Completion:

2027-01-31

Conditions

• Cystic Fibrosis
• Lung Diseases

Interventions

• DRUG

No Results Yet

NCT05270668 | ACTIVE_NOT_RECRUITING | PHASE2

154 participants

Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Systemic Sclerosis Associated With Interstitial Lung Disease (SSc-ILD) (MK-7240-007)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-03-29

Completion:

2026-04-16

Conditions

• Diffuse Cutaneous Systemic Sclerosis
• Interstitial Lung Disease

Interventions

• DRUG
• DIAGNOSTIC_TEST

No Results Yet

NCT05267626 | RECRUITING | PHASE1/PHASE2

159 participants

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-04-04

Completion:

2026-06-12

Conditions

• Advanced Solid Tumor
• Metastatic Cancer
• Cutaneous Melanoma
• Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05254067 | COMPLETED

10 participants

Enterprise 2 Vascular Reconstruction Device

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2017-02-28

Completion:

2026-01-05

Conditions

• Aneurysm

Interventions

• DEVICE

No Results Yet

NCT05232032 | RECRUITING | PHASE2

112 participants

Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2025-02-01

Completion:

2027-03-31

Conditions

• Depressive Disorder, Major
• Anxiety Disorder

Interventions

• DRUG
• DEVICE

No Results Yet

NCT05228275 | ACTIVE_NOT_RECRUITING

549 participants

Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2022-04-08

Completion:

2027-09-30

Conditions

• COVID-19 Infection
• Hematopoietic and Lymphatic System Neoplasm
• Malignant Solid Neoplasm

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT05224414 | RECRUITING | NA

106 participants

Interpretation Bias as a Mechanism of Treatment Response in OCD

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-03-30

Completion:

2026-08-31

Conditions

• Obsessive-Compulsive Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05221840 | ACTIVE_NOT_RECRUITING | PHASE3

1051 participants

A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-02-07

Completion:

2026-06-30

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG
• OTHER

No Results Yet

NCT05219110 | RECRUITING | NA

1040 participants

Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-09-29

Completion:

2027-08-31

Conditions

• Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection
• Hemolytic-Uremic Syndrome

Interventions

• OTHER

No Results Yet

NCT05211895 | RECRUITING | PHASE3

860 participants

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-02-18

Completion:

2028-07-12

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG
• OTHER

No Results Yet

NCT05191277 | COMPLETED | NA

56 participants

Disentangling Pharmacological and Expectation Effects in Antidepressant Discontinuation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-08-01

Completion:

2025-02-26

Conditions

• Depressive Symptoms
• Expectations
• Antidepressants

Interventions

• DRUG
• BEHAVIORAL

No Results Yet

NCT05173064 | NOT_YET_RECRUITING | NA

176 participants

Effects of a Machine Learning-based Lower Limb Exercise Training System for Knee Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2026-05-20

Completion:

2027-06-30

Conditions

• Pain
• Knee Osteoarthritis

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT05172245 | RECRUITING | PHASE1

46 participants

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-09-19

Completion:

2027-07-01

Conditions

• Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Head and Neck Carcinoma of Unknown Primary
• Locally Advanced Head and Neck Squamous Cell Carcinoma
• Locally Advanced Hypopharyngeal Squamous Cell Carcinoma
• Locally Advanced Laryngeal Squamous Cell Carcinoma
• Locally Advanced Nasal Cavity Squamous Cell Carcinoma
• Locally Advanced Oral Cavity Squamous Cell Carcinoma
• Locally Advanced Oropharyngeal Squamous Cell Carcinoma
• Locally Advanced Paranasal Sinus Squamous Cell Carcinoma
• Locally Advanced Sinonasal Squamous Cell Carcinoma
• Maxillary Sinus Squamous Cell Carcinoma
• Stage III Hypopharyngeal Carcinoma AJCC v8
• Stage III Laryngeal Cancer AJCC v8
• Stage III Lip and Oral Cavity Cancer AJCC v8
• Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
• Stage III Sinonasal Cancer AJCC v8
• Stage IVA Hypopharyngeal Carcinoma AJCC v8
• Stage IVA Laryngeal Cancer AJCC v8
• Stage IVA Lip and Oral Cavity Cancer AJCC v8
• Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
• Stage IVA Sinonasal Cancer AJCC v8
• Stage IVB Hypopharyngeal Carcinoma AJCC v8
• Stage IVB Laryngeal Cancer AJCC v8
• Stage IVB Lip and Oral Cavity Cancer AJCC v8
• Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8
• Stage IVB Sinonasal Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• RADIATION

