Clinical Trials

NCT07278427 | RECRUITING

400 participants

Reducing Parental Substance Use and Enhancing Family Resilience Among Rural Families Through Ohio START

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-04-27
Completion:: 2028-02-28

Conditions

Substance Use Disorder (SUD)
Rural Health
Family Resilience
Child Maltreatment
Child Well-beiing
Substance Use Recovery

Interventions

BEHAVIORAL

No Results Yet

NCT07271472 | COMPLETED | NA

60 participants

Oxidative Stress Effects of TIVA, CIVA, and Balanced Anesthesia in VATS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-12-01
Completion:: 2026-05-01

Conditions

VATS
Video Assisted Thoracoscopic Surgery

Interventions

DRUG

No Results Yet

NCT07267936 | ACTIVE_NOT_RECRUITING | NA

231 participants

Interventions for Maximizing Patient And Family Smoking Cessation Together

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-07-07
Completion:: 2026-04-22

Conditions

Smoking Cessation

Interventions

OTHER

No Results Yet

NCT07265674 | RECRUITING | PHASE3

480 participants

A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-04-30
Completion:: 2027-10-31

Conditions

Advanced Biliary Tract Cancer
Biliary Tract Cancer (BTC)

Interventions

DRUG
OTHER

No Results Yet

NCT07265479 | RECRUITING | PHASE3

180 participants

A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-12-29
Completion:: 2028-01-31

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT07264140 | NOT_YET_RECRUITING | NA

116 participants

Assessing and Improving Misuse of Inhalers in COPD Outpatients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-06-01
Completion:: 2029-05-31

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Interventions

BEHAVIORAL

No Results Yet

NCT07261787 | RECRUITING | PHASE4

76 participants

Duration of Surfactant Administration and Impact on Stabilisation of Vital Parameters in Very Preterm Neonates: 1 Minutes Versus 5 Minutes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-02-20
Completion:: 2028-07-01

Conditions

Neonates and Preterm Infants
Infant Respiratory Distress Syndrome
Surfactant Deficiency Syndrome Neonatal
Surfactant
Cerebral Oxygenation
Cerebral Oxygen Saturation

Interventions

DRUG

No Results Yet

NCT07256301 | RECRUITING | PHASE1

24 participants

A Phase Ib, Multicenter, Open-Label Study of Multiple-Dose EA5 in Adults With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2024-01-03
Completion:: 2026-08-31

Conditions

PNH - Paroxysmal Nocturnal Hemoglobinuria

Interventions

BIOLOGICAL

No Results Yet

NCT07253740 | COMPLETED | NA

60 participants

Interscalene Versus Infraspinatus-Teres Minor Blocks for Arthroscopic Shoulder Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-01-01
Completion:: 2026-05-01

Conditions

Arthroscopic Shoulder Surgery

Interventions

PROCEDURE

No Results Yet

NCT07247110 | RECRUITING | PHASE1

250 participants

A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-12-16
Completion:: 2030-12-01

Conditions

Malignant Neoplasm

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT07246499 | ACTIVE_NOT_RECRUITING | NA

25 participants

Multicentre Study on the Impact of Transmucosal Abutment Surface Characteristics on Peri-implant Tissues.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-11-01
Completion:: 2026-03-01

Conditions

Peri-implant Tissue Healing Assessed by Proteomic Analysis

Interventions

DEVICE

No Results Yet

NCT07241715 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

300 participants

Conversion Surgery for Gastric Cancer With Peritoneal Metastases (CONVERGENCE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-02-21
Completion:: 2034-01-31

Conditions

Gastric Cancer Stage IV
Peritoneal Metastasis

Interventions

PROCEDURE
DRUG

No Results Yet

NCT07234279 | NOT_YET_RECRUITING

30 participants

Nellcor™ Investigational Device Sitting-Walking Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-06-30
Completion:: 2026-07-31

Conditions

Oxygen Saturation

No Results Yet

NCT07231978 | COMPLETED | PHASE1

69 participants

A Study to Learn How Different Forms of the Study Medicine Called Prazosin Are Taken up Into the Blood in Healthy Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-11-14
Completion:: 2026-04-03

Conditions

Healthy

Interventions

DRUG

No Results Yet

NCT07230990 | RECRUITING | NA

80 participants

Mechanisms Of Orbitofrontal Stimulation in Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-04-15
Completion:: 2030-12-31

Conditions

Major Depressive Disorder (MDD)

Interventions

DEVICE

No Results Yet

NCT07230730 | RECRUITING | PHASE3

900 participants

A Trial to Evaluate the Efficacy and Safety of SHR-1918 in Patients With Hyperlipidemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-01-13
Completion:: 2027-10-31

Conditions

Hyperlipidemia

Interventions

DRUG

No Results Yet

NCT07226583 | NOT_YET_RECRUITING | NA

20 participants

Using a Personalized Decision Support Tool to Help People With Type 1 Diabetes Manage Exercise

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-04-30
Completion:: 2026-08-31

Conditions

Type 1 Diabetes Mellitis
Type 1 Diabetes (T1D)
Type 1 Diabetes Mellitus (T1DM)
Exercise Physiology

Interventions

BEHAVIORAL
DEVICE

No Results Yet

NCT07226531 | ACTIVE_NOT_RECRUITING

300 participants

Utilization and Effectiveness of Ritlecitinib in a Real-World Population With Severe AA in the US

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-12-22
Completion:: 2026-05-29

Conditions

Alopecia Areata

Interventions

DRUG

No Results Yet

NCT07224425 | RECRUITING | PHASE1

69 participants

A Study of BI 3810944 in Patients With Advanced Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-02-24
Completion:: 2029-10-05

