Clinical Trials Updated in 2025

NCT05032261 | COMPLETED

100 participants

ICU Norepinephrine Load

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-09-01
Completion:: 2024-12-31

Conditions

Circulatory Collapse and Shock

Interventions

DRUG

No Results Yet

NCT05001347 | COMPLETED | PHASE2

25 participants

A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-11-02
Completion:: 2023-02-08

Conditions

Ovarian Cancer
Head and Neck Cancer
Non Small Cell Lung Cancer
Gastrointestinal Cancer
Triple Negative Breast Cancer
Ovarian Carcinoma

Interventions

DRUG

Results Available

NCT05000866 | ACTIVE_NOT_RECRUITING | NA

484 participants

Expanding the Potential of Couples HIV Testing: Adjunct Modules to Reduce Drug Use Among Vulnerable Male Couples

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-10-13
Completion:: 2026-05-31

Conditions

Substance Use
HIV Infections

Interventions

BEHAVIORAL

No Results Yet

NCT04987489 | COMPLETED | PHASE2

53 participants

A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2022-03-28
Completion:: 2025-09-03

Conditions

Sickle Cell Disease
Thalassemia

Interventions

DRUG

No Results Yet

NCT04985695 | RECRUITING | NA

110 participants

Influence of Analgesic Technique on Post Operative Rehabilitation After Median Laparotomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-10-11
Completion:: 2028-10-10

Conditions

Laparotomy

Interventions

DRUG
PROCEDURE

No Results Yet

NCT04973137 | TERMINATED | PHASE3

208 participants

A Study to Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients With AL Amyloidosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-08-30
Completion:: 2025-04-02

Conditions

Light Chain (AL) Amyloidosis

Interventions

DRUG
OTHER

Results Available

NCT04948866 | COMPLETED | NA

884 participants

Palliative Care for Persons With Late-stage Alzheimer's and Related Dementias and Their Caregivers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-07-26
Completion:: 2025-02-01

Conditions

Dementia
Dementia, Vascular
Dementia With Lewy Bodies
Dementia Frontal
Dementia, Mixed
Dementia Alzheimers
Alzheimer Disease
Dementia Severe

Interventions

BEHAVIORAL

Results Available

NCT04858009 | RECRUITING | PHASE2

40 participants

Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2024-02-15
Completion:: 2029-07-31

Conditions

Metastatic Pancreatic Carcinoma
Stage IV Pancreatic Cancer AJCC v8
Metastatic Malignant Neoplasm in the Peritoneum

Interventions

DRUG
PROCEDURE

No Results Yet

NCT04799860 | COMPLETED | NA

12000 participants

Act in Time -Implementation of Health Promotive Work-way in Primary Care Setting (AcTi)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-03-30
Completion:: 2024-12-31

Conditions

Health Knowledge, Attitudes, Practice

Interventions

BEHAVIORAL

No Results Yet

NCT04779216 | COMPLETED | PHASE3

30 participants

Effects of Romosozumab on Bone Density in Women With Anorexia Nervosa

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-09-20
Completion:: 2024-10-24

Conditions

Bone Density, Low
Bone Loss
Anorexia Nervosa
Eating Disorders

Interventions

DRUG

Results Available

NCT04765709 | TERMINATED | PHASE2

10 participants

Durvalumab and Chemotherapy Induction Followed by Durvalumab and Radiotherapy in Large Volume Stage III NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-09-24
Completion:: 2025-01-30

Conditions

Non-small Cell Lung Cancer Stage III

Interventions

COMBINATION_PRODUCT
BIOLOGICAL

No Results Yet

NCT04763317 | RECRUITING

3000 participants

Precision Medicine in the Prostate Cancer Care Pathway

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2019-02-14
Completion:: 2029-12-31

Conditions

Prostate Cancer
Genetic Predisposition

Interventions

GENETIC

No Results Yet

NCT04722341 | RECRUITING | NA

175 participants

Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and Moderators

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2022-01-01
Completion:: 2026-06-30

Conditions

Colorectal Cancer
Breast Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT04707937 | COMPLETED | NA

