Clinical Trials

NCT04108091 | COMPLETED

1214 participants

Vyndaqel Capsules Special Investigation (ATTR-CM)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2019-10-03

Completion:

2025-03-27

Conditions

• Transthyretin (TTR) Amyloid Cardiomyopathy

Interventions

• DRUG

Results Available

NCT04069624 | COMPLETED | NA

900 participants

Kentucky Women's Justice Community Opioid Innovation Network

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-12-17

Completion:

2026-04-30

Conditions

• Opioid-use Disorder

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04067830 | RECRUITING | PHASE2

220 participants

Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2019-03-20

Completion:

2027-03-22

Conditions

• Stage I Lung Cancer AJCC v8
• Stage IA1 Lung Cancer AJCC v8
• Stage IA2 Lung Cancer AJCC v8
• Stage IA3 Lung Cancer AJCC v8
• Stage IB Lung Cancer AJCC v8
• Stage II Lung Cancer AJCC v8
• Stage IIA Lung Cancer AJCC v8
• Stage IIB Lung Cancer AJCC v8
• Stage IIIA Lung Cancer AJCC v8
• Stage IIIB Lung Cancer AJCC v8

Interventions

• OTHER
• PROCEDURE
• DEVICE

No Results Yet

NCT04060498 | COMPLETED | NA

152 participants

Mindfulness Intervention and Relapse in Psychosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2019-06-01

Completion:

2023-10-01

Conditions

• Psychosis

Interventions

• BEHAVIORAL

No Results Yet

NCT04049058 | TERMINATED

10 participants

Evaluation of Quality of Life After Orthognathic Surgery in a Cleft Lip and Palate Context

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2019-06-30

Completion:

2021-06-03

Conditions

• Palate, Cleft

No Results Yet

NCT04033237 | COMPLETED | PHASE1/PHASE2

30 participants

Project 4, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Pregnant Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2019-08-21

Completion:

2024-04-17

Conditions

• Tobacco Use Disorder

Interventions

• OTHER

Results Available

NCT04032418 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

Pembrolizumab Every 12 Weeks Versus Every 3 Weeks in Treating Patients With Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-08-13

Completion:

2025-03-14

Conditions

• Lung Non-Small Cell Carcinoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04002882 | RECRUITING

90 participants

Role of Body Fat Distribution in Metabolic and Pulmonary Decline in Cystic Fibrosis (ORBIT-CF)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2019-07-08

Completion:

2027-05-31

Conditions

• Cystic Fibrosis

No Results Yet

NCT04002297 | ACTIVE_NOT_RECRUITING | PHASE3

510 participants

A Study to Investigate the Efficacy of Zanubrutinib Plus Rituximab Compared With Bendamustine Plus Rituximab in Adults With Previously Untreated Mantle Cell Lymphoma Who Are Ineligible for Stem Cell Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2019-08-20

Completion:

2027-03-31

Conditions

• Mantle Cell Lymphoma; Non-Hodgkin Lymphoma

Interventions

• DRUG

No Results Yet

NCT03961347 | COMPLETED | PHASE2

46 participants

Lactobacillus Johnsonii Supplementation in Adults With T1D

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-02-01

Completion:

2026-03-18

Conditions

• Type 1 Diabetes (T1D)

Interventions

• DRUG

No Results Yet

NCT03933670 | RECRUITING | PHASE2

60 participants

Hyperpolarized Pyruvate (13C) MR Imaging in Monitoring Patients With Prostate Cancer on Active Surveillance

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2018-07-18

Completion:

2027-12-31

Conditions

• Prostate Adenocarcinoma
• Prostate Cancer

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT03905525 | COMPLETED | PHASE2

273 participants

Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjogren's Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2019-10-01

Completion:

2022-09-28

Conditions

• Sjögren Syndrome

Interventions

• DRUG
• OTHER

Results Available

NCT03901014 | COMPLETED | NA

4 participants

Investigating the Production of Lipoproteins and Acetyl-CoA During a Ketogenic Diet

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2019-03-29

Completion:

2019-04-18

Conditions

• Cholesterol Metabolism
• Ketone Metabolism

Interventions

• OTHER

No Results Yet

NCT03875378 | RECRUITING | PHASE2

66 participants

Transdermal Estrogen in Women With Anorexia Nervosa

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-08-28

Completion:

2028-08-31

Conditions

• Anorexia Nervosa

Interventions

• DRUG

No Results Yet

NCT03851445 | RECRUITING | PHASE2/PHASE3

10000 participants

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2019-02-06

Completion:

2029-01-28

Conditions

• Previously Treated Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT03816319 | SUSPENDED | PHASE1

42 participants

TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes With Increased Blasts

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2025-03-12

Completion:

