Clinical Trials

NCT05978362 | RECRUITING | NA

86 participants

Value of Capsular Repair for Latarjet

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-10-11

Completion:

2037-12-31

Conditions

• Shoulder Pain

Interventions

• PROCEDURE

No Results Yet

NCT05963503 | COMPLETED

62 participants

Predictors of Health Literacy in Adults With Cystic Fibrosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-13

Start Date:

2023-08-15

Completion:

2024-08-15

Conditions

• Cystic Fibrosis

Interventions

• OTHER

No Results Yet

NCT05947500 | ACTIVE_NOT_RECRUITING | PHASE2

50 participants

Testing the Combination of Two Anticancer Drugs M1774 (Tuvusertib) and Avelumab to Evaluate Their Safety and Effectiveness in Treating Merkel Cell Skin Cancer, MATRiX Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2024-05-21

Completion:

2028-01-01

Conditions

• Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8
• Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8
• Locally Advanced Merkel Cell Carcinoma
• Metastatic Merkel Cell Carcinoma
• Refractory Merkel Cell Carcinoma
• Unresectable Merkel Cell Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT05941520 | RECRUITING | PHASE2

80 participants

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2024-08-23

Completion:

2027-08-23

Conditions

• Breast Atypical Hyperplasia
• Breast Carcinoma
• Breast Ductal Carcinoma In Situ
• Breast Lobular Carcinoma In Situ

Interventions

• DRUG
• PROCEDURE
• OTHER

No Results Yet

NCT05934305 | RECRUITING | NA

256 participants

Mitigating the Impact of Stigma and Shame Among People Living With HIV and Substance Use Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2025-03-12

Completion:

2028-06-30

Conditions

• Hiv
• Substance Use Disorders

Interventions

• BEHAVIORAL

No Results Yet

NCT05925049 | ACTIVE_NOT_RECRUITING

400 participants

A Study Utilising Data From European Union (EU) National Multiple Sclerosis (MS) Registries to Assess the Incidence of Anti-Natalizumab Antibody Among Participants Who Receive Subcutaneous Administration of Natalizumab for Treatment of Relapsing-remitting Multiple Sclerosis (RRMS)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-13

Start Date:

2023-06-30

Completion:

2026-10-31

Conditions

• Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT05896839 | RECRUITING | PHASE1/PHASE2

16 participants

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2024-07-24

Completion:

2027-01-31

Conditions

• Clinical Stage III Cutaneous Melanoma AJCC v8
• Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8
• Clinical Stage IV Cutaneous Melanoma AJCC v8
• Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8
• Metastatic Basal Cell Carcinoma
• Metastatic Carcinoma in the Skin
• Metastatic Melanoma
• Metastatic Merkel Cell Carcinoma
• Metastatic Skin Squamous Cell Carcinoma
• Unresectable Basal Cell Carcinoma
• Unresectable Melanoma
• Unresectable Merkel Cell Carcinoma
• Unresectable Skin Squamous Cell Carcinoma

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG

No Results Yet

NCT05886036 | RECRUITING | PHASE2

70 participants

Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma, NORM Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2024-01-23

Completion:

2026-10-31

Conditions

• Nodular Lymphocyte Predominant B-Cell Lymphoma
• Recurrent Nodular Lymphocyte Predominant B-Cell Lymphoma
• Refractory Nodular Lymphocyte Predominant B-Cell Lymphoma

Interventions

• PROCEDURE
• OTHER
• BIOLOGICAL

No Results Yet

NCT05877599 | RECRUITING | PHASE1

45 participants

A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-07-12

Completion:

2029-07-31

Conditions

• Non-small Cell Lung Cancer
• Head and Neck Squamous Cell Carcinoma
• Colorectal Carcinoma
• Pancreatic Adenocarcinoma
• Breast Cancer
• Other Solid Tumors
• Ovarian Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT05866627 | COMPLETED | PHASE1

32 participants

A Study to Assess the Effect of Famotidine on the Drug Levels of Afimetoran in Healthy Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-07-04

Completion:

2023-09-29

Conditions

• Healthy Volunteers

Interventions

• DRUG

No Results Yet

NCT05864534 | RECRUITING | PHASE2

25 participants

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2024-01-19

Completion:

2031-07-31

Conditions

• Gliosarcoma
• Newly Diagnosed Glioblastoma
• Glioblastoma, Isocitric Dehydrogenase (IDH)-Wildtype
• Glioblastoma Multiforme

Interventions

• DRUG
• DEVICE

No Results Yet

NCT05859334 | RECRUITING | PHASE2

30 participants

Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2024-01-04

Completion:

