Clinical Trials Updated in 2025

NCT06024915 | COMPLETED | PHASE1

40 participants

A Study to Evaluate Drug-Drug Interaction of TQ05105 Tablets

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-09-21
Completion:: 2024-01-29

Conditions

Myelofibrosis

Interventions

DRUG

No Results Yet

NCT06002100 | ENROLLING_BY_INVITATION

540 participants

Prediction of REsponse to Depression Interventions Using Clinical and TD-fNIRS Measurements

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-08-14
Completion:: 2026-08-31

Conditions

Depression
Major Depressive Disorder

Interventions

OTHER

No Results Yet

NCT05993728 | ACTIVE_NOT_RECRUITING | NA

441 participants

Virtual Body Project Groups Led by Peers Versus Clinicians

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-02-15
Completion:: 2027-12-31

Conditions

Eating Disorders
Body Image

Interventions

BEHAVIORAL

No Results Yet

NCT05970471 | COMPLETED

167 participants

Preferences of Patients Treated With Oral Cancer Drugs and Informal Caregivers for Pharmaceutical Consultation in Hospital

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-08-10
Completion:: 2025-12-04

Conditions

Preference, Patient
Pharmacist-Patient Relations
Caregiver
Cancer

No Results Yet

NCT05925608 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

39 participants

Clinical Trial of Human Allogenic Culture-expanded Bone Marrow-derived Mesenchymal Stem Cells

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-08-23
Completion:: 2026-12-31

Conditions

Heart Failure, Systolic

Interventions

COMBINATION_PRODUCT
DIAGNOSTIC_TEST

No Results Yet

NCT05920083 | TERMINATED | NA

65 participants

Obstructive Sleep Apnea - Autonomic and Vascular Exploration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-01-12
Completion:: 2024-09-11

Conditions

Obstructive Sleep Apnea

Interventions

OTHER

No Results Yet

NCT05894876 | TERMINATED

43 participants

A Study of the Genetic Basis of Response to Growth Hormone Treatment in Children With Idiopathic Short Stature

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-04-29
Completion:: 2025-03-21

Conditions

Idiopathic Short Stature

Interventions

OTHER

No Results Yet

NCT05887297 | COMPLETED | NA

35 participants

Impact of Cognitive Behavioural Therapy for Insomnia on Endocrine Therapy Adherence

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-03-23
Completion:: 2024-04-23

Conditions

Insomnia
Breast Cancer
Adherence, Medication
Quality of Life
Survivorship

Interventions

BEHAVIORAL

No Results Yet

NCT05874895 | COMPLETED | NA

24 participants

MAnual Lymphatic DrAinage to iMprove the outcomE of Patients After Septic Shock

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-06-01
Completion:: 2024-05-31

Conditions

Sepsis
Multiorgan Failure
Inflammatory Response
Septic Shock

Interventions

PROCEDURE

No Results Yet

NCT05840081 | COMPLETED | NA

37 participants

Dairy Fat and Fermentation Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-10-01
Completion:: 2025-08-19

Conditions

Heart Diseases
Microbial Colonization
Inflammation

Interventions

OTHER

No Results Yet

NCT05829733 | RECRUITING | NA

70 participants

6-month Efficacy and Safety of Synolis VA 80/160 in Hip Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-05-27
Completion:: 2027-04-30

Conditions

Osteoarthritis, Hip

Interventions

DEVICE

No Results Yet

NCT05676476 | RECRUITING | NA

132 participants

The ACHIEVE Trial: Achieving Longer Gestation in Preeclampsia Via Antihypertensive Therapy.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-02-14
Completion:: 2026-12-31

Conditions

Preeclampsia
Gestational Hypertension
Hypertensive Disorder of Pregnancy

Interventions

DRUG

No Results Yet

NCT05628688 | COMPLETED

67 participants

A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Insight® Pro Device for Evaluating Lymphatic and Venous Disorders (VOLGA)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-08-08
Completion:: 2024-08-28

Conditions

Lymphedema
Chronic Venous Insufficiency
Edema
Venous Insufficiency of Leg

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05625204 | RECRUITING | NA

200 participants

High Intensity Interval Training (HIIT) to Reduce Frailty and Enhance Resilience in Older Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-01-29
Completion:: 2027-07-01

Conditions

Frailty

Interventions

BEHAVIORAL

No Results Yet

NCT05611905 | COMPLETED

13 participants

Biodistribution and Pathophysiology Study of 11C-para-aminobenzoic Acid

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-12-22
Completion:: 2025-11-08

Conditions

Renal Excretion
Bacterial Infections
Inflammatory Disease
Oncologic Disease

Interventions

COMBINATION_PRODUCT
DRUG

No Results Yet

NCT05611892 | COMPLETED

16 participants

Biodistribution and Pathophysiology Study of 18F-Fluorodeoxysorbitol (18F-FDS) in Diseased Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-12-22
Completion:: 2025-10-28

Conditions

Enterobacterial Infections
Oncologic Disease
Inflammatory Disease
Invasive Fungal Infections

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05609552 | COMPLETED

10 participants

Biodistribution and Pharmacokinetics of Pretomanid in Tuberculosis Patients Using 18F-Pretomanid PET

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-05-22
Completion:: 2025-10-28

Conditions

Tuberculosis

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05564104 | COMPLETED | PHASE1

32 participants

A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Works in Participants With Reduced Liver Function and in Healthy Participants With Normal Liver Function and How Cagrilintide is Absorbed and Used by the Body

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-04-05
Completion:: 2024-09-06

Conditions

Hepatic Impairment
Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT05541666 | COMPLETED | NA

80 participants

Effect of Emotional Freedom Technique on Postoperative Pain and Anxiety in Patients Undergoing Total Knee Replacement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-03-07
Completion:: 2022-09-15

