Clinical Trials

NCT05889299 | COMPLETED | PHASE1

15 participants

Study of the Safety and Efficacy of OMS906 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2022-12-09
Completion:: 2025-11-03

Conditions

Paroxysmal Nocturnal Hemoglobinuria

Interventions

BIOLOGICAL

No Results Yet

NCT05887778 | COMPLETED | PHASE4

90 participants

Dexamethasone in Supraclavicular Brachial Plexus Block for Anesthesia After Pediatric Hand/Wrist Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-09-18
Completion:: 2026-03-30

Conditions

Wrist Disease
Hand Injuries and Disorders

Interventions

DRUG

No Results Yet

NCT05880290 | COMPLETED | NA

547 participants

Performance of the Gynaecological Examination in the Lateral Decubitus Position

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-07-10
Completion:: 2026-04-11

Conditions

Medical Care

Interventions

PROCEDURE

No Results Yet

NCT05874102 | ENROLLING_BY_INVITATION | NA

40 participants

The Effect of Body Position on Oropharyngeal Swallow Function in Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-12-20
Completion:: 2024-12-20

Conditions

Aspiration

Interventions

OTHER

No Results Yet

NCT05849610 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Teclistamab-Daratumumab and Talquestamab-Daratumumab in Newly Diagnosed High-risk Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-09-21
Completion:: 2026-03-03

Conditions

High-Risk de Novo Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05838248 | TERMINATED | NA

23 participants

Complex and Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-01-24
Completion:: 2025-10-31

Conditions

Appendicitis

Interventions

OTHER

No Results Yet

NCT05835986 | RECRUITING | PHASE1

70 participants

A First-in-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7507062 in Participants With Systemic Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-12-18
Completion:: 2027-11-30

Conditions

Systemic Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT05828901 | TERMINATED

23 participants

Predicting Disease Activity and Rebound Risk in MS Patients Treated With Sphingosine-1-phosphate Receptor Modulators (S1PRM)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-03-27
Completion:: 2025-10-16

Conditions

Multiple Sclerosis

Interventions

OTHER

No Results Yet

NCT05826379 | ENROLLING_BY_INVITATION | NA

200 participants

Daily Goal Setting to Increase Everyday Physical Activity and Promote Cognitive Health in Midlife

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2024-03-20
Completion:: 2027-05-31

Conditions

Physical Inactivity
Walking
Cognitive Health
Self-regulation
Overweight and Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT05820516 | RECRUITING

100 participants

Patients With Severe TrIcuspid Regurgitation After triCvALve System Implantation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-11
Start Date:: 2025-02-01
Completion:: 2026-12-31

Conditions

Severe Tricuspid Valve Regurgitation

Interventions

DEVICE

No Results Yet

NCT05809752 | ACTIVE_NOT_RECRUITING | PHASE1

15 participants

A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-08-22
Completion:: 2026-08-31

Conditions

Leptomeningeal Disease
Triple Negative Breast Cancer
HER2-positive Breast Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT05797610 | RECRUITING | PHASE3

428 participants

A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-08-08
Completion:: 2026-08-31

Conditions

Primary IgA Nephropathy

Interventions

DRUG

No Results Yet

NCT05795140 | RECRUITING | PHASE3

65 participants

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2024-05-08
Completion:: 2032-07-16

Conditions

Atypical Hemolytic Uremic Syndrome

Interventions

DRUG

No Results Yet

NCT05780372 | ACTIVE_NOT_RECRUITING | PHASE3

474 participants

Reduced Volume of Neck Prophylactic Irradiation in Nasopharyngeal Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-08-08
Completion:: 2025-04-01

Conditions

Nasopharyngeal Carcinoma
Radiotherapy; Complications

Interventions

RADIATION
DRUG

No Results Yet

NCT05773157 | WITHDRAWN | NA

0 participants

Evaluation of SNAP-Ed Online Modules to Improve Responsive Feeding Practices of Caregivers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2024-06-01
Completion:: 2026-12-31

Conditions

Feeding Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT05732207 | RECRUITING | NA

122 participants

Cerebellar Involvement in Alcohol Use Disorder (AUD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-10-12
Completion:: 2027-04-30

Conditions

Alcohol Use Disorder

Interventions

PROCEDURE

No Results Yet

NCT05731375 | COMPLETED

12 participants

Mitochondrial dysfUnction: a Key Player in Doxorubicin-induced Skeletal and Cardiac muscLE Damage