2026-10-23

Conditions

• Recurrent Glioma
• Recurrent WHO Grade 2 Glioma
• Recurrent WHO Grade 3 Glioma
• Recurrent WHO Grade 4 Glioma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05854160 | RECRUITING | NA

30 participants

Stimulation-Induced Changes in Fronto-Limbic Network

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-03-01

Completion:

2026-02-28

Conditions

• Epilepsy
• Mental Disorders

Interventions

• PROCEDURE

No Results Yet

NCT05842681 | RECRUITING | NA

1000 participants

Azithromycin in the Management of Patients With Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-06-01

Completion:

2027-01-01

Conditions

• Idiopathic Pulmonary Fibrosis

Interventions

• DRUG

No Results Yet

NCT05834413 | RECRUITING | NA

367 participants

Clinical Study on the Prevention of Driver Gene Negative Ib-IIIb Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint Inhibitors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-05-01

Completion:

2027-06-30

Conditions

• Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05831891 | ACTIVE_NOT_RECRUITING | PHASE2

39 participants

Fruquintinib Plus Serplulimab as First-Line Therapy for Metastatic Non-Clear Cell Renal Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-05-01

Completion:

2026-07-31

Conditions

• Non-clear Renal Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT05831878 | RECRUITING | NA

36 participants

RC48-ADC in HER2-low Advanced Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-05-04

Completion:

2026-12-31

Conditions

• Advanced Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05828511 | RECRUITING | PHASE1/PHASE2

149 participants

A Window of Opportunity Trial to Learn if Linvoseltamab is Safe and Well Tolerated, and How Well it Works in Adult Participants With Recently Diagnosed Multiple Myeloma Who Have Not Already Received Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-12-19

Completion:

2035-11-02

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05828082 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Testing the Effect of M1774 on Hard-to-Treat Refractory SPOP-mutant Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-10-16

Completion:

2027-01-01

Conditions

• Castration-Resistant Prostate Carcinoma
• Metastatic Castration-Resistant Prostate Carcinoma
• Refractory Prostate Carcinoma
• Stage IVB Prostate Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05826457 | ENROLLING_BY_INVITATION

500 participants

North American Prodromal Synucleinopathy Consortium Stage 2

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-13

Start Date:

2022-08-12

Completion:

2027-05-01

Conditions

• REM Sleep Behavior Disorder
• Parkinson Disease
• Lewy Body Dementia
• Dementia With Lewy Bodies
• Multiple System Atrophy
• REM Sleep Parasomnias

No Results Yet

NCT05819359 | ACTIVE_NOT_RECRUITING | PHASE2

237 participants

Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-03-31

Completion:

2026-04-02

Conditions

• Parkinson's Disease

Interventions

• DRUG

No Results Yet

NCT05812924 | ACTIVE_NOT_RECRUITING | PHASE2

18 participants

A Novel Therapy for Breast Cancer Survivors With Genitourinary Syndrome of Menopause

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-09-26

Completion:

2026-09-30

Conditions

• Breast Cancer
• Genitourinary Syndrome of Menopause

Interventions

• BIOLOGICAL

No Results Yet

NCT05811364 | RECRUITING | NA

244 participants

The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-10-17

Completion:

2028-03-30

Conditions

• Aortoiliac Occlusive Disease
• Peripheral Arterial Disease

Interventions

• DEVICE

No Results Yet

NCT05804240 | COMPLETED

67 participants

TEE 3D RV Assessment for SAVR, Mini AVR, and TAVR

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-13

Start Date:

2023-04-01

Completion:

2025-06-30

Conditions

• Right Ventricular Dysfunction

Interventions

• DIAGNOSTIC_TEST

Results Available

NCT05803382 | RECRUITING | PHASE1

30 participants

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-11-08

Completion:

2026-06-30

Conditions

• Metastatic Colorectal Carcinoma
• Metastatic Malignant Solid Neoplasm
• Stage IV Colorectal Cancer AJCC v8
• Unresectable Colorectal Carcinoma
• Unresectable Malignant Solid Neoplasm

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05799573 | COMPLETED

50 participants

CT Scan Sizing for Perceval Sutureless Valve

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-13

Start Date:

2022-12-01

Completion:

2026-04-01

Conditions

• Aortic Valve Regurgitation

No Results Yet

NCT05794880 | RECRUITING | NA

40 participants

MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-05-01

Completion:

