Clinical Trials

NCT06577025 | ACTIVE_NOT_RECRUITING | PHASE2

43 participants

A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-08-20
Completion:: 2030-09-02

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06576128 | RECRUITING | NA

100 participants

Ultrasound-Guided Transversus Abdominis Plan (TAP) Block in Endovascular Cardiac Interventions

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-09-10
Completion:: 2026-10-15

Conditions

Anesthesiology
Percutaneous Coronary Intervention
Cardiac Catheterization
Analgesia
Satisfaction, Patient

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT06566209 | TERMINATED

2 participants

FDG-PET as an Imaging Modality to Diagnose and Risk Stratify Subclinical, Imaging Negative Ici-Myocarditis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-10-11
Completion:: 2025-12-22

Conditions

Subclinical Immune Checkpoint Inhibitor-Induced Myocarditis
Myocarditis
ICI-Myocarditis
Solid Malignant Tumor
Hematologic Malignancy
Subclinical Myocarditis
Subclinical ICI-myocarditis

Interventions

DEVICE

No Results Yet

NCT06565442 | NOT_YET_RECRUITING

20 participants

Feasibility of Using NeuraSignal Transcranial Doppler Robot

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-08
Start Date:: 2026-06-15
Completion:: 2026-12-14

Conditions

Cerebral Autoregulation

Interventions

DEVICE

No Results Yet

NCT06564623 | RECRUITING | PHASE1

25 participants

Targeting Driver Oncogenes With a Peptide Vaccine Plus Durvalumab and Tremelimumab for Patients With Biliary Tract Cancers (BTC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2025-05-27
Completion:: 2029-03-31

Conditions

Biliary Tract Cancers

Interventions

DRUG

No Results Yet

NCT06559332 | RECRUITING | NA

546 participants

Coronary Artery Disease Assessment Strategies in TAVI Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2025-03-11
Completion:: 2030-03-31

Conditions

Transcatheter Aortic Valve Replacement
Coronary Artery Disease
Heart Disease Risk Factors

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06559306 | RECRUITING | PHASE3

752 participants

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-07-25
Completion:: 2026-12-30

Conditions

Depressive Disorder, Major

Interventions

DRUG

No Results Yet

NCT06559228 | ACTIVE_NOT_RECRUITING | PHASE2

400 participants

ConnectedNest: a Digital Platform Connecting Individuals With Cancer to Social Care

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2025-06-12
Completion:: 2026-08-15

Conditions

Cancer

Interventions

OTHER

No Results Yet

NCT06550895 | ACTIVE_NOT_RECRUITING | PHASE2

11 participants

A Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-09-16
Completion:: 2026-08-31

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06547749 | NOT_YET_RECRUITING

63 participants

Serum Vitamin D Status in Critically Ill Children With Acute Respiratory Infections

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-08
Start Date:: 2026-06-30
Completion:: 2027-03-31

Conditions

Acute Respiratory Infections
Critical Illness in Children
Vitamin D Deficiency
Pediatric Respiratory Infections
Respiratory Distress

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06546137 | RECRUITING

1211 participants

National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-08
Start Date:: 2025-04-30
Completion:: 2026-08-31

Conditions

Cardiomyopathy, Hypertrophic
Cardiomyopathy, Dilated
Cardiomyopathy Restrictive
Arrhythmogenic Right Ventricular Dysplasia
Non-Compaction Cardiomyopathy
Familial Hypercholesterolemia
Marfan Syndrome
Ehlers-Danlos Syndrome, Vascular Type
Loeys-Dietz Syndrome
Long QT Syndrome
Short Qt Syndrome
Brugada Syndrome
Catecholaminergic Polymorphic Ventricular Tachycardia
Sudden Cardiac Death

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06540144 | ENROLLING_BY_INVITATION | PHASE3

12 participants

An Extension Study Evaluating 6-week Treatment Cycles of Rozanolixizumab in Pediatric Study Participants With Generalized Myasthenia Gravis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-10-08
Completion:: 2027-08-17

Conditions

Generalized Myasthenia Gravis

Interventions

DRUG

No Results Yet

NCT06529991 | COMPLETED | NA

30 participants

Self-Myofascial Release of the Upper Cervical Muscles

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-06-26
Completion:: 2026-03-15

Conditions

Suboccipital Muscles
Superficial Back Line
Myofascial Release

Interventions

DEVICE

No Results Yet

NCT06528873 | RECRUITING | PHASE4

122 participants

COMS for Chronic Ulcers Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2025-10-01
Completion:: 2026-08-31

Conditions

Wound Heal
Venous Leg Ulcer
Magnetic Field Exposure

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06525220 | RECRUITING | PHASE3

700 participants

A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-09-25
Completion:: 2028-01-31

Conditions

Head and Neck Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT06507618 | RECRUITING | PHASE3

354 participants

Pre-Operative Window of ET to Inform RT Decisions (POWER II)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-07-19
Completion:: 2029-06-30

Conditions

Breast Cancer Female

Interventions

DRUG

No Results Yet

NCT06507176 | TERMINATED | NA

224 participants

Comparison of the Efficacy of Flexible Ureteroscope and Percutaneous Nephroscopic Surgery in the Treatment of 2-4cm Kidney Stones

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-07-21
Completion:: 2026-04-15

Conditions

Kidney Stone

Interventions

PROCEDURE

No Results Yet

NCT06501118 | RECRUITING | NA

3600 participants

Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-09-01
Completion:: 2026-07-08

Conditions

Respiratory Failure
Acute Hypoxemic Respiratory Failure
Acute Hypoxic Respiratory Failure
Hypoxemia
Hypoxia
Hypoxic Respiratory Failure

