Clinical Trials Updated in 2025

NCT06483854 | RECRUITING | NA

230907 participants

Healer-initiated HIV Counseling and Testing Versus Standard of Care in Rural South Africa

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-11-25
Completion:: 2028-05-01

Conditions

Hiv

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06477302 | RECRUITING

281 participants

Scale of Therapeutic Adherence to Respiratory Rahabilitation for Lung Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-06-23
Completion:: 2026-06-23

Conditions

Lung Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06469723 | ACTIVE_NOT_RECRUITING | NA

300 participants

Protocol for Inpatient Nursing Frailty Assessment (INFA)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-03-03
Completion:: 2025-12-31

Conditions

Functional Status
Frailty

Interventions

OTHER

No Results Yet

NCT06459973 | RECRUITING | PHASE1/PHASE2

252 participants

A Clinical Study of YL205 in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-06-04
Completion:: 2027-07-31

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT06449001 | RECRUITING | PHASE3

6 participants

Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2025-08-11
Completion:: 2027-05-28

Conditions

Paroxysmal Nocturnal Hemoglobinuria
PNH
Extravascular Hemolysis

Interventions

DRUG

No Results Yet

NCT06430229 | COMPLETED | NA

110 participants

Atelectasis Frequency in Different Ventilation Modes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-03-20
Completion:: 2024-06-10

Conditions

Pulmonary Atelectasis
Mechanical Ventilation Complication
General Anesthesia
Lung Ultrasound

Interventions

PROCEDURE

No Results Yet

NCT06400849 | RECRUITING | NA

60 participants

Comparison of the Efficacy of Cryotherapy Combined With Compression in Preventing Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-04-04
Completion:: 2026-12-04

Conditions

Non-metastatic Breast Cancer

Interventions

DEVICE

No Results Yet

NCT06392490 | COMPLETED | NA

48 participants

The Effectiveness of Peer-education Programs for Adolescents Diagnosed With Asthma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2025-03-14
Completion:: 2025-08-12

Conditions

Asthma
Adolescent Behavior
Self Efficacy
Peer Support and Chronic Disease

Interventions

OTHER

No Results Yet

NCT06392477 | RECRUITING | PHASE1

96 participants

A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Relapsed/ Refractory B-Cell Non-Hodgkin Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-07-08
Completion:: 2028-01-21

Conditions

B-cell Non Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT06386978 | COMPLETED | NA

90 participants

Analgesic Efficacy of Transvers Abdominis Plane Block and Transversalis Fascia Plane Block in Cesarean Section

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2025-05-30
Completion:: 2025-09-30

Conditions

Obstetric

Interventions

PROCEDURE

No Results Yet

NCT06380309 | RECRUITING | EARLY_PHASE1

89 participants

A Clinical Study on Evaluating Intravenous Administration of IDOV-SAFE

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-05-06
Completion:: 2025-12-30

Conditions

Advanced Malignant Solid Tumor of Digestive System

Interventions

BIOLOGICAL

No Results Yet

NCT06343220 | COMPLETED

131 participants

Project AWARE 2.0 to Improve Awareness, Willingness and Ability for Research and Enrollment in Clinical Research

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-04-10
Completion:: 2025-12-22

Conditions

Huntington Disease

No Results Yet

NCT06334588 | RECRUITING | NA

160 participants

Understanding the Mechanisms of Autism : an MRI and Social Cognition Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-04-17
Completion:: 2029-04-30

Conditions

Autism Spectrum Disorder

Interventions

DIAGNOSTIC_TEST
DEVICE
OTHER
GENETIC

No Results Yet

NCT06334419 | COMPLETED | PHASE2

10 participants

Placebo-Controlled, Single-Dose Challenge Study of Gaboxadol in Adult Males With Fragile X Syndrome (FXS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-01-29
Completion:: 2025-05-13

Conditions

Fragile X Syndrome

Interventions

DRUG

No Results Yet

NCT06330142 | RECRUITING | NA

22 participants

Hippotherapy Teenager-pediatric Radiotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-06-19
Completion:: 2027-06-19

Conditions

Radiotherapy

Interventions

OTHER

No Results Yet

NCT06286033 | COMPLETED | PHASE1

88 participants

Single and Multiple Ascending Dose Study and Food Effect Study for AG181

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-02-20
Completion:: 2025-10-09

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT06280807 | RECRUITING

300 participants

Observation of Environment and Reproductive-Endocrine Effects

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-07-01
Completion:: 2039-03-28

Conditions

Hypogonadism
Hypergonadism
Precocious Puberty
Late Puberty
Amenorrhea

No Results Yet

NCT06269367 | COMPLETED | NA

20 participants

NewGait: A Low-Cost Rehabilitation System to Improve Post-Stroke Gait (Biomechanical Adaptations)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-04-01
Completion:: 2024-12-09

Conditions

Stroke

Interventions

OTHER

Results Available

NCT06268860 | COMPLETED | PHASE1

240 participants

A Study to Assess Bioavailability of Rocatinlimab (AMG 451) Vial and Prefilled Syringe in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-02-15
Completion:: 2024-08-30

Conditions

Atopic Dermatitis

Interventions

DRUG
COMBINATION_PRODUCT

No Results Yet

NCT06268808 | COMPLETED | NA

90 participants

Initiation of Continuous Glucose Monitoring in Adults With Type 2 Diabetes Treated With Basal Insulin, in Italy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-07-19
Completion:: 2025-09-24

