Clinical Trials Updated in 2025

NCT06280755 | RECRUITING

7000 participants

Clinical Impact Through AI-assisted MS Care - A Retrospective Multi-center Observational Study.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-03-01
Completion:: 2027-04-30

Conditions

Multiple Sclerosis
NMO Spectrum Disorder
Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease
Radiologically Isolated Syndrome
Clinically Isolated Syndrome

No Results Yet

NCT06279871 | COMPLETED | PHASE3

1514 participants

Immunogenicity and Safety Study of Self-amplifying mRNA COVID-19 Vaccine Administered With Influenza Vaccines in Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-03-27
Completion:: 2024-10-09

Conditions

COVID-19

Interventions

BIOLOGICAL
OTHER

Results Available

NCT06228560 | COMPLETED | PHASE2

202 participants

Efficacy and Safety of LP-003 in Patients With CSU Who Remain Symptomatic Despite Antihistamine (H1) Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-01-26
Completion:: 2025-04-17

Conditions

Chronic Spontaneous Urticaria

Interventions

BIOLOGICAL

No Results Yet

NCT06200571 | ENROLLING_BY_INVITATION

200 participants

Biological Changes Associated With High Risk of Preeclampsia in Nulliparous Women

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-05-22
Completion:: 2026-12-31

Conditions

Preeclampsia

No Results Yet

NCT06200545 | COMPLETED | NA

199 participants

Improving HIV Prevention Among Heterosexual Men Seeking STI Services in Malawi

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-04-02
Completion:: 2025-07-28

Conditions

HIV Infection
Sexually Transmitted Infections
Pre-exposure Prophylaxis
Systems Navigation

Interventions

OTHER
DIAGNOSTIC_TEST
BEHAVIORAL

No Results Yet

NCT06179329 | RECRUITING | NA

150 participants

One-year Patency Comparison Between Radial Artery and No-touch Saphenous Vein Grafts in Women Undergoing Isolated CABG

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-01-01
Completion:: 2025-01-01

Conditions

Cardiac Disease
Surgery-Complications
Graft Failure

Interventions

PROCEDURE

No Results Yet

NCT06179199 | NOT_YET_RECRUITING | NA

40 participants

Evaluation of the Analgesic Effect of Transcranial Direct Current Stimulation (tDCS) for Sedated Patients in Intensive Care Unit.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2026-01-31
Completion:: 2026-09-30

Conditions

Transcranial Direct Current Stimulation (tDCS)

Interventions

DEVICE

No Results Yet

NCT06150716 | RECRUITING | PHASE1

24 participants

Orbit Study: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Intrathecally Administered ION356 in Participants With Pelizaeus Merzbacher Disease (PMD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-04-10
Completion:: 2028-06-30

Conditions

Pelizaeus-Merzbacher Disease

Interventions

DRUG

No Results Yet

NCT06145477 | RECRUITING

160 participants

Parenting for Tomorrow: A New Model for Supporting Preschool Children's Mental Health in Head Start

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-11-15
Completion:: 2028-11-30

Conditions

Parenting
Parenting Intervention

Interventions

BEHAVIORAL

No Results Yet

NCT06143865 | COMPLETED | NA

67 participants

Closed Aspiration on Hemodynamic Changes and Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-07-10
Completion:: 2022-11-10

Conditions

Aspiration

Interventions

PROCEDURE

No Results Yet

NCT06140368 | COMPLETED | NA

84 participants

Virtual Realityon Pain, Anxiety and Comfort During Trigger Point Injection

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-05-10
Completion:: 2023-08-10

Conditions

Virtual Reality

Interventions

BEHAVIORAL

No Results Yet

NCT06107413 | ACTIVE_NOT_RECRUITING | PHASE2

280 participants

Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-11-12
Completion:: 2026-12-31

Conditions

Unresectable Metastatic Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT06102096 | COMPLETED | NA

125 participants

Culturally Adapted iCBT for Arabic-speaking Refugee and Migrant Youth With Common Mental Health Problems

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-11-27
Completion:: 2025-08-31

Conditions

Depressive Symptoms
Anxiety
Insomnia
Grief
Psychological Trauma
Resilience
Stress
Marital Relationship
Psychological Well-Being

