Clinical Trials Updated in 2025

NCT07178015 | ENROLLING_BY_INVITATION

855 participants

A Cohort Study on Cardiovascular and Cerebrovascular Outcomes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2021-12-30
Completion:: 2025-12-30

Conditions

Stroke
Atheroscleroses

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT07176663 | NOT_YET_RECRUITING | NA

15 participants

Efficacy and Safety of Tirzepatide (Spartina) in Chronic Kidney Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2026-02-01
Completion:: 2026-04-01

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT07169214 | RECRUITING | PHASE1

39 participants

Evaluation of Safety, Efficacy, and Pharmacokinetics of BT-114143 Injection in Patients With Abnormal Uterine Bleeding

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2024-10-30
Completion:: 2025-09-23

Conditions

Abnormal Uterine Bleeding

Interventions

DRUG

No Results Yet

NCT07167836 | ENROLLING_BY_INVITATION | NA

1000 participants

Automated Clinical Pathway for Inflammatory Bowel Disease Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-12-12
Completion:: 2026-12-13

Conditions

Inflammatory Bowel Disease
Inflammatory Bowel Disease (IBD)

Interventions

OTHER

No Results Yet

NCT07153068 | RECRUITING | PHASE1/PHASE2

12 participants

SupCD7 CART for Relapsed or Refractory CD7 Positive Hematologic Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-06-28
Completion:: 2028-06-28

Conditions

T Lymphoblastic Leukemia/Lymphoma
Acute Myeloid Leukemia (AML)

Interventions

BIOLOGICAL

No Results Yet

NCT07151443 | RECRUITING | NA

60 participants

Comparison of Conventional and Retroclavicular Approaches for Ultrasound-guided Infraclavicular Brachial Plexus Block

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-09-15
Completion:: 2026-06-05

Conditions

Peripheral Nerve Block
Pain Management
Forearm Surgery
Hand Surgery
Upper Extremity

Interventions

PROCEDURE

No Results Yet

NCT07135687 | NOT_YET_RECRUITING | PHASE4

144 participants

Study to Use Oral Losartan to Decrease the Risk of Postoperative Scarring Following (ACL) Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2026-08-31
Completion:: 2028-10-31

Conditions

ACL Injury
ACL Reconstruction
Scar Formation

Interventions

DRUG
OTHER

No Results Yet

NCT07127042 | RECRUITING | PHASE2

270 participants

Study on BT-114143 Reducing Perioperative Bleeding in Total Knee Arthroplasty（TKA）

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-08-27
Completion:: 2026-12-31

Conditions

Total Knee Arthroplasty

Interventions

DRUG

No Results Yet

NCT07118085 | RECRUITING | PHASE1

56 participants

A Randomized, Double-blind, Placebo-controlled, Single and Multiple Dose Escalation Phase I Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of IMC-003 for Injection in Healthy Postmenopausal Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-08-18
Completion:: 2027-05-20

Conditions

Healthy Postmenopausal Women

Interventions

DRUG

No Results Yet

NCT07110376 | RECRUITING | NA

10 participants

Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-11-22
Completion:: 2026-07-01

Conditions

Parkinson Disease

Interventions

OTHER

No Results Yet

NCT07108322 | COMPLETED | NA

26 participants

Digital Versus Conventional Impression in Edentulous Patients With Flabby Ridge.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2023-03-30
Completion:: 2025-04-29

Conditions

Flabby Ridge
Edentulous Alveolar Ridge

Interventions

OTHER

No Results Yet

NCT07108205 | COMPLETED

126 participants

Image Quality Study of Spectral Precise Image CT 7700

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-07-16
Completion:: 2025-10-14

Conditions

Head
Body
Cardiac

Interventions

DEVICE

No Results Yet

NCT07102290 | COMPLETED | NA

4171 participants

Pragmatic Trial of Text Messages to Recruit Unassisted Tobacco Users Into Quitline Service

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2022-04-01
Completion:: 2022-05-01