Conditions

Type 2 Diabetes Treated With Insulin

Interventions

DEVICE

No Results Yet

NCT06250855 | COMPLETED

105 participants

Observational Prospective Clinical Investigation on Monofocal Toric Intraocular Lens

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-04-24
Completion:: 2024-10-27

Conditions

Cataract
Astigmatism

Interventions

DEVICE

No Results Yet

NCT06243783 | RECRUITING | NA

68 participants

Impact of Stress on Brain Energy Metabolism

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-03-01
Completion:: 2028-02-29

Conditions

Stress

Interventions

BEHAVIORAL

No Results Yet

NCT06239948 | COMPLETED | NA

40 participants

The Brain Symphony For Post-Stroke Rehabilitation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2018-01-01
Completion:: 2020-12-31

Conditions

Stroke

Interventions

OTHER

No Results Yet

NCT06232746 | COMPLETED | NA

9 participants

Magnetic Jejuno-Ileal Diversion Study ("MJI Study")

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-02-13
Completion:: 2024-09-24

Conditions

Obesity
Type 2 Diabetes

Interventions

DEVICE

No Results Yet

NCT06228768 | COMPLETED | NA

50 participants

Acupressure for Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Patients With Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-03-06
Completion:: 2025-11-16

Conditions

Postmenopausal
Breast Cancer

Interventions

OTHER

No Results Yet

NCT06227429 | WITHDRAWN

0 participants

A Non-interventional, Post-Marketing Study to Describe Outcome of Nitisinone Treatment in HT-1 Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2025-09-30
Completion:: 2027-06-30

Conditions

Hereditary Tyrosinemia, Type I

Interventions

DRUG

No Results Yet

NCT06206408 | COMPLETED | PHASE3

410 participants

A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Japanese Women Going Through Menopause

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-02-16
Completion:: 2025-10-22

Conditions

Hot Flashes

Interventions

DRUG

No Results Yet

NCT06178952 | RECRUITING | NA

102 participants

Transcranial Pulse Stimulation (TPS) in Post-COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-01-08
Completion:: 2027-01-31

Conditions

Post-COVID-19 Syndrome
Fatigue

Interventions

DEVICE

No Results Yet

NCT06153810 | COMPLETED | NA

26 participants

Efficacy of AesyBite Active in Reducing Sleep Bruxism Activity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-11-17
Completion:: 2025-11-07

Conditions

Sleep Bruxism

Interventions

DEVICE

No Results Yet

NCT06138522 | RECRUITING

65 participants

Qualitative Study on the Perception of Changes in the Psychotherapy of Traumatized Young People

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-11-30
Completion:: 2028-05-31

Conditions

Post-traumatic Stress Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06125197 | ACTIVE_NOT_RECRUITING | PHASE1

22 participants

Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Refractory Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-07-23
Completion:: 2026-01-30

Conditions

Lung Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT06120881 | RECRUITING | EARLY_PHASE1

20 participants

Precision Dosing of Metformin in Youth With T2D

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-04-25
Completion:: 2026-12-31

Conditions

Type 2 Diabetes

Interventions

DRUG

No Results Yet

NCT06120712 | COMPLETED | PHASE1/PHASE2

18 participants

A Study of GC101 TIL in Advanced Melanoma (BZ)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-11-08
Completion:: 2024-11-12

Conditions

Tumor Infiltrating Lymphocytes
Safety
Melanoma
Efficacy
Adverse Drug Event

Interventions

BIOLOGICAL

No Results Yet

NCT06105957 | RECRUITING | NA

616 participants

Optimal Digital Weight Loss Treatment for Rural Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-01-03
Completion:: 2027-02-28

Conditions

Overweight and Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT06101095 | ACTIVE_NOT_RECRUITING | PHASE4

69 participants

A Study Assessing Esophageal Function and Remodeling With Dupilumab Compared With Placebo for 24 Weeks Followed by 104 Weeks Open Label in Adult Participants With EoE (REMOdeling With Dupilumab in Eosinophilic Esophagitis Long-term Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-11-29
Completion:: 2025-11-05

Conditions

Eosinophilic Oesophagitis

Interventions

DRUG

No Results Yet

NCT06078774 | COMPLETED | NA

10 participants

Redesigning Pediatric Primary Care Obesity Treatment: Virtual House Calls

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-01-24
Completion:: 2024-08-16

Conditions

Obesity, Pediatric

Interventions

BEHAVIORAL

Results Available

NCT06064110 | COMPLETED | NA

185 participants

Pictou County PEP: A 6-Month, Home-Based, Personal Empowerment Program for Adults With a Chronic Medical Condition Living in Pictou County

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-11-24
Completion:: 2025-05-14

Conditions

Chronic Condition

Interventions

BEHAVIORAL

No Results Yet

NCT06063395 | COMPLETED

30 participants

Study of the Size of the Operating Fields Depending on the Morphology of the Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-05-15
Completion:: 2025-12-17

Conditions

Open Surgery on the Abdominal Aorta

Interventions

PROCEDURE

No Results Yet

NCT06058637 | COMPLETED | NA

234 participants

iSCREEN-study: Online Nurse-assisted Eye-screening in Home Healthcare

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-03-23
Completion:: 2025-11-03

Conditions

Eye Diseases

Interventions

DEVICE

No Results Yet

NCT06047353 | RECRUITING | NA

48 participants

Community Health Advocates for Motivating PAP Use in Our Neighborhoods.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-09-29
Completion:: 2027-12-01

Conditions

Obstructive Sleep Apnea

Interventions

BEHAVIORAL
DEVICE

No Results Yet