Clinical Trials Updated in 2025

NCT07292064 | COMPLETED

90 participants

Type D Personality, Somatization and Perceived Social Support in Temporomandibular Joint Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-02-20
Completion:: 2025-06-30

Conditions

Temporomandibular Joint Disorders
Somatization Disorder
Type D Personality
Perceived Social Support

No Results Yet

NCT07291882 | COMPLETED

400 participants

Serum Hyperbilirubinemia as an Early Predictive Factor for Complicated Appendicitis: Single Center Experience

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-09-01
Completion:: 2024-09-10

Conditions

Appendicitis, Surgery

Interventions

PROCEDURE

No Results Yet

NCT07291440 | COMPLETED | NA

40 participants

Impact of Balneotherapy in Ma'n Hot Spring on Quality of Life in Adults With Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-06-01
Completion:: 2025-10-18

Conditions

Low Back Pain

Interventions

OTHER

No Results Yet

NCT07287072 | NOT_YET_RECRUITING | NA

12 participants

Pain Reprocessing Therapy for Chronic Primary Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-02-01
Completion:: 2026-07-31

Conditions

Nociplastic Pain
Chronic Primary Pain

Interventions

BEHAVIORAL

No Results Yet

NCT07286357 | ACTIVE_NOT_RECRUITING

100 participants

A Data Collection Protocol to Evaluate the Real World Usage of the Orthofix AccelStim Device to Treat Fresh Metatarsal Fractures

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-05-30
Completion:: 2026-06-30

Conditions

Metatarsal Fracture

Interventions

DEVICE

No Results Yet

NCT07283107 | ENROLLING_BY_INVITATION | NA

8910 participants

Trial to Evaluate the Impact of Various Behavioural Interventions to Increase Mammography Uptake Among Singaporean Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-11-17
Completion:: 2026-12-31

Conditions

This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women

Interventions

BEHAVIORAL

No Results Yet

NCT07282392 | RECRUITING | NA

30 participants

Helping Lupus Patients Manage Fibromyalgia Symptoms Through Emotional Awareness and Expression Therapy (EAET)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-12-01
Completion:: 2028-10-15

Conditions

Lupus
Fibromyalgia (FM)
Chronic Widespread Pain

Interventions

BEHAVIORAL

No Results Yet

NCT07282067 | ACTIVE_NOT_RECRUITING

200 participants

Orthofix PhysioStim PEMF Ankle Fusion Retrospective

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-01-23
Completion:: 2026-03-31

Conditions

Ankle Fusion
Hindfoot Arthrodesis
Ankle Arthrodesis
Tibiotalar Arthrodesis

Interventions

DEVICE
OTHER

No Results Yet

NCT07279987 | NOT_YET_RECRUITING | NA

162 participants

Comparison of RA-IVL and RA-SHP in Calcified Coronary Lesions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-01-01
Completion:: 2027-12-31

Conditions

Vascular Calcification

Interventions

DEVICE

No Results Yet

NCT07279792 | COMPLETED | PHASE2/PHASE3

150 participants

Implications of Post-Operative Irrigation Fluid's Osmolarity on the Recurrence of Non-Muscle Invasive Bladder Cancer Following Transurethral Resection

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-10-01
Completion:: 2025-08-01

Conditions

Bladder (Urothelial, Transitional Cell) Cancer
Nonmuscle Invasive Bladder Cancer
Irrigation
Hypertonic Saline
Normal Saline
Distilled Water

Interventions

DRUG

No Results Yet

NCT07276945 | NOT_YET_RECRUITING

300 participants

Individualized Early Diagnosis and Treatment System of Gestational Diabetes Mellitus (GDM) Based on New Continuous Glucose Monitoring (CGM) Technology

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-12-10
Completion:: 2028-07-01

Conditions

Gestational Diabetes

Interventions

OTHER

No Results Yet

NCT07276230 | NOT_YET_RECRUITING | NA

27 participants

Quality of Life Assessment of Caregivers of Patients With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-02-01
Completion:: 2027-05-01

Conditions

Caregivers of Patients With Multiple Myeloma

Interventions

OTHER

No Results Yet

NCT07265622 | RECRUITING | PHASE1/PHASE2

200 participants

First-in-human Study of 7MW4911 in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-11-12
Completion:: 2027-07-31