150 participants

Evaluation of a Brachytherapy Discharge Education Program to Improve Patient Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-08-19
Completion:: 2025-12-05

Conditions

Gynecologic Cancer

Interventions

OTHER

No Results Yet

NCT04702802 | COMPLETED | NA

36 participants

Study to Evaluate the Safety of the Viscoelastic Substance PRO-149, Compared to Healon® EndoCoat.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-09-07
Completion:: 2021-10-29

Conditions

Age-related Cataract
Phacoemulsification

Interventions

DEVICE

Results Available

NCT04692597 | TERMINATED | NA

83 participants

Low Level Laser Therapy (LLLT) for the Treatment of Hand Osteoarthritis.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-03-02
Completion:: 2025-12-09

Conditions

Low Level Laser Therapy
Osteoarthritis
Family Medicine
Pain Management
Integrative Medicine

Interventions

DEVICE

No Results Yet

NCT04683848 | COMPLETED | PHASE2

72 participants

Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-08-27
Completion:: 2024-12-24

Conditions

Spinal Cord Injury

Interventions

BIOLOGICAL

No Results Yet

NCT04634812 | COMPLETED | PHASE1

7 participants

Mass Balance Study of KBP-5074 in Healthy Male Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-12-03
Completion:: 2020-12-23

Conditions

Healthy

Interventions

DRUG

No Results Yet

NCT04606537 | COMPLETED | PHASE1

24 participants

Drug to Drug Interaction Study of KBP-5074 in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-10-24
Completion:: 2020-11-30

Conditions

Healthy
Drug Drug Interaction

Interventions

DRUG

No Results Yet

NCT04594369 | COMPLETED | PHASE3

1767 participants

A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-12-01
Completion:: 2024-10-28

Conditions

Non-Cystic Fibrosis Bronchiectasis

Interventions

DRUG

Results Available

NCT04577911 | RECRUITING

248 participants

How is Social Connection Represented in the Brain?

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-04-01
Completion:: 2026-11-30

Conditions

Loneliness

Interventions

OTHER

No Results Yet

NCT04575740 | COMPLETED | NA

209 participants

Phenotyping Mechanistic Pathways for Adverse Health Outcomes in Sleep Apnea

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-09-10
Completion:: 2025-06-30

Conditions

Sleep Apnea

Interventions

DEVICE

No Results Yet

NCT04565925 | RECRUITING | PHASE2

24 participants

Sildenafil for Treatment of Urinary Incontinence in Patients With Spinal Cord Injuries

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-07-07
Completion:: 2026-12-01

Conditions

Spinal Cord Injuries
Urinary Incontinence

Interventions

DRUG

No Results Yet

NCT04534699 | COMPLETED | PHASE1

12 participants

Pharmacokinetics of KBP-5074 in Patients With Moderate Hepatic Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-08-27
Completion:: 2020-11-19

Conditions

Moderate Hepatic Impairment
Healthy

Interventions

DRUG

No Results Yet

NCT04491045 | COMPLETED | NA

1382 participants

Implementation Strategies for Task-Shifting Depression Care Depression Care in Vietnam

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-12-01
Completion:: 2025-04-30

Conditions

Depression

Interventions

OTHER

No Results Yet

NCT04445064 | TERMINATED | PHASE2

17 participants

Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-08-14
Completion:: 2024-06-08

Conditions

Oropharynx Squamous Cell Carcinoma
Larynx Squamous Cell Carcinoma
Hypopharynx Squamous Cell Carcinoma
Oral Cavity Squamous Cell Carcinoma

Interventions

BIOLOGICAL

No Results Yet

NCT04308928 | COMPLETED

332 participants

Evaluation of New Biomarker-based Approaches for Improving the Diagnosis of Childhood Tuberculous Meningitis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-04-01
Completion:: 2024-10-31

Conditions

Tuberculous Meningitis

No Results Yet

NCT04261686 | COMPLETED | NA

100 participants

Post Approval Study of the BARD® COVERA™ Arteriovenous (AV) Stent Graft

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-07-03
Completion:: 2025-09-16

