Clinical Trials Updated in 2025

NCT05944965 | COMPLETED | PHASE1/PHASE2

27 participants

Pharyngeal Muscle Control Mechanisms of Atomoxetine-plus-oxybutynin in Obstructive Sleep Apnea

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-12-01
Completion:: 2025-06-17

Conditions

OSA

Interventions

DRUG

No Results Yet

NCT05944692 | RECRUITING

90 participants

Epilepsy Seizure Detection With Innovative Tripolar EEG (tEEG)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-09-01
Completion:: 2026-08-03

Conditions

Epilepsy

Interventions

DEVICE

No Results Yet

NCT05932134 | COMPLETED | NA

100 participants

High Protein, Core Muscle Rehab, Muscular Electrostimulation in Prolonged Mechanical Ventilation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-09-18
Completion:: 2025-03-21

Conditions

Prolonged Mechanical Ventilation
Protein Deficiency

Interventions

DIETARY_SUPPLEMENT
BEHAVIORAL
DEVICE

Results Available

NCT05930405 | COMPLETED | NA

252 participants

Effect of the PIEB Versus CEI on the Quality of Postoperative Recovery in Patients Undergoing VATS Lobectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-10-20
Completion:: 2024-10-30

Conditions

Video-assisted Thoracic Surgery

Interventions

PROCEDURE

No Results Yet

NCT05926804 | RECRUITING | NA

500 participants

A "Screen and Treat" Helicobacter Pylori Eradication Trial in Adolescents in Three Regions of Chile

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2022-08-02
Completion:: 2026-10-31

Conditions

Helicobacter Pylori Infection

Interventions

DRUG

No Results Yet

NCT05919823 | COMPLETED | PHASE3

202 participants

A Study to Assess the Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Chinese Adult Subjects With DSM-5 Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-05-29
Completion:: 2024-09-16

Conditions

Schizophrenia

Interventions

DRUG

Results Available

NCT05916469 | RECRUITING

300 participants

Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-09-24
Completion:: 2028-12-31

Conditions

Heavy Menstrual Bleeding
Bleeding Disorder
Von Willebrand Diseases

Interventions

DRUG

No Results Yet

NCT05913622 | RECRUITING | NA

430 participants

A Study on the Effects of Left Ventricular Unloading in the Setting of VA ECMO Support

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-06-08
Completion:: 2027-07-01

Conditions

Cardiogenic Shock

Interventions

DEVICE

No Results Yet

NCT05908539 | COMPLETED | NA

1057 participants

A Multi-level and Mixed-method Impact Evaluation for the Jockey Club Elders Get Active Fitness Campaign

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-01-02
Completion:: 2024-06-30

Conditions

Aging Well

Interventions

BEHAVIORAL

No Results Yet

NCT05891587 | COMPLETED | PHASE2

80 participants

Semaglutide Therapy for Alcohol Reduction - Tulsa

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-07-07
Completion:: 2025-07-30

Conditions

Alcohol Use Disorder

Interventions

DRUG

No Results Yet

NCT05880004 | RECRUITING | NA

537 participants

Developing a Support Application for Food Pantries (SAFPAS) to Improve Client Access to Healthy Foods & Enhance Emergency Preparedness

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-06-14
Completion:: 2026-11-30

Conditions

Improving Healthy Food Access in Food Insecurity Populations in Normal and Emergency Situations

Interventions

BEHAVIORAL

No Results Yet

NCT05879822 | ACTIVE_NOT_RECRUITING | PHASE2

73 participants

A Study to Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-10-30
Completion:: 2026-07-22

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT05871151 | COMPLETED | NA

25 participants

Combining VNS With PT Interventions for Individuals With PD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-10-01
Completion:: 2024-05-25

Conditions

Parkinson Disease

Interventions

DEVICE
BEHAVIORAL

Results Available

NCT05865561 | RECRUITING

100 participants

Identification of Volatile Organic Compounds (VOCs) as Biopredictors of Epileptic Seizures

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-02-03
Completion:: 2026-06-24

Conditions

Epilepsy

Interventions

OTHER

No Results Yet

NCT05863702 | COMPLETED | NA

53 participants

Staying Healthy With Follow-up Care: A Mobile Chatbot Feasibility Study for AYA Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-09-11
Completion:: 2025-09-01

Conditions

Survivorship

Interventions

BEHAVIORAL

No Results Yet

NCT05856981 | RECRUITING | PHASE1

130 participants

Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-04-03
Completion:: 2027-05-31

Conditions

Solid Tumor, Adult
Metastatic Solid Tumor
Refractory Cancer
CRC, Colorectal Cancer
RCC, Clear Cell Adenocarcinoma
NSCLC (Advanced Non-small Cell Lung Cancer)
Endometrial Cancer

Interventions

DRUG

No Results Yet

NCT05847621 | COMPLETED | NA

144 participants

Linking Individuals Needing Care for Substance Use Disorders to Peer Coaches

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2024-08-16
Completion:: 2025-09-30

Conditions

Substance Use Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT05846932 | COMPLETED | NA

73 participants

Preliminary Efficacy of Occupational Therapy Integrating Horses on Self-regulation in Youth With Autism

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-03-21
Completion:: 2025-04-23

Conditions

Autism Spectrum Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05846594 | COMPLETED | NA

463 participants

A Study to Evaluate the Impact of Liquid Biopsy in Participants With a Clinical Diagnosis of Advanced Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-09-14
Completion:: 2024-09-06

Conditions

Metastatic Lung Cancer
Metastatic Gastrointestinal Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05843175 | COMPLETED | NA

20 participants

Maternal ExeRcIse Timing to Optimise Postprandial Glucose in Type 1 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-06-22
Completion:: 2025-09-30