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT06501001 | COMPLETED | NA

200 participants

Time Restricted Eating (TRE) and High-Intensity Interval Training (HIIT) to Improve Health in Patients With Metabolic Syndrome (METS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-09-01
Completion:: 2026-04-01

Conditions

Metabolic Syndrome
Exercise
Weight Loss
Obesity
Cardiometabolic Syndrome
Time Restricted Eating

Interventions

BEHAVIORAL

No Results Yet

NCT06500884 | RECRUITING | PHASE2

210 participants

A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-08-26
Completion:: 2030-05-30

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06491017 | RECRUITING | NA

26 participants

Effects of Mechanical Insufflation-Exsufflation With Optimized Settings on Wet Mucus Volume During Invasive Ventilation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2026-05-08
Completion:: 2026-12-31

Conditions

Mucus Retention
Mechanical Ventilation Complication

Interventions

DEVICE

No Results Yet

NCT06483061 | RECRUITING | PHASE2

50 participants

Enhanced MRI Imaging in Healthy Participants and Participants With Epilepsy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2025-05-01
Completion:: 2029-09-01

Conditions

Epilepsy, Temporal Lobe

Interventions

DRUG

No Results Yet

NCT06481735 | RECRUITING | PHASE1/PHASE2

30 participants

TCR Reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B-ALL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2025-02-15
Completion:: 2027-02-15

Conditions

Acute Lymphocytic Leukemia

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06472778 | COMPLETED

431 participants

A Real-world Study in Participants With Smoldering Multiple Myeloma

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-05-31
Completion:: 2025-12-31

Conditions

Smoldering Multiple Myeloma

No Results Yet

NCT06470438 | ACTIVE_NOT_RECRUITING | PHASE1

58 participants

A Study of JNJ-88998377 for Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-05-28
Completion:: 2027-10-29

Conditions

Lymphoma, Non-Hodgkin
Refractory B-Cell NHL
Relapsed B-cell NHL

Interventions

DRUG

No Results Yet

NCT06449651 | RECRUITING | PHASE3

39 participants

A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-11-11
Completion:: 2029-12-05

Conditions

Thrombocytopenia, Neonatal Alloimmune

Interventions

DRUG

No Results Yet

NCT06448312 | ACTIVE_NOT_RECRUITING | PHASE3

406 participants

A Study of SKB264 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-06-07
Completion:: 2026-11-30

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06446063 | TERMINATED

19 participants

Efficacy & Tolerance of Cosmetic Product RV5098A on Face Pigmentation Maintenance in Adult Vitiligo Patients.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-05-23
Completion:: 2025-10-31

Conditions

Vitiligo

Interventions

OTHER

No Results Yet

NCT06445114 | RECRUITING | PHASE2

50 participants

Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2025-05-12
Completion:: 2032-06-30

Conditions

Oropharyngeal Cancer
Carcinoma

Interventions

DRUG

No Results Yet

NCT06435312 | ENROLLING_BY_INVITATION | PHASE3

8 participants

An Open-label Extension Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-11-19
Completion:: 2027-10-26

Conditions

Generalized Myasthenia Gravis

Interventions

DRUG

No Results Yet

NCT06433596 | ACTIVE_NOT_RECRUITING | NA

116 participants

Autologous PRP and Focal Shock Waves for Erectile Dysfunction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-05-06
Completion:: 2026-08-31

Conditions

Erectile Dysfunction

Interventions

OTHER

No Results Yet

NCT06431685 | RECRUITING | PHASE1

10 participants

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-04-25
Completion:: 2025-03-28

Conditions

NSCLC
Low Dose Radiotherapy
PD-1 Inhibitor
Leptomeningeal Metastasis

Interventions

RADIATION
DRUG

No Results Yet

NCT06429540 | COMPLETED | NA

26 participants

Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus Xenograft

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-03-01
Completion:: 2025-07-30

Conditions

Socket Preservation

Interventions

BIOLOGICAL

No Results Yet

NCT06429436 | RECRUITING | PHASE4

4000 participants

Vending Machine Naloxone Distribution for Your Community (VENDY)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-06-01
Completion:: 2026-06-30

Conditions

Harm Reduction
Naloxone
Opioid Overdose

Interventions

BEHAVIORAL

No Results Yet

NCT06428331 | RECRUITING | PHASE1

150 participants

A Study of SKB518 in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-07-04
Completion:: 2026-06-30

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT06409598 | COMPLETED | NA

27 participants

NOVEL Program for Stroke Telerehabilitation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-07-31
Completion:: 2026-04-28

Conditions

Chronic Stroke

Interventions

OTHER

No Results Yet

NCT06408935 | ACTIVE_NOT_RECRUITING | PHASE3

120 participants

Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-04-17
Completion:: 2027-06-08

Conditions

Crohn's Disease

Interventions

DRUG

No Results Yet

NCT06395948 | ACTIVE_NOT_RECRUITING | PHASE2

470 participants

A Study Evaluating APG777 in Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2024-04-29
Completion:: 2026-11-30

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT06387745 | RECRUITING | NA

200 participants

Referral of Patients to Hepatology With Hepatoscope

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2025-08-22
Completion:: 2026-08-31

Conditions

Chronic Liver Disease

Interventions

DEVICE

No Results Yet

NCT06386510 | RECRUITING | NA

74 participants

Cranial Nerve Neuromodulation to Improve Arm Function and Brain Plasticity in Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2026-05-08
Start Date:: 2025-06-02
Completion:: 2027-08-01

Conditions

Stroke

Interventions

PROCEDURE

No Results Yet