Conditions

Solid Tumours
Melanoma

Interventions

DRUG

No Results Yet

NCT07223203 | RECRUITING | PHASE3

125 participants

TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-12-12
Completion:: 2027-12-27

Conditions

Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy
hATTR-PN

Interventions

DRUG

No Results Yet

NCT07221890 | ACTIVE_NOT_RECRUITING | NA

1325 participants

A Trial of Academic Detailing to Promote Prescribing of Biosimilars

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-11-06
Completion:: 2026-12-31

Conditions

Autoimmune Diseases
Rheumatoid Arthritis (RA)
Inflammatory Bowel Disease (IBD)
Psoriasis (PsO)

Interventions

OTHER

No Results Yet

NCT07221435 | COMPLETED | NA

5 participants

Microlearning-Based Health Education for Ambulatory Surgery Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-10-30
Completion:: 2026-02-12

Conditions

Microlearning

Interventions

BEHAVIORAL

No Results Yet

NCT07221149 | RECRUITING | PHASE2/PHASE3

690 participants

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-03-13
Completion:: 2030-11-08

Conditions

Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT07220577 | ACTIVE_NOT_RECRUITING | PHASE2

34 participants

Phase 2a Study to Assess the Efficacy,Safety and Tolerability of GIA632 in Adult Participants With Moderate to Severe Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-11-10
Completion:: 2027-05-17

Conditions

Atopic Dermatitis

Interventions

DRUG
OTHER

No Results Yet

NCT07218146 | RECRUITING | PHASE3

480 participants

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-11-30
Completion:: 2028-06-30

Conditions

Small-cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT07216625 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:: 2026-05-14

No Results Yet

NCT07216404 | RECRUITING | PHASE2

10 participants

Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-01-01
Completion:: 2027-10-31

Conditions

Lung Non-Small Cell Carcinoma
Unipolar Depression

Interventions

PROCEDURE
OTHER
DRUG

No Results Yet

NCT07215559 | RECRUITING | PHASE2

200 participants

A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-10-16
Completion:: 2027-03-31

Conditions

Obesity
Overweight
Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT07214727 | RECRUITING | PHASE1

50 participants

A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-10-15
Completion:: 2030-03-06

Conditions

Alzheimer's Disease

Interventions

DRUG

No Results Yet

NCT07214311 | RECRUITING | PHASE2/PHASE3

240 participants

Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-02-03
Completion:: 2028-09-30

Conditions

Prosthetic-joint Infection

Interventions

DRUG

No Results Yet

NCT07210255 | RECRUITING | NA

192 participants

SAINT in Postpartum Depression (PPD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-11-01
Completion:: 2029-04-30

Conditions

Postpartum Depression (PPD)

Interventions

DEVICE

No Results Yet

NCT07198945 | NOT_YET_RECRUITING | NA

546 participants

Six Versus Twelve Month Index Follow-up After Large Colon Polyp Resection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-05-31
Completion:: 2029-11-30

Conditions

Colon Cancer
Colon Polyp
Adenoma
Serrated Polyp
Recurrence, Local Neoplasm
Endoscopic Resection

Interventions

PROCEDURE

No Results Yet

NCT07198607 | COMPLETED

100 participants

Pistacia Lentiscus Oil Nasal Drops for Preventing Recurrence of Chronic Rhinosinusitis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-14
Start Date:: 2023-04-04
Completion:: 2025-03-03

Conditions

Chronic Rhinosinusitis Without Nasal Polyps
Chronic Rhinosinusitis (Diagnosis)

Interventions

OTHER

No Results Yet

NCT07197645 | RECRUITING | PHASE1

33 participants

Samarium Optimized for Long-lasting Analgesia in Cancerous End-stage Bone Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-10-21
Completion:: 2027-04-26

Conditions

Bone Pain
Metastatic Bone Tumor
Bone Metastases in Subjects With Advanced Cancer

Interventions

DRUG

No Results Yet

NCT07197424 | RECRUITING | NA

100 participants

The Use of Robot Assisted Magnetically Controlled Capsule Endoscopy in Patients With Iron Deficiency Anaemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-05-11
Completion:: 2027-03-31

Conditions

Iron Deficiency Anaemia

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07196631 | COMPLETED | PHASE4

100 participants

Comparison of Liposomal Bupivacaine Versus Ropivacaine in Alleviating Rebound Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-09-20
Completion:: 2026-01-01

Conditions

Rebound Pain
Liposomal Bupivacaine

Interventions

DRUG

No Results Yet

NCT07194993 | RECRUITING | NA

18 participants

PKU Protein Requirements

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-02-16
Completion:: 2027-08-31

Conditions

PKU

Interventions

OTHER

No Results Yet

NCT07193212 | RECRUITING | NA

20 participants

How Osteopathic Treatment Affects the Leg and Foot in People With Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-11-05
Completion:: 2026-09-30

Conditions

Chronic Low Back Pain (CLBP)

Interventions

OTHER

No Results Yet

NCT07192705 | RECRUITING

80 participants

Health Impact of Non-Tuberculous Mycobacteria Pulmonary Disease (NTM-PD)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-14
Start Date:: 2025-08-14
Completion:: 2026-06-01

Conditions

Non-Tuberculous Mycobacteria Pulmonary Disease
Bronchiectasis

No Results Yet

NCT07184944 | RECRUITING | PHASE3

751 participants

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-14
Start Date:: 2026-01-22
Completion:: 2029-08-13

Conditions

Crohn's Disease

Interventions

DRUG

No Results Yet