Clinical Trials

NCT05734157 | COMPLETED | NA

75 participants

CVT-SFA First in Human Trial for Treatment of Superficial Femoral Artery or Proximal Popliteal Artery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2022-02-17
Completion:: 2023-09-11

Conditions

Femoral Artery Stenosis
Popliteal Artery Stenosis
Femoral Artery Occlusion
Popliteal Artery Occlusion

Interventions

DEVICE

Results Available

NCT05731076 | ACTIVE_NOT_RECRUITING | NA

104 participants

Self-Management Support for Lung Cancer Patients With Cachexia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-01-20
Completion:: 2026-12-31

Conditions

Cachexia-Anorexia Syndrome
Lung Neoplasm Malignant

Interventions

BEHAVIORAL

No Results Yet

NCT05724108 | ACTIVE_NOT_RECRUITING | PHASE2

94 participants

Testing the Effectiveness of an Anti-cancer Drug, Triapine, When Used With Targeted Radiation-based Treatment (Lutetium Lu 177 Dotatate), Compared to Lutetium Lu 177 Dotatate Alone for Metastatic Neuroendocrine Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-08-30
Completion:: 2026-12-09

Conditions

Metastatic Neuroendocrine Tumor

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05720806 | COMPLETED | NA

49 participants

Weight Bearing Status Post-hip Arthroscopy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-05-01
Completion:: 2025-12-05

Conditions

Hip Impingement Syndrome
Acetabular Labral Tear

Interventions

OTHER

No Results Yet

NCT05712317 | COMPLETED | NA

43 participants

The Effectiveness of an Exergame-based Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-03-01
Completion:: 2025-01-01

Conditions

Blood Pressure
Physical Inactivity

Interventions

BEHAVIORAL

No Results Yet

NCT05711394 | RECRUITING | PHASE3

450 participants

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-05-01
Completion:: 2028-03-31

Conditions

Episodic Migraine

Interventions

DRUG

No Results Yet

NCT05691517 | RECRUITING | PHASE1

35 participants

Testing How the Body Responds to the Drug CBX-12 in Patients With Advanced Solid Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2024-06-12
Completion:: 2026-10-15

Conditions

Advanced Malignant Solid Neoplasm
Metastatic Malignant Solid Neoplasm

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05691504 | ACTIVE_NOT_RECRUITING | PHASE1

42 participants

Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-09-14
Completion:: 2027-02-01

Conditions

Advanced Endometrial Carcinoma
Metastatic Endometrial Carcinoma
Metastatic Fallopian Tube Carcinoma
Metastatic Platinum-Resistant Ovarian Carcinoma
Metastatic Primary Peritoneal Carcinoma
Recurrent Endometrial Carcinoma
Recurrent Fallopian Tube Carcinoma
Recurrent Platinum-Resistant Ovarian Carcinoma
Recurrent Primary Peritoneal Carcinoma
Stage III Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05691491 | RECRUITING | PHASE1/PHASE2

58 participants

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-09-28
Completion:: 2027-03-01

Conditions

Advanced Malignant Solid Neoplasm
Advanced Microsatellite Stable Colorectal Carcinoma
Hematopoietic and Lymphatic System Neoplasm
Metastatic Malignant Solid Neoplasm
Metastatic Microsatellite Stable Colorectal Carcinoma
Stage III Colorectal Cancer AJCC v8
Stage IV Colorectal Cancer AJCC v8

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05690633 | COMPLETED | NA

100 participants

Feasibility of Obtaining Pulse Oximetry Readings From the Oropharynx

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2024-01-09
Completion:: 2025-01-27

Conditions

Surgery
Arterial Catheterization, Peripheral

Interventions

DEVICE

Results Available

NCT05690386 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

A Trial to Investigate Different Doses of Lonapegsomatropin Compared to Somatropin in Individuals With Turner Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-02-15
Completion:: 2024-10-18

Conditions

Turner Syndrome

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT05689190 | TERMINATED

29 participants

Non-invasive Flow Measurements in Patients With Lower Extremity Arterial Disease (LEAD)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-04-25
Completion:: 2026-02-25

Conditions

Lower Extremity Arterial Disease

No Results Yet

NCT05687136 | RECRUITING | PHASE1

66 participants

Testing the Combination of Two Anti-cancer Drugs, Peposertib (M3814) and Tuvusertib (M1774) for Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2024-06-07
Completion:: 2026-08-31

Conditions

Advanced Malignant Solid Neoplasm
Metastatic Malignant Solid Neoplasm
Unresectable Malignant Solid Neoplasm

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05687123 | RECRUITING | PHASE1

24 participants

Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2024-08-14
Completion:: 2026-12-14

Conditions

Metastatic Pancreatic Neuroendocrine Tumor
Pancreatic Neoplasm
Stage III Pancreatic Neuroendocrine Tumor AJCC v8
Stage IV Pancreatic Neuroendocrine Tumor AJCC v8
Unresectable Pancreatic Neuroendocrine Tumor

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05687110 | RECRUITING | PHASE1

