Clinical Trials Updated in 2025

NCT04912505 | COMPLETED | PHASE2

4 participants

ASPirin in Immune thRombocytopenia Patients With Cardiovascular disEase

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2023-01-16
Completion:: 2024-01-02

Conditions

Purpura, Thrombocytopenic

Interventions

DRUG

No Results Yet

NCT04838743 | COMPLETED

244 participants

GOAL: A Research Study Looking at Long Term Blood Sugar Control in People With Type 2 Diabetes Treated With Xultophy® in Local Clinical Practice in Japan.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-04-23
Completion:: 2022-10-26

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT04805788 | TERMINATED | PHASE2

9 participants

Stereotactic Body Proton Radiotherapy for the Treatment of Liver Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-08-24
Completion:: 2024-02-15

Conditions

Recurrent Hepatocellular Carcinoma
Stage I Hepatocellular Carcinoma AJCC v8
Stage II Hepatocellular Carcinoma AJCC v8
Stage III Hepatocellular Carcinoma AJCC v8

Interventions

RADIATION
OTHER

No Results Yet

NCT04800484 | RECRUITING | NA

40 participants

The Effects of AFO Heel Height and Stiffness on Gait

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2019-11-07
Completion:: 2027-01-01

Conditions

Musculoskeletal Injury
Musculoskeletal Diseases
Peripheral Nervous System Diseases

Interventions

DEVICE

No Results Yet

NCT04779957 | COMPLETED | PHASE2

18 participants

Evaluation of the Safety of Use of Anti-IL6 Receptor Antibodies to Reduce Allo-sensitization Post Allograft Nephrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-10-01
Completion:: 2024-08-09

Conditions

Kidney Transplantation
Graft Failure

Interventions

DRUG

No Results Yet

NCT04763980 | RECRUITING | NA

72 participants

Community-Based Health Coach for Access to Germline Genetic Testing Among African American Men With Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-01-15
Completion:: 2027-03-31

Conditions

Prostate Carcinoma

Interventions

OTHER

No Results Yet

NCT04745221 | RECRUITING | NA

100 participants

Efficacy and Safety of Auto-FMT in Preventing aGVHD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-03-01
Completion:: 2026-03-01

Conditions

Graft Versus Host Disease, Acute

Interventions

OTHER

No Results Yet

NCT04737460 | ACTIVE_NOT_RECRUITING | PHASE1

4 participants

Study for the Treatment for CLN7 Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-05-04
Completion:: 2028-02-01

Conditions

CLN7

Interventions

GENETIC

No Results Yet

NCT04660487 | RECRUITING

100 participants

Relationship Between "FODMAPs" and "GVHD"

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-12-01
Completion:: 2026-12-01

Conditions

Graft Versus Host Disease

No Results Yet

NCT04621435 | RECRUITING | PHASE1

191 participants

Imaging of Solid Tumors Using FAP-2286

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-12-14
Completion:: 2026-12-31

Conditions

Solid Tumors, Adult
Metastatic Cancer

Interventions

DRUG
PROCEDURE

No Results Yet

NCT04601857 | TERMINATED | PHASE2

43 participants

Futibatinib and Pembrolizumab Combination in the Treatment of Advanced or Metastatic Urothelial Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-01-07
Completion:: 2024-03-08

Conditions

Advanced and Metastatic Urothelial Cancer

Interventions

DRUG

Results Available

NCT04560673 | RECRUITING | PHASE2

380 participants

Duloxetine and Neurofeedback Training for the Treatment of Chemotherapy Induced Peripheral Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-07-10
Completion:: 2026-12-31

Conditions

Chemotherapy-Induced Peripheral Neuropathy
Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm

Interventions

DRUG
BEHAVIORAL
OTHER

No Results Yet

NCT04542733 | RECRUITING | NA

50 participants

The Efficacy of Everolimus With Reduced-dose Tacrolimus Versus Reduced-dose Tacrolimus and Leflunomide in Treatment of BK Virus Infection in Kidney Transplantation Recipient

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-02-10
Completion:: 2025-12-24

Conditions

Kidney Transplant Infection
BK Virus Infection

Interventions

DRUG

No Results Yet

NCT04453917 | COMPLETED | NA

22 participants

Dynamics of T Cell Expression of Immune Checkpoint Molecules in Progressive Multifocal Leukoencephalopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2021-02-23
Completion:: 2024-07-12

