Clinical Trials

NCT04947254 | RECRUITING | PHASE2

200 participants

Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-08-05

Completion:

2026-06-07

Conditions

• Prostate Carcinoma
• Stage IIC Prostate Cancer AJCC v8
• Stage III Prostate Cancer AJCC v8
• Stage IIIA Prostate Cancer AJCC v8
• Stage IIIB Prostate Cancer AJCC v8
• Stage IIIC Prostate Cancer AJCC v8
• Stage IVA Prostate Cancer AJCC v8

Interventions

• DRUG
• RADIATION
• PROCEDURE

No Results Yet

NCT04927780 | ACTIVE_NOT_RECRUITING | PHASE3

378 participants

Perioperative or Adjuvant mFOLFIRINOX for Resectable Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-09-07

Completion:

2027-01-31

Conditions

• Pancreatic Cancer
• Pancreatic Ductal Adenocarcinoma
• Resectable Pancreatic Adenocarcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04924088 | ACTIVE_NOT_RECRUITING | NA

85 participants

Medical-legal Partnerships to Prevent Evictions and Homelessness Among Veterans

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2022-02-01

Completion:

2026-03-01

Conditions

• Homelessness
• Mental Health

Interventions

• BEHAVIORAL

No Results Yet

NCT04921488 | COMPLETED | NA

194 participants

Interest of Artificial Intelligence in Cancer Screening Colonoscopy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-10-21

Completion:

2023-01-25

Conditions

• Colonoscopy
• Colorectal Neoplasms
• Intestinal Polyps
• Deep Learning

Interventions

• DEVICE

No Results Yet

NCT04877041 | COMPLETED | NA

111 participants

Exercise and Cardiac Stunning During HD

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2023-03-01

Completion:

2026-01-14

Conditions

• End-stage Kidney Disease
• Hemodialysis

Interventions

• BEHAVIORAL

No Results Yet

NCT04874220 | RECRUITING | NA

70 participants

Neural Correlates of Real World Spatial Navigation in Humans

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2020-09-30

Completion:

2026-06-30

Conditions

• Memory, Delayed

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT04867317 | RECRUITING | PHASE3

172 participants

Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2025-01-13

Completion:

2027-02-28

Conditions

• Adult Growth Hormone Deficiency
• Mild Traumatic Brain Injury

Interventions

• DRUG
• OTHER

No Results Yet

NCT04859725 | ACTIVE_NOT_RECRUITING | NA

10 participants

HyperSpectral Imaging in Low Grade Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-05-31

Completion:

2026-05-31

Conditions

• Low Grade Glioma of Brain

Interventions

• DEVICE

No Results Yet

NCT04843709 | COMPLETED | PHASE1/PHASE2

39 participants

A Study of MRG004A in Patients With Tissue Factor Positive Advanced or Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-07-26

Completion:

2024-03-20

Conditions

• Advanced or Metastatic Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04837040 | ACTIVE_NOT_RECRUITING | PHASE3

58 participants

A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-05-12

Completion:

2023-07-10

Conditions

• Acromegaly

Interventions

• DRUG

Results Available

NCT04836923 | COMPLETED | NA

81 participants

LIFT Intervention in Liver Transplant Candidates

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2020-10-01

Completion:

2023-03-01

Conditions

• Frailty
• Cirrhosis
• Liver Transplant

Interventions

• BEHAVIORAL

Results Available

NCT04799015 | COMPLETED | PHASE4

162 participants

Dexamethasone for Post Traumatic Headache

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-06-25

Completion:

2024-11-17

Conditions

• Post-Traumatic Headache

Interventions

• DRUG

Results Available

NCT04795843 | RECRUITING | NA

200 participants

Exercise and Patient Education Compared With Usual Care in Patients With Hip Dysplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-04-16

Completion:

2027-07-31

Conditions

• Hip Dysplasia

Interventions

• OTHER

No Results Yet

NCT04776837 | COMPLETED

159 participants

Predicting Disease Progression and/or Recurrence in Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2019-05-15

Completion:

2021-11-19

Conditions

• Patient Reported Outcome Measures
• Colorectal Cancer
• Pancreatic Cancer
• Biliary Tract Cancer
• Esophageal Cancer
• Metastatic Cancer
• Disease Progression
• Survival Analysis

Interventions

• BEHAVIORAL

No Results Yet

NCT04765020 | RECRUITING | PHASE2/PHASE3

56 participants

Cardiorespiratory Fitness in Children and Adolescents After Cancer Treatment.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-06-21

Completion:

2027-12-31

Conditions

• All Types of Pediatric Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT04750915 | ACTIVE_NOT_RECRUITING

566398 participants

NIH-AARP Diet and Health Secondary Research Study Based on OH95CN025 Data

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2021-02-09

Completion:

2050-12-31

Conditions

• Cancer
• Mortality
• Chronic Diseases

No Results Yet

NCT04750876 | RECRUITING | NA

40 participants

Early Evaluation of the Introduction of Pre- and Post-operative Psychological and Physiotherapeutic Follow-up in Vascular Surgery in Amputee Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-04-08

Completion:

2027-04-18

Conditions

• Amputation

Interventions

• OTHER

No Results Yet

NCT04747431 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

30 participants

A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-09-14

Completion:

2028-08-31

Conditions

• Frontotemporal Dementia
• FTD
• FTD-GRN
• Dementia Frontotemporal
• C9orf72

Interventions

• DRUG

No Results Yet

NCT04728165 | COMPLETED

27 participants

Anti-Inflammatory Effects of Time-Restricted Feeding

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2021-06-09

Completion:

2023-07-28

Conditions

• Psoriasis
• Systemic Inflammation

No Results Yet

NCT04716725 | TERMINATED | PHASE2

15 participants

68Ga-PSMA-11 PET for the Diagnosis of Metastatic Castration Resistant Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-09-28

Completion:

2023-09-30

Conditions

• Castration-Resistant Prostate Carcinoma
• Metastatic Prostate Carcinoma
• Stage IV Prostate Cancer AJCC v8
• Stage IVA Prostate Cancer AJCC v8
• Stage IVB Prostate Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE

Results Available

NCT04674969 | RECRUITING

5000 participants

Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2021-03-29

Completion:

2028-01-31

Conditions

• Peripheral Vascular Diseases

Interventions

• DEVICE

No Results Yet

NCT04663750 | RECRUITING | PHASE3

210 participants

Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative (Wet) Age-related Macular Degeneration (TIGER).

