Clinical Trials Updated in 2025

NCT07197827 | RECRUITING | PHASE1/PHASE2

424 participants

A Study of YL242 in Subjects With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-09-22
Completion:: 2028-09-30

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT07194200 | RECRUITING | PHASE2

184 participants

Safety and Efficacy of Lactobacillus Plantarum for Psoriasis: A Randomized Double-Blind Placebo-Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-12-15
Completion:: 2026-06-25

Conditions

Psoriasis
Lactobacillus Plantarum

Interventions

BIOLOGICAL

No Results Yet

NCT07192939 | RECRUITING | PHASE2

270 participants

Multicenter, Randomized, Double-blind, Placebo-controlled Phase II Trial to Evaluate the Efficacy and Safety of HRS-9813 in Subjects With Pulmonary Fibrosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-10-29
Completion:: 2028-06-30

Conditions

IPF and PPF

Interventions

DRUG

No Results Yet

NCT07189676 | RECRUITING | NA

180 participants

Sustainable Diets and Cardiometabolic Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-11-24
Completion:: 2027-04-30

Conditions

Cardiometabolic Diseases

Interventions

BEHAVIORAL

No Results Yet

NCT07180875 | NOT_YET_RECRUITING | NA

60 participants

"Hypoxic vs. Aerobic Training in Chronic Kidney Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-12-09
Completion:: 2026-01-15

Conditions

Chronic Kidney Disease (CKD), Stages 3-4 Exercise Tolerance / Functional Capacity Vascular Health / Arterial Stiffness Fatigue in CKD

Interventions

BEHAVIORAL

No Results Yet

NCT07180004 | COMPLETED

70 participants

Upper Extremity Functional Skills in Patients With Parkinson Disease (pwPD)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-01-01
Completion:: 2025-12-15

Conditions

PARKINSON DISEASE (Disorder)
Upper Extremity
Muscle Strength Development
Functional Skills

No Results Yet

NCT07174401 | NOT_YET_RECRUITING | PHASE4

30 participants

Rocklatan Retinal Perfusion OCT Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2026-01-31
Completion:: 2026-12-31

Conditions

Glaucoma

Interventions

DRUG
DEVICE

No Results Yet

NCT07166549 | NOT_YET_RECRUITING | PHASE1

12 participants

Bispecific CAR T Cells for B-cell Malignancies (BaseCAR-01 Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2026-06-30
Completion:: 2028-11-30

Conditions

B Cell Malignancies
B-cell Leukemia
B Cell Lymphoma
Bispecific Chimeric Antigen Receptor (CAR) T Cells
Relapsed or Refractory (r/r) B-cell Malignancies

Interventions

DRUG

No Results Yet

NCT07157930 | COMPLETED

180 participants

Prenatal Hormonal Markers and Sleep Characteristics in Young Adults With Joint Hypermobility

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-08-20
Completion:: 2025-12-17

Conditions

Joint Hypermobility
Healty Controls
Sleep
Androgen Effect
Hormonal

Interventions

BEHAVIORAL

No Results Yet

NCT07144787 | COMPLETED | NA

10 participants

Four Implant Retained Mandibular Overdenture VERSUS Fixed-detachable Prosthesis.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-05-01
Completion:: 2024-08-01

Conditions

Oral Health Impact Profile Short Version 14 (OHIP 14)

Interventions

OTHER

No Results Yet

NCT07133919 | RECRUITING | NA

60 participants

Effect of AI-Supported Child-Friendly Communication on Dental Anxiety in Pediatric Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-10-15
Completion:: 2026-01-31

Conditions

Caries, Dental
Local Anesthesia
Inferior Alveolar Nerve Block
Dental Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT07133139 | RECRUITING | NA

80 participants

Treatment Validation for Myofascial Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-10-06
Completion:: 2027-08-31

Conditions

Chronic Low-back Pain (cLBP)
Myofacial Pain

Interventions

DEVICE
OTHER

No Results Yet

NCT07126600 | COMPLETED

100 participants

Data Collection for Echocardiography-Based Software Assessment

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-07-11
Completion:: 2025-11-19