Conditions

Smoking Cessation Counselling

Interventions

BEHAVIORAL

No Results Yet

NCT07097480 | RECRUITING | NA

80 participants

Virus Transmission to People Recently Bitten or With a History of Monkey Bites "SIMVIR

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-08-14
Completion:: 2026-12-31

Conditions

Bites Monkey

Interventions

PROCEDURE

No Results Yet

NCT07067580 | RECRUITING | NA

60 participants

Effect of Breathing Exercise on Pain and Quality of Recovery in After Transplantation Patients: A Randomized Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-08-01
Completion:: 2026-03-31

Conditions

Transplantation
Pain Management
Quality of Recovery 40

Interventions

OTHER

No Results Yet

NCT07062952 | RECRUITING | NA

200 participants

Kidney-protective Intervention With Salt Substitute After Kidney Tumor Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-04-24
Completion:: 2027-07-01

Conditions

Kidney Tumors
CKD
Salt Substitute
Nephrectomy
eGFR

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07062107 | ACTIVE_NOT_RECRUITING | NA

320 participants

Study on the Application of Adaptive Fluidics Technology in Lens Diseases Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-07-20
Completion:: 2029-12-31

Conditions

Lens Diseases

Interventions

PROCEDURE

No Results Yet

NCT07052695 | RECRUITING | PHASE1/PHASE2

40 participants

Mosunetuzumab for CLL MRD Clearance

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-11-24
Completion:: 2028-12-31

Conditions

Leukemia
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Lymphoma

Interventions

DRUG

No Results Yet

NCT07051525 | RECRUITING | NA

214 participants

Early Versus Late Stopping of Antibiotics in Adults With High-risk Hematological Malignancies/Receiving Cellular Therapies and Fever

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-12-03
Completion:: 2027-12-05

Conditions

Leukemia
CART Therapy
Transplantation, Stem Cell
Infections, Bacterial

Interventions

DRUG

No Results Yet

NCT07048483 | COMPLETED | NA

62 participants

Researching Engagement With Educational Lifestyle Content

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-07-07
Completion:: 2025-11-19

Conditions

Diet Quality

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT07043543 | NOT_YET_RECRUITING | NA

120 participants

Evaluation of the Clinical Utility of Online Adaptive Radiotherapy in Bladder Cancer (BLADAPT-GETUG V11)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2026-01-15
Completion:: 2029-01-30

Conditions

Bladder Cancer

Interventions

RADIATION

No Results Yet

NCT07017205 | NOT_YET_RECRUITING | NA

72 participants

Microaspiration and Endotracheal Tubes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2026-02-01
Completion:: 2026-04-30

Conditions

Endotracheal Tube Cuff
Microaspiration
Endotracheal Tube Cuff Pressure

Interventions

DEVICE

No Results Yet

NCT07008599 | COMPLETED | NA

83 participants

Assessment of Inflammatory Biomarkers in Molar-Incisor Hypomineralization-Affected First Permanent Molars

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2024-03-04
Completion:: 2024-11-26

Conditions

Molar-Incisor Hypomineralization (MIH)
Pulp Disease, Dental
Inflamation

Interventions

OTHER

No Results Yet

NCT07006493 | RECRUITING | NA

124 participants

REFINE-HCM: Intramyocardial Septal Radiofrequency Ablation for Obstructive Hypertrophic Cardiomyopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-07-20
Completion:: 2026-12-30

Conditions

Hypertrophic Cardiomyopathy, Obstructive

Interventions

DEVICE

No Results Yet

NCT07002905 | COMPLETED | PHASE2

125 participants

A Study to Evaluate the Efficacy, Safety, and Tolerability in Participants With Obesity or Overweight With Weight-Related Comorbidities

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-07-03
Completion:: 2025-12-08

Conditions

Chronic Weight Management

Interventions

DRUG

No Results Yet

NCT07000955 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

98 participants

Tolerance and Pharmacokinetic/Pharmacokinetic Study of IBI362 15mg in Patients With Moderate to Severe Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-06-17
Completion:: 2026-09-30