2026-10-24

Conditions

• Myelodysplastic Syndrome With Excess Blasts
• Recurrent Acute Myeloid Leukemia
• Recurrent Myelodysplastic Syndrome
• Recurrent Myelodysplastic Syndrome/Acute Myeloid Leukemia
• Refractory Acute Myeloid Leukemia
• Refractory Myelodysplastic Syndrome
• Refractory Myelodysplastic Syndrome/Acute Myeloid Leukemia

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT03808922 | RECRUITING | PHASE3

274 participants

Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2019-05-23

Completion:

2028-09-01

Conditions

• Lower Respiratory Tract Infection
• Parainfluenza
• Immunocompromised
• COVID-19

Interventions

• DRUG

No Results Yet

NCT03790293 | COMPLETED | PHASE3

80 participants

Clinical and Immunological Long-term Follow-up of Patients With Pemphigus Included in the "RITUXIMAB 3" Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2018-11-17

Completion:

2019-04-19

Conditions

• Autoimmune Diseases

Interventions

• DRUG

No Results Yet

NCT03774654 | ACTIVE_NOT_RECRUITING | PHASE1

13 participants

CD19.CAR Allogeneic NKT for Patients With Relapsed or Refractory B-Cell Malignancies (ANCHOR)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2020-04-14

Completion:

2025-06-05

Conditions

• Refractory B-Cell Non-Hodgkin Lymphoma
• Refractory B-Cell Small Lymphocytic Lymphoma
• Relapsed Adult ALL
• Relapsed CLL
• Relapsed Non Hodgkin Lymphoma

Interventions

• GENETIC

No Results Yet

NCT03710109 | TERMINATED

150 participants

Evaluation of an EEG Based Concussion System

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2018-10-23

Completion:

2025-03-17

Conditions

• Concussion

Interventions

• OTHER

No Results Yet

NCT03706664 | ACTIVE_NOT_RECRUITING | NA

226 participants

Small Bowel Deep Learning Algorithm Project

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2019-03-01

Completion:

2028-08-31

Conditions

• Crohn Disease

Interventions

• OTHER

No Results Yet

NCT03588299 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

11 participants

Study to Test the Safety and How Well Patients With Severe Hemophilia A Respond to Treatment With BAY 2599023 (DTX 201), a Drug Therapy That Delivers a Healthy Version of the Defective Factor VIII Gene Into the Nucleus of Liver Cells Using an Altered, Non-infectious Virus (AAV) as a "Shuttle"

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2018-11-07

Completion:

2026-11-03

Conditions

• Hemophilia A

Interventions

• DRUG

No Results Yet

NCT03587740 | ACTIVE_NOT_RECRUITING | PHASE2

111 participants

ATOP TRIAL: T-DM1 in HER2 Positive Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2018-08-22

Completion:

2025-03-03

Conditions

• Breast Cancer

Interventions

• DRUG

Results Available

NCT03528980 | ACTIVE_NOT_RECRUITING

59 participants

Impact of Weight Loss Induced by Bariatric Surgery or Nutritional Management on Sexual Function in Men With Severe Obesity

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2012-05-21

Completion:

2019-01-31

Conditions

• Obesity
• Bariatric Surgery Candidate

No Results Yet

NCT03409614 | COMPLETED | PHASE3

789 participants

Combinations of Cemiplimab (Anti-PD-1 Antibody) and Platinum-based Doublet Chemotherapy in Patients With Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2018-03-06

Completion:

2025-02-27

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG
• OTHER

Results Available

NCT03388788 | ACTIVE_NOT_RECRUITING

17 participants

Body Weight, Sleep, and Heart Health

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2018-05-01

Completion:

2024-09-30

Conditions

• Cardiovascular Risk Factor
• Circadian Dysregulation
• Obesity

Interventions

• COMBINATION_PRODUCT

Results Available

NCT03386500 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

24 participants

Safety Study of BMX-001 (Radio-protector) in Patients With Newly Diagnosed Anal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2017-11-28

Completion:

2026-10-31

Conditions

• Anal Cancer, Squamous Cell Carcinoma
• Radiation Exposure

Interventions

• DRUG

No Results Yet

NCT03370263 | COMPLETED

1514 participants

BENLYSTA® Special Drug Use Investigation

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2018-01-15

Completion:

2025-07-31

Conditions

• Systemic Lupus Erythematosus

Interventions

• DRUG

Results Available

NCT03353584 | RECRUITING | NA

76 participants

Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2018-02-05

Completion:

2026-11-30

Conditions

• Sickle Cell Disease
• Vaso-occlusive Crisis

Interventions

• OTHER

No Results Yet

NCT03326921 | RECRUITING | PHASE1

24 participants

HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2018-02-23

Completion:

