Clinical Trials Updated in 2025

NCT06280807 | RECRUITING

300 participants

Observation of Environment and Reproductive-Endocrine Effects

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-07-01
Completion:: 2039-03-28

Conditions

Hypogonadism
Hypergonadism
Precocious Puberty
Late Puberty
Amenorrhea

No Results Yet

NCT06269367 | COMPLETED | NA

20 participants

NewGait: A Low-Cost Rehabilitation System to Improve Post-Stroke Gait (Biomechanical Adaptations)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-04-01
Completion:: 2024-12-09

Conditions

Stroke

Interventions

OTHER

Results Available

NCT06268860 | COMPLETED | PHASE1

240 participants

A Study to Assess Bioavailability of Rocatinlimab (AMG 451) Vial and Prefilled Syringe in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-02-15
Completion:: 2024-08-30

Conditions

Atopic Dermatitis

Interventions

DRUG
COMBINATION_PRODUCT

No Results Yet

NCT06268808 | COMPLETED | NA

90 participants

Initiation of Continuous Glucose Monitoring in Adults With Type 2 Diabetes Treated With Basal Insulin, in Italy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-07-19
Completion:: 2025-09-24

Conditions

Type 2 Diabetes Treated With Insulin

Interventions

DEVICE

No Results Yet

NCT06250855 | COMPLETED

105 participants

Observational Prospective Clinical Investigation on Monofocal Toric Intraocular Lens

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-04-24
Completion:: 2024-10-27

Conditions

Cataract
Astigmatism

Interventions

DEVICE

No Results Yet

NCT06243783 | RECRUITING | NA

68 participants

Impact of Stress on Brain Energy Metabolism

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-03-01
Completion:: 2028-02-29

Conditions

Stress

Interventions

BEHAVIORAL

No Results Yet

NCT06239948 | COMPLETED | NA

40 participants

The Brain Symphony For Post-Stroke Rehabilitation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2018-01-01
Completion:: 2020-12-31

Conditions

Stroke

Interventions

OTHER

No Results Yet

NCT06232746 | COMPLETED | NA

9 participants

Magnetic Jejuno-Ileal Diversion Study ("MJI Study")

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-02-13
Completion:: 2024-09-24

Conditions

Obesity
Type 2 Diabetes

Interventions

DEVICE

No Results Yet

NCT06228768 | COMPLETED | NA

50 participants

Acupressure for Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Patients With Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-03-06
Completion:: 2025-11-16

Conditions

Postmenopausal
Breast Cancer

Interventions

OTHER

No Results Yet

NCT06227429 | WITHDRAWN

0 participants

A Non-interventional, Post-Marketing Study to Describe Outcome of Nitisinone Treatment in HT-1 Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2025-09-30
Completion:: 2027-06-30

Conditions

Hereditary Tyrosinemia, Type I

Interventions

DRUG

No Results Yet

NCT06206408 | COMPLETED | PHASE3

410 participants

A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Japanese Women Going Through Menopause

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-02-16
Completion:: 2025-10-22

Conditions

Hot Flashes

Interventions

DRUG

No Results Yet

NCT06178952 | RECRUITING | NA

102 participants

Transcranial Pulse Stimulation (TPS) in Post-COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-01-08
Completion:: 2027-01-31

Conditions

Post-COVID-19 Syndrome
Fatigue

Interventions

DEVICE

No Results Yet

NCT06153810 | COMPLETED | NA

26 participants

Efficacy of AesyBite Active in Reducing Sleep Bruxism Activity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-11-17
Completion:: 2025-11-07

Conditions

Sleep Bruxism

Interventions

DEVICE

No Results Yet

NCT06138522 | RECRUITING

65 participants

Qualitative Study on the Perception of Changes in the Psychotherapy of Traumatized Young People

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-11-30
Completion:: 2028-05-31

Conditions

Post-traumatic Stress Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06125197 | ACTIVE_NOT_RECRUITING | PHASE1

