Clinical Trials Updated in 2025

NCT07277452 | NOT_YET_RECRUITING | PHASE2

156 participants

Nimotuzumab Combined With Nab-paclitaxel/Gemcitabine in the Perioperative Treatment of High-risk Resectable/Borderline Resectable Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-12-10
Completion:: 2028-12-10

Conditions

Pancreatic Cancer, Adult

Interventions

DRUG

No Results Yet

NCT07277426 | NOT_YET_RECRUITING | NA

342 participants

Comparing Two Surgical Methods to Prevent Pterygium Regrowth

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2026-02-02
Completion:: 2026-07-02

Conditions

Pterygium

Interventions

PROCEDURE

No Results Yet

NCT07277400 | NOT_YET_RECRUITING

800 participants

Development and Validation of a Cardiac Magnetic Resonance-Based Multimodal Deep Learning Model for Long-Term Outcome Prediction in ST-Segment Elevation Myocardial Infarction

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-11
Start Date:: 2026-01-31
Completion:: 2026-02-28

Conditions

ST Elevation (STEMI) Myocardial Infarction

No Results Yet

NCT07277374 | COMPLETED

24 participants

Comparison of a Torso-Based Derived 6-Lead Electrocardiogram (ECG) Device With Standard 12-Lead Electrocardiogram (ECG) in Healthy Volunteers

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-11
Start Date:: 2023-12-06
Completion:: 2024-03-06

Conditions

Healthy Volunteer

Interventions

DEVICE

No Results Yet

NCT07277361 | RECRUITING

100 participants

Study of the Quality of Life of Patients With Fabry Disease Aged 65 and Over With and Without Specific Treatment

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-11
Start Date:: 2024-10-08
Completion:: 2029-10-14

Conditions

Fabry Disease
Aged 65 Years or Older
Alpha Galactosidase A Deficiency
Galactosidase A Gene Mutation

No Results Yet

NCT07277348 | NOT_YET_RECRUITING | NA

60 participants

Analysis of The Outcomes of Therapeutic Photorefractive Keratectomy Combined With Prophylactic Accelerated Cross-Linking (PRK-Plus), for Treatment of Thin Suspicious Cornea

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2026-02-01
Completion:: 2027-01-31

Conditions

Thin Suspicious Cornea

Interventions

PROCEDURE

No Results Yet

NCT07277335 | RECRUITING

50 participants

Neuromuscular Variables and Performance in Mexican Weightlifters

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-12-27
Completion:: 2025-12-30

Conditions

Isometric Muscle Strength
Jumping Performance
Weightlifting
Performance Measures

Interventions

OTHER

No Results Yet

NCT07277296 | NOT_YET_RECRUITING | NA

103 participants

CGUARDIANS III IDE Pivotal Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2026-01-01
Completion:: 2027-02-01

Conditions

Carotid Artery Stenosis

Interventions

DEVICE

No Results Yet

NCT07277283 | COMPLETED | PHASE4

34 participants

Nicardipine vs. Labetalol

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-02-01
Completion:: 2025-07-01

Conditions

Acute Ischemic Stroke
Hypertensive Crisis

Interventions

DRUG

No Results Yet

NCT07277218 | NOT_YET_RECRUITING | NA

578 participants

Drug-coated Balloons Versus Drug-eluting Stents for the Treatment of Femoropopliteal In-Stent Restenosis: A Prospective, Multicenter, Cohort Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2026-01-01
Completion:: 2028-01-01

Conditions

Femoropopliteal In-Stent Restenosis (ISR)

Interventions

PROCEDURE

No Results Yet

NCT07277205 | NOT_YET_RECRUITING | NA

45 participants

Comparison of Vestibular and Dual-Task Rehabilitation in Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2026-01-31
Completion:: 2027-06-30

Conditions

Parkinson Disease

Interventions

OTHER

No Results Yet

NCT07277192 | COMPLETED

562 participants

HAIC vs. TACE Combined With ICIs and TKIs in Intermediate-to-Advanced HCC: A Multicenter Study on Liver Injury and Survival

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-11
Start Date:: 2023-10-01
Completion:: 2024-12-31

Conditions

Hepatecellular Carcinoma
Liver Injury
HAIC(Hepatic Artery Infusion Chemotherapy)
TACE(Transcatheter Arterial Chemoembolization)

No Results Yet

NCT07277179 | COMPLETED | PHASE3

113 participants

Evaluate the Efficacy, Safety, and Pharmacokinetic Profile and Immunogenicity of Subcutaneous Netakimab in Chinese Adult Patients With Active Ankylosing Spondylitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2023-03-20
Completion:: 2024-07-05