Conditions

Solid Tumors

Interventions

DRUG

No Results Yet

NCT07261020 | COMPLETED | NA

40 participants

The Effectiveness of Pilates in Women With Lumbar Disc Herniation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-01-05
Completion:: 2024-03-15

Conditions

Disc Herniation
Kinesiophobia
Low Back Pain

Interventions

OTHER

No Results Yet

NCT07260890 | RECRUITING

300 participants

Paired Comparison of SVV and PVI Accuracy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-10-01
Completion:: 2025-10-22

Conditions

Perioperative Care
Fluid Therapy
Monitoring, Physiologic
Hemodynamics
Laparoscopy

Interventions

DEVICE

No Results Yet

NCT07253610 | COMPLETED | NA

56 participants

Effect of Bilateral Rectointercostal Fascial Plane Block on Postoperative Pain After Laparoscopic Sleeve Gastrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-11-01
Completion:: 2025-12-21

Conditions

Obesity, Morbid
Pain, Postoperative
Laparoscopic Sleeve Gastrectomy (LSG)
Opioid Use

Interventions

OTHER

No Results Yet

NCT07252193 | COMPLETED | NA

120 participants

Generative AI-Based Simulation for Diagnostic Communication in Type 2 Diabetes (DIALOGUE-DM2)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-22
Completion:: 2025-12-18

Conditions

Type 2 Diabetes Mellitus
Medical Education
Diagnostic Communication
Artificial Intelligence Simulation

Interventions

BEHAVIORAL

No Results Yet

NCT07244653 | NOT_YET_RECRUITING | NA

70 participants

Hologram Burn Dressing on Pain, Anxiety, Fear, Patient Satisfaction, and Physiological Parameters

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-12-31
Completion:: 2026-06-20

Conditions

Anxiety
Burn Pain
Burn Patients
Fear

Interventions

OTHER

No Results Yet

NCT07228858 | COMPLETED | NA

170 participants

Uterine Scar Resection During Repeat Cesarean Delivery to Prevent Uterine Niche Formation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-02-09
Completion:: 2025-05-30

Conditions

Cesarean Section Complications
Scar Niche
Scarred Uterus

Interventions

PROCEDURE
DIAGNOSTIC_TEST

No Results Yet

NCT07228247 | RECRUITING | PHASE1/PHASE2

147 participants

A Phase Ⅰ/Ⅱa Study of HMPL-A251 in Participants With Advanced or Metastatic HER2-expressing Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-12-16
Completion:: 2028-11-30

Conditions

Solid Tumors, Adult

Interventions

DRUG

No Results Yet

NCT07224633 | COMPLETED | NA

47 participants

A Clinical In-Use Evaluation to Assess the Tolerability and Efficacy of a Moisturizer on Acne Prone Skin

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-10-07
Completion:: 2025-12-16

Conditions

Acne Vulgaris

Interventions

OTHER

No Results Yet

NCT07212946 | COMPLETED | PHASE2

22 participants

Ayahuasca and Esketamine for Major Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-10-30
Completion:: 2024-10-30

Conditions

Major Depression Severe

Interventions

DRUG

No Results Yet

NCT07211776 | RECRUITING | PHASE3

99 participants

A Study to Assess the Efficacy and Safety of ZL-1109 in Chinese Participants With Active Thyroid Eye Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-12-05
Completion:: 2027-03-14

Conditions

Thyroid Eye Disease (TED)

Interventions

DRUG

No Results Yet

NCT07203144 | NOT_YET_RECRUITING | PHASE2

172 participants

Selenium Supplementation for Improving Depression in Children and Adolescents: Efficacy and Mechanistic Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-12-31
Completion:: 2027-04-01

Conditions

Depression - Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT07200180 | RECRUITING | PHASE3

100 participants

Perioperative Argon Inhalation to Improve Neurocognitive Recovery After Carotid Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-22
Completion:: 2026-10-01

Conditions

Carotid Artery Disease
Carotid Artery Stenoses

Interventions

DRUG

No Results Yet

NCT07193498 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:: 2025-12-29

No Results Yet

NCT07191145 | NOT_YET_RECRUITING | PHASE3

80 participants

Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (ELITE-ACT)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-01-01
Completion:: 2027-06-30

