Clinical Trials

NCT05538910 | RECRUITING | NA

620 participants

Defining Neurobiological Links Between Substance Use and Mental Illness

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2023-02-02

Completion:

2027-12-30

Conditions

• Major Depressive Disorder
• Substance Use Disorder
• Normal Physiology

Interventions

• OTHER
• DRUG

No Results Yet

NCT05538247 | COMPLETED | EARLY_PHASE1

56 participants

Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2023-04-13

Completion:

2025-12-30

Conditions

• Healthy

Interventions

• DRUG
• DIETARY_SUPPLEMENT

No Results Yet

NCT05528510 | ACTIVE_NOT_RECRUITING | PHASE3

418 participants

A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-09-13

Completion:

2024-04-02

Conditions

• Colitis, Ulcerative

Interventions

• DRUG
• OTHER

Results Available

NCT05514535 | COMPLETED | PHASE3

573 participants

A Research Study to Look Into How Semaglutide, Together With a Lower Dose of Insulin Glargine, Compares to a Higher Dose of Insulin Glargine Alone in People With Type 2 Diabetes (SUSTAIN OPTIMIZE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-08-29

Completion:

2025-03-05

Conditions

• Diabetes Mellitus, Type 2
• Obesity

Interventions

• DRUG

Results Available

NCT05513326 | COMPLETED | NA

51 participants

Effectiveness of a 6-week Specific Rehabilitation Program on Walking Capacity in Patients With Lumbar Spinal Stenosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2023-01-26

Completion:

2025-09-30

Conditions

• Spinal Stenosis

Interventions

• OTHER

No Results Yet

NCT05499637 | RECRUITING | PHASE2

69 participants

[68Ga]Ga-PentixaFor PET/CT in Acute Myocardial Inflammation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2023-01-17

Completion:

2026-12-31

Conditions

• Acute Cellular Graft Rejection
• Cardiac Sarcoidosis
• Myocarditis Due to Drug

Interventions

• DRUG

No Results Yet

NCT05496868 | COMPLETED | PHASE2

66 participants

Add-on Reparixin in Adult Patients With ARDS

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-12-06

Completion:

2025-03-18

Conditions

• Acute Respiratory Distress Syndrome, Adult

Interventions

• DRUG
• OTHER

Results Available

NCT05489822 | TERMINATED

4 participants

PMCF Study to Evaluate the VERTICALE® Cervical System in Spine Surgery According to Its Intended Use.

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-11

Start Date:

2023-01-13

Completion:

2024-11-30

Conditions

• Degenerative Disc Disease (DDD)
• Instabilities
• Trauma
• Deformity

Interventions

• DEVICE

No Results Yet

NCT05486832 | ACTIVE_NOT_RECRUITING | NA

157 participants

TARGET Study: Safety and Performance of the Cardiovalve TR Replacement System

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-12-09

Completion:

2026-03-15

Conditions

• Tricuspid Regurgitation

Interventions

• DEVICE

No Results Yet

NCT05484115 | RECRUITING | NA

300 participants

Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2023-05-26

Completion:

2029-04-30

Conditions

• Aortic Aneurysm, Abdominal

Interventions

• DEVICE

No Results Yet

NCT05470218 | ACTIVE_NOT_RECRUITING | NA

10 participants

Leucine, mTOR and Athero

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-07-12

Completion:

2023-08-14

Conditions

• Atherosclerosis

Interventions

• OTHER

No Results Yet

NCT05468151 | ACTIVE_NOT_RECRUITING | NA

45 participants

Cold Acclimation as a Modulator of Brown Adipose Tissue Function in Adults With Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-07-25

Completion:

2024-12-20

Conditions

• Obesity

Interventions

• OTHER

No Results Yet

NCT05460013 | COMPLETED | NA

100 participants

Impact of Oral Nutritional Supplements on Patients Undergoing Haematopoietic Stem Cell Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-08-01

Completion:

2025-06-15

Conditions

• Haematological Malignancy

Interventions

• DIETARY_SUPPLEMENT

Results Available

NCT05457283 | RECRUITING | PHASE3

100 participants

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-11-08

Completion:

2029-01-28

Conditions

• Chronic Kidney Disease
• Proteinuria
• Children

Interventions

• DRUG

No Results Yet

NCT05456607 | RECRUITING | NA

1200 participants

Digital CBT for Insomnia and Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2023-05-01

