Clinical Trials Updated in 2025

NCT05795049 | ACTIVE_NOT_RECRUITING

2000 participants

Genetic Carbohydrate Maldigestion as a Model to Study Food Hypersensitivity

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-19
Start Date:: 2024-07-23
Completion:: 2025-09-30

Conditions

Irritable Bowel Syndrome (IBS)
Sucrase Isomaltase Deficiency

Interventions

OTHER

No Results Yet

NCT05792930 | RECRUITING | NA

60 participants

Developing an Integrated Psychotherapy With Cognitive-behavioral Therapy and Biofeedback Therapy for Somatic Symptom Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-07-11
Completion:: 2026-06-30

Conditions

Somatic Symptom Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05775094 | ACTIVE_NOT_RECRUITING | PHASE1

10 participants

A Study of Romosozumab in Women With Multiple Myeloma and Osteoporosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-03-07
Completion:: 2027-03-31

Conditions

Osteoporosis
Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05767970 | COMPLETED | NA

2315 participants

Stress Toolbox for Healthcare Providers in Mexico

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-04-04
Completion:: 2024-03-31

Conditions

Distress, Emotional
Burnout, Professional
Inflammation
Emotion Regulation

Interventions

BEHAVIORAL

No Results Yet

NCT05764057 | RECRUITING | PHASE3

450 participants

DAPAgliflozine to Attenuate Cardiac RemOdeling afTEr aCuTe myOcardial Infarction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-06-12
Completion:: 2026-10-12

Conditions

AMI
STEMI
NSTEMI
Left Ventricular Dysfunction

Interventions

DRUG

No Results Yet

NCT05761899 | RECRUITING | PHASE1/PHASE2

3 participants

Safety and Efficacy of PMT Therapy of hPAP

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-06-26
Completion:: 2026-09-01

Conditions

Hereditary Pulmonary Alveolar Proteinosis

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05758909 | ACTIVE_NOT_RECRUITING

585 participants

Evaluation of the Viability and Safety of Early Discharge Protocol After TAVI Implantation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-04-04
Completion:: 2026-12-01

Conditions

Aortic Valve Disease
Aortic Valve Stenosis
Heart Valve Diseases

Interventions

DEVICE

No Results Yet

NCT05745493 | COMPLETED | NA

29 participants

Study 1: Social Engage Coaching R61 Phase

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-06-13
Completion:: 2025-09-30

Conditions

Social Isolation
Loneliness
Suicide Ideation
Quality of Life

Interventions

BEHAVIORAL

No Results Yet

NCT05741580 | COMPLETED

70 participants

Peri-urethral Bulk Agent Injection of Bulkamid®

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-10-01
Completion:: 2022-11-30

Conditions

Urinary Incontinence

Interventions

PROCEDURE

No Results Yet

NCT05696392 | TERMINATED | PHASE4

47 participants

The Purpose of This Study is to Evaluate the Effects of Ruxolitinib Cream on Adults With Atopic Dermatitis Experiencing Sleep Disturbance.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-03-16
Completion:: 2025-01-22

Conditions

Atopic Dermatitis

Interventions

DRUG

Results Available

NCT05663203 | RECRUITING | NA

56 participants

A Web-Based Dyadic Intervention for Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-05-01
Completion:: 2026-10-01

Conditions

Colorectal Carcinoma

Interventions

OTHER

No Results Yet

NCT05628948 | RECRUITING

500 participants

Vascular Lab Resource (VLR) Biorepository

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-19
Start Date:: 2019-11-14
Completion:: 2030-12-31

Conditions

Cardiovascular Diseases
Metabolic Disease
Peripheral Artery Disease
Carotid Disease
Aneurysmal Disease
Venous Disease
Thrombosis
Lymphedema
Lipedema
Non-Atherosclerotic Chronic Arterial Occlusive Disease
Vasculitis
Fibromuscular Dysplasia
Arterial Dissection
May-Thurner Syndrome
Thoracic Outlet Syndrome
Vasospasm

No Results Yet

NCT05616273 | COMPLETED

62 participants

Stimulated Glucagon as a Biomarker of Hypoglycemic Risk in Type 1 Diabetes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-05-03
Completion:: 2025-01-28

Conditions

Type 1 Diabetes
Hypoglycemia

Interventions

OTHER

No Results Yet

NCT05582187 | COMPLETED | PHASE1

28 participants

A Clinical Trial of the Study Medicine (Called Fosmanogepix) in Participants With Varying Degrees of Hepatic Function.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-10-31
Completion:: 2025-10-16

