Effects of Acute Sleep Deprivation on Individuals With Different APOE Genotypes
NCT07085754 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2025-12-24
Summary
This study aims to investigate the effects of 24-hour acute sleep deprivation on plasma Alzheimer's disease biomarkers and multi-omics in individuals with different APOE genotypes, to elucidate the potential role of acute sleep deprivation in AD risk.
Conditions
- Sleep
- Sleep Deprivation
Interventions
- BEHAVIORAL
-
Sleep Deprivation
Sleep deprivation for up to 24 hours with no naps or other sleep periods
Sponsors & Collaborators
-
Yuhui Qiu
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-08-08
- Primary Completion
- 2025-12-31
- Completion
- 2026-12-31
Countries
- China
Study Locations
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