Clinical Trials

NCT06425861 | COMPLETED | PHASE1

60 participants

A First in Human Trial Evaluating THB335 in Healthy Participants

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2024-05-02

Completion:

2024-12-18

Conditions

• Healthy

Interventions

• DRUG

No Results Yet

NCT06359665 | ENROLLING_BY_INVITATION | PHASE1

100 participants

Oral Curcumin for the Treatment of Pain of Thumb Base Joint (CMC) Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2025-02-01

Completion:

2026-02-28

Conditions

• Arthritis of Carpometacarpal Joint of Left Thumb
• Arthritis of Carpometacarpal Joint of Right Thumb

Interventions

• DRUG

No Results Yet

NCT06334952 | RECRUITING | NA

60 participants

Efficacy of Personnalized Transcranial Direct Current Electrical Stimulation (tDCS) in Drug-resistant Epileptic

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2024-12-18

Completion:

2026-12-18

Conditions

• Epilepsy
• Drug Resistant Epilepsy

Interventions

• DEVICE

No Results Yet

NCT06311487 | ACTIVE_NOT_RECRUITING | NA

20 participants

Time and Nutrient-Dependent Effects of Aerobic Exercise on Metabolism in Adults (TANDEM Study)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2024-04-15

Completion:

2026-03-01

Conditions

• Overweight and Obesity
• Healthy

Interventions

• BEHAVIORAL

No Results Yet

NCT06300229 | COMPLETED | PHASE1/PHASE2

42 participants

NAPO - Novel Approach for Oligospermia

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2024-03-01

Completion:

2025-01-29

Conditions

• Infertility, Male

Interventions

• DRUG

No Results Yet

NCT06292156 | COMPLETED | NA

68 participants

tACS Treatment for Cognitive Impairments in Methamphetamine Addicts

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2023-12-30

Completion:

2024-12-30

Conditions

• Methamphetamine Abuse

Interventions

• DEVICE

No Results Yet

NCT06287567 | COMPLETED | PHASE2

17 participants

Lusutrombopag in the Treatment of Immune Thrombocytopenia (ITP)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2024-04-17

Completion:

2024-11-13

Conditions

• Idiopathic Thrombocytopenic Purpura
• Immune Thrombocytopenia

Interventions

• DRUG

No Results Yet

NCT06285591 | COMPLETED | PHASE2

160 participants

Lactobacillus Reuteri Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2024-03-01

Completion:

2025-01-01

Conditions

• Head and Neck Malignant Tumors

Interventions

• DRUG
• RADIATION

No Results Yet

NCT06277999 | COMPLETED

7 participants

C.Difficile Observational Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-19

Start Date:

2024-04-22

Completion:

2024-12-17

Conditions

• Clostridium Infections

No Results Yet

NCT06262139 | RECRUITING | PHASE1/PHASE2

12 participants

Evaluation of a Targeted Magnetic Resonance Imaging Contrast Agent in Prostate Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2024-07-25

Completion:

2026-12-31

Conditions

• MRI Scan

Interventions

• DRUG

No Results Yet

NCT06256991 | RECRUITING | PHASE4

44 participants

Potassium Correction for RAAS Optimization in Chronic Kidney Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2024-04-01

Completion:

2026-12-31

Conditions

• Chronic Kidney Diseases
• Hyperkalemia
• Hypertension

Interventions

• DRUG

No Results Yet

NCT06253221 | ACTIVE_NOT_RECRUITING | PHASE3

44 participants

A Study to Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2024-04-17

Completion:

2025-11-25

Conditions

• Cardiomyopathy, Hypertrophic

Interventions

• DRUG

No Results Yet

NCT06235580 | RECRUITING

1000 participants

Genotype-phenotype Characterization Study on Genetic Diseases With Immune and Neurological Dysfunctions

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-19

Start Date:

2015-12-28

Completion:

