Clinical Trials Updated in 2025

NCT05320367 | NOT_YET_RECRUITING | PHASE1/PHASE2

80 participants

A Study of Inhaled Cannabidiol in Healthy Occasional Cannabis Users

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2026-09-30
Completion:: 2027-10-31

Conditions

Cannabis

Interventions

DRUG

No Results Yet

NCT05318924 | COMPLETED | PHASE1/PHASE2

26 participants

Effects of Ghrelin Administration on Dopamine and Effort

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-02-21
Completion:: 2024-08-06

Conditions

Major Depressive Disorder

Interventions

DRUG
OTHER

No Results Yet

NCT05288543 | TERMINATED | PHASE1

63 participants

A Study of Orally Administered IPG7236 in Healthy Adult Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-04-07
Completion:: 2023-03-31

Conditions

Atopic Dermatitis

Interventions

DRUG
OTHER

No Results Yet

NCT05284513 | ENROLLING_BY_INVITATION | NA

532 participants

Collaborative Approach to Reach Everyone With Familial Hypercholesterolemia (CARE-FH)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-09-09
Completion:: 2027-01-31

Conditions

Familial Hypercholesterolemia

Interventions

BEHAVIORAL

No Results Yet

NCT05258435 | ACTIVE_NOT_RECRUITING

131 participants

Long-term Assessment of the Safety and Performance of the NuVasive Simplify Disc

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-02-09
Completion:: 2028-04-30

Conditions

Cervical Disc Disease
Degenerative Disc Disease

Interventions

DEVICE

No Results Yet

NCT05218655 | COMPLETED | PHASE3

101 participants

A Safety Study for Previously Treated Vatiquinone (PTC743) Participants With Inherited Mitochondrial Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-06-22
Completion:: 2025-04-15

Conditions

Inherited Mitochondrial Disease

Interventions

DRUG

Results Available

NCT05202093 | COMPLETED | NA

129 participants

Efficacy of Two Sonic Toothbrushes in Reducing Extrinsic Tooth Stain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-03-05
Completion:: 2022-07-15

Conditions

Tooth Bleaching

Interventions

DEVICE

Results Available

NCT05193396 | RECRUITING | PHASE4

100 participants

Hydrocortisone and Placebo in Patients With Symptoms of Adrenal Insufficiency After Cessation of Glucocorticoid Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-02-01
Completion:: 2026-01-31

Conditions

Adrenal Insufficiency
Polymyalgia Rheumatica (PMR)
Giant Cell Arteritis (GCA)

Interventions

DRUG

No Results Yet

NCT05187429 | RECRUITING | PHASE1/PHASE2

42 participants

Low Dose Nivolumab in Adults Living With HIV on Antiretroviral Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-01-24
Completion:: 2029-01-31

Conditions

HIV I Infection

Interventions

DRUG

No Results Yet

NCT05174780 | COMPLETED | NA

159 participants

Myopia Control With a Innovative Spectacle Lens

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-12-29
Completion:: 2025-10-20

Conditions

Myopia

Interventions

DEVICE

No Results Yet

NCT05173844 | COMPLETED | NA

128 participants

Digital Sleep Therapy for Older Adults With Cognitive Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-11-10
Completion:: 2025-07-01

Conditions

Insomnia Type; Sleep Disorder
Cognitive Impairment

Interventions

OTHER

No Results Yet

NCT05171686 | COMPLETED | PHASE4

49 participants

Diuretics and Volume Overload in Early CKD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2023-02-01
Completion:: 2025-10-02

Conditions

Chronic Kidney Disease
Hypertension

Interventions

DRUG

No Results Yet

NCT05123196 | COMPLETED | PHASE2

156 participants

Exploratory Study of MT-8554 in Subjects With Painful Diabetic Peripheral Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-11-16
Completion:: 2022-11-01

Conditions

Painful Diabetic Peripheral Neuropathy

Interventions

DRUG

No Results Yet

NCT05120570 | COMPLETED | PHASE1/PHASE2

16 participants

PTCy + Sirolimus/VIC-1911 as GVHD Prophylaxis in Myeloablative PBSC Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-03-17
Completion:: 2024-09-19