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-12-28
Completion:: 2026-03-20

Conditions

Doxorubicin Induced Cardiomyopathy
Chemotherapeutic Toxicity
Anthracyclines

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05705258 | ACTIVE_NOT_RECRUITING

75 participants

A Study to Collect Data on the Use of Eylea in Babies Born Too Early Who Have a Condition of the Eye Where Blood Vessels Grow Abnormally in the Retina (Retinopathy of Prematurity)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-03-27
Completion:: 2026-02-06

Conditions

Retinopathy of Prematurity
Newborns
Infants

Interventions

DRUG

No Results Yet

NCT05694871 | ACTIVE_NOT_RECRUITING | PHASE2

77 participants

Testing the Addition of Cemiplimab to Palbociclib for the Treatment of Advanced Dedifferentiated Liposarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-06-07
Completion:: 2027-05-31

Conditions

Advanced Dedifferentiated Liposarcoma
Locally Advanced Dedifferentiated Liposarcoma
Metastatic Dedifferentiated Liposarcoma
Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
Unresectable Dedifferentiated Liposarcoma

Interventions

DRUG
BIOLOGICAL
PROCEDURE
OTHER

No Results Yet

NCT05689021 | ACTIVE_NOT_RECRUITING | PHASE2

8 participants

CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2024-03-05
Completion:: 2026-07-31

Conditions

Castration-Resistant Prostate Carcinoma
Metastatic Prostate Adenocarcinoma
Stage IVB Prostate Cancer AJCC v8

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05688475 | ACTIVE_NOT_RECRUITING | PHASE1

12 participants

A Rollover Study of CC-122

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-04-11
Completion:: 2026-10-31

Conditions

Non-Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT05680012 | RECRUITING | NA

220 participants

Tissue Destruction and Healing in Celiac Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-07-14
Completion:: 2027-06-30

Conditions

Celiac Disease

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05672251 | RECRUITING | PHASE2

36 participants

Loncastuximab Tesirine and Mosunetuzumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2024-01-02
Completion:: 2027-03-23

Conditions

Recurrent Diffuse Large B-Cell Lymphoma
Recurrent Grade 3b Follicular Lymphoma
Recurrent High Grade B-Cell Lymphoma
Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma
Recurrent Transformed Chronic Lymphocytic Leukemia
Recurrent Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
Refractory Diffuse Large B-Cell Lymphoma
Refractory Grade 3b Follicular Lymphoma
Refractory High Grade B-Cell Lymphoma
Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma
Refractory Transformed Chronic Lymphocytic Leukemia
Refractory Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma

Interventions

PROCEDURE
BIOLOGICAL

No Results Yet

NCT05669989 | ACTIVE_NOT_RECRUITING | PHASE2

70 participants

International Treatment-extension Study in Adult Participants With Multiple Myeloma and Who Have Derived Clinical Benefit From Isatuximab

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-04-05
Completion:: 2026-11-30

Conditions

Plasma Cell Myeloma

Interventions

DRUG

No Results Yet

NCT05667298 | ACTIVE_NOT_RECRUITING | PHASE1

11 participants

Organ-Preserving Endoscopic Resection & Adjuvant RADIO-immuno-chemotherapy for Esophageal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-03-01
Completion:: 2025-06-20

Conditions

Esophageal Cancer

Interventions

DRUG

No Results Yet

NCT05661955 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

113 participants

A Study to Investigate the Antitumor Activity, Safety, Tolerability, and Pharmacokinetics of BGB-A445 in Combination With Tislelizumab in Participants With Select Advanced Solid Tumors.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-01-09
Completion:: 2025-05-27

Conditions

Urothelial Carcinoma
Renal Cell Carcinoma
Melanoma
Non-mucosal Melanoma

Interventions

DRUG

No Results Yet

NCT05654467 | RECRUITING | PHASE2

1532 participants

Study of a Novel Type 3 Oral Poliomyelitis Vaccine in Panama

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-12-05
Completion:: 2027-03-20

Conditions

Poliomyelitis

Interventions

BIOLOGICAL

No Results Yet

NCT05651295 | RECRUITING | NA

390 participants

A Precision Medicine Approach to Target Engagement for Emotion Regulation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-09-29
Completion:: 2026-12-31