Conditions

Progressive Multifocal Leukoencephalopathy

Interventions

BIOLOGICAL
DIAGNOSTIC_TEST

No Results Yet

NCT04451135 | ACTIVE_NOT_RECRUITING | NA

31 participants

CET- REM (Correlating ECT Response to EEG Markers)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-10-09
Completion:: 2026-06-30

Conditions

ECT
Treatment Resistant Depression

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04443660 | COMPLETED

97 participants

Autophagy/Apoptosis Balance During Pregnancy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-12-30
Completion:: 2024-09-30

Conditions

Pregnancy Related

Interventions

OTHER

No Results Yet

NCT04364217 | WITHDRAWN | NA

0 participants

Pain and Itch Reduction in Burn Scars Treated With Fractional CO2 Laser

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-06-25
Completion:: 2025-03-31

Conditions

Hypertrophic Scar
Burn Scar

Interventions

DEVICE

No Results Yet

NCT04356755 | RECRUITING | PHASE2

32 participants

Subcutaneous Injections of ASC to Heal Digital Ulcers in Patients With Scleroderma.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-09-22
Completion:: 2027-03-31

Conditions

Systemic Sclerosis

Interventions

DRUG

No Results Yet

NCT04353375 | RECRUITING | PHASE2/PHASE3

235 participants

HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-09-03
Completion:: 2028-06-30

Conditions

Advanced Intrahepatic Cholangiocarcinoma
Solid Tumor, Adult

Interventions

DRUG

No Results Yet

NCT04311606 | COMPLETED | PHASE2

11 participants

Anti-VEGF Therapy for Acute Thyroid Eye Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-11-02
Completion:: 2024-12-17

Conditions

Thyroid Eye Disease

Interventions

DRUG

No Results Yet

NCT04307134 | COMPLETED

108 participants

Besponsa Post Marketing Surveillance Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-07-09
Completion:: 2024-12-24

Conditions

Hematologic Malignancy

Interventions

DRUG

Results Available

NCT04227509 | COMPLETED | PHASE2

53 participants

Consolidation Pembrolizumab After Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-06-04
Completion:: 2024-08-21

Conditions

Nasopharyngeal Carcinoma

Interventions

DRUG

No Results Yet

NCT04224337 | COMPLETED | PHASE2

16 participants

Phase II Study of Durvalumab ,Doxorubicin, and Ifosfamide in Pulmonary Sarcomatoid Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-06-11
Completion:: 2023-08-14

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG

No Results Yet

NCT04203160 | TERMINATED | PHASE1/PHASE2

75 participants

Gemcitabine and Cisplatin With or Without CPI-613 as First Line Therapy for Patients With Advanced Unresectable Biliary Tract Cancer (BilT-04)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-06-23
Completion:: 2024-04-16

Conditions

Biliary Tract Cancer

Interventions

DRUG

Results Available

NCT04192435 | COMPLETED | PHASE4

3300 participants

Tranexamic Acid to Reduce Infection After Gastrointestinal Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2022-05-18
Completion:: 2025-09-13

Conditions

Infection Wound
Gastrointestinal Complication
Anesthesia
Bleeding
Healthcare Associated Infection

Interventions

DRUG

No Results Yet

NCT04172922 | TERMINATED | PHASE1

5 participants

Topical Rapamycin/Sirolimus for Complicated Vascular Anomalies and Other Susceptible Lesions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-04-01
Completion:: 2024-02-15

Conditions

Vascular Anomaly

Interventions

DRUG

No Results Yet

NCT04141449 | ACTIVE_NOT_RECRUITING | PHASE2

874 participants

A Multilevel Intervention to Improve Timely Cancer Detection and Treatment Initiation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-11-18
Completion:: 2026-09-30

Conditions

Neoplasms
Hiv
Cervical Cancer
Breast Cancer
HNSCC
Vulvar Cancer
Anal Cancer
Cancer Suspect

Interventions

OTHER

No Results Yet

NCT04124198 | ACTIVE_NOT_RECRUITING | NA

138 participants

Quality of Life After Primary TORS vs IMRT for Patients With Early-stage Oropharyngeal Squamous Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2019-03-01
Completion:: 2025-12-16

Conditions

Oropharynx Cancer
Oropharynx Squamous Cell Carcinoma
Carcinoma, Squamous Cell
Carcinoma
Oropharyngeal Neoplasms
Neoplasms, Squamous Cell
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Pharyngeal Neoplasms Malignant and Unspecified
Otorhinolaryngologic Neoplasms
Head and Neck Neoplasms
Neoplasms by Site
Otorhinolaryngologic Diseases
Pharyngeal Diseases
Papillomavirus Infections
Virus Diseases
DNA Virus Infections
Tumor Virus Infections
Quality of Life