Interventions

BEHAVIORAL

No Results Yet

NCT06102044 | RECRUITING | PHASE3

3250 participants

Zinc Supplementation for Young Infants With Clinical Severe Infection in Tanzania

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-12-27
Completion:: 2027-10-30

Conditions

Neonatal Infection

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06079775 | COMPLETED | PHASE1

53 participants

P1, DDI & MAD PK and Safety Study of Xeruborbactam Oral Prodrug in Combo With Ceftibuten in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-01-30
Completion:: 2025-01-05

Conditions

Bacterial Infections

Interventions

DRUG

No Results Yet

NCT06079697 | COMPLETED | NA

52 participants

An Exercise Prehabilitation Intervention for Improving Mobility and Recovery Outcomes in Patients Undergoing Head and Neck Cancer Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-02-01
Completion:: 2025-07-15

Conditions

Head and Neck Carcinoma

Interventions

OTHER

No Results Yet

NCT06065384 | RECRUITING | NA

44 participants

Neural Plasticity and Motor Recovery After Upper Extremity Motor Training in People With c-SCI

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-10-09
Completion:: 2027-03-28

Conditions

Spinal Cord Injuries

Interventions

OTHER

No Results Yet

NCT06062901 | COMPLETED | NA

28 participants

An Educational Intervention on Provider Knowledge for the Support of Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2021-09-17
Completion:: 2023-09-19

Conditions

Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm

Interventions

OTHER

No Results Yet

NCT06024915 | COMPLETED | PHASE1

40 participants

A Study to Evaluate Drug-Drug Interaction of TQ05105 Tablets

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-09-21
Completion:: 2024-01-29

Conditions

Myelofibrosis

Interventions

DRUG

No Results Yet

NCT06002100 | ENROLLING_BY_INVITATION

540 participants

Prediction of REsponse to Depression Interventions Using Clinical and TD-fNIRS Measurements

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-08-14
Completion:: 2026-08-31

Conditions

Depression
Major Depressive Disorder

Interventions

OTHER

No Results Yet

NCT05993728 | ACTIVE_NOT_RECRUITING | NA

441 participants

Virtual Body Project Groups Led by Peers Versus Clinicians

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-02-15
Completion:: 2027-12-31

Conditions

Eating Disorders
Body Image

Interventions

BEHAVIORAL

No Results Yet

NCT05970471 | COMPLETED

167 participants

Preferences of Patients Treated With Oral Cancer Drugs and Informal Caregivers for Pharmaceutical Consultation in Hospital

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-08-10
Completion:: 2025-12-04

Conditions

Preference, Patient
Pharmacist-Patient Relations
Caregiver
Cancer

No Results Yet

NCT05925608 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

39 participants

Clinical Trial of Human Allogenic Culture-expanded Bone Marrow-derived Mesenchymal Stem Cells

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-08-23
Completion:: 2026-12-31

Conditions

Heart Failure, Systolic

Interventions

COMBINATION_PRODUCT
DIAGNOSTIC_TEST

No Results Yet

NCT05920083 | TERMINATED | NA

65 participants

Obstructive Sleep Apnea - Autonomic and Vascular Exploration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-01-12
Completion:: 2024-09-11

Conditions

Obstructive Sleep Apnea

Interventions

OTHER

No Results Yet

NCT05894876 | TERMINATED

43 participants

A Study of the Genetic Basis of Response to Growth Hormone Treatment in Children With Idiopathic Short Stature

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-04-29
Completion:: 2025-03-21

Conditions

Idiopathic Short Stature

Interventions

OTHER

No Results Yet

NCT05887297 | COMPLETED | NA

35 participants

Impact of Cognitive Behavioural Therapy for Insomnia on Endocrine Therapy Adherence

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-03-23
Completion:: 2024-04-23

Conditions

Insomnia
Breast Cancer
Adherence, Medication
Quality of Life
Survivorship

Interventions

BEHAVIORAL

No Results Yet

NCT05874895 | COMPLETED | NA

24 participants

MAnual Lymphatic DrAinage to iMprove the outcomE of Patients After Septic Shock

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-06-01
Completion:: 2024-05-31