Conditions

Arteriovenous Fistula

Interventions

DEVICE

No Results Yet

NCT04247620 | COMPLETED | PHASE2

144 participants

DiaBetter Together for Young Adults With Type 1 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-12-15
Completion:: 2024-09-30

Conditions

Type 1 Diabetes

Interventions

BEHAVIORAL

Results Available

NCT04236908 | COMPLETED | NA

276 participants

Accessible Acupuncture for the Warrior With Acute Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-08-25
Completion:: 2025-12-09

Conditions

Acupuncture
Low Back Pain

Interventions

DRUG
DEVICE

No Results Yet

NCT04234139 | ENROLLING_BY_INVITATION

300 participants

Cohort/Ethics Study of Patients With Severe Alcoholic Hepatitis Undergoing Early Liver Transplantation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-04-01
Completion:: 2028-12-31

Conditions

Liver Diseases, Alcoholic
Alcohol-Related Disorders
Transplant; Failure, Liver
Transplant; Complication, Rejection
Liver Diseases
Hepatitis, Alcoholic
Alcohol-Induced Disorders

Interventions

PROCEDURE

No Results Yet

NCT04214119 | RECRUITING

2500 participants

EsophaCap for the Detection of Early Esophageal Carcinoma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2016-01-12
Completion:: 2028-12-19

Conditions

Barrett Esophagus
Esophageal Cancer
Gastric Cancer

No Results Yet

NCT04193410 | COMPLETED

315 participants

Healthy Childcare Centre of the Future

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-06-15
Completion:: 2023-06-28

Conditions

Health and Wellbeing of Primary School-aged Children

Interventions

BEHAVIORAL

Results Available

NCT04191551 | RECRUITING

600 participants

The GAstric Precancerous Conditions Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-16
Start Date:: 2018-07-30
Completion:: 2028-06-30

Conditions

Gastric Cancer
Intestinal Metaplasia of Gastric Mucosa
Helicobacter Pylori Infection
Atrophic Gastritis

No Results Yet

NCT04190680 | COMPLETED | NA

226 participants

Kokkerelli Learning Street Effect Evaluation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2020-03-15
Completion:: 2022-08-31

Conditions

Fruit and Vegetable Consumption in Children

Interventions

BEHAVIORAL

Results Available

NCT04166643 | COMPLETED | NA

159 participants

Worksite Wellness Within Long-term Care Facilities

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2022-06-28
Completion:: 2024-10-31

Conditions

Worksite Health Promotion
Lifestyle Risk Reduction
Cardiovascular Diseases
Occupational Stress
Healthcare Workers

Interventions

BEHAVIORAL

No Results Yet

NCT04164641 | RECRUITING | NA

69 participants

Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic Gait Correction in Reducing Diabetic Foot Ulceration Or Subsequent Amputation in Patients With a History of a Diabetic Foot Ulceration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2019-12-09
Completion:: 2026-12-31

Conditions

Diabetic Foot Ulcer

Interventions

DEVICE

No Results Yet

NCT04110665 | COMPLETED | PHASE4

92 participants

Multimodal Analgesia Strategies After Major Shoulder Ambulatory Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2017-09-01
Completion:: 2019-09-26

Conditions

Tendon Injuries

Interventions

DRUG

No Results Yet

NCT04104438 | COMPLETED | PHASE4

71 participants

Examination of Immunosuppression Adjustment Impact on Kidney Function in Liver Transplant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2021-01-15
Completion:: 2024-09-30

Conditions

Asses Immunosuppression Modulation on Renal Recovery Post LT

Interventions

DRUG

Results Available

NCT04057638 | RECRUITING | NA

10 participants

Craniomaxillofacial and Upper Extremity Allotransplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-16
Start Date:: 2019-06-17
Completion:: 2026-01-01

Conditions

Face Injuries
Hand Injuries
Craniofacial Injuries
Upper Extremity Injuries
Facial Injuries
Facial Deformity

Interventions

PROCEDURE

No Results Yet