Conditions

Atrial Fibrillation
Left Atrial Appendage Closure
Cardiovascular Diseases

Interventions

OTHER

No Results Yet

NCT07117890 | RECRUITING | PHASE2

34 participants

Sunvozertinib Treatment in Untreated Advanced NSCLC With EGFR Uncommon Mutations

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-02-07
Completion:: 2027-02-20

Conditions

Non Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT07111234 | RECRUITING | NA

30 participants

Studying Flavors and Cooling Agents in Oral Nicotine Pouches to Understand User Preferences

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-09-15
Completion:: 2026-12-31

Conditions

Cigarette Smoking-Related Carcinoma

Interventions

DRUG
PROCEDURE
OTHER

No Results Yet

NCT07085754 | RECRUITING | NA

60 participants

Effects of Acute Sleep Deprivation on Individuals With Different APOE Genotypes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-08-08
Completion:: 2025-12-31

Conditions

Sleep
Sleep Deprivation

Interventions

BEHAVIORAL

No Results Yet

NCT07082829 | RECRUITING | PHASE1

208 participants

A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-06-30
Completion:: 2026-06-15

Conditions

Excessive Daytime Sleepiness

Interventions

DRUG
OTHER

No Results Yet

NCT07081880 | RECRUITING

100 participants

Study of the Pathophysiological Mechanisms Involved in the SAPHO Syndrome: Genetic Component and Immune Response

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-07-15
Completion:: 2028-07-15

Conditions

SAPHO Syndrome

Interventions

OTHER

No Results Yet

NCT07080853 | COMPLETED | NA

23 participants

Acute Exercise With Overdressing

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-06-22
Completion:: 2025-04-28

Conditions

Heat Stress, Exertional
Heat Acclimation and Thermotolerance

Interventions

OTHER

No Results Yet

NCT07075861 | RECRUITING

75 participants

The ARTEMIS Data Collection Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-08-10
Completion:: 2028-08-10

Conditions

Aortic Regurgitation Disease

No Results Yet

NCT07063589 | RECRUITING

350 participants

Cannabis Use Patterns Among Young Adults and Associations With Social and Health Outcomes.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-09-16
Completion:: 2027-08-31

Conditions

Cannabis Use

Interventions

OTHER

No Results Yet

NCT07061925 | COMPLETED | PHASE2

169 participants

To Evaluate the Efficacy and Safety of ALC-2203 in Patients With Acute Bronchitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-04-23
Completion:: 2025-11-21

Conditions

Acute Bronchitis

Interventions

DRUG

No Results Yet

NCT07046546 | RECRUITING | NA

10 participants

Thyroid Artery Goitre Embolization Trial A Pilot Study Investigating Thyroid Artery Embolisation as a Treatment for Large Thyroid Nodules

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-09-29
Completion:: 2026-11-30

Conditions

Thyroid Nodule (Benign)
Graves Disease
Goitre

Interventions

PROCEDURE

No Results Yet

NCT07040722 | RECRUITING | NA

12 participants

Effects of the Use of an Immersive Virtual Reality Device on Handwriting in Children Aged 6 to 13 With Handwriting Difficulties ( RVALIGO )

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-10-01
Completion:: 2027-09-01

Conditions

Children With a Need of Rehabilitation for Handwriting

Interventions

OTHER

No Results Yet

NCT07038902 | ACTIVE_NOT_RECRUITING | NA

24 participants

A Comparative Study Between Modified Miniscrew-Assisted Rapid Palatal Expander And Modified Rapid Palatal Expander in Molar Distalization Using Cone- Beam Computed Tomography

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-11-01
Completion:: 2026-12-01

Conditions

Malocclusion, Class I/II
Crowding
Maxillary First Molar Distalization

Interventions

DEVICE

No Results Yet

NCT07034469 | NOT_YET_RECRUITING | NA

150 participants

Air Tamponade Versus Fluorinated Gas Tamponade for Rhegmatogenous Retinal Detachment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2026-03-20
Completion:: 2029-03-20

Conditions

Retinal Detachment Rhegmatogenous

Interventions

PROCEDURE

No Results Yet

NCT07033416 | RECRUITING | NA

60 participants

A Trial Of Approach Bias Modification Training During Treatment For Cocaine Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2026-03-31
Completion:: 2026-10-31

Conditions

Training for Cocaine Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07031934 | COMPLETED

