Clinical Trials Updated in 2025

NCT06076538 | RECRUITING

97 participants

PET/MR for Characterization of Renal Masses (RMs)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-08-01
Completion:: 2028-06-01

Conditions

Renal Tumor
Renal Cell Carcinoma
Renal Tumor, Benign

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06038318 | RECRUITING | NA

325 participants

Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-10-16
Completion:: 2026-12-31

Conditions

Stress
Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT06034327 | RECRUITING | NA

150 participants

Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-09-18
Completion:: 2027-01-31

Conditions

Myopia
Juvenile Myopia
Myopia Progression

Interventions

DEVICE

No Results Yet

NCT06028022 | RECRUITING | PHASE2

80 participants

Reishi Mushroom Extract for Fatigue and/or Arthralgias/Myalgias in Patients With Breast Cancer on Aromatase Inhibitors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-10-18
Completion:: 2026-10-16

Conditions

Estrogen Receptor-Positive Breast Carcinoma

Interventions

DIETARY_SUPPLEMENT
DRUG
OTHER

No Results Yet

NCT06027307 | ACTIVE_NOT_RECRUITING | PHASE3

541 participants

Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-10-25
Completion:: 2027-06-30

Conditions

Tricuspid Regurgitation
Heart Failure With Preserved Ejection Fraction

Interventions

DRUG

No Results Yet

NCT06016088 | RECRUITING | PHASE1/PHASE2

72 participants

A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-04-01
Completion:: 2026-04-30

Conditions

Cystic Fibrosis Lung
Respiratory Infections, Recurrent, Chronic
Pseudomonas Aeruginosa

Interventions

DRUG

No Results Yet

NCT06013176 | COMPLETED | NA

476 participants

Behavioral Economic Strategies to Improve PRO Adherence

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-12-04
Completion:: 2024-06-04

Conditions

Cancer

Interventions

OTHER

Results Available

NCT06011759 | COMPLETED | NA

4 participants

Maintaining Implementation Through Dynamic Adaptations (MIDAS) Suicide Prevention 2.0 Clinical Telehealth

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-11-01
Completion:: 2024-08-29

Conditions

Suicidal Self-directed Violence
Suicidal Preparatory Behavior

Interventions

BEHAVIORAL

Results Available

NCT06008691 | RECRUITING

1500 participants

A Prospective, Observational Cohort Study on the Clinical Impact of Novel Monoclonal Antibodies in B-cell Non-Hodgkin Lymphoma in Italian Clinical Practice

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-12-27
Completion:: 2038-10-31

Conditions

Non-Hodgkin Lymphoma, B-cell

Interventions

DRUG

No Results Yet

NCT05993481 | ENROLLING_BY_INVITATION | NA

640 participants

The Noninvasive Blood Pressure Measurement Effect on the Hypotension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-10-25
Completion:: 2026-11-25

Conditions

Hypotension During Surgery

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05983887 | COMPLETED | NA

12 participants

The Effect of Therapeutic Climbing on Muscle Strength, Tone and Balance in Hemiplegic Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-04-10
Completion:: 2023-08-31

Conditions

Hemiplegia and Hemiparesis

Interventions

OTHER

No Results Yet

NCT05906238 | RECRUITING | NA

210 participants

Interventions to Remedy the Negative Effects of Obesity Stigma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-10-10
Completion:: 2027-04-30

Conditions

Obesity
Stigma, Weight

Interventions

BEHAVIORAL

No Results Yet

NCT05858008 | RECRUITING | NA

15 participants

Feasibility of Implementing Time-restricted Eating in Women With Mild Cognitive Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-04-01
Completion:: 2026-06-30

Conditions

Mild Cognitive Impairment

Interventions

BEHAVIORAL

No Results Yet

NCT05829889 | RECRUITING | NA

960 participants

Fractional Flow Reserve Versus Angiography for Treatment-Decision and Evaluation of Significant Left MAIN Coronary Artery Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-04-25
Completion:: 2027-06-30