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-04-16

Completion:

2028-12-31

Conditions

• Eye Diseases
• Macular Degeneration, Wet
• Sub-Macular Hemorrhage

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04662255 | ACTIVE_NOT_RECRUITING | PHASE3

500 participants

Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-04-08

Completion:

2027-01-31

Conditions

• Lymphoma, Mantle-Cell

Interventions

• DRUG

No Results Yet

NCT04627974 | ACTIVE_NOT_RECRUITING

70 participants

Long-term Effectiveness, Safety, and Performance of the Evoke Closed-Loop SCS System to Treat Patients With Chronic Pain of the Trunk and/or Limbs

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2020-08-05

Completion:

2023-04-03

Conditions

• Chronic Pain

Interventions

• DEVICE

No Results Yet

NCT04622319 | ACTIVE_NOT_RECRUITING | PHASE3

1600 participants

A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2020-12-04

Completion:

2025-07-02

Conditions

• HER2-Positive Primary Breast Cancer
• Residual Invasive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04599036 | ACTIVE_NOT_RECRUITING | NA

3 participants

EMG Controlled Device in Acute Rehabilitation After Acute Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2020-10-07

Completion:

2026-09-30

Conditions

• Stroke

Interventions

• DEVICE

No Results Yet

NCT04576377 | COMPLETED | PHASE4

977 participants

Dynamics of the Immune Responses to Repeat Influenza Vaccination Exposures

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2020-10-05

Completion:

2025-12-31

Conditions

• Influenza, Human

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04576052 | COMPLETED

397 participants

Long-term Coated and Non-coated Tibia Nails

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2020-07-18

Completion:

2025-06-30

Conditions

• Implant Infection

No Results Yet

NCT04566328 | RECRUITING | PHASE3

1450 participants

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-02-24

Completion:

2027-12-31

Conditions

• Plasma Cell Myeloma
• RISS Stage I Plasma Cell Myeloma
• RISS Stage II Plasma Cell Myeloma

Interventions

• DRUG
• BIOLOGICAL
• OTHER

No Results Yet

NCT04565496 | WITHDRAWN | PHASE2

0 participants

Phase 2 Study of Neoadjuvant PEMbrolizumab Before Radical PROstatectomy in High-risk Prostate Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2023-04-10

Completion:

2025-01-01

Conditions

• Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT04529967 | RECRUITING

15000 participants

Child-Parent Familial Hypercholesterolemia Screening

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2025-04-01

Completion:

2026-09-30

Conditions

• Familial Hypercholesterolemia

Interventions

• OTHER

No Results Yet

NCT04526691 | ACTIVE_NOT_RECRUITING | PHASE1

145 participants

Datopotamab Deruxtecan (Dato-DXd) in Combination With Pembrolizumab With or Without Platinum Chemotherapy in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung02)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2020-09-15

Completion:

2024-04-14

Conditions

• Advanced or Metastatic NSCLC

Interventions

• DRUG

No Results Yet

NCT04524273 | ACTIVE_NOT_RECRUITING | PHASE3

238 participants

Myasthenia Gravis Inebilizumab Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2020-10-15

Completion:

2024-05-28

Conditions

• Myasthenia Gravis

Interventions

• DRUG

Results Available

NCT04472338 | RECRUITING

450 participants

Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2020-05-21

Completion:

2030-08-31

Conditions

• Prostate Carcinoma

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04469842 | RECRUITING | EARLY_PHASE1

48 participants

Early Use of Long-acting Tacrolimus in Lung Transplant Recipients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2023-12-01

Completion:

2027-06-30

Conditions

• Lung Transplant; Complications

Interventions

• DRUG

No Results Yet

NCT04451863 | ACTIVE_NOT_RECRUITING | PHASE1

45 participants

Analgesic and Subjective Effects of Terpenes

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-12-15

Completion:

2025-11-12

Conditions

• Pain
• Abuse, Drug

Interventions

• DRUG

No Results Yet

NCT04438382 | TERMINATED | PHASE2

1 participants

Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2021-01-07

Completion:

2023-12-21

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm
• Malignant Solid Neoplasm
• Steroid-Refractory Pneumonitis

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04423211 | RECRUITING | PHASE3

804 participants

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2020-10-08

Completion:

2032-12-31

Conditions

• Biochemically Recurrent Prostate Carcinoma
• Metastatic Prostate Carcinoma
• Prostate Adenocarcinoma
• Stage IVB Prostate Cancer AJCC v8

Interventions

• RADIATION
• DRUG
• PROCEDURE
• OTHER

No Results Yet

NCT04421248 | RECRUITING | PHASE4

214 participants

Biomarker Validation in Motor System Physiology in Attention Deficit Hyperactivity Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-15

Start Date:

2020-09-01

Completion:

2026-02-09

Conditions

• Attention Deficit Hyperactivity Disorder Combined

Interventions

• DRUG

No Results Yet

NCT04419870 | RECRUITING

400 participants

Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-15

Start Date:

2020-10-21

Completion:

2027-05-01

Conditions

• Mitochondrial Disease

No Results Yet