22 participants

Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Refractory Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-07-23
Completion:: 2026-01-30

Conditions

Lung Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT06120881 | RECRUITING | EARLY_PHASE1

20 participants

Precision Dosing of Metformin in Youth With T2D

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-04-25
Completion:: 2026-12-31

Conditions

Type 2 Diabetes

Interventions

DRUG

No Results Yet

NCT06120712 | COMPLETED | PHASE1/PHASE2

18 participants

A Study of GC101 TIL in Advanced Melanoma (BZ)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-11-08
Completion:: 2024-11-12

Conditions

Tumor Infiltrating Lymphocytes
Safety
Melanoma
Efficacy
Adverse Drug Event

Interventions

BIOLOGICAL

No Results Yet

NCT06105957 | RECRUITING | NA

616 participants

Optimal Digital Weight Loss Treatment for Rural Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-01-03
Completion:: 2027-02-28

Conditions

Overweight and Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT06101095 | ACTIVE_NOT_RECRUITING | PHASE4

69 participants

A Study Assessing Esophageal Function and Remodeling With Dupilumab Compared With Placebo for 24 Weeks Followed by 104 Weeks Open Label in Adult Participants With EoE (REMOdeling With Dupilumab in Eosinophilic Esophagitis Long-term Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-11-29
Completion:: 2025-11-05

Conditions

Eosinophilic Oesophagitis

Interventions

DRUG

No Results Yet

NCT06078774 | COMPLETED | NA

10 participants

Redesigning Pediatric Primary Care Obesity Treatment: Virtual House Calls

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-01-24
Completion:: 2024-08-16

Conditions

Obesity, Pediatric

Interventions

BEHAVIORAL

Results Available

NCT06064110 | COMPLETED | NA

185 participants

Pictou County PEP: A 6-Month, Home-Based, Personal Empowerment Program for Adults With a Chronic Medical Condition Living in Pictou County

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-11-24
Completion:: 2025-05-14

Conditions

Chronic Condition

Interventions

BEHAVIORAL

No Results Yet

NCT06063395 | COMPLETED

30 participants

Study of the Size of the Operating Fields Depending on the Morphology of the Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-05-15
Completion:: 2025-12-17

Conditions

Open Surgery on the Abdominal Aorta

Interventions

PROCEDURE

No Results Yet

NCT06058637 | COMPLETED | NA

234 participants

iSCREEN-study: Online Nurse-assisted Eye-screening in Home Healthcare

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-03-23
Completion:: 2025-11-03

Conditions

Eye Diseases

Interventions

DEVICE

No Results Yet

NCT06047353 | RECRUITING | NA

48 participants

Community Health Advocates for Motivating PAP Use in Our Neighborhoods.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-09-29
Completion:: 2027-12-01

Conditions

Obstructive Sleep Apnea

Interventions

BEHAVIORAL
DEVICE

No Results Yet

NCT06027242 | RECRUITING | NA

120 participants

Oral Supplementation of Glutamine on Gastric Cancer Patients After Gastrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-02-21
Completion:: 2026-08-30

Conditions

Gastric Cancer
Immunonutrition
Gastrostomy

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05981547 | ACTIVE_NOT_RECRUITING

400 participants

Patterns and Glycaemic Endpoints for Diagnosing Gestational Diabetes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-11-22
Completion:: 2026-06-21

Conditions

Gestational Diabetes

Interventions

DEVICE

No Results Yet

NCT05941286 | COMPLETED | NA

533 participants

Effect of Continuous Glucose Monitoring System Alerts on Diabetes Management in the Hospital

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-04-18
Completion:: 2024-12-16

Conditions

Diabetes Mellitus

Interventions

DEVICE

No Results Yet

NCT05916274 | COMPLETED | NA

40 participants

Exploration of the Activity of DNA Located Outside of Cellular Nucleus to Amplify Inflammation in Inflammatory Bowel Disease in Children Through Biological Pathway Cyclic GMP-AMP Synthase (cGAS) - Stimulator of Interferon Genes (STING)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-05-31
Completion:: 2024-02-29