2030-12-27

Conditions

• Genetic Diseases
• Immune Dysfunction
• Neurological Disease
• Autoimmune Diseases

Interventions

• OTHER

No Results Yet

NCT06231472 | COMPLETED | NA

110 participants

Effect of Preoperative Fluid Therapy on Post-induction Hypotension

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2022-05-01

Completion:

2023-11-01

Conditions

• Hypovolemia

Interventions

• OTHER

No Results Yet

NCT06228703 | COMPLETED | NA

26 participants

The Effects of Different Flow Settings on Lung Impedance

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2024-05-19

Completion:

2024-10-15

Conditions

• Healthy

Interventions

• DEVICE

Results Available

NCT06226844 | RECRUITING | NA

54 participants

Can the BeatMove Device Help Patients With Obliterative Arterial Disease of the Lower Limbs?

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2024-06-14

Completion:

2027-11-01

Conditions

• Atheromatous
• Lower Limb Ischemia
• Artery Disease

Interventions

• DEVICE

No Results Yet

NCT06225271 | ACTIVE_NOT_RECRUITING | NA

934 participants

Effects of the Combined Intervention of Exercise, Fruit, and Vitamin Supplementation on Frailty in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2024-03-08

Completion:

2025-04-15

Conditions

• Frailty

Interventions

• BEHAVIORAL

No Results Yet

NCT06111937 | COMPLETED | NA

148 participants

Time Interval After Gastric Emptying and Quality of Bowel Cleansing

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2023-11-01

Completion:

2024-06-30

Conditions

• Colonoscopy

Interventions

• OTHER

No Results Yet

NCT06110754 | COMPLETED | NA

45 participants

Development and Adaptation of I-STRONG for SCD

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2023-06-08

Completion:

2024-06-14

Conditions

• Sickle Cell Disease

Interventions

• BEHAVIORAL

Results Available

NCT06088784 | COMPLETED | PHASE1

76 participants

A Study Assessing the Safety of Oral ATH-399A in Healthy Adult Participants

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2023-09-19

Completion:

2024-04-24

Conditions

• Healthy Volunteers

Interventions

• DRUG

Results Available

NCT06085742 | RECRUITING | PHASE2

25 participants

BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2023-11-22

Completion:

2034-09-30

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06085274 | RECRUITING | NA

100 participants

Sentinel lympH Node Biopsy With Indocyanine Green in Breast Cancer After NEoadjuvant Chemotherapy (SHINE)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2025-09-03

Completion:

2026-04-30

Conditions

• Breast Cancer

Interventions

• PROCEDURE

No Results Yet

NCT06084403 | COMPLETED | NA

90 participants

Ultrasound-Guided Adductor Canal Block for Total Knee Arthroplasty Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2023-12-20

Completion:

2024-03-20

Conditions

• Knee Disease
• Knee Deformity
• Knee Pain Chronic
• Knee Arthropathy
• Knee Osteoarthritis

Interventions

• DRUG

No Results Yet

NCT06077773 | TERMINATED | PHASE2

113 participants

Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2023-09-25

Completion:

2024-12-18

Conditions

• Chronic Spontaneous Urticaria

Interventions

• DRUG

Results Available

NCT06074328 | COMPLETED | NA

30 participants

Blended Reality Immersion for Geriatric Head Trauma: The BRIGHT Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2023-11-29

Completion:

2025-08-15

Conditions

• Traumatic Brain Injury

Interventions

• DEVICE

No Results Yet

NCT06070233 | RECRUITING | NA

22 participants

Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2023-10-12

Completion:

2026-12-31

Conditions

• Spasticity as Sequela of Stroke
• Spastic Cerebral Palsy
• Spasticity, Muscle

Interventions

• RADIATION
• OTHER

No Results Yet

NCT06065371 | RECRUITING | PHASE1

20 participants

Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2024-11-20

Completion:

2026-12-31

Conditions

• Gastrointestinal Cancer

Interventions

• DRUG

No Results Yet

NCT06050733 | RECRUITING

16 participants

The Gut Microbiome and Immunotherapy Response in Solid Cancers

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-19

Start Date:

2023-06-30

Completion:

2026-12-30

Conditions

• Cancer

No Results Yet

NCT06034457 | COMPLETED

180 participants

Testing the Effectiveness of WW Clinic GLP1

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-19

Start Date:

2024-01-18

Completion:

2024-10-17

Conditions

• Weight Loss
• Obesity

Results Available

NCT06024265 | COMPLETED | EARLY_PHASE1

10 participants

The Safety and Tolerability Study With ER2001 Intravenous Injection in Adults With Early Manifest Huntington's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2023-04-04

Completion:

2025-01-31

Conditions

• Huntington Disease

Interventions

• DRUG

No Results Yet

NCT06017557 | RECRUITING | NA

151 participants

Predicting Outcome of Cytoreduction in Advanced Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2023-01-02

Completion:

2025-12-15

Conditions

• Ovarian Cancer Stage III
• Ovarian Cancer Stage IV

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06008145 | ACTIVE_NOT_RECRUITING

568 participants

COPD Case Finding In Nottingham and District: C-FIND COPD A Pilot Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-19

Start Date:

2023-09-21

Completion:

2025-12-31

Conditions

• COPD

No Results Yet

NCT05986188 | ACTIVE_NOT_RECRUITING

111 participants

Evaluating a School-based Social and Material Needs Identification System to Prevent Youth Violence Involvement

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-19

Start Date:

2024-02-21

Completion:

2025-10-01

Conditions

• Violence, Physical
• Maltreatment, Child

Interventions

• OTHER

No Results Yet

NCT05973513 | ACTIVE_NOT_RECRUITING

25 participants

Open Trial of Biofeedback for Respiratory Symptoms

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-19

Start Date:

2021-08-01

Completion:

2027-07-31

Conditions

• Shortness of Breath/Dyspnea

No Results Yet

NCT05954494 | COMPLETED

21 participants

Protection Response to Cellular Stress in BPAN's Patient Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-19

Start Date:

2023-10-23

Completion:

2025-10-23

Conditions

• Children and Adults With BPAN Carrying Pathogenic Variants of WDR45

Interventions

• BIOLOGICAL

No Results Yet

NCT05954481 | COMPLETED | NA

47 participants

Stress-Echography in Hereditary Haemorrhagic Telangiectasia Patient With Hepatic Involvement

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2023-08-03

Completion:

2025-01-14

Conditions

• Hereditary Hemorrhagic Telangiectasia
• Rendu Osler Disease

Interventions

• OTHER

No Results Yet

NCT05953363 | COMPLETED

161 participants

Prospective Clinical Evaluation of BD NRFit™ Devices and Accessories.

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-19

Start Date:

2023-07-24

Completion:

2024-05-28

Conditions

• Anesthesia
• Analgesia

Interventions

• DEVICE

Results Available

NCT05947591 | COMPLETED

25 participants

Influence of Gait and Running on Foot Posture

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-19

Start Date:

2023-06-20

Completion:

2023-06-20

Conditions

• Foot Pronation in Healthy Adult

Interventions

• BEHAVIORAL

No Results Yet

NCT05927207 | COMPLETED | NA

40 participants

Pilot Testing of a Mobile Phone App-based Intervention for Parents of Children With Autism Spectrum Disorder (ASD)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-19

Start Date:

2023-08-01

Completion:

2024-08-05

Conditions

• Autism Spectrum Disorder
• Parent-Child Relations

Interventions

• OTHER

No Results Yet

NCT05906888 | COMPLETED

156 participants

Weaning With Tracheostomy - an Observational Study on Patient-centered Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-19

Start Date:

2023-05-08

Completion:

2024-11-30

Conditions

• Weaning Failure
• Mechanical Ventilation
• Patient-centered Care

No Results Yet