43 participants

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-07-06
Completion:: 2026-08-01

Conditions

Metastatic Malignant Solid Neoplasm
Unresectable Malignant Solid Neoplasm

Interventions

PROCEDURE
BIOLOGICAL

No Results Yet

NCT05677971 | RECRUITING | PHASE3

160 participants

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-03-06
Completion:: 2029-01-17

Conditions

Alpha1-Antitrypsin Deficiency

Interventions

DRUG
OTHER

No Results Yet

NCT05673460 | COMPLETED | PHASE1

7 participants

A Clinical Study of Nemtabrutinib in Japanese Participants With Hematological Malignancies (MK-1026-002)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-02-13
Completion:: 2025-04-28

Conditions

Mature B-cell Neoplasms

Interventions

DRUG

Results Available

NCT05673200 | RECRUITING | PHASE1

32 participants

Testing the Addition of an Anti-cancer Drug, ASTX727 (Cedazuridine, Decitabine), to Chemotherapy (Paclitaxel) and Immunotherapy (Pembrolizumab) for Metastatic Triple-Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-09-25
Completion:: 2027-02-23

Conditions

Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Metastatic Triple-Negative Breast Carcinoma
Unresectable Triple-Negative Breast Carcinoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT05671692 | SUSPENDED | PHASE2

108 participants

Novel Intervention for Chronic Complex TBI in OEF/OIF/OND Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2024-09-06
Completion:: 2026-08-30

Conditions

Traumatic Brain Injury
TBI

Interventions

DRUG

No Results Yet

NCT05669664 | ACTIVE_NOT_RECRUITING | PHASE2

21 participants

Testing the Anti-cancer Drug Darolutamide in Patients With Testosterone-Driven Salivary Gland Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-07-20
Completion:: 2027-04-11

Conditions

Locally Advanced Salivary Gland Carcinoma
Metastatic Salivary Gland Carcinoma
Recurrent Salivary Gland Carcinoma
Unresectable Salivary Gland Carcinoma

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05656027 | COMPLETED | PHASE3

469 participants

Phase 3 Evaluation of the Safety and Efficacy of LNZ100 & LNZ101 for the Treatment of Presbyopia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2022-12-19
Completion:: 2023-12-15

Conditions

Presbyopia
Refractive Error
Eye Diseases
Near Vision

Interventions

DRUG

Results Available

NCT05642416 | COMPLETED | PHASE4

240 participants

Intermittent Bolus vs Continuous Infusion Via ESP Catheters RCT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2022-10-18
Completion:: 2024-12-23

Conditions

Post Operative Pain

Interventions

DRUG

Results Available

NCT05638295 | ACTIVE_NOT_RECRUITING | PHASE2

105 participants

Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2024-08-01
Completion:: 2028-12-31

Conditions

Advanced Malignant Solid Neoplasm
Metastatic Malignant Solid Neoplasm

Interventions

PROCEDURE
BIOLOGICAL
DRUG

No Results Yet

NCT05637203 | ACTIVE_NOT_RECRUITING | PHASE3

100 participants

Study About Group and Phone Follow-Up After a Crisis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2024-04-18
Completion:: 2026-02-28

Conditions

Suicide
Crisis; Emotional

Interventions

BEHAVIORAL

No Results Yet

NCT05630794 | RECRUITING | PHASE1

36 participants

Testing for Safety and Colorectal Cancer Preventive Effects of ONC201

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2025-10-06
Completion:: 2027-05-01

Conditions

Colorectal Adenomatous Polyp
Colorectal Carcinoma
Familial Adenomatous Polyposis
Multiple Adenomatous Polyps

Interventions

PROCEDURE
DRUG
OTHER

No Results Yet

NCT05628246 | COMPLETED | NA

193 participants

Telemedicine Improves Pain-related Disabilities in Following up Cancer Pain Outpatient

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-01-19
Completion:: 2026-01-31

Conditions

Pain, Chronic
Cancer Pain

Interventions

OTHER

No Results Yet

NCT05627245 | ACTIVE_NOT_RECRUITING | PHASE1

48 participants

Testing the Safety of the Anti-cancer Drugs Tazemetostat and Belinostat in Patients With Lymphomas That Have Resisted Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-03-01
Completion:: 2026-09-01

Conditions

Recurrent B-Cell Non-Hodgkin Lymphoma
Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
Recurrent Follicular Lymphoma
Recurrent Non-Hodgkin Lymphoma
Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
Recurrent T-Cell Non-Hodgkin Lymphoma
Recurrent Transformed Non-Hodgkin Lymphoma
Refractory B-Cell Non-Hodgkin Lymphoma
Refractory Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
Refractory Follicular Lymphoma
Refractory Non-Hodgkin Lymphoma
Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
Refractory T-Cell Non-Hodgkin Lymphoma
Refractory Transformed Non-Hodgkin Lymphoma

Interventions

PROCEDURE
OTHER
DRUG

No Results Yet

NCT05617742 | COMPLETED | NA

58 participants

Comparison of 68Ga-FAPI-46 PET and 18F-FDG PET in Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2022-12-01
Completion:: 2026-01-31