Completion:

2027-03-31

Conditions

• Depression
• Insomnia

Interventions

• BEHAVIORAL

No Results Yet

NCT05453500 | ACTIVE_NOT_RECRUITING | PHASE2

32 participants

Chemotherapy (DA-EPOCH+/-R) and Targeted Therapy (Tafasitamab) for the Treatment of Newly-Diagnosed Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2023-03-27

Completion:

2026-04-28

Conditions

• B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

Interventions

• DRUG
• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT05453396 | RECRUITING | PHASE2

20 participants

Loncastuximab Tesirine for the Treatment of Relapsed or Refractory B-Cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2023-08-07

Completion:

2027-12-15

Conditions

• Recurrent B-Cell Non-Hodgkin Lymphoma
• Recurrent Diffuse Large B-Cell Lymphoma
• Recurrent Follicular Lymphoma
• Recurrent Mantle Cell Lymphoma
• Refractory B-Cell Non-Hodgkin Lymphoma
• Refractory Diffuse Large B-Cell Lymphoma
• Refractory Follicular Lymphoma
• Refractory Mantle Cell Lymphoma

Interventions

• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT05452941 | RECRUITING

12500 participants

A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-11

Start Date:

2022-10-27

Completion:

2027-06-04

Conditions

• Pneumonia

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05440643 | COMPLETED | PHASE1/PHASE2

209 participants

Peanut Sublingual Immunotherapy (SLIT)-Tablet for Treatment of Peanut Allergy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-09-07

Completion:

2026-03-10

Conditions

• Peanut Allergy

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT05425316 | COMPLETED

251 participants

Speech in Hepatic Encephalopathy (HE)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-11

Start Date:

2021-10-05

Completion:

2024-07-24

Conditions

• Hepatic Encephalopathy

Interventions

• BEHAVIORAL

No Results Yet

NCT05424172 | RECRUITING | NA

50 participants

Improving Adherence to Spinal Cord Injury Exercise Guidelines Using Smartphone Technology and E-coaching

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-11-02

Completion:

2026-08-31

Conditions

• Spinal Cord Injuries

Interventions

• BEHAVIORAL

No Results Yet

NCT05391529 | COMPLETED

12 participants

Patients Decision Making in Choosing Between Colonic Investigation Alternatives

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-11

Start Date:

2022-05-19

Completion:

2022-08-01

Conditions

• Colonic Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT05379699 | COMPLETED | NA

82 participants

Development and Validation of an Online Independent Training Program for TOR-BSST© Dysphagia Screeners

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-10-01

Completion:

2023-02-15

Conditions

• Dysphagia
• Stroke

Interventions

• OTHER

No Results Yet

NCT05379153 | RECRUITING | PHASE3

250 participants

Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2026-04-21

Completion:

2026-09-30

Conditions

• Anatomic Stage 0 Breast Cancer AJCC v8
• Anatomic Stage I Breast Cancer AJCC v8
• Anatomic Stage IA Breast Cancer AJCC v8
• Anatomic Stage IB Breast Cancer AJCC v8
• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage IIA Breast Cancer AJCC v8
• Anatomic Stage IIB Breast Cancer AJCC v8
• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IIIA Breast Cancer AJCC v8
• Anatomic Stage IIIB Breast Cancer AJCC v8
• Anatomic Stage IIIC Breast Cancer AJCC v8
• Vaginal Atrophy

Interventions

• DEVICE
• OTHER

No Results Yet

NCT05370053 | COMPLETED | NA

450 participants

The Availability of the Enhanced Liver Fibrosis (ELF) Test Affects the Rate of Diagnosis of Nonalcoholic Steatohepatitis (NASH) With Fibrosis in Patients Referred to Hepatology

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2020-09-01

Completion:

2022-12-01

Conditions

• Fatty Liver
• NAFLD

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05357378 | RECRUITING | NA

288 participants

Safety and Effectiveness of the HIT Reverse HRS

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-07-15

Completion:

2026-07-15

Conditions

• Degenerative Joint Disease
• Osteoarthritis, Hip
• Avascular Necrosis of Hip
• Traumatic Arthropathy-Hip