Conditions

Sepsis
Multiorgan Failure
Inflammatory Response
Septic Shock

Interventions

PROCEDURE

No Results Yet

NCT05840081 | COMPLETED | NA

37 participants

Dairy Fat and Fermentation Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-10-01
Completion:: 2025-08-19

Conditions

Heart Diseases
Microbial Colonization
Inflammation

Interventions

OTHER

No Results Yet

NCT05829733 | RECRUITING | NA

70 participants

6-month Efficacy and Safety of Synolis VA 80/160 in Hip Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-05-27
Completion:: 2027-04-30

Conditions

Osteoarthritis, Hip

Interventions

DEVICE

No Results Yet

NCT05676476 | RECRUITING | NA

132 participants

The ACHIEVE Trial: Achieving Longer Gestation in Preeclampsia Via Antihypertensive Therapy.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-02-14
Completion:: 2026-12-31

Conditions

Preeclampsia
Gestational Hypertension
Hypertensive Disorder of Pregnancy

Interventions

DRUG

No Results Yet

NCT05628688 | COMPLETED

67 participants

A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Insight® Pro Device for Evaluating Lymphatic and Venous Disorders (VOLGA)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-08-08
Completion:: 2024-08-28

Conditions

Lymphedema
Chronic Venous Insufficiency
Edema
Venous Insufficiency of Leg

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05625204 | RECRUITING | NA

200 participants

High Intensity Interval Training (HIIT) to Reduce Frailty and Enhance Resilience in Older Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-01-29
Completion:: 2027-07-01

Conditions

Frailty

Interventions

BEHAVIORAL

No Results Yet

NCT05611905 | COMPLETED

13 participants

Biodistribution and Pathophysiology Study of 11C-para-aminobenzoic Acid

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-12-22
Completion:: 2025-11-08

Conditions

Renal Excretion
Bacterial Infections
Inflammatory Disease
Oncologic Disease

Interventions

COMBINATION_PRODUCT
DRUG

No Results Yet

NCT05611892 | COMPLETED

16 participants

Biodistribution and Pathophysiology Study of 18F-Fluorodeoxysorbitol (18F-FDS) in Diseased Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-12-22
Completion:: 2025-10-28

Conditions

Enterobacterial Infections
Oncologic Disease
Inflammatory Disease
Invasive Fungal Infections

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05609552 | COMPLETED

10 participants

Biodistribution and Pharmacokinetics of Pretomanid in Tuberculosis Patients Using 18F-Pretomanid PET

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-05-22
Completion:: 2025-10-28

Conditions

Tuberculosis

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05564104 | COMPLETED | PHASE1

32 participants

A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Works in Participants With Reduced Liver Function and in Healthy Participants With Normal Liver Function and How Cagrilintide is Absorbed and Used by the Body

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-04-05
Completion:: 2024-09-06

Conditions

Hepatic Impairment
Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT05541666 | COMPLETED | NA

80 participants

Effect of Emotional Freedom Technique on Postoperative Pain and Anxiety in Patients Undergoing Total Knee Replacement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-03-07
Completion:: 2022-09-15

Conditions

Total Knee Arthroplasty

Interventions

OTHER

No Results Yet

NCT05536609 | RECRUITING | NA

166 participants

Cast Or ePineural Suture for Digital Nerve Injuries - a Randomised Controlled Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-08-29
Completion:: 2030-12-31

Conditions

Digital Nerve Injury

Interventions

PROCEDURE

No Results Yet

NCT05507346 | COMPLETED | NA

121 participants

A Clinical Study to Evaluate the Effectiveness of a Novel Portable Non-Pneumatic Active Compression Device vs. an Advanced Pneumatic Compression Device for Treating Lower Extremity Lymphedema

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-09-06
Completion:: 2024-01-09

Conditions

Lymphedema
Lymphedema of Leg
Chronic Venous Insufficiency
Venous Insufficiency
Lymphedema, Lower Limb

Interventions

DEVICE

No Results Yet

NCT05486065 | COMPLETED | PHASE2

245 participants

A Research Study to Look Into How Well Semaglutide Medicine Works at Different Doses in People With Type 2 Diabetes and Overweight

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-08-08
Completion:: 2023-10-12

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

Results Available