Clinical Trials Updated in 2025

NCT07029009 | RECRUITING | PHASE2

50 participants

Liraglutide Treatment in Patients With Maturity-onset Diabetes of the Young (MODY)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-05-08
Completion:: 2026-08-31

Conditions

Maturity Onset Diabetes of the Young

Interventions

DRUG

No Results Yet

NCT07026591 | RECRUITING

40 participants

Epilepsy and Driving

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-11-06
Completion:: 2027-11-30

Conditions

Epilepsy

No Results Yet

NCT07016698 | RECRUITING | NA

600 participants

Real-World Registry of the Rotarex(TM) Rotational Excisional Atherectomy System (XTRACT Registry)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-09-29
Completion:: 2029-03-31

Conditions

Peripheral Arterial Disease(PAD)

Interventions

DEVICE

No Results Yet

NCT07014618 | RECRUITING

420 participants

Navigator-Assisted Hypofractionation (NAVAH) on Radiation Therapy Completion in Breast Cancer and Prostate Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-10-16
Completion:: 2029-10-31

Conditions

Breast Cancer
Prostate Cancer

Interventions

OTHER

No Results Yet

NCT07008300 | WITHDRAWN | EARLY_PHASE1

0 participants

Safety, Tolerability, and Pharmacokinetics of an Oral Withania Somnifera Product in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-07-01
Completion:: 2025-12-01

Conditions

Healthy
Aging

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07000552 | COMPLETED | NA

68 participants

Emotional Freedom Technique During Pregnancy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-01-15
Completion:: 2025-10-15

Conditions

Fear of Birth
Birth Memory
Postpartum Sense of Security

Interventions

OTHER

No Results Yet

NCT06987695 | ACTIVE_NOT_RECRUITING | PHASE3

279 participants

Efficacy and Safety of Maridebart Cafraglutide in Adult Participants in Japan Who Have Obesity Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-06-13
Completion:: 2027-04-27

Conditions

Obesity Disease

Interventions

DRUG

No Results Yet

NCT06968143 | RECRUITING | NA

150 participants

Investigating Patient Satisfaction With Smart Knee Implants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-09-01
Completion:: 2027-04-30

Conditions

Total Knee Arthroplasty
Knee Replacement
Knee Replacement Arthroplasty
Knee Osteoarthritis

Interventions

DEVICE

No Results Yet

NCT06955013 | RECRUITING

118 participants

Ultrasound to View Abdominal Wall Muscle Layers

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-08-25
Completion:: 2027-12-31

Conditions

Healthy Volunteers

No Results Yet

NCT06947135 | RECRUITING | NA

166 participants

Stellate Ganglion Morphine Infiltration on Myocardial Ischemia-Reperfusion Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-05-29
Completion:: 2026-06-04

Conditions

Acute Myocardial Infarction

Interventions

DRUG

No Results Yet

NCT06931886 | ENROLLING_BY_INVITATION | NA

4 participants

Pulmonary Hypertension Inspiratory Training

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-10-25
Completion:: 2026-05-31

Conditions

Pulmonary Hypertension

Interventions

OTHER

No Results Yet

NCT06931197 | NOT_YET_RECRUITING | NA

20 participants

Why Wait? Initiating Contingency Management in Traumatically Injured Patients During Hospitalization

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2026-01-01
Completion:: 2026-07-31

Conditions

Contingency Management
Methamphetamine Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06928311 | COMPLETED | NA

25 participants

This Study Explores Whether Adding Natural Elements Like Plants and Sunlight to Indoor Gyms Makes Exercise Feel Easier, More Enjoyable, and Improves Performance. By Comparing Workouts in Nature-inspired and Plain Gym Settings, it Aims to Find Better Ways to Design Fitness Spaces in Cities.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-04-04
Completion:: 2025-10-16

Conditions

Biophilic Environmental Design
Traditional Exercise Design

Interventions

OTHER

No Results Yet

NCT06926634 | RECRUITING | PHASE2

32 participants

Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (HG-NENs)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-12-09
Completion:: 2034-12-31