Conditions

Emotional Regulation
Depression
Anxiety
Borderline Personality Disorder
Obsessive-Compulsive Disorder
Posttraumatic Stress Disorder
Eating Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT05647122 | RECRUITING | PHASE1

403 participants

First in Human Study of AZD9592 in Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2022-12-21
Completion:: 2028-08-02

Conditions

Advanced Solid Tumours
Carcinoma Non-small Cell Lung
Head and Neck Neoplasms
Colorectal Neoplasms

Interventions

DRUG

No Results Yet

NCT05645510 | RECRUITING

75 participants

LIVInG With chrONic Cancer TrEatments (LONGEVITI) Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-11
Start Date:: 2022-11-24
Completion:: 2026-06-09

Conditions

Cancer
Tyrosine Kinase Mutation
Breast Cancer
Melanoma
Multiple Myeloma
Chronic Leukemia
Prostate Cancer
Ovarian Cancer
Colorectal Cancer
Lung Cancer

No Results Yet

NCT05644522 | RECRUITING | NA

36 participants

Nomad P-KAFO Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2024-03-01
Completion:: 2027-12-31

Conditions

Cerebrovascular Accident
Post-polio Syndrome
Spinal Cord Injuries
Multiple Sclerosis
Muscular Dystrophy
Paralysis

Interventions

DEVICE

No Results Yet

NCT05634889 | RECRUITING | NA

1350 participants

The T-REX Trial: Tailored Regional External Beam Radiotherapy in Clinically Node-negative Breast Cancer Patients With 1-2 Sentinel Node Macrometastases.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-03-17
Completion:: 2028-12-31

Conditions

Breast Cancer

Interventions

RADIATION

No Results Yet

NCT05615142 | ACTIVE_NOT_RECRUITING | PHASE1

9 participants

Safety and Tolerability of Low Dose Radiotherapy Concurrent SBRT and PD-1 Inhibitors in Advanced NSCLC.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2021-12-15
Completion:: 2024-04-30

Conditions

NSCLC
Low Dose Radiotherapy
Stereotactic Body Radiotherapy
PD-1 Inhibitor

Interventions

RADIATION
DRUG

No Results Yet

NCT05612750 | RECRUITING | NA

1650 participants

Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-01-01
Completion:: 2029-05-01

Conditions

Pain, Chronic
Lupus
Pelvic Pain

Interventions

BEHAVIORAL

No Results Yet

NCT05609318 | RECRUITING

12 participants

Imaging Intravenous Iron

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-11
Start Date:: 2022-10-29
Completion:: 2026-12-31

Conditions

Iron-deficiency

No Results Yet

NCT05603702 | RECRUITING | PHASE1

24 participants

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-03-17
Completion:: 2027-03-31

Conditions

Chronic Pain
Chronic Pain Syndrome
Chronic Pancreatitis
Hyperalgesia
Opioid Use Disorder
Opioid-Related Disorders
Opioid Dependence
Chronic Abdominal Pain
ERCP
Pancreatic Surgery

Interventions

DRUG

No Results Yet

NCT05586802 | RECRUITING | PHASE3

150 participants

Sex Steroids Balance for Metabolic and Reproductive Health in Klinefelter Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2023-03-21
Completion:: 2027-04-30

Conditions

Klinefelter Syndrome

Interventions

DRUG

No Results Yet

NCT05581004 | RECRUITING | PHASE1

450 participants

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2022-10-20
Completion:: 2028-07-31

Conditions

Locally Advanced or Metastatic Solid Tumors
NSCLC
HNSCC
Melanoma
TNBC
Esophageal Cancer
Gastric Cancer
Cervical Cancer
Colorectal Cancer
Urothelial Carcinoma
Clear Cell RCC
HCC

Interventions

DRUG

No Results Yet

NCT05579678 | RECRUITING

45 participants

APOLLO: Personalized rehAbilitation PrOgram in aLLOgeneic Bone Marrow Transplantation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-11
Start Date:: 2022-11-20
Completion:: 2026-08-31

Conditions

Allogeneic Disease

Interventions

BEHAVIORAL

No Results Yet

NCT05548439 | COMPLETED | PHASE1

103 participants

Safety, Tolerability, and Immunogenicity of Trivalent Coronavirus Vaccine Candidate VBI-2901a

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-11
Start Date:: 2022-10-05
Completion:: 2024-01-16

Conditions

COVID-19
Coronavirus Infections

Interventions

BIOLOGICAL

No Results Yet