Clinical Trials Updated in 2025

NCT07126600 | COMPLETED

100 participants

Data Collection for Echocardiography-Based Software Assessment

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-07-11
Completion:: 2025-11-19

Conditions

Atrial Fibrillation
Left Atrial Appendage Closure
Cardiovascular Diseases

Interventions

OTHER

No Results Yet

NCT07117890 | RECRUITING | PHASE2

34 participants

Sunvozertinib Treatment in Untreated Advanced NSCLC With EGFR Uncommon Mutations

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-02-07
Completion:: 2027-02-20

Conditions

Non Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT07111234 | RECRUITING | NA

30 participants

Studying Flavors and Cooling Agents in Oral Nicotine Pouches to Understand User Preferences

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-09-15
Completion:: 2026-12-31

Conditions

Cigarette Smoking-Related Carcinoma

Interventions

DRUG
PROCEDURE
OTHER

No Results Yet

NCT07085754 | RECRUITING | NA

60 participants

Effects of Acute Sleep Deprivation on Individuals With Different APOE Genotypes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-08-08
Completion:: 2025-12-31

Conditions

Sleep
Sleep Deprivation

Interventions

BEHAVIORAL

No Results Yet

NCT07082829 | RECRUITING | PHASE1

208 participants

A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-06-30
Completion:: 2026-06-15

Conditions

Excessive Daytime Sleepiness

Interventions

DRUG
OTHER

No Results Yet

NCT07081880 | RECRUITING

100 participants

Study of the Pathophysiological Mechanisms Involved in the SAPHO Syndrome: Genetic Component and Immune Response

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-07-15
Completion:: 2028-07-15

Conditions

SAPHO Syndrome

Interventions

OTHER

No Results Yet

NCT07080853 | COMPLETED | NA

23 participants

Acute Exercise With Overdressing

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-06-22
Completion:: 2025-04-28

Conditions

Heat Stress, Exertional
Heat Acclimation and Thermotolerance

Interventions

OTHER

No Results Yet

NCT07075861 | RECRUITING

75 participants

The ARTEMIS Data Collection Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-08-10
Completion:: 2028-08-10

Conditions

Aortic Regurgitation Disease

No Results Yet

NCT07063589 | RECRUITING

350 participants

Cannabis Use Patterns Among Young Adults and Associations With Social and Health Outcomes.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-09-16
Completion:: 2027-08-31

Conditions

Cannabis Use

Interventions

OTHER

No Results Yet

NCT07061925 | COMPLETED | PHASE2

169 participants

To Evaluate the Efficacy and Safety of ALC-2203 in Patients With Acute Bronchitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-04-23
Completion:: 2025-11-21

Conditions

Acute Bronchitis

Interventions

DRUG

No Results Yet

NCT07046546 | RECRUITING | NA

10 participants

Thyroid Artery Goitre Embolization Trial A Pilot Study Investigating Thyroid Artery Embolisation as a Treatment for Large Thyroid Nodules

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-09-29
Completion:: 2026-11-30

Conditions

Thyroid Nodule (Benign)
Graves Disease
Goitre

Interventions

PROCEDURE

No Results Yet

NCT07040722 | RECRUITING | NA

12 participants

Effects of the Use of an Immersive Virtual Reality Device on Handwriting in Children Aged 6 to 13 With Handwriting Difficulties ( RVALIGO )

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-10-01
Completion:: 2027-09-01

Conditions

Children With a Need of Rehabilitation for Handwriting

Interventions

OTHER

No Results Yet

NCT07038902 | ACTIVE_NOT_RECRUITING | NA

24 participants

A Comparative Study Between Modified Miniscrew-Assisted Rapid Palatal Expander And Modified Rapid Palatal Expander in Molar Distalization Using Cone- Beam Computed Tomography

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-11-01
Completion:: 2026-12-01

Conditions

Malocclusion, Class I/II
Crowding
Maxillary First Molar Distalization

Interventions

DEVICE

No Results Yet

NCT07034469 | NOT_YET_RECRUITING | NA

150 participants

Air Tamponade Versus Fluorinated Gas Tamponade for Rhegmatogenous Retinal Detachment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2026-03-20
Completion:: 2029-03-20