Conditions

Hepatic Impairment

Interventions

DRUG

No Results Yet

NCT05575700 | COMPLETED | PHASE4

2904 participants

Safety of Ibuprofen After Major Orthopaedic Surgeries

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-04-17
Completion:: 2025-08-19

Conditions

Pain, Acute
Hip Arthropathy
Knee Arthropathy
Safety Issues
Analgesia
Analgesic Adverse Reaction
Postoperative Pain
Postoperative Complications

Interventions

DRUG

No Results Yet

NCT05572905 | COMPLETED | NA

60 participants

Effect of Acute Bout of Exercise on Levels of PAHSA

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2021-05-01
Completion:: 2025-12-12

Conditions

Insulin Sensitivity

Interventions

OTHER

No Results Yet

NCT05557201 | RECRUITING

700 participants

Cohort of Patients Presenting Unexplained Recurrent Miscarriages and Identification of Early Miscarriage Recidivism Factors

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-10-24
Completion:: 2027-10-31

Conditions

Miscarriage
Early Pregnancy Loss

No Results Yet

NCT05517434 | RECRUITING | PHASE2/PHASE3

148 participants

Autologous BMA vs Saline and LAM + LP-PRP vs Saline Evaluations in Knee OA

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2025-01-01
Completion:: 2026-06-30

Conditions

Osteoarthritis, Knee

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT05499013 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

69 participants

Study to Assess SLN124 in Patients With Polycythemia Vera

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-01-26
Completion:: 2026-09-30

Conditions

Polycythemia Vera

Interventions

DRUG

No Results Yet

NCT05490238 | RECRUITING | NA

708 participants

DIStal Versus COnventional Radial Access for COMPLEX Large-bore Percutaneous Coronary Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-08-31
Completion:: 2026-06-01

Conditions

Vascular Access Site Occlusion

Interventions

PROCEDURE

No Results Yet

NCT05479006 | RECRUITING | NA

30 participants

Determine the Effect of Targeted High-definition Transcranial Direct Current Stimulation (tDCS) on Reducing Post-stroke Upper Limb Motor Impairments

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-09-30
Completion:: 2026-06-30

Conditions

Stroke

Interventions

DEVICE

No Results Yet

NCT05477004 | ENROLLING_BY_INVITATION

100 participants

Observational Study of Ketamine Infusions for the Treatment of Chronic Pain

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-06-01
Completion:: 2026-12-31

Conditions

Chronic Pain

Interventions

DRUG

No Results Yet

NCT05475002 | COMPLETED | NA

92 participants

A Care Empowerment Program Using Virtual Reality for Family Caregivers of People With Dementia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-08-01
Completion:: 2023-07-01

Conditions

Dementia Family Caregiver

Interventions

OTHER

No Results Yet

NCT05465343 | COMPLETED | PHASE2

24 participants

Furmonertinib in EGFR-Mutant NSCLC With Brain Metastases (iFORCE)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-07-11
Completion:: 2025-12-12

Conditions

Furmonertinib
EGFR-mutation
NSCLC
Brain Metastases

Interventions

DRUG

No Results Yet

NCT05429853 | TERMINATED | NA

17 participants

TOLER-ENT Study: A Study to Investigate the Tolerance of the High Energy, High Protein Formula Sondalis® HP 2 kcal

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-07-08
Completion:: 2024-05-28

Conditions

Malnutrition

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05428436 | COMPLETED | PHASE1

24 participants

A Study in Healthy People to Compare 2 Different Formulations of BI 1015550 Taken With or Without Food

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-08-15
Completion:: 2022-09-30

Conditions

Healthy

Interventions

DRUG

Results Available

NCT05407025 | ACTIVE_NOT_RECRUITING

191 participants

Targeting Inflammation for Endometrial Cancer Prevention

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-19
Start Date:: 2021-12-01
Completion:: 2026-12-31

Conditions

Endometrial Carcinoma

Interventions

PROCEDURE
OTHER

No Results Yet

NCT05377476 | COMPLETED | NA

48 participants

Effects of Motor Imagery and Action Observation in People With Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-06-01
Completion:: 2024-04-01

Conditions

Multiple Sclerosis

Interventions

OTHER

No Results Yet

NCT05345158 | RECRUITING | NA

25 participants

R-RPLND as First-line Treatment for Clinical Stage IIA/B Testicular Seminoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-02-23
Completion:: 2030-11-30