Interventions

• DEVICE

No Results Yet

NCT05349968 | COMPLETED | PHASE1

24 participants

Pharmacokinetics and Efficacy of Multiple Dosing of Lipovirtide for Injection in HIV-infected Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-06-10

Completion:

2023-06-07

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT05348733 | ACTIVE_NOT_RECRUITING

4613 participants

A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-11

Start Date:

2022-06-13

Completion:

2026-10-26

Conditions

• Chronic Kidney Disease
• Type 2 Diabetes Mellitus

Interventions

• DRUG

No Results Yet

NCT05340491 | RECRUITING | PHASE3

212 participants

Chemoradiotherapy Plus Anti-PD1 in Recurrent NPC: A Multicenter, Open-label, Randomised, Controlled, Phase III Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-04-01

Completion:

2026-12-31

Conditions

• Nasopharyngeal Carcinoma

Interventions

• DRUG
• RADIATION

No Results Yet

NCT05336955 | ACTIVE_NOT_RECRUITING | NA

339 participants

Evaluation of Telehealth Services on Mental Health Outcomes for People With Intellectual and Developmental Disabilities

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2023-05-01

Completion:

2027-01-01

Conditions

• Mental Health Conditions
• Developmental Disability

Interventions

• OTHER

No Results Yet

NCT05335369 | COMPLETED | NA

161 participants

A Patient-Centered Communication Tool (UR-GOAL) Versus Usual Care for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their Oncologists

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-06-17

Completion:

2025-04-07

Conditions

• Acute Myeloid Leukemia

Interventions

• BEHAVIORAL

Results Available

NCT05334069 | RECRUITING

2000 participants

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-11

Start Date:

2022-08-18

Completion:

2027-01-31

Conditions

• Acute Lymphoblastic Leukemia
• Acute Myeloid Leukemia
• Ann Arbor Stage I Lymphoma
• Ann Arbor Stage II Lymphoma
• Ann Arbor Stage III Lymphoma
• Ann Arbor Stage IV Lymphoma
• Chronic Lymphocytic Leukemia
• Chronic Myeloid Leukemia
• Gastroesophageal Junction Adenocarcinoma
• Head and Neck Carcinoma
• Hematopoietic and Lymphoid Cell Neoplasm
• Invasive Breast Carcinoma
• Kidney Carcinoma
• Malignant Hepatobiliary Neoplasm
• Malignant Solid Neoplasm
• Melanoma
• Muscle-Invasive Bladder Carcinoma
• RISS Stage I Plasma Cell Myeloma
• RISS Stage II Plasma Cell Myeloma
• RISS Stage III Plasma Cell Myeloma
• Sarcoma
• Stage I Bladder Cancer AJCC v6 and v7
• Stage I Breast Cancer AJCC v7
• Stage I Colorectal Cancer AJCC v6 and v7
• Stage I Esophageal Cancer AJCC V7
• Stage I Gastric Cancer AJCC V7
• Stage I Lung Cancer AJCC v7
• Stage I Ovarian Cancer AJCC v6 and v7
• Stage I Pancreatic Cancer AJCC v6 and v7
• Stage I Prostate Cancer AJCC v7
• Stage I Uterine Corpus Cancer AJCC v7
• Stage II Bladder Cancer AJCC v6 and v7
• Stage II Breast Cancer AJCC v6 and v7
• Stage II Colorectal Cancer AJCC v7
• Stage II Esophageal Cancer AJCC v7
• Stage II Gastric Cancer AJCC v7
• Stage II Lung Cancer AJCC v7
• Stage II Ovarian Cancer AJCC v6 and v7
• Stage II Pancreatic Cancer AJCC v6 and v7
• Stage II Prostate Cancer AJCC v7
• Stage II Uterine Corpus Cancer AJCC v7
• Stage III Bladder Cancer AJCC v6 and v7
• Stage III Breast Cancer AJCC v7
• Stage III Colorectal Cancer AJCC v7
• Stage III Esophageal Cancer AJCC v7
• Stage III Gastric Cancer AJCC v7
• Stage III Lung Cancer AJCC v7
• Stage III Ovarian Cancer AJCC v6 and v7
• Stage III Pancreatic Cancer AJCC v6 and v7
• Stage III Prostate Cancer AJCC v7
• Stage III Uterine Corpus Cancer AJCC v7
• Stage IV Bladder Cancer AJCC v7
• Stage IV Breast Cancer AJCC v6 and v7
• Stage IV Colorectal Cancer AJCC v7
• Stage IV Esophageal Cancer AJCC v7
• Stage IV Gastric Cancer AJCC v7
• Stage IV Lung Cancer AJCC v7
• Stage IV Ovarian Cancer AJCC v6 and v7
• Stage IV Pancreatic Cancer AJCC v6 and v7
• Stage IV Prostate Cancer AJCC v7
• Stage IV Uterine Corpus Cancer AJCC v7
• Thyroid Gland Carcinoma