Conditions

High Grade Neuroendocrine Neoplasms

Interventions

DRUG

No Results Yet

NCT06912009 | RECRUITING

100 participants

Duration of Therapeutic Anticoagulation in Patients With Pulmonary Embolism

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-11-06
Completion:: 2025-12-31

Conditions

Pulmonary Embolism

No Results Yet

NCT06911658 | RECRUITING

350 participants

Infectious Complications After Esophagectomy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-08-27
Completion:: 2026-07-28

Conditions

Esophagectomy
Postoperative Complications
Infections
Pneumonia

No Results Yet

NCT06908993 | RECRUITING | PHASE3

133 participants

Tepotinib vs Standard Treatment in Patients With Advanced MET Exon 14 Mutated Non-Small Cell Lung Cancer Previously Treated

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-12-09
Completion:: 2028-03-15

Conditions

Advanced Non Small Cell Lung Cancer
MET Exon 14 Mutation

Interventions

DRUG

No Results Yet

NCT06903286 | TERMINATED | PHASE2

16 participants

Extension Study of Participants From SPG302-ALS-001

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-05-29
Completion:: 2025-06-30

Conditions

Amyotrophic Lateral Sclerosis (ALS)

Interventions

DRUG

No Results Yet

NCT06898749 | NOT_YET_RECRUITING | NA

76 participants

Impact of Canine Mediation Practice in Psychomotor Therapy on Improving the Quality of Life in Adult Epileptic Patients.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2026-01-31
Completion:: 2029-06-30

Conditions

Epilepsy

Interventions

OTHER

No Results Yet

NCT06896708 | RECRUITING | NA

766 participants

Effect of Intensive Lipid-Lowering Therapy on Coronary Atherosclerotic Plaque Progression in Young and Middle-Aged Patients With Chronic Coronary Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-08-12
Completion:: 2027-07-01

Conditions

Chronic Coronary Syndrome

Interventions

DRUG

No Results Yet

NCT06891352 | RECRUITING | NA

180 participants

Optimization of Chrononutrition to Reduce the Risk of Disease in Shift Workers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-06-02
Completion:: 2028-08-31

Conditions

Night Shift Work
Time Restricted Eating
Overweight
Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT06891131 | RECRUITING

10 participants

Implementation of an Empiric Transfusion Bundle for Out of Hospital Patients With Haemorrhagic Shock

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-06-01
Completion:: 2027-04-01

Conditions

Haemorrhagic Shock
Trauma Coagulopathy

No Results Yet

NCT06883097 | RECRUITING | NA

314 participants

Quitting Matters Human Immunodeficiency Virus Hybrid Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-08-18
Completion:: 2028-12-31

Conditions

Tobacco
Tobacco Abstinence
Smoking Cessation
Smoking Cessation; Tobacco Dependence
Human Immunodeficiency Virus (HIV)
Tobacco Dependence Caused by Cigarettes
Cancer Prevention

Interventions

BEHAVIORAL

No Results Yet

NCT06869850 | RECRUITING | NA

1600 participants

Milk Fat Globule Membrane-Enhanced RUTF for Children With Severe Acute Malnutrition

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-09-22
Completion:: 2027-12-01

Conditions

Severe Acute Malnutrition
Cognitive Impairment
Kwashiorkor
Severe Wasting

Interventions

DIETARY_SUPPLEMENT
DRUG

No Results Yet

NCT06863779 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:: 2025-12-17

No Results Yet

NCT06859710 | RECRUITING | PHASE1

30 participants

THC and CBD: A Controlled Human Study Probing a Harm Reduction Strategy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-11-05
Completion:: 2027-09-01

Conditions

Abuse, Drug
Pain

Interventions

DRUG

No Results Yet

NCT06855069 | RECRUITING | PHASE3

468 participants

HS-20089 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-03-13
Completion:: 2027-03-07

Conditions

Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT06846112 | ACTIVE_NOT_RECRUITING | NA