No Results Yet

NCT05169515 | RECRUITING | PHASE1

121 participants

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-10-26

Completion:

2029-09-15

Conditions

• Non-Hodgkin Lymphoma

Interventions

• DRUG

No Results Yet

NCT05167318 | ACTIVE_NOT_RECRUITING | NA

150 participants

Frequent Standardized Oral Care to Improve Health Outcomes in Premature Infants in the Neonatal Intensive Care Unit

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-01-15

Completion:

2023-10-02

Conditions

• Microbial Colonization
• Ventilator Associated Pneumonia

Interventions

• OTHER

No Results Yet

NCT05158166 | COMPLETED | PHASE1/PHASE2

22 participants

DaxibotulinumtoxinA Injection for Treatment of Adductor Spasmodic Dysphonia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2023-10-13

Completion:

2025-03-01

Conditions

• Adductor Spasmodic Dysphonia
• Voice Disorders
• Spasmodic Dysphonia

Interventions

• DRUG

Results Available

NCT05155423 | ACTIVE_NOT_RECRUITING

21 participants

A Prospective Study of Performing MRI Simulation in Treatment Position in Spinal Stereotactic Body Radiation Therapy

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2018-04-21

Completion:

2026-05-24

Conditions

• Spinal Metastases

Interventions

• OTHER

No Results Yet

NCT05151822 | RECRUITING | NA

50 participants

Virtual Reality in Awake Surgery : Pilot Study VIRAS

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-05-24

Completion:

2027-05-31

Conditions

• Surgery

Interventions

• OTHER

No Results Yet

NCT05144191 | ACTIVE_NOT_RECRUITING | NA

313 participants

Insignia™ Hip Stem Outcomes Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-02-07

Completion:

2034-04-02

Conditions

• Hip Osteoarthritis
• Avascular Necrosis
• Rheumatoid Arthritis
• Post-traumatic Osteoarthritis
• Femoral Neck Fractures
• Trochanteric Fractures
• Surgery

Interventions

• DEVICE

No Results Yet

NCT05123482 | RECRUITING | PHASE1/PHASE2

460 participants

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-10-18

Completion:

2027-09-29

Conditions

• Breast Cancer
• Biliary Tract Carcinoma
• Ovarian Cancer
• Endometrial Cancer
• Squamous Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05115474 | RECRUITING | PHASE2

170 participants

Study of Screening Brain MRIs in Stage IV Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-12-21

Completion:

2026-06-16

Conditions

• Triple Negative Breast Cancer
• HER2-positive Breast Cancer
• Hormone Receptor-positive Breast Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05110287 | COMPLETED

224 participants

To Evaluate Effectiveness and Safety of GP0109 for Jawline Definition

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-11-15

Completion:

2023-03-15

Conditions

• Jawline Definition Deficiency

Interventions

• DEVICE

Results Available

NCT05108987 | COMPLETED | NA

36 participants

Exercise and Time of Day in Type 2 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-09-25

Completion:

2025-12-17

Conditions

• Diabetes Mellitus, Type 2
• PreDiabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT05096663 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

82 participants

Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-03-15

Completion:

2027-06-30

Conditions

• Advanced Lung Non-Small Cell Carcinoma
• Recurrent Lung Non-Small Cell Carcinoma
• Stage III Lung Cancer AJCC v8
• Stage IIIA Lung Cancer AJCC v8
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8
• Stage IVA Lung Cancer AJCC v8
• Stage IVB Lung Cancer AJCC v8

Interventions

• DIETARY_SUPPLEMENT
• DRUG
• BIOLOGICAL

No Results Yet

NCT05056077 | ACTIVE_NOT_RECRUITING | NA

353 participants

Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-10-21

Completion:

2027-04-30

Conditions

• Bladder Cancer
• Breast Cancer
• Colon Cancer
• Endometrial Cancer
• Ovarian Cancer
• Rectal Cancer
• Prostate Cancer
• Renal Cell Carcinoma
• Kidney Cancer