Conditions

Ankylosing Spondylitis

Interventions

DRUG

No Results Yet

NCT07277166 | RECRUITING | NA

20 participants

The Effect of Mobile Robot Assisted Gait Training on Gait Performance in Chronic Patients With Impaired Gait Function After Burn Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-05-13
Completion:: 2026-11-15

Conditions

Burns
Gait Dysfunction
Robot Training

Interventions

OTHER

No Results Yet

NCT07277140 | NOT_YET_RECRUITING

300 participants

Impact of Iron Deficiency on Arrhythmic Events and Resting ECG Abnormalities in Patients Hospitalized With Heart Failure

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-12-15
Completion:: 2027-01-01

Conditions

Heart Failure
Iron Deficiency

No Results Yet

NCT07277088 | NOT_YET_RECRUITING | NA

158 participants

The Percutaneous Interventional Surgery Control System for Pulmonary Nodule Biopsy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-12-10
Completion:: 2027-05-30

Conditions

Pulmonary Nodules
Lung Cancer (Diagnosis)
Percutaneous Needle Biopsy
Transthoracic Needle Biopsy
Robotic Assisted Intervention

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07277075 | COMPLETED

50 participants

Probiotic Intervention and Its Influence on Serum Leucine-Rich Alpha-2 Glycoprotein 1 Levels in Acne Vulgaris Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-11
Start Date:: 2024-10-01
Completion:: 2025-09-30

Conditions

Probiotic
Influence
Serum Leucine-Rich Alpha-2 Glycoprotein 1
Acne Vulgaris

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07277062 | NOT_YET_RECRUITING | NA

77 participants

Optimisation and Evaluation of a Just-in-time Adaptive Intervention (JITAI) for Sleep and Circadian Problems (Phase I and II)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2026-01-01
Completion:: 2028-02-29

Conditions

Sleep and Circadian Problems

Interventions

BEHAVIORAL

No Results Yet

NCT07277049 | NOT_YET_RECRUITING | NA

80 participants

Optimisation and Evaluation of a Just-in-time Adaptive Intervention (JITAI) for Sleep and Circadian Problems (Phase III)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2026-01-01
Completion:: 2028-02-29

Conditions

Sleep and Circadian Problems

Interventions

BEHAVIORAL

No Results Yet

NCT07277036 | COMPLETED | NA

92 participants

Video-Assisted Education After Laparoscopic Cholecystectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2023-10-01
Completion:: 2024-01-10

Conditions

Laparoscopic Cholecystectomy
Patient Education

Interventions

BEHAVIORAL

No Results Yet

NCT07277023 | COMPLETED | NA

49 participants

The Influence of micro-and Macro Vascular Dysfunction on Clinical Severity in Adults With Sickle Cell Anemia (SS) and Sickle Cell Hemoglobin C Disease (SC)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2016-04-29
Completion:: 2018-10-29

Conditions

Sickle Cell Anemia

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07277010 | NOT_YET_RECRUITING

200 participants

AI Wound Alert & Home Management for Recurrent DFU

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-11
Start Date:: 2026-01-01
Completion:: 2028-06-30

Conditions

Diabetic Foot Ulcer (DFU)

Interventions

BEHAVIORAL

No Results Yet

NCT07276932 | RECRUITING | NA

106 participants

Clinical Study of Acupoint Application on Relieving qi Deficiency and Constipation in Patients Undergoing Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-07-16
Completion:: 2025-12-31

Conditions

Postoperative Chemotherapy
Chemotherapy

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT07276906 | NOT_YET_RECRUITING | PHASE4

300 participants

Comparing Intramuscular Fentanyl and Ketorolac With Nerve of Arnold (NOA) Block for Bilateral Myringotomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2026-01-31
Completion:: 2026-06-30

Conditions

Postoperative Pain

Interventions

DRUG
PROCEDURE

No Results Yet

NCT07276893 | COMPLETED | NA

42 participants

Preop Preparation Before Cardiac Catheterization

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-02-01
Completion:: 2025-09-01

Conditions

Cardiac Abnormalities
Preoperative Care
Children
Pediatric Nursing
Animation

Interventions

BEHAVIORAL

No Results Yet

NCT07276867 | RECRUITING | NA

58 participants

Intrathecal Dexmedetomidine-Fentanyl Combination Versus Fentanyl Alone as Adjuvant to Bupivacaine in Spinal Anesthesia for Above Knee Amputation in Sarcomas of Lower Extremity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-10-20
Completion:: 2026-04-01