248 participants

Randomized Clinical Trial Aimed at Comparing Unclamped Robotic Partial Nephrectomy With or Without Renorrhaphy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-07-07
Completion:: 2028-07-07

Conditions

Kidney Cancer

Interventions

PROCEDURE

No Results Yet

NCT06845358 | WITHDRAWN | PHASE1

0 participants

Safety and Challenge Study of BCG TICE(R) Vaccination to Test Tuberculosis Immunity in Heathy Humans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-11-26
Completion:: 2026-09-01

Conditions

Tuberculosis

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT06817330 | RECRUITING | NA

92 participants

The Effect of a Music Intervention on Postictal Agitation in Electroconvulsive Therapy Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-11-25
Completion:: 2027-02-28

Conditions

Music Intervention
Electroconvulsive Therapy Treated Patients
Agitation on Recovery From Sedation

Interventions

OTHER

No Results Yet

NCT06807450 | COMPLETED | NA

36 participants

Repair of Oronasal Fistula Using Interpositional Buccal Pad of Fat as a Free Graft in a Cleft Palate Patient

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-10-11
Completion:: 2025-03-30

Conditions

Cleft Palate

Interventions

PROCEDURE

No Results Yet

NCT06801535 | RECRUITING | NA

10 participants

Efficacy of 3D-Printed Mouth Splints

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-02-21
Completion:: 2026-12-31

Conditions

Microstomia

Interventions

DEVICE

No Results Yet

NCT06791902 | RECRUITING | NA

10 participants

Study on Preliminary Safety and Efficacy of Adaptive DBS Aligned to Locomotor States to Improve Locomotor Functions in Parkinson's Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-01-01
Completion:: 2027-01-01

Conditions

Parkinson Disease

Interventions

DEVICE

No Results Yet

NCT06773949 | RECRUITING | NA

20 participants

Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-12-15
Completion:: 2027-01-31

Conditions

Major Depressive Disorder (MDD)
Treatment Resistant Depression (TRD)

Interventions

DEVICE

No Results Yet

NCT06756269 | RECRUITING | PHASE2

330 participants

To Evaluate the Safety and Immunogenicity of 15-valent HPV Recombinant Vaccine in Chinese People Aged 9-45 Years

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-01-15
Completion:: 2025-10-30

Conditions

HPV Infection
HPV-Related Carcinoma
HPV-Related Intraepithelial Neoplasia
Genital Wart

Interventions

BIOLOGICAL

No Results Yet

NCT06751810 | COMPLETED | NA

30 participants

Nutritional Status in Children With Food Allergy: Evaluation of a New Supplement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-12-30
Completion:: 2025-09-30

Conditions

Food Allergies

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT06742957 | COMPLETED | PHASE3

560 participants

Study Comparing Tapinarof Cream 1% To VTAMA ® (Tapinarof Cream 1%) In the Treatment of Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-12-17
Completion:: 2025-10-07

Conditions

Plaque Type Psorisis

Interventions

DRUG

No Results Yet

NCT06730009 | RECRUITING | PHASE1/PHASE2

42 participants

Phase I/II Study: Allogeneic NK-cell Therapy With Chemotherapy for Post-Surgery PDA or Cholangiocarcinoma Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-10-21
Completion:: 2029-01-31

Conditions

Pancreatic Carcinoma Stage II
Cholangiocarcinoma Resectable

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06729411 | COMPLETED | NA

40 participants

Minimal Offloading Dressing for the Treatment of Plantar Diabetes-related Foot Ulcers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-12-01
Completion:: 2024-09-01

Conditions

Diabetic Foot Ulcer
Offloading

Interventions

DEVICE

No Results Yet

NCT06724016 | RECRUITING | PHASE1

292 participants

Dose Escalation and Expansion Study of HM16390 Alone or With Pembrolizumab in Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-12-11
Completion:: 2031-07-31

Conditions

Advanced or Metastatic Solid Tumors

Interventions

DRUG

No Results Yet