Conditions

Pregnancy in Diabetic
Type 1 Diabetes

Interventions

OTHER

No Results Yet

NCT05832151 | COMPLETED | PHASE2

382 participants

A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adults With Diabetic Gastroparesis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-03-27
Completion:: 2025-11-14

Conditions

Diabetic Gastroparesis

Interventions

DRUG

No Results Yet

NCT05818189 | RECRUITING | NA

60 participants

Cortical Correlates of Gait in Parkinson's Disease: Impact of Medication and Cueing

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-01-15
Completion:: 2027-10-01

Conditions

Parkinson Disease

Interventions

DEVICE

No Results Yet

NCT05805384 | RECRUITING | NA

60 participants

Evaluating a Noise Reduction Algorithm With Cochlear Implant Users

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-03-01
Completion:: 2027-03-01

Conditions

Hearing Impairment

Interventions

DEVICE

No Results Yet

NCT05794087 | RECRUITING | NA

120 participants

The Role of Macrophage Activation in Lung Injury Following Ozone Exposure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-02-07
Completion:: 2027-06-01

Conditions

Air Pollution

Interventions

OTHER

No Results Yet

NCT05780788 | COMPLETED | NA

36 participants

Characterizing Orthodontic Tooth Movement With Photographic Scans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2020-12-31
Completion:: 2024-03-20

Conditions

Canine Retraction

Interventions

DEVICE

Results Available

NCT05774392 | WITHDRAWN

0 participants

An Observational Study of Patients With Chronic Kidney Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-04-30
Completion:: 2025-04-07

Conditions

Kidney Disease, Chronic
End Stage Kidney Disease

Interventions

OTHER

No Results Yet

NCT05766501 | ACTIVE_NOT_RECRUITING | PHASE3

641 participants

A Study of Doravirine/Islatravir (DOR/ISL, MK-8591A) for the Treatment of Human Immunodeficiency Virus 1 (HIV-1) Infection in Participants Who Previously Received DOR/ISL (MK-8591A-054)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-03-17
Completion:: 2025-10-16

Conditions

HIV Infection

Interventions

DRUG

No Results Yet

NCT05734105 | ACTIVE_NOT_RECRUITING | PHASE3

54 participants

A Study of Ripretinib vs Sunitinib in Patients With Advanced GIST With Specific KIT Exon Mutations Who Were Previously Treated With Imatinib

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-12-13
Completion:: 2027-12-31

Conditions

GIST

Interventions

DRUG

No Results Yet

NCT05731271 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

111 participants

A First-in-Human, Phase 1 Study of TST003 in Subjects With Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-02-08
Completion:: 2026-06-30

Conditions

Locally Advanced Solid Tumor
Metastatic Tumor
Colorectal Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT05725668 | RECRUITING | NA

336 participants

A Study of Dual-task Exercise Training to Prevent Falls Among Older Adults With Mild Cognitive Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-07-15
Completion:: 2027-07-30

Conditions

Mild Cognitive Impairment
Accidental Falls
Aging

Interventions

BEHAVIORAL

No Results Yet

NCT05721053 | ACTIVE_NOT_RECRUITING

150 participants

Improving Outcomes for Older Adults Undergoing Radiation Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2022-11-09
Completion:: 2025-10-31

Conditions

Cancer
Radiation Therapy

No Results Yet

NCT05708716 | RECRUITING | NA

80 participants

Diet and Cognitive Training in Hematologic Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2022-11-22
Completion:: 2026-12-31

Conditions

Cognitive Impairment
Hematologic Malignancy

Interventions

BEHAVIORAL

No Results Yet

NCT05670288 | RECRUITING

35 participants

Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-10-15
Completion:: 2026-12-01

Conditions

Spinal Cord Injuries
Gut Microbiome

No Results Yet

NCT05669027 | RECRUITING | NA

150 participants

Mobile Neurofeedback for Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-10-02
Completion:: 2027-05-01

Conditions

Chronic Low Back Pain

Interventions

DEVICE

No Results Yet

NCT05668949 | WITHDRAWN | PHASE1/PHASE2

0 participants

Phase I/II Open Label Study Evaluating the Safety and Efficacy of Combining STAT3 Inhibition (TTI-101) With Anti-PD-1 Therapy (Pembrolizumab) in Patients With Recurrent or Metastatic (RM) Head and Neck Squamous Cell Carcinoma (HNSCC)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2025-09-23
Completion:: 2025-09-23

Conditions

Head and Neck Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT05655520 | TERMINATED | PHASE3

153 participants

A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Huntington's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2022-12-14
Completion:: 2025-01-20

Conditions

Huntington's Disease

Interventions

DRUG

Results Available

NCT05637762 | COMPLETED

13 participants

Development of a Seizure Detection Algorithm Based on Heart Rate and Movement Analysis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-06-05
Completion:: 2025-04-24

Conditions

Epilepsy

Interventions

OTHER

No Results Yet

NCT05635409 | ACTIVE_NOT_RECRUITING | PHASE1

8 participants

A Trial to Determine the Safety and Tolerability of Transplanted Stem Cell Derived Dopamine Neurons to the Brains of Individuals With Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2022-11-30
Completion:: 2027-01-31

Conditions

Parkinson Disease

Interventions

BIOLOGICAL

No Results Yet

NCT05635019 | COMPLETED | NA

105 participants

FoodRx for Obesity Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2022-12-01
Completion:: 2024-07-01

Conditions

Obesity
Food Insecurity

Interventions

BEHAVIORAL

Results Available

NCT05632627 | COMPLETED | PHASE2

43 participants

Cannabinoids and Traumatic Brain Injury: A Randomized, Placebo Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-17
Start Date:: 2023-04-11
Completion:: 2025-07-07

Conditions

Brain Injuries, Traumatic

Interventions

DRUG

No Results Yet