Conditions

Acute Leukemia
Myelodysplastic Syndromes
Myeloproliferative Neoplasm
Lymphoma

Interventions

DRUG

Results Available

NCT05117307 | NOT_YET_RECRUITING | NA

60 participants

Comparison of Transversalis Fascia Plane Block and Erector Spinae Plane Blocks in Cesarean Section

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2025-12-20
Completion:: 2026-06-15

Conditions

Pain
Postoperative Pain

Interventions

DRUG

No Results Yet

NCT05089227 | RECRUITING | PHASE2

72 participants

Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-02-03
Completion:: 2028-08-31

Conditions

Prolonged Anticoagulation
Venous Thromboembolic Disease
Autoimmune Hemolytic Anemia

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT05080465 | COMPLETED | PHASE3

700 participants

Long Term Follow up Mesenchymal Stem Cell Therapy for Patients Virus-related Liver Cirrhosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2018-12-02
Completion:: 2024-10-07

Conditions

Liver Cirrhosis

Interventions

BIOLOGICAL

No Results Yet

NCT05074277 | COMPLETED | NA

20 participants

Skeletal Response to Simulated Night Shift

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-02-08
Completion:: 2025-12-18

Conditions

Osteoporosis
Circadian Rhythm Sleep Disorder, Shift Work Type

Interventions

BEHAVIORAL

No Results Yet

NCT05067569 | COMPLETED | NA

270 participants

App-delivered Sleep ThERapy for Older Individuals With Insomnia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-10-01
Completion:: 2025-01-31

Conditions

Insomnia

Interventions

BEHAVIORAL

No Results Yet

NCT05066711 | ENROLLING_BY_INVITATION

75 participants

NuVasive® ACP System Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-05-22
Completion:: 2026-09-30

Conditions

Cervical Spondylosis
Cervical Radiculopathy
Cervical Myelopathy
Cervical Disc Disease
Cervical Stenosis
Cervical Disc Herniation
Cervical Spine Disease

No Results Yet

NCT05039151 | COMPLETED

26 participants

Interstitial Fluid Composition in Patients With Septic Versus Non-septic Shock: an Exploratory Pilot Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-01-25
Completion:: 2025-07-19

Conditions

Interstitial Liquid
Septic Shock

Interventions

BIOLOGICAL

No Results Yet

NCT05014204 | COMPLETED | NA

20 participants

Safety and Feasibility of Novel Therapy for Duodenal Mucosal Regeneration for Type II Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-10-29
Completion:: 2024-05-29

Conditions

Diabetes
Diabetes Type 2
Diabetes Mellitus, Type 2
Glucose Metabolism Disorders
Metabolic Disease
Endocrine System Diseases
Diabetes Mellitus

Interventions

DEVICE

Results Available

NCT04996628 | RECRUITING | NA

150 participants

Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-01-04
Completion:: 2026-06-30

Conditions

Chronic Pancreatitis
Chronic Pain

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04965298 | RECRUITING | PHASE3

298 participants

Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-06-16
Completion:: 2026-02-28

Conditions

Idiopathic Pulmonary Fibrosis

Interventions

DRUG
OTHER

No Results Yet

NCT04953286 | COMPLETED | NA

55 participants

Ocular Surface Metabolo-lipidomics in Lateral Amyotrophic Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-09-17
Completion:: 2023-09-30

Conditions

Amyotrophic Lateral Sclerosis

Interventions

OTHER

No Results Yet

NCT04936178 | COMPLETED | PHASE1

258 participants

A Study of NB003 in Patients With Advanced Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-08-06
Completion:: 2025-08-01

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT04920604 | COMPLETED | NA

172 participants

Anesthetic and Perioperative Risk Assessment Before Programmed Surgery: Anesthetic Teleconsultation Versus Face-to-face Anesthesia Consultation.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-05-20
Completion:: 2022-04-21

Conditions

Telemedicine
Anesthesia
Consultation, Remote

Interventions

OTHER

No Results Yet

NCT04916522 | ACTIVE_NOT_RECRUITING | PHASE2

150 participants

The COlchicine HypERtENsion Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-08-10
Completion:: 2026-01-31