Conditions

Retinal Detachment Rhegmatogenous

Interventions

PROCEDURE

No Results Yet

NCT07033416 | RECRUITING | NA

60 participants

A Trial Of Approach Bias Modification Training During Treatment For Cocaine Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2026-03-31
Completion:: 2026-10-31

Conditions

Training for Cocaine Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07031934 | COMPLETED

114 participants

Investigation of the Relationships Between Core Muscle Endurance, Pelvic Oscillations and Pelvic Width in Athletes and Sedentaries

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-06-25
Completion:: 2025-06-30

Conditions

Core Muscle Endurance
Athlete
Sedentary

No Results Yet

NCT07029191 | COMPLETED | NA

12 participants

Screening for Alterations in the Autonomic Nervous System

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-11-21
Completion:: 2025-12-12

Conditions

Dysautonomia
ACCUVEIN
Superficial Veins
Sympathetic Nervous System
Standing Test

Interventions

OTHER

No Results Yet

NCT07018856 | RECRUITING

120 participants

Feasibility Study of Novice-Performed Lung Ultrasound for Pneumothorax Detection After Cardiac Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-09-16
Completion:: 2026-09-30

Conditions

Pneumothorax
Cardiac Surgery
Lung Ultrasound
Chest Tube Removal
Postoperative Complications (Cardiopulmonary)

No Results Yet

NCT06992245 | RECRUITING | NA

40 participants

Characterization of Placental Diffusion

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-07-06
Completion:: 2027-12-31

Conditions

Pregnancy in Diabetic
Placenta Diseases

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06991803 | COMPLETED | NA

132 participants

Effects of Different Irrigation Activation Techniques on the Healing of Large Periapical Lesions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-06-01
Completion:: 2024-06-30

Conditions

Periapical Periodontitis
Irrigation Activation
Lasers

Interventions

OTHER

Results Available

NCT06975735 | COMPLETED | NA

108 participants

Does the TAP Block Work Better Than the TFP Block for Relieving Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-05-25
Completion:: 2025-12-15

Conditions

Pain

Interventions

PROCEDURE

No Results Yet

NCT06966323 | RECRUITING

150 participants

Hold me Tight/Let me Go: Effectiveness of a Course to Enhance Parent-adolescent Relationship

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-06-11
Completion:: 2028-02-01

Conditions

Parent Training
Parent Child Relationship
Parent-child Problem

Interventions

BEHAVIORAL

No Results Yet

NCT06942832 | COMPLETED | NA

142 participants

Integrating SPOZ Technology to Support and Enhance the Vitality Acupunch (VA) Exercise Program for Older Adults With Dementia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-04-24
Completion:: 2025-12-18

Conditions

Disease and Dysfunction
Functional Fitness Deterioration
Activities of Daily Living
Instrumental Activities of Daily Living
Sleep Quality

Interventions

OTHER

No Results Yet

NCT06941597 | COMPLETED

40 participants

Comparison of Two Gait Re-training Modalities During a Cardiac Rehabilitation Stay: Benefit of Orienteering Walking

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-04-28
Completion:: 2025-10-05

Conditions

Cardiovascular Diseases (CVD)
Coronary Heart Disease (CHD)
Heart Failure
Congenital Heart Disease

No Results Yet

NCT06941506 | COMPLETED | NA

142 participants

Using SPOZ Technology to Support and Enhance the Vitality Acupunch (VA) Exercise Program for Older Adults With Dementia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-04-23
Completion:: 2025-12-18

Conditions

Cognitive and Behavioral Impairment
Sensory and Perceptual Impairment

Interventions

OTHER

No Results Yet

NCT06939686 | RECRUITING | NA

30 participants

Miro3D Wound Matrix Study for Diabetic Foot Ulcers and Wound Healing

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-11-01
Completion:: 2026-07-31

Conditions

Diabetic Foot Ulcers (DFUs)
Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)

Interventions

DEVICE
OTHER

No Results Yet

NCT06939673 | RECRUITING | NA

20 participants

Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-02-29
Completion:: 2025-12-31

Conditions

Diabetic Foot Ulcers (DFUs)
Venous Leg Ulcers (VLUs)
Pressure Ulcers
Surgical Wound Dehiscence (SWD)
Chronic Wounds
Undermined and Tunneling Wounds