2027-10-16

Conditions

• Juvenile Myelomonocytic Leukemia
• Recurrent Acute Biphenotypic Leukemia
• Recurrent Acute Undifferentiated Leukemia
• Recurrent Childhood Acute Lymphoblastic Leukemia
• Recurrent Childhood Acute Myeloid Leukemia
• Refractory Acute Lymphoblastic Leukemia
• Refractory Adult Acute Lymphoblastic Leukemia
• Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive
• Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm
• Recurrent Myelodysplastic Syndrome
• Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm
• Refractory Myelodysplastic Syndrome
• Acute Undifferentiated Leukemia
• Mixed Phenotype Acute Leukemia
• Recurrent Chronic Myeloid Leukemia, BCR-ABL1 Positive
• Refractory Chronic Myeloid Leukemia, BCR-ABL1 Positive
• Recurrent Acute Lymphoblastic Leukemia
• Recurrent Acute Myeloid Leukemia
• Myelodysplastic Syndrome
• Acute Myeloid Leukemia
• Acute Lymphoblastic Leukemia
• Acute Biphenotypic Leukemia
• Chronic Myeloid Leukemia
• Chronic Myelomonocytic Leukemia
• Minimal Residual Disease
• Recurrent Chronic Myelomonocytic Leukemia
• Recurrent Mixed Phenotype Acute Leukemia
• Leukemia
• Chronic Myeloid Leukemia, BCR-ABL1 Positive

Interventions

• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT03279237 | COMPLETED | PHASE1

25 participants

A Pilot Study of FOLFIRINOX in Combination With Neoadjuvant Radiation for Gastric and GE Junction Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2017-10-24

Completion:

2018-09-26

Conditions

• GastroEsophageal Cancer

Interventions

• DRUG
• RADIATION

Results Available

NCT03258658 | RECRUITING | PHASE1

10 participants

Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2026-05-31

Completion:

2028-12-31

Conditions

• Urologic Diseases
• Male Urogenital Diseases
• Urethral Stricture
• Urethral Injury

Interventions

• BIOLOGICAL

No Results Yet

NCT03191149 | RECRUITING | PHASE2

46 participants

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2018-04-25

Completion:

2027-06-30

Conditions

• Advanced Lung Non-Small Cell Carcinoma
• Recurrent Lung Non-Small Cell Carcinoma
• Stage IIIB Lung Non-Small Cell Cancer AJCC v7
• Stage IV Lung Non-Small Cell Cancer AJCC v7

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT03178799 | ENROLLING_BY_INVITATION

400 participants

Randomized Fracture Liaison Services

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2017-06-23

Completion:

2028-12-31

Conditions

• Osteoporosis Fracture

No Results Yet

NCT03171311 | ACTIVE_NOT_RECRUITING | NA

1201 participants

The OCTOBER Trial - European Trial on Optical Coherence Tomography Optimized Bifurcation Event Reduction (OCTOBER)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2017-07-05

Completion:

2022-03-25

Conditions

• Ischaemic Heart Disease
• Ischemic Heart Disease

Interventions

• PROCEDURE

No Results Yet

NCT02947750 | RECRUITING | PHASE2

150 participants

Neurovascular Transduction During Exercise in Chronic Kidney Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2016-10-31

Completion:

2027-04-30

Conditions

• Renal Insufficiency, Chronic

Interventions

• DRUG
• OTHER
• DIETARY_SUPPLEMENT

No Results Yet

NCT02943642 | WITHDRAWN | PHASE2

0 participants

Safety and Effectiveness of A-dmDT390-bisFv(UCHT1) Fusion Protein in Subjects With Mycosis Fungoides

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2026-05-31

Completion:

2026-05-13

Conditions

• Mycosis Fungoides

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT02942290 | ACTIVE_NOT_RECRUITING | PHASE1

129 participants

A Study Evaluating Venetoclax in Combination With Azacitidine in Participants With Treatment-Naïve Higher-Risk Myelodysplastic Syndromes (MDS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2017-01-12

Completion:

2027-01-31

Conditions

• Myelodysplastic Syndromes (MDS)

Interventions

• DRUG

No Results Yet

NCT02860091 | TERMINATED

26 participants

Blood Ropivacaine Concentrations Following Chest Wall Nerve Block Continuous Infusion

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-18

Start Date:

2018-10-01

Completion:

2026-05-14

Conditions

• Pain, Postoperative

Interventions

• DRUG

No Results Yet

NCT02797470 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

11 participants

Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-18

Start Date:

2016-06-23

Completion:

2021-05-13

Conditions

• HIV Infection
• Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
• Plasmablastic Lymphoma
• Recurrent Adult Hodgkin Lymphoma
• Recurrent Adult Non-Hodgkin Lymphoma
• Recurrent Burkitt Lymphoma
• Recurrent Follicular Lymphoma
• Stage III Follicular Lymphoma
• Stage III Mantle Cell Lymphoma
• Stage IV Follicular Lymphoma
• Stage IV Mantle Cell Lymphoma

Interventions

• PROCEDURE
• DRUG
• OTHER
• BIOLOGICAL

Results Available