Interventions

RADIATION
DRUG
PROCEDURE

No Results Yet

NCT04116905 | COMPLETED | NA

68 participants

Intensive Lifestyle Intervention for Remission of Metabolic Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-10-01
Completion:: 2022-08-31

Conditions

Metabolic Syndrome

Interventions

BEHAVIORAL

No Results Yet

NCT04115319 | COMPLETED | PHASE3

305 participants

A Study of the Long-term Safety and Tolerability of an Investigational Drug in People With Schizophrenia.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2019-11-21
Completion:: 2022-12-30

Conditions

Schizophrenia

Interventions

DRUG

Results Available

NCT04091009 | WITHDRAWN | PHASE4

0 participants

Effect of Standard of Care Reduced Dose Versus Full Dose Buprenorphine/Naloxone in the Perioperative Period on Pain Control and Post-Operative Opioid Use Disorder Symptoms

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2019-10-31
Completion:: 2025-12-31

Conditions

Opioid-use Disorder
Opioid Use Disorder, Mild

Interventions

DRUG

No Results Yet

NCT04064086 | ACTIVE_NOT_RECRUITING | NA

656 participants

Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2020-03-25
Completion:: 2025-09-30

Conditions

Chronic Kidney Disease
End Stage Renal Disease
Hemodialysis
Peritoneal Dialysis

Interventions

OTHER

No Results Yet

NCT04002596 | COMPLETED | NA

10 participants

Safety and Initial Effectiveness of Transcranial MR Guided Focused Ultrasound for the Treatment of Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2017-02-06
Completion:: 2018-12-05

Conditions

Parkinson Disease

Interventions

DEVICE

No Results Yet

NCT03978767 | COMPLETED | PHASE2

287 participants

Preeclampsia And Nonsteroidal Drugs for Analgesia: a Randomized Non Inferiority Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2019-06-10
Completion:: 2025-07-31

Conditions

Preeclampsia Severe
Preeclampsia Postpartum

Interventions

DRUG

No Results Yet

NCT03955185 | ACTIVE_NOT_RECRUITING | NA

2000 participants

Clinical Trial of Minimally Invasive Surgery Versus Abdominal Surgery in Patients With Early Stage Cervical Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2019-05-01
Completion:: 2026-05-01

Conditions

Uterine Cervical Neoplasm

Interventions

PROCEDURE

No Results Yet

NCT03942653 | RECRUITING | PHASE2

20 participants

Androgen Deprivation Therapy (ADT) and Pembrolizumab for Advanced Stage Androgen Receptor-positive Salivary Gland Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2019-05-30
Completion:: 2026-04-30

Conditions

Salivary Gland Carcinoma

Interventions

DRUG

No Results Yet

NCT03926117 | COMPLETED | PHASE2

264 participants

Trial to Evaluate Reduction in Inflammation in Patients With Advanced Chronic Renal Disease Utilizing Antibody Mediated IL-6 Inhibition

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2019-06-03
Completion:: 2020-06-26

Conditions

Chronic Kidney Diseases
Inflammation

Interventions

BIOLOGICAL

Results Available

NCT03844750 | TERMINATED | PHASE2

6 participants

Preoperative Immunotherapy (Pembrolizumab) for Patients With Colorectal Cancer and Resectable Hepatic Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2019-07-22
Completion:: 2025-09-30

Conditions

Metastatic Malignant Neoplasm in the Liver
Stage IV Colorectal Cancer AJCC v8
Stage IVA Colorectal Cancer AJCC v8
Stage IVB Colorectal Cancer AJCC v8
Stage IVC Colorectal Cancer AJCC v8

Interventions

PROCEDURE
BIOLOGICAL
DRUG

Results Available

NCT03840993 | COMPLETED | PHASE2

76 participants

Safety and Efficacy Study of MT-2990 in Women With Endometriosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2019-01-15
Completion:: 2021-05-13

Conditions

Endometrial Related Pain

Interventions

DRUG

Results Available

NCT03809039 | TERMINATED | PHASE1

52 participants

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of MT-6345 in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-31
Start Date:: 2019-01-15
Completion:: 2019-07-01

Conditions

Healthy

Interventions

DRUG

Results Available