Conditions

Total Knee Arthroplasty

Interventions

OTHER

No Results Yet

NCT05539430 | ACTIVE_NOT_RECRUITING | PHASE1

56 participants

Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-04-18
Completion:: 2027-12-31

Conditions

Gastric Cancer
Gastroesophageal-junction Cancer
Esophageal Cancer
Pancreatic Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT05536609 | RECRUITING | NA

166 participants

Cast Or ePineural Suture for Digital Nerve Injuries - a Randomised Controlled Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-08-29
Completion:: 2030-12-31

Conditions

Digital Nerve Injury

Interventions

PROCEDURE

No Results Yet

NCT05507346 | COMPLETED | NA

121 participants

A Clinical Study to Evaluate the Effectiveness of a Novel Portable Non-Pneumatic Active Compression Device vs. an Advanced Pneumatic Compression Device for Treating Lower Extremity Lymphedema

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-09-06
Completion:: 2024-01-09

Conditions

Lymphedema
Lymphedema of Leg
Chronic Venous Insufficiency
Venous Insufficiency
Lymphedema, Lower Limb

Interventions

DEVICE

No Results Yet

NCT05486065 | COMPLETED | PHASE2

245 participants

A Research Study to Look Into How Well Semaglutide Medicine Works at Different Doses in People With Type 2 Diabetes and Overweight

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-08-08
Completion:: 2023-10-12

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

Results Available

NCT05478252 | COMPLETED | PHASE3

388 participants

A Research Study to Compare Two Semaglutide Medicines in People With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-08-03
Completion:: 2023-08-09

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

Results Available

NCT05458128 | COMPLETED | PHASE3

119 participants

A Long-Term Safety and Effectiveness Study to Evaluate Pitolisant in Adult Patients With Idiopathic Hypersomnia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-08-19
Completion:: 2025-10-01

Conditions

Idiopathic Hypersomnia
Excessive Daytime Sleepiness

Interventions

DRUG

No Results Yet

NCT05450432 | RECRUITING | PHASE4

100 participants

Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-10-13
Completion:: 2026-06-01

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT05444556 | COMPLETED | PHASE1

113 participants

A Study of Imlunestrant (LY3484356) in Female Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-07-07
Completion:: 2022-11-02

Conditions

Healthy

Interventions

DRUG

Results Available

NCT05433584 | ACTIVE_NOT_RECRUITING | PHASE4

780 participants

A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-08-01
Completion:: 2025-10-21

Conditions

Type 2 Diabetes

Interventions

DRUG

No Results Yet

NCT05421689 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

66 participants

Autologous Muscle Derived Cells for Treatment of Tongue Dysphagia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-05-26
Completion:: 2026-12-31

Conditions

Oropharyngeal Dysphagia

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT05392114 | ACTIVE_NOT_RECRUITING | PHASE3

154 participants

A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-07-13
Completion:: 2026-12-31

Conditions

Hereditary Angioedema

Interventions

DRUG

No Results Yet

NCT05389436 | COMPLETED | NA

86 participants

Outpatient Versus Inpatient Surgery for Ankle Fractures

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-05-23
Completion:: 2025-03-20

Conditions

Ankle Fractures
Orthopedic Procedures
Surgical Procedures
Inpatient

Interventions

PROCEDURE

No Results Yet

NCT05354232 | RECRUITING | NA

60 participants

Home-based Transcranial Direct Current Stimulation (tDCS) for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-07-01
Completion:: 2026-05-31

Conditions

Attention Deficit Disorder
Attention Deficit Disorder With Hyperactivity

Interventions

DEVICE

No Results Yet

NCT05299944 | COMPLETED | PHASE2

126 participants

Reducing Pain and Opioid Use With CBD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-03-08
Completion:: 2025-07-29

Conditions

Opioid Use Disorder

Interventions

DRUG

No Results Yet

NCT05224544 | COMPLETED | NA

43 participants

Intermittent Catheterisation on the Bladder Mucosa of Healthy Volunteers With a Prototype Micro Hole Zone Catheter

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-01-31
Completion:: 2022-03-31

Conditions

Urinary Incontinence

Interventions

DEVICE

Results Available

NCT05185843 | ACTIVE_NOT_RECRUITING | PHASE3

24 participants

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-02-25
Completion:: 2027-06-30

Conditions

Familial Chylomicronemia Syndrome

Interventions

DRUG

No Results Yet

NCT05182073 | COMPLETED | PHASE1

31 participants

FT576 in Subjects With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2021-11-10
Completion:: 2024-09-20

Conditions

Multiple Myeloma
Myeloma

Interventions

DRUG

No Results Yet

NCT05168774 | COMPLETED | PHASE1/PHASE2

20 participants

FRDA Investigator Initiated Study (IIS) With Elamipretide

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-03-03
Completion:: 2024-06-25

Conditions

Friedreich Ataxia

Interventions

DRUG

Results Available

NCT05130450 | ACTIVE_NOT_RECRUITING | PHASE3

60 participants

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Participants With Familial Chylomicronemia Syndrome (FCS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2021-11-18
Completion:: 2028-02-29

Conditions

Familial Chylomicronemia Syndrome

Interventions

DRUG

No Results Yet

NCT05122767 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

92 participants

Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment (DOLPHIN KIDS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-05-24
Completion:: 2025-07-04

Conditions

Tuberculosis
HIV

Interventions

DRUG

No Results Yet

NCT05122026 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

252 participants

Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIV

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-01-17
Completion:: 2025-10-24

Conditions

HIV Seropositivity
Pregnancy
Tuberculosis Infection

Interventions

DRUG

No Results Yet