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT05051657 | COMPLETED | NA

28 participants

Evaluation of the Express Plus Range

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-06-14

Completion:

2025-09-30

Conditions

• Phenylketonurias
• PKU
• Homocystinuria
• Maple Syrup Urine Disease
• Hereditary Tyrosinemia
• Glutaric Acidemia I

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT05039554 | RECRUITING | NA

127 participants

Randomized Trial of ACT and a Care Management App in Primary Care-based Buprenorphine Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2023-02-02

Completion:

2027-04-27

Conditions

• Opioid-use Disorder
• Chronic Pain

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05034536 | ACTIVE_NOT_RECRUITING | PHASE2

36 participants

PD-1 Antibody Therapy + Infliximab for Metastatic Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-02-07

Completion:

2026-06-30

Conditions

• Metastatic Melanoma

Interventions

• DRUG

No Results Yet

NCT05034289 | COMPLETED | NA

81 participants

Promoting INformed Approaches in Precision Oncology and ImmuNoTherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-07-12

Completion:

2023-05-19

Conditions

• Clinical Trials
• Immunotherapy

Interventions

• BEHAVIORAL

Results Available

NCT05020951 | ACTIVE_NOT_RECRUITING

118 participants

Pilot Study to Enable Electronic Laboratory Data Transfer From Participating Institutions to MediData/RAVE

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2021-08-28

Completion:

2023-07-31

Conditions

• Accurate and Complete Data Acquisition for Clinical Trials

Interventions

• OTHER

No Results Yet

NCT05010603 | RECRUITING

10000 participants

Late Onset Alzheimer's Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2016-11-15

Completion:

2027-04-30

Conditions

• Alzheimer Disease

Interventions

• GENETIC
• OTHER

No Results Yet

NCT04990128 | NOT_YET_RECRUITING | PHASE3

100 participants

Bone Marrow Aspirate Concentrate Versus Triamcinolone Injection For Hip Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2026-05-15

Completion:

2027-07-31

Conditions

• Hip Osteoarthritis

Interventions

• COMBINATION_PRODUCT
• DRUG

No Results Yet

NCT04984733 | COMPLETED | PHASE2

13 participants

Temozolomide + Nivolumab in MGMT Methylated Oesophagogastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-09-28

Completion:

2024-10-23

Conditions

• Adenocarcinoma - GEJ
• Cancer of Esophagus

Interventions

• DRUG

No Results Yet

NCT04968873 | COMPLETED | NA

13 participants

Common Bile Duct Pressure After Surgical Exploration

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2001-03-31

Completion:

2001-08-31

Conditions

• Choledocholithiasis

Interventions

• PROCEDURE

No Results Yet

NCT04965038 | TERMINATED | PHASE3

127 participants

Early Reperfusion Therapy With Intravenous Thrombolysis for Recovery of VISION in Acute Central Retinal Artery Occlusion

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2022-10-10

Completion:

2026-03-23

Conditions

• Central Retinal Artery Occlusion

Interventions

• DRUG

No Results Yet

NCT04941716 | RECRUITING | PHASE2

20 participants

Acalabrutinib in Combination With Venetoclax for the Treatment of Refractory or Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, The AVENUE-2 Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2023-05-31

Completion:

2027-08-10

Conditions

• Recurrent Chronic Lymphocytic Leukemia
• Recurrent Small Lymphocytic Lymphoma
• Refractory Chronic Lymphocytic Leukemia
• Refractory Small Lymphocytic Lymphoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04928664 | COMPLETED | PHASE4

78 participants

Continuous vs Liposomal Bupivacaine Interscalene Block for Proximal Humeral Fracture (CLIP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-09-09

Completion:

2025-12-13

Conditions

• Shoulder Fractures

Interventions

• DRUG

No Results Yet

NCT04917848 | ACTIVE_NOT_RECRUITING | NA

124 participants

A Study of a Telemedicine Program for Older Adults With Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-06-01

Completion:

2026-06-01

Conditions

• Cancer

Interventions

• OTHER

No Results Yet

NCT04857983 | COMPLETED | PHASE2/PHASE3

62 participants

Memantine Augmentation of Targeted Cognitive Training in Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2021-07-06

Completion:

2025-03-30

Conditions

• Schizophrenia
• Schizoaffective Disorder

Interventions

• DRUG

Results Available