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT06997575 | COMPLETED | PHASE4

200 participants

Comparing Intravenous and Intramuscular Magnesium Sulphate for Preventing Seizure Recurrence in Women With Eclampsia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-05-13
Completion:: 2025-11-12

Conditions

Eclampsia
Seizures
Pregnancy

Interventions

DRUG

No Results Yet

NCT06995638 | RECRUITING | NA

130 participants

Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-12-10
Completion:: 2027-12-31

Conditions

Healthy Aging
Alzheimer's Disease (AD)

Interventions

BEHAVIORAL

No Results Yet

NCT06980974 | WITHDRAWN | NA

0 participants

Acceptance and Commitment Therapy for Chemsex

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-12-01
Completion:: 2030-07-31

Conditions

Chemsex

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06973837 | RECRUITING

80 participants

Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-10-03
Completion:: 2026-10-31

Conditions

Chronic Low Back Pain (CLBP)
Chronic Insomnia
Neuroinflammation

Interventions

OTHER

No Results Yet

NCT06967558 | RECRUITING | PHASE2

60 participants

The Role of Islet GLP-1 in the Pathogenesis of Prediabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-11-01
Completion:: 2027-10-30

Conditions

PreDiabetes

Interventions

BIOLOGICAL

No Results Yet

NCT06967025 | COMPLETED | PHASE2

60 participants

Ischemic Postconditioning in Acute Stroke Patients Receiving Endovascular Thrombectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2024-09-12
Completion:: 2025-08-15

Conditions

Stroke Acute
Cytoprotection
Ischemic Conditioning

Interventions

PROCEDURE

No Results Yet

NCT06955598 | COMPLETED | PHASE1

30 participants

A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Subcutaneous Injections of SHR-2173 in Patients With Systemic Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2024-11-24
Completion:: 2025-11-10

Conditions

Systemic Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT06946550 | RECRUITING | NA

5 participants

Non-Ablative Laser to Treat Scarring Alopecia With Hair Follicle Gene Expression Analysis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-12-09
Completion:: 2027-12-31

Conditions

Scarring Alopecia

Interventions

DEVICE

No Results Yet

NCT06939842 | COMPLETED | NA

102 participants

The Effect of Menthol Ice and Frozen Saline Applications After Lumbar Disc Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-04-15
Completion:: 2025-10-15

Conditions

Thirst
Sore Throat

Interventions

OTHER

No Results Yet

NCT06939166 | RECRUITING | EARLY_PHASE1

12 participants

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/B Cell Maturation Antigen （CD19/BCMA） in Patients With r/r Neurological Autoimmune Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-06-17
Completion:: 2026-04-30

Conditions

Neuromyelitis Optica Spectrum Disorders
Myasthenia Gravis
Multiple Sclerosis
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Autoimmune Encephalitis

Interventions

DRUG

No Results Yet

NCT06934577 | RECRUITING | NA

900 participants

Michigan Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (SIGHT) 2

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-12-04
Completion:: 2030-08-31

Conditions

Eye Diseases
Visual Impairment
Glaucoma

Interventions

OTHER

No Results Yet

NCT06930664 | COMPLETED | PHASE1

146 participants

A Study of Sotatercept (MK-7962) in Healthy Females Administered as a Liquid Formulation in an Autoinjector Versus the Lyophilized Formulation (MK-7962-027)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-05-16
Completion:: 2025-11-11

Conditions

Healthy

Interventions

BIOLOGICAL

No Results Yet

NCT06923618 | RECRUITING | NA

385 participants

Cancer of the Lung And SeneScencE - Prospective Cohort 1

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-07-09
Completion:: 2028-07-31

Conditions

Non-Small Cell Lung Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT06920602 | COMPLETED | NA

49 participants

AI Chatbot for Migraine Management in Hong Kong Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-15
Start Date:: 2025-07-01
Completion:: 2025-11-01

Conditions

Migraine

Interventions

DEVICE

No Results Yet