114 participants

Investigation of the Relationships Between Core Muscle Endurance, Pelvic Oscillations and Pelvic Width in Athletes and Sedentaries

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-06-25
Completion:: 2025-06-30

Conditions

Core Muscle Endurance
Athlete
Sedentary

No Results Yet

NCT07029191 | COMPLETED | NA

12 participants

Screening for Alterations in the Autonomic Nervous System

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-11-21
Completion:: 2025-12-12

Conditions

Dysautonomia
ACCUVEIN
Superficial Veins
Sympathetic Nervous System
Standing Test

Interventions

OTHER

No Results Yet

NCT07018856 | RECRUITING

120 participants

Feasibility Study of Novice-Performed Lung Ultrasound for Pneumothorax Detection After Cardiac Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-09-16
Completion:: 2026-09-30

Conditions

Pneumothorax
Cardiac Surgery
Lung Ultrasound
Chest Tube Removal
Postoperative Complications (Cardiopulmonary)

No Results Yet

NCT06992245 | RECRUITING | NA

40 participants

Characterization of Placental Diffusion

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-07-06
Completion:: 2027-12-31

Conditions

Pregnancy in Diabetic
Placenta Diseases

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06991803 | COMPLETED | NA

132 participants

Effects of Different Irrigation Activation Techniques on the Healing of Large Periapical Lesions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-06-01
Completion:: 2024-06-30

Conditions

Periapical Periodontitis
Irrigation Activation
Lasers

Interventions

OTHER

Results Available

NCT06975735 | COMPLETED | NA

108 participants

Does the TAP Block Work Better Than the TFP Block for Relieving Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-05-25
Completion:: 2025-12-15

Conditions

Pain

Interventions

PROCEDURE

No Results Yet

NCT06966323 | RECRUITING

150 participants

Hold me Tight/Let me Go: Effectiveness of a Course to Enhance Parent-adolescent Relationship

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-06-11
Completion:: 2028-02-01

Conditions

Parent Training
Parent Child Relationship
Parent-child Problem

Interventions

BEHAVIORAL

No Results Yet

NCT06942832 | COMPLETED | NA

142 participants

Integrating SPOZ Technology to Support and Enhance the Vitality Acupunch (VA) Exercise Program for Older Adults With Dementia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-04-24
Completion:: 2025-12-18

Conditions

Disease and Dysfunction
Functional Fitness Deterioration
Activities of Daily Living
Instrumental Activities of Daily Living
Sleep Quality

Interventions

OTHER

No Results Yet

NCT06941597 | COMPLETED

40 participants

Comparison of Two Gait Re-training Modalities During a Cardiac Rehabilitation Stay: Benefit of Orienteering Walking

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-04-28
Completion:: 2025-10-05

Conditions

Cardiovascular Diseases (CVD)
Coronary Heart Disease (CHD)
Heart Failure
Congenital Heart Disease

No Results Yet

NCT06941506 | COMPLETED | NA

142 participants

Using SPOZ Technology to Support and Enhance the Vitality Acupunch (VA) Exercise Program for Older Adults With Dementia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-04-23
Completion:: 2025-12-18

Conditions

Cognitive and Behavioral Impairment
Sensory and Perceptual Impairment

Interventions

OTHER

No Results Yet

NCT06939686 | RECRUITING | NA

30 participants

Miro3D Wound Matrix Study for Diabetic Foot Ulcers and Wound Healing

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-11-01
Completion:: 2026-07-31

Conditions

Diabetic Foot Ulcers (DFUs)
Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)

Interventions

DEVICE
OTHER

No Results Yet

NCT06939673 | RECRUITING | NA

20 participants

Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-02-29
Completion:: 2025-12-31

Conditions

Diabetic Foot Ulcers (DFUs)
Venous Leg Ulcers (VLUs)
Pressure Ulcers
Surgical Wound Dehiscence (SWD)
Chronic Wounds
Undermined and Tunneling Wounds

Interventions

DEVICE

No Results Yet

NCT06921824 | COMPLETED | NA

16 participants

Investigating the Acute Effects of Increasing Glucagon Exposure in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-03-31
Completion:: 2025-09-19

Conditions

Glucose Metabolism
Glucagon

Interventions

OTHER

No Results Yet