Conditions

Lung Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05617014 | ENROLLING_BY_INVITATION

1500 participants

Alzheimer's Disease Neuroimaging Initiative 4

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-06-09
Completion:: 2027-07-31

Conditions

Dementia
Mild Cognitive Impairment
Alzheimer Disease

Interventions

RADIATION

No Results Yet

NCT05613218 | COMPLETED | PHASE2/PHASE3

122 participants

Oxygen Targets in Acute Heart Failure With Pulmonary Congestion

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2024-02-01
Completion:: 2026-02-02

Conditions

Acute Heart Failure
Pulmonary Congestion
Hypoxemia

Interventions

DRUG

No Results Yet

NCT05602194 | ACTIVE_NOT_RECRUITING | PHASE3

440 participants

Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-08-14
Completion:: 2028-06-30

Conditions

B Acute Lymphoblastic Leukemia
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
B Acute Lymphoblastic Leukemia, BCR-ABL1-Like
Lymphoblastic Lymphoma
Mixed Phenotype Acute Leukemia
T Acute Lymphoblastic Leukemia

Interventions

PROCEDURE
DRUG
DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT05600894 | ACTIVE_NOT_RECRUITING | PHASE2

132 participants

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-06-27
Completion:: 2026-08-31

Conditions

Chronic Myelomonocytic Leukemia
Myelodysplastic Syndrome
Myelodysplastic Syndrome With Excess Blasts
Myelodysplastic/Myeloproliferative Neoplasm
Myeloproliferative Neoplasm

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05574361 | ACTIVE_NOT_RECRUITING | NA

120 participants

Continued Access Study to Evaluate Performance of the Organ Recovery Systems _LifePort® Liver Transporter System, a Machine Perfusion System, for Liver Transplant (PILOT™_CA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2022-09-19
Completion:: 2025-09-23

Conditions

Liver Transplantation

Interventions

DEVICE

No Results Yet

NCT05564403 | ACTIVE_NOT_RECRUITING | PHASE2

66 participants

Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2024-02-09
Completion:: 2026-10-01

Conditions

Advanced Biliary Tract Carcinoma
Advanced Gallbladder Carcinoma
Advanced Intrahepatic Cholangiocarcinoma
Recurrent Biliary Tract Carcinoma
Recurrent Gallbladder Carcinoma
Recurrent Intrahepatic Cholangiocarcinoma
Stage III Distal Bile Duct Cancer AJCC v8
Stage III Gallbladder Cancer AJCC v8
Stage III Hilar Cholangiocarcinoma AJCC v8
Stage III Intrahepatic Cholangiocarcinoma AJCC v8
Stage IV Distal Bile Duct Cancer AJCC v8
Stage IV Gallbladder Cancer AJCC v8
Stage IV Hilar Cholangiocarcinoma AJCC v8
Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
Unresectable Biliary Tract Carcinoma
Unresectable Gallbladder Carcinoma
Unresectable Intrahepatic Cholangiocarcinoma

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05554367 | ACTIVE_NOT_RECRUITING | PHASE2

199 participants

Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-12-13
Completion:: 2026-08-26

Conditions

Exocrine Pancreas Carcinoma
Malignant Solid Neoplasm
Ovarian Low Grade Serous Adenocarcinoma
Stage IV Ovarian Cancer AJCC v8
Stage IV Pancreatic Cancer AJCC v8

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05546866 | ACTIVE_NOT_RECRUITING | PHASE2

51 participants

Study to Assess the Efficacy and Safety of Adjuvant Osimertinib in NSCLC With Uncommon EGFRm

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-02-09
Completion:: 2029-06-30

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05538897 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

96 participants

Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-03-31
Completion:: 2027-01-31

Conditions

FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma
FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma
Metastatic Endometrial Endometrioid Adenocarcinoma
Recurrent Endometrial Endometrioid Adenocarcinoma

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05533242 | ACTIVE_NOT_RECRUITING | PHASE1

15 participants

Radioimmunotherapy With Lu-177 Labeled 6A10 Fab-fragments in Patients With Glioblastoma After Standard Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2024-01-22
Completion:: 2026-10-31

Conditions

Glioblastom WHO Grade 4

Interventions

DRUG

No Results Yet

NCT05515341 | COMPLETED

73 participants

A DirEct to PatieNt Study in Chronic Pain

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-13
Start Date:: 2023-01-10
Completion:: 2026-05-11

Conditions

Chronic Pain

Interventions

DEVICE

No Results Yet

NCT05514990 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

10 participants

Bortezomib and Pembrolizumab With or Without Pelareorep for the Treatment of Relapsed or Refractory Multiple Myeloma, AMBUSH Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-13
Start Date:: 2022-10-07
Completion:: 2026-12-31

Conditions

Recurrent Plasma Cell Myeloma
Refractory Plasma Cell Myeloma

Interventions

DRUG
BIOLOGICAL

No Results Yet