Conditions

Inflammatory Bowel Diseases
Crohn Disease
Ulcerative Colitis

Interventions

BIOLOGICAL
PROCEDURE

No Results Yet

NCT05915468 | COMPLETED

306 participants

Large De-NOVo Coronary artEry Disease Treated With Sirolimus Drug Eluting Balloon (LOVE DEB)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-07-12
Completion:: 2025-12-11

Conditions

Coronary Artery Disease

No Results Yet

NCT05913882 | RECRUITING | NA

34 participants

Combined Respiratory Training in Persons With ALS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-08-22
Completion:: 2026-09-30

Conditions

ALS
Respiratory Insufficiency
Dysphagia

Interventions

DEVICE

No Results Yet

NCT05910606 | ACTIVE_NOT_RECRUITING | NA

92 participants

Strong Foundations 2.0: A Digitally Delivered Fall Prevention Program.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-09-01
Completion:: 2026-07-16

Conditions

Fall Prevention
Bone Health
Balance

Interventions

BEHAVIORAL

No Results Yet

NCT05905302 | COMPLETED | NA

15 participants

The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-08-15
Completion:: 2024-09-20

Conditions

Parkinson Disease
Deep Brain Stimulation

Interventions

OTHER

Results Available

NCT05891119 | COMPLETED | EARLY_PHASE1

21 participants

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-06-03
Completion:: 2024-08-28

Conditions

Atopic Dermatitis

Interventions

DIETARY_SUPPLEMENT
DRUG

No Results Yet

NCT05854485 | COMPLETED | NA

24 participants

Robot-Aided Assessment and Rehabilitation of Upper Extremity Function After Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-09-06
Completion:: 2025-05-30

Conditions

Stroke

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05830760 | WITHDRAWN | NA

0 participants

Expression of Sodium-glucose Co-transporter 2 in Human Heart

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-06-30
Completion:: 2025-10-31

Conditions

Aortic Valve Stenosis

Interventions

BIOLOGICAL

No Results Yet

NCT05827926 | COMPLETED | PHASE1/PHASE2

1758 participants

A Study of mRNA-based Influenza and SARS-CoV-2 (COVID-19) Multi-component Vaccines in Healthy Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-04-14
Completion:: 2024-12-03

Conditions

SARS-CoV-2
Influenza

Interventions

BIOLOGICAL

Results Available

NCT05803720 | COMPLETED | NA

59 participants

HIV Provider Intervention to Address Intersectional Stigma and Medical Mistrust

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-04-01
Completion:: 2024-03-31

Conditions

Stigma, Social

Interventions

BEHAVIORAL

Results Available

NCT05763901 | COMPLETED | NA

151 participants

IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2021-04-01
Completion:: 2024-05-16

Conditions

Genu Varum
Genu Valgus
Flat Feet
Cavus Foot
Scoliosis Idiopathic
Varus; Talipes
Valgus, Talipes
Laxity of Ligament
Hyperlordosis
Hyperkyphosis
Angular Limb Deformity

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05746845 | COMPLETED

100 participants

Implication of 5-HT7 Receptor in Inflammatory Mechanisms in Multiple Sclerosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-23
Start Date:: 2023-03-06
Completion:: 2024-07-01

Conditions

Healthy
Multiple Sclerosis

Interventions

BIOLOGICAL

No Results Yet

NCT05696132 | TERMINATED | PHASE2

1 participants

Evaluation of the Decolonization Rate and Acceptance of a Complete Nasal Decolonization Kit With Povidone Iodine for MRSA Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-23
Start Date:: 2024-11-21
Completion:: 2025-12-04

Conditions

MRSA

Interventions

DRUG

No Results Yet