Interventions

• OTHER
• PROCEDURE

No Results Yet

NCT05319873 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

18 participants

Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-04-07

Completion:

2027-04-01

Conditions

• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage IIA Breast Cancer AJCC v8
• Anatomic Stage IIB Breast Cancer AJCC v8
• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IIIA Breast Cancer AJCC v8
• Anatomic Stage IIIB Breast Cancer AJCC v8
• Anatomic Stage IIIC Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Invasive Breast Carcinoma
• Locally Advanced HER2-Positive Breast Carcinoma
• Metastatic HER2-Positive Breast Carcinoma
• Prognostic Stage IB Breast Cancer AJCC v8
• Prognostic Stage II Breast Cancer AJCC v8
• Prognostic Stage IIA Breast Cancer AJCC v8
• Prognostic Stage IIB Breast Cancer AJCC v8
• Prognostic Stage III Breast Cancer AJCC v8
• Prognostic Stage IIIA Breast Cancer AJCC v8
• Prognostic Stage IIIB Breast Cancer AJCC v8
• Prognostic Stage IIIC Breast Cancer AJCC v8
• Prognostic Stage IV Breast Cancer AJCC v8

Interventions

• DRUG
• BIOLOGICAL
• OTHER

No Results Yet

NCT05300997 | RECRUITING

650 participants

Translational Immunodiagnostics in Stroke (TrImS)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-11

Start Date:

2022-05-01

Completion:

2027-08-31

Conditions

• Acute Ischemic Stroke
• Haemorrhagic Stroke
• Transient Ischemic Attacks
• Cardioembolic Stroke
• Large-Artery Atherosclerosis (Embolus/Thrombosis)
• Small Vessel Disease
• Stroke of Other Determined Etiology
• Stroke of Undetermined Etiology
• Atrial Fibrillation
• Stroke of Anterior Cerebral Artery
• Stroke of Middle Cerebral Artery
• Stroke of Basilar Artery

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05284552 | RECRUITING | PHASE2

40 participants

Tinzaparin And Biomarkers After Neoadjuvant Treatment of Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-07-12

Completion:

2027-12-31

Conditions

• Epithelial Ovarian Cancer

Interventions

• DRUG

No Results Yet

NCT05264779 | RECRUITING | NA

300 participants

The Periviable GOALS Decision Support Tool

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-06-06

Completion:

2026-08-31

Conditions

• Pregnancy Preterm
• Premature Birth
• Pregnancy Complications
• Obstetric Labor, Premature
• Obstetric Labor Complications

Interventions

• OTHER

No Results Yet

NCT05255042 | COMPLETED

36 participants

Tissue Models for Liver Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-11

Start Date:

2021-09-08

Completion:

2025-06-25

Conditions

• Liver Diseases

Interventions

• OTHER

No Results Yet

NCT05250037 | RECRUITING

250 participants

The Longitudinal Impact of Respiratory Viruses on Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Cell Transplantation (The RV-BOS Study)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-11

Start Date:

2022-03-30

Completion:

2027-12-31

Conditions

• Bronchiolitis Obliterans Syndrome
• Hematopoietic and Lymphoid Cell Neoplasm

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT05243550 | ACTIVE_NOT_RECRUITING | PHASE3

240 participants

A Phase 3 Single-Arm Study of UGN-102 for Treatment of Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2022-03-01

Completion:

2023-04-26

Conditions

• Bladder Cancer
• Urothelial Carcinoma
• Urothelial Carcinoma Bladder

Interventions

• DRUG

Results Available

NCT05235464 | RECRUITING | NA

24 participants

High Protein Diet and Atherosclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-11

Start Date:

2023-03-13

Completion:

2027-03-31

Conditions

• Atherosclerosis

Interventions

• OTHER

No Results Yet