Conditions

Lymphadenopathy Retroperitoneal
Stage II Testicular Seminoma

Interventions

PROCEDURE

No Results Yet

NCT05299658 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

An Open-Label Extension for the Phase 2 Study in Early Symptomatic Amyotrophic Lateral Sclerosis Patients on Stable Background Therapy to Assess Bioenergetic Catalysis With CNM-Au8 to Slow Disease Progression in ALS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2021-11-13
Completion:: 2026-06-30

Conditions

Amyotrophic Lateral Sclerosis

Interventions

DRUG

No Results Yet

NCT05287594 | COMPLETED | NA

55 participants

Feasibility of a Train-the-Trainer Delivered Exercise Intervention in Firefighters

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2023-04-01
Completion:: 2025-09-26

Conditions

Firefighter
High Intensity Interval Training

Interventions

BEHAVIORAL

No Results Yet

NCT05276973 | ACTIVE_NOT_RECRUITING | PHASE1

25 participants

Testing the Addition of Ipatasertib to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) for Stage III or IV Epithelial Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-09-08
Completion:: 2025-01-30

Conditions

Fallopian Tube Endometrioid Adenocarcinoma
Fallopian Tube High Grade Serous Adenocarcinoma
Ovarian Endometrioid Adenocarcinoma
Ovarian High Grade Serous Adenocarcinoma
Primary Peritoneal Endometrioid Adenocarcinoma
Primary Peritoneal High Grade Serous Adenocarcinoma
Stage III Fallopian Tube Cancer AJCC v8
Stage III Ovarian Cancer AJCC v8
Stage III Primary Peritoneal Cancer AJCC v8
Stage IV Fallopian Tube Cancer AJCC v8
Stage IV Ovarian Cancer AJCC v8
Stage IV Primary Peritoneal Cancer AJCC v8
Unresectable Fallopian Tube Endometrioid Adenocarcinoma
Unresectable Fallopian Tube High Grade Serous Adenocarcinoma
Unresectable Ovarian Endometrioid Adenocarcinoma
Unresectable Ovarian High Grade Serous Adenocarcinoma
Unresectable Primary Peritoneal Endometrioid Adenocarcinoma
Unresectable Primary Peritoneal High Grade Serous Adenocarcinoma

Interventions

PROCEDURE
DRUG

Results Available

NCT05270213 | RECRUITING | PHASE1

164 participants

Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-07-11
Completion:: 2027-04-30

Conditions

Advanced Cancer

Interventions

DRUG

No Results Yet

NCT05257824 | COMPLETED | PHASE4

528 participants

Optimal Duration of Dual Antiplatelet Therapy After Stent-assisted Coiling

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-06-23
Completion:: 2025-12-02

Conditions

Aneurysm Cerebral
Endovascular Procedures

Interventions

DRUG

No Results Yet

NCT05249101 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

70 participants

A Study of Ivaltinostat Plus Capecitabine or Capecitabine in Metastatic Pancreatic Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-08-15
Completion:: 2026-06-30

Conditions

Metastatic Pancreatic Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT05235425 | COMPLETED | NA

304 participants

The Lifestyle Education About Prediabetes (Leap) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-03-20
Completion:: 2025-11-14

Conditions

PreDiabetes

Interventions

BEHAVIORAL

No Results Yet

NCT05208710 | RECRUITING | EARLY_PHASE1

45 participants

PANHPVAX, Study of a New HPV Vaccine in Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-11-07
Completion:: 2027-12-31

Conditions

HPV

Interventions

BIOLOGICAL

No Results Yet

NCT05201469 | RECRUITING | PHASE2

74 participants

VIBRANT: VIB4920 for Active Lupus Nephritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-05-16
Completion:: 2026-08-31

Conditions

Lupus Nephritis

Interventions

DRUG

No Results Yet

NCT05153395 | SUSPENDED | EARLY_PHASE1

65 participants

Impact of Intranasal Insulin on Sympathetic Activity and Cerebral Vasodilation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2021-12-01
Completion:: 2027-06-30

Conditions

Healthy
Vasodilation
Insulin Resistance
Autonomic Dysfunction
Obesity

Interventions

OTHER
DRUG

No Results Yet

NCT05115630 | COMPLETED | PHASE2

24 participants

Off-the-shelf NK Cells + SCT for Myeloid Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-19
Start Date:: 2022-04-08
Completion:: 2025-05-15

Conditions

Myeloid Malignancies
Acute Myeloid Leukemia
Myelodysplastic Syndrome
Chronic Myeloid Leukemia

Interventions

DRUG

Results Available