Conditions

Post Traumatic Headache

Interventions

DRUG
OTHER

No Results Yet

NCT07189078 | RECRUITING | NA

200 participants

IntHyx : Intubation Strategies for Patients With Acute Hypoxemic Respiratory Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-12-13
Completion:: 2026-12-31

Conditions

Acute Hypoxemic Respiratory Failure

Interventions

PROCEDURE

No Results Yet

NCT07175623 | COMPLETED | NA

60 participants

Methylprednisolone vs Dexamethasone Interaction With Sugammadex in Pediatric Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-16
Completion:: 2025-12-20

Conditions

Neuromuscular Block, Residual
Pain Management
Postoperative Nausea

Interventions

DRUG

No Results Yet

NCT07172776 | NOT_YET_RECRUITING | NA

50 participants

A Community Engagement Approach to Improving Communication With Black Men About Oral and Pharyngeal Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-01-01
Completion:: 2026-12-31

Conditions

Oral Cancers

Interventions

BEHAVIORAL

No Results Yet

NCT07166757 | RECRUITING | PHASE1/PHASE2

90 participants

Clinical Study to Evaluate XS411 in Treatment of Early-onset Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-22
Completion:: 2028-03-30

Conditions

Parkinson Disease (PD)

Interventions

DRUG

No Results Yet

NCT07165067 | RECRUITING | PHASE1

36 participants

A Study of AP601 in Patients With Locally Unresectable Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-01-21
Completion:: 2027-12-27

Conditions

Solid Tumours

Interventions

DRUG

No Results Yet

NCT07162922 | COMPLETED | NA

76 participants

Optic Nerve Sheath Diameter Changes in Laparoscopic Cholecystectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-17
Completion:: 2025-12-21

Conditions

Increased Intracranial Pressure Disorders
Perioperative Complication
Pneumoperitoneum

Interventions

OTHER

No Results Yet

NCT07157124 | RECRUITING | NA

62 participants

Examining the Effectiveness of Dynamic Visual Noise (DVN) for Reducing Alcohol Cravings and Consumption in College Students

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-09-22
Completion:: 2026-09-30

Conditions

Craving
Alcohol Drinking

Interventions

OTHER

No Results Yet

NCT07154667 | RECRUITING | NA

30 participants

Evaluation of the Auryzon™ EAR 2.0 System in Ear Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-10-01
Completion:: 2030-12-31

Conditions

Microtia, Congenital
Microtia
Microtia-Anotia
Ear Deformities, Acquired
Ear Deformity External
Ear Malformation
Ear Cartilage

Interventions

PROCEDURE

No Results Yet

NCT07147608 | RECRUITING

118 participants

SAPHIR2 : Simplification of PHysical Activity Assessment by Rapid Interrogation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-12-19
Completion:: 2027-06-30

Conditions

General Population (no Specific Condition or Disease)

Interventions

OTHER

No Results Yet

NCT07124975 | ENROLLING_BY_INVITATION | NA

186 participants

Impact of Comparing Treatment Status With Other CPAP Users

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-10-01
Completion:: 2027-12-31

Conditions

Sleep Apnea
Obstructive Sleep Apnea

Interventions

BEHAVIORAL

No Results Yet

NCT07122219 | RECRUITING | NA

548 participants

Enhancing Uptake of Needle and Syringe Programs in Canadian Federal Prisons

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-10-01
Completion:: 2028-02-29

Conditions

HIV
Hepatitis C Virus (HCV)

Interventions

BEHAVIORAL

No Results Yet

NCT07102056 | NOT_YET_RECRUITING

152 participants

18F-AlF-NOTA-Octreotide PET in Neuroendocrine Neoplasms

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-01-01
Completion:: 2027-06-03

Conditions

Neuroendocrine Tumors

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07100210 | RECRUITING | PHASE1

6 participants

A Clinical Trial Evaluating IL-22BP/LNP Compound in Refractory Malignant Solid Tumors for Safety, Tolerability and Activity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2025-01-20
Completion:: 2026-02-20

Conditions

Refractory Malignant Solid Tumors
mRNA Vaccine
Interleukin

Interventions

BIOLOGICAL

No Results Yet