Conditions

Hypertension

Interventions

DRUG

No Results Yet

NCT04879277 | COMPLETED | NA

40 participants

Study of Low-grade Systemic Inflammation in Adult Patients With Phenylketonuria

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-05-26
Completion:: 2021-08-25

Conditions

Phenylketonuria

Interventions

BIOLOGICAL

No Results Yet

NCT04854278 | RECRUITING

400 participants

Introduction of an Operating Room Black Box to Identify, Analyse and Prevent Errors in the Vascular Hybrid Room

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2019-02-19
Completion:: 2027-12-31

Conditions

Patient Safety
Endovascular Procedures
Quality Improvement

Interventions

OTHER

No Results Yet

NCT04847089 | COMPLETED | NA

16 participants

Motor Imagery BCI Rehabilitation After Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-04-14
Completion:: 2025-07-01

Conditions

Stroke
Hemiparesis

Interventions

DEVICE

No Results Yet

NCT04833556 | COMPLETED

649 participants

Perioperative Outcomes of Postpartum Hemorrhage in Patients Undergoing Cesarean Delivery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-04-22
Completion:: 2024-12-31

Conditions

Cesarean Section Complications
Postpartum Hemorrhage
Anesthesia Complication
Blood Transfusion Complication
Uterine Atony With Hemorrhage

No Results Yet

NCT04800341 | COMPLETED

233 participants

Long-term Follow-up in Patients Included in the European Sleep Apnea Data Base (ESADA)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-05-12
Completion:: 2022-06-06

Conditions

Sleep Apnea

Interventions

OTHER

No Results Yet

NCT04770571 | ENROLLING_BY_INVITATION

150 participants

Posterior Cervical Fixation Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-05-10
Completion:: 2026-09-30

Conditions

Degenerative Disc Disease
Craniocervical Injuries
Cervical Radiculopathy
Cervical Disc Disease
Cervical Fusion
Cervical Spine Disease
Cervical Myelopathy
Cervical Instabilities Spine
Thoracic Injury

Interventions

DEVICE

No Results Yet

NCT04768777 | NOT_YET_RECRUITING | NA

30 participants

Behavioral Intervention for Physical Activity and Sexual Dysfunction in Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2026-12-01
Completion:: 2026-12-01

Conditions

Multiple Sclerosis, Relapsing-Remitting
Sexual Dysfunction

Interventions

BEHAVIORAL

No Results Yet

NCT04752696 | COMPLETED | PHASE2

41 participants

Onvansertib in Combination With Nanoliposomal Irinotecan, Leucovorin, and Fluorouracil for Second-Line Treatment of Participants With Metastatic Pancreatic Ductal Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-05-25
Completion:: 2024-12-24

Conditions

Pancreatic Ductal Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT04751578 | ACTIVE_NOT_RECRUITING | NA

15 participants

Abdominal Aortic Aneurysm Sac Healing and Prevention of Endoleaks - Netherlands

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-07-13
Completion:: 2022-04-13

Conditions

Abdominal Aortic Aneurysm

Interventions

DEVICE

No Results Yet

NCT04738812 | COMPLETED | PHASE3

1330 participants

Determination of Adequate Tuberculosis Regimen in Patients Hospitalized With HIV-associated Severe Immune Suppression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2022-04-21
Completion:: 2025-11-12

Conditions

Tuberculosis
HIV-1-infection
Immuno-Deficiency

Interventions

DRUG

No Results Yet

NCT04725786 | COMPLETED | NA

30 participants

Clinical Relevance of Thoracic Echography for the Early Diagnosis of Interstitial Lung Disease in Systemic Scleroderma - Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-03-17
Completion:: 2022-06-08

Conditions

Systemic Sclerosis

Interventions

OTHER

No Results Yet

NCT04704401 | TERMINATED

321 participants

Long-Term Follow-up in Patients Included in the Meta-analysis "Sleep Apnea Syndrome and Arterial Stiffness"

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-22
Start Date:: 2021-01-13
Completion:: 2022-08-29

Conditions

Sleep Apnea

Interventions

OTHER

No Results Yet