Conditions

Coronary Artery Disease Left Main
Coronary Artery Disease

Interventions

PROCEDURE

No Results Yet

NCT05816850 | RECRUITING

654 participants

Multilayer Biological Characterization of Advanced Follicular Lymphoma: a Translational Study From FIL_FOLL12 Trial

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-09-19
Completion:: 2026-12-01

Conditions

Follicular Lymphoma

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05799339 | COMPLETED

144 participants

Optimizing CAB-LA as PrEP for Women Who Inject Drugs

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-01-13
Completion:: 2025-07-31

Conditions

HIV Infections
Opioid Use
Trauma, Psychological

No Results Yet

NCT05776082 | RECRUITING

5000 participants

Association of Gestational Cardiovascular Health With Pregnancy Outcomes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-03-01
Completion:: 2026-12-31

Conditions

Pregnant Women

Interventions

OTHER

No Results Yet

NCT05770596 | COMPLETED | NA

204 participants

Vitamin C on Acute and Chronic Post Mastectomy Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-04-01
Completion:: 2024-12-03

Conditions

Vitamin C
Post-mastectomy Pain Syndrome

Interventions

DRUG
OTHER

No Results Yet

NCT05760534 | COMPLETED | PHASE4

110 participants

Ideal Dosage for Sedation of Obese Patients Undergoing Knee or Hip Arthroplasty Under Spinal Anesthesia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-03-06
Completion:: 2025-11-25

Conditions

Arthritis Knee
Arthritis Hip

Interventions

DRUG

No Results Yet

NCT05727176 | RECRUITING | PHASE2

120 participants

Study of Futibatinib in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusion or Rearrangement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-07-05
Completion:: 2026-12-31

Conditions

Advanced Cholangiocarcinoma
FGFR2 Fusions
Gene Rearrangement

Interventions

DRUG

No Results Yet

NCT05704049 | ACTIVE_NOT_RECRUITING | PHASE2

118 participants

A Study to Investigate Subcutaneous Isatuximab in Combination With Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-04-05
Completion:: 2025-12-22

Conditions

Relapsed/Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05703672 | RECRUITING | PHASE3

500 participants

Switching to E-cigarettes in Smokers Not Interested in Quitting

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-07-17
Completion:: 2026-12-07

Conditions

Smoking Reduction

Interventions

DRUG
OTHER

No Results Yet

NCT05702931 | RECRUITING | PHASE4

104 participants

Semaglutide Treatment for Hyperglycaemia After Renal Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2024-09-19
Completion:: 2027-12-31

Conditions

Hyperglycemia
Renal Transplant Complication Primary Non-Function
Diabetes

Interventions

DRUG

No Results Yet

NCT05657652 | RECRUITING | NA

36 participants

CAV Regimen for R/R Ph- B-ALL

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-10-01
Completion:: 2026-10-31

Conditions

Acute Lymphoblastic Leukemia

Interventions

DRUG

No Results Yet

NCT05657639 | RECRUITING | PHASE2

68 participants

CAV Regimen for R/R AML

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-10-01
Completion:: 2026-10-01

Conditions

Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT05650749 | RECRUITING | PHASE1

45 participants

GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-05-23
Completion:: 2028-01-30

Conditions

Refractory Neuroblastoma
Relapsed Neuroblastoma
High-risk Neuroblastoma
Retinoblastoma
Metastatic Retinoblastoma

Interventions

BIOLOGICAL

No Results Yet

NCT05641753 | RECRUITING | PHASE4

125 participants

Cholesterol Lowering and Residual Risk in Diabetes, Type 1

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-12-06
Completion:: 2027-07-01