Interventions

DEVICE

No Results Yet

NCT06921824 | COMPLETED | NA

16 participants

Investigating the Acute Effects of Increasing Glucagon Exposure in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-03-31
Completion:: 2025-09-19

Conditions

Glucose Metabolism
Glucagon

Interventions

OTHER

No Results Yet

NCT06901544 | COMPLETED

100 participants

Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-03-04
Completion:: 2025-08-01

Conditions

Intra-Abdominal Infections
Intestinal Obstruction
Appendicitis Acute
Perforated Viscus

Results Available

NCT06875115 | COMPLETED | NA

60 participants

Evaluation of the Efficacy of Laser Acupuncture on Uremic Pruritus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-04-09
Completion:: 2024-05-11

Conditions

Uremia

Interventions

DEVICE

Results Available

NCT06853860 | COMPLETED | NA

70 participants

Effects of Hand Massage Applied With Two Different Methods

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-02-15
Completion:: 2025-05-15

Conditions

Angiopathy, Peripheral
Pain, Acute
Reflexology

Interventions

OTHER

No Results Yet

NCT06849947 | NOT_YET_RECRUITING | PHASE2

272 participants

Fulvestrant With Ribociclib Versus Physician's Choice Treatments Recurred After Completion of Adjuvant Cyclin-Dependent Kinase 4/6 Inhibitors in HR+, HER2- Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2026-02-01
Completion:: 2031-06-30

Conditions

Breast Cancer Metastatic

Interventions

DRUG

No Results Yet

NCT06841874 | NO_LONGER_AVAILABLE

Expanded Access Program of Taletrectinib in Patients With Advanced or Metastatic ROS1-Positive NSCLC

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-12-24

Conditions

Lung Neoplasms
Respiratory Tract Neoplasms
Thoracic Neoplasms
Neoplasms by Site
Neoplasms
Lung Diseases
Respiratory Tract Diseases
Carcinoma
Bronchogenic Carcinoma
Non Small Cell Carcinoma of the Lung
ROS1-positive Non-Small Cell Lung Cancer (NSCLC)

Interventions

DRUG

No Results Yet

NCT06827457 | COMPLETED | PHASE1

58 participants

A Study of Safety, Tolerability, PK, and PD of Subcutaneous GenSci120 in Healthy Adults.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-02-20
Completion:: 2025-11-27

Conditions

Autoimmune Disease

Interventions

DRUG

No Results Yet

NCT06814743 | COMPLETED | NA

107 participants

A Mobile Application for Female Athletes With Pelvic Floor Dysfunctions (ACTITUD2.0)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-02-10
Completion:: 2025-06-30

Conditions

Pelvic Floor Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06807580 | RECRUITING | PHASE2

40 participants

Progesterone in Gender Affirming Hormone Therapy Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-05-12
Completion:: 2027-02-28

Conditions

Transgender Women

Interventions

DRUG

No Results Yet

NCT06803602 | ENROLLING_BY_INVITATION | NA

2100 participants

HIFEM Technology for Post-Radical Prostatectomy and Post-Holmium Laser Prostate Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-07-01
Completion:: 2027-03-31

Conditions

Holmium Laser Prostate Surgery
Radical Prostatectomy

Interventions

DEVICE

No Results Yet

NCT06791512 | RECRUITING | PHASE3

166 participants

mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-01-18
Completion:: 2030-12-31

Conditions

Colorectal Cancer (CRC)
pMMR/MSS Adenocarcinoma of the Colon or Rectum

Interventions

DRUG

No Results Yet

NCT06772675 | RECRUITING | NA

13 participants

Vancomycin Reduction Practices (VRP) in the NICU

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-06-02
Completion:: 2027-09-30

Conditions

Antibiotic Stewardship
Neonatal Sepsis, Late-Onset
Vancomycin

Interventions

BEHAVIORAL

No Results Yet

NCT06770972 | RECRUITING | NA

40 participants

Family Foundations for Individuals Pregnant Via ART

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2025-06-11
Completion:: 2026-12-31

Conditions

Assisted Reproductive Technology

Interventions

BEHAVIORAL

No Results Yet