2027-05-31

Conditions

• Leukemia
• Acute Myeloid Leukemia in Remission
• Myelodysplasia
• Acute Lymphoblastic Leukemia in Remission
• Chronic Myelogenous Leukemia - Chronic Phase
• Chronic Myelogenous Leukemia, Accelerated Phase
• Chronic Myelogenous Leukemia With Crisis of Blast Cells
• Biphenotypic Acute Leukemia
• Lymphoblastic Lymphoma
• Burkitt Lymphoma
• Burkitt Leukemia
• Lymphoma After Relapse
• Other Malignant Hematologic Diseases in Remission

Interventions

• DEVICE

No Results Yet

NCT05791149 | RECRUITING | NA

60 participants

Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2022-03-03

Completion:

2027-04-30

Conditions

• Oral Squamous Cell Carcinoma
• Maxillo-facial Surgery
• Biomarkers
• Saliva
• DNA Methylation
• Epigenetics

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05785156 | RECRUITING

129 participants

Diagnostic and Prognostic Value of New Quick Tests of Action Slowing in Stroke and in Cognitive Neurodegenerative Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-13

Start Date:

2021-07-16

Completion:

2027-07-16

Conditions

• Stroke
• Action Speed
• Dementia Mild Cognitive Impairment
• Alzheimer Disease

Interventions

• OTHER

No Results Yet

NCT05783869 | RECRUITING

30 participants

Study of Bronchiectasis and Associated Cardiovascular Comorbidities

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-13

Start Date:

2023-03-25

Completion:

2026-09-01

Conditions

• Bronchiectasis

Interventions

• DEVICE

No Results Yet

NCT05775289 | ACTIVE_NOT_RECRUITING | PHASE2

182 participants

A Study of Tobemstomig Plus Platinum-Based Chemotherapy vs Pembrolizumab Plus Platinum-Based Chemotherapy in Participants With Previously Untreated Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-03-15

Completion:

2024-06-20

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT05766072 | COMPLETED | NA

217 participants

Early Intervention Coping Kids (TIM) Follow up Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-03-13

Completion:

2024-02-29

Conditions

• Anxiety Disorders
• Depression

Interventions

• OTHER

No Results Yet

NCT05765071 | RECRUITING | NA

50 participants

Treatment of Lower Leg Anterolateral Chronic Exertional Compartment Syndrome With Intra-muscular Botulinum Injections.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2025-07-17

Completion:

2028-06-30

Conditions

• Chronic Exertional Compartment Syndrome

Interventions

• BIOLOGICAL

No Results Yet

NCT05762887 | COMPLETED | NA

141 participants

Clinical Evaluation of the Antidepressant Effect of the Use of Probiotics in Bipolar Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-01-09

Completion:

2025-03-01

Conditions

• Bipolar Disorder

Interventions

• OTHER

No Results Yet

NCT05762055 | ENROLLING_BY_INVITATION | NA

200 participants

Prospective Comparative Analysis of ACDF vs Fusion Interbody Cages With nanoLOCK Osseointegrative Technology

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2024-02-05

Completion:

2026-05-31

Conditions

• Cervical Radiculopathy
• Cervical Myelopathy

Interventions

• DEVICE

No Results Yet

NCT05758142 | TERMINATED | NA

25 participants

Potassium Intake-response Trial to Control Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-03-29

Completion:

2024-05-03

Conditions

• Blood Pressure

Interventions

• DIETARY_SUPPLEMENT
• OTHER

Results Available

NCT05753189 | COMPLETED | PHASE3

362 participants

Phase 3 Safety Study of LNZ100 and LNZ101 for the Treatment of Presbyopia Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2023-02-21

Completion:

2024-02-09

Conditions

• Presbyopia
• Near Vision
• Refractive Error
• Eye Diseases

Interventions

• DRUG

Results Available

NCT05751408 | RECRUITING

40 participants

Technical Evaluation of Commercial IMUs Within Clinical Gait Analysis

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-13

Start Date:

2023-01-25

Completion:

2028-12-31

Conditions

• Gait Analysis

Interventions

• PROCEDURE

No Results Yet

NCT05738824 | RECRUITING

500 participants

Natural History of Inflammatory Muscle Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-13

Start Date:

2023-06-01

Completion:

2032-02-25

Conditions

• Inflammation In Skeletal Muscle

No Results Yet

NCT05737290 | COMPLETED | NA

12 participants

Effects of Clear Aligners Versus Fixed Appliances on Occlusion After Treatment of Mild Anterior Crowding

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-13

Start Date:

2024-05-01

Completion:

2026-03-01

Conditions

• Occlusion

Interventions

• DEVICE

No Results Yet