Conditions

Type 1 Diabetes

Interventions

DRUG
DEVICE

No Results Yet

NCT05631704 | COMPLETED | PHASE1

84 participants

A Study to Investigate Safety, Tolerability, and Pharmacokinetics (PK) of VH4524184 and the Potential for Changes in Cytochrome P450 3A (CYP3A) Activity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-12-02
Completion:: 2023-07-27

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT05613712 | COMPLETED

229 participants

Chronic Inflammatory Rheumatism: Management of Comorbidities in Ambulatory Medicine

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-02-11
Completion:: 2023-05-04

Conditions

Chronic Inflammatory Disease

Interventions

OTHER

No Results Yet

NCT05610995 | TERMINATED | NA

6 participants

Feasibility Study of Early Return-home After Colorectal Surgery Using a SENSIUM® Vital Parameter Monitoring Device

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-07-22
Completion:: 2024-10-08

Conditions

Premature Exit After Colorectal Surgery

Interventions

DEVICE

No Results Yet

NCT05589220 | RECRUITING | NA

120 participants

Study to Evaluate Music Therapy and Nicotine Replacement Therapy on Craving Related to Smoking Cessation in Students

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-12-13
Completion:: 2028-01-31

Conditions

Smoking Cessation

Interventions

OTHER
DRUG

No Results Yet

NCT05581498 | NOT_YET_RECRUITING | NA

150 participants

Glaucoma Exercise as Medicine Study (GEMS).

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2026-06-30
Completion:: 2028-12-31

Conditions

Glaucoma

Interventions

BEHAVIORAL

No Results Yet

NCT05444517 | COMPLETED | NA

50 participants

Interscalene Block Versus Combined Infraclavicular-Anterior Suprascapular Blocks for Shoulder Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-06-13
Completion:: 2025-11-28

Conditions

Pain, Postoperative
Shoulder Pain
Surgical Procedure, Unspecified
Diaphragmatic Paralysis

Interventions

PROCEDURE

No Results Yet

NCT05425251 | COMPLETED

2297 participants

BRAINI-2 Elderly Mild TBI European Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-03-01
Completion:: 2024-12-31

Conditions

Mild Traumatic Brain Injury

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05422638 | COMPLETED | NA

37 participants

Race-Based Stress Trauma and Empowerment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-01-02
Completion:: 2024-09-30

Conditions

Life Stress
Racism

Interventions

BEHAVIORAL

Results Available

NCT05401240 | ACTIVE_NOT_RECRUITING | NA

200 participants

Using Cardiopulmonary Exercise Test as an Incentive to Outpatient Cardiac Rehabilitation for Acute Coronary Syndrome Survivors.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2023-09-01
Completion:: 2026-04-30

Conditions

Acute Coronary Syndrome

Interventions

BEHAVIORAL

No Results Yet

NCT05388916 | COMPLETED

42 participants

A Real-world Study to Assess Safety and Effectiveness of Secukinumab in Pediatric Plaque Psoriasis Patients in China

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-09-08
Completion:: 2025-02-27

Conditions

Moderate to Severe Chronic Plaque Psoriasis

Interventions

OTHER

No Results Yet

NCT05380713 | COMPLETED | PHASE2

30 participants

......SMARTEST Trial......

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-05-03
Completion:: 2025-08-11

Conditions

Mesothelioma, Malignant

Interventions

DRUG

No Results Yet

NCT05366699 | RECRUITING | NA

80 participants

LYMPHA Procedure for the Prevention of Lymphedema After Axillary Lymphadenectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-29
Start Date:: 2021-09-10
Completion:: 2026-06-01

Conditions

Lymphedema, Breast Cancer
Lymphedema

Interventions

PROCEDURE

No Results Yet

NCT05356377 | COMPLETED

6 participants

Preliminary Study of Brain Effects of Palynziq-Related Changes in Phenylalanine in Individuals With PKU

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-29
Start Date:: 2022-05-25
Completion:: 2025-07-01

Conditions

Phenylketonurias

Interventions

DRUG

No Results Yet