Conditions

Intrathecal
Dexmedetomidine
Fentanyl
Bupivacaine
Spinal Anesthesia
Above Knee Amputation
Sarcomas
Lower Extremity

Interventions

DRUG

No Results Yet

NCT07276854 | NOT_YET_RECRUITING

32 participants

Novel Humanized Ferritin-based NIR Fluorescent Molecular Probe for Identifying Tumor Margins in Gastric Tissue

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-12-30
Completion:: 2026-07-30

Conditions

Gastric Cancer
Molecular Imaging

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07276841 | NOT_YET_RECRUITING | NA

11 participants

Digital Occlusal Analysis and Bite Force Evaluation of Primary Molars Restored With Zirconia Crowns Using T-Scan

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2026-01-31
Completion:: 2026-03-31

Conditions

Dental Occlusion
Primary Teeth
Pulp-treated Primary Molars
Zirconia Crowns

Interventions

PROCEDURE

No Results Yet

NCT07276763 | NOT_YET_RECRUITING

16509 participants

Impact of Discontinuing GLP-1 Receptor Agonists for Two Weeks Prior to Upper Endoscopy on the Risk of Gastric Retention

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-12-10
Completion:: 2025-12-15

Conditions

Gastric Retention

Interventions

OTHER

No Results Yet

NCT07276737 | NOT_YET_RECRUITING | PHASE2

37 participants

Preconditioning With a Combination of Thiotepa, Cyclophosphamide, and Busulfan for Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of NK/T-Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-12-30
Completion:: 2029-12-30

Conditions

NK T-Cell Lymphoma

Interventions

DRUG

No Results Yet

NCT07276698 | NOT_YET_RECRUITING | PHASE2

39 participants

Clinical Study on Maintenance Therapy With Selinexor Combined With Azacitidine After Allogeneic Hematopoietic Stem Cell Transplantation for NK/T-cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-12-30
Completion:: 2029-12-30

Conditions

NK T-Cell Lymphoma

Interventions

DRUG

No Results Yet

NCT07276685 | COMPLETED | NA

60 participants

Evaluation of the Success of TheraCal PT in Pulpotomy Treatment of Primary Teeth Using Low-Level Laser Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2023-01-05
Completion:: 2025-07-05

Conditions

Primary Tooth Pulpotomy
Vital Pulp Therapy

Interventions

PROCEDURE
DEVICE

No Results Yet

NCT07276672 | COMPLETED | PHASE3

80 participants

Efficacy of a Toothpaste Containing Hydrogen Peroxide as Compared to a Regular Fluoride Toothpaste Without Hydrogen Peroxide in the Immediate Removal of Tooth Stains After a Single Brushing.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-11-20
Completion:: 2025-11-24

Conditions

Whitening

Interventions

DRUG

No Results Yet

NCT07276633 | COMPLETED | NA

80 participants

Use of Subanesthetic Dose Propofol Before Extubation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2024-06-01
Completion:: 2024-09-01

Conditions

Emergence Agitation
Rhinoplasty
Patient Satisfaction

Interventions

DRUG
OTHER

No Results Yet

NCT07276620 | NOT_YET_RECRUITING | NA

1000 participants

Treatment of Moderate-to-Severe Atopic Dermatitis With Ivarmacitinib in Adolescents and Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-11-30
Completion:: 2028-04-30

Conditions

Atopic Dermatitis (AD)

Interventions

DRUG

No Results Yet

NCT07276451 | NOT_YET_RECRUITING | NA

82 participants

Effectiveness of the DMHI and OPS Platform in Improving Participant QOL: a Randomised Controlled Trial.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2026-01-01
Completion:: 2026-05-31

Conditions

Anxiety
Depression and Quality of Life
Quality of Life

Interventions

OTHER

No Results Yet

NCT07276412 | RECRUITING | NA

500 participants

Study on the Effect of a Gamified Health Education Programme on Primary School Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2024-09-02
Completion:: 2026-07-24

Conditions

Gamification in Health Education
Health Education

Interventions

BEHAVIORAL

No Results Yet

NCT07276308 | COMPLETED | NA

32 participants

Psychophysiological and Cognitive Responses to Low-Volume High-Intensity Interval Exercise in Overweight-to-Obese Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2023-03-01
Completion:: 2023-08-20

Conditions

Overweight and/or Obesity
Overweight and Obese Adults

Interventions

BEHAVIORAL

No Results Yet

NCT07276269 | ACTIVE_NOT_RECRUITING | NA

80 participants

Survival and Success of CAD/CAM Restorations After 5 Years of Intraoral Use

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2023-11-30
Completion:: 2028-11-30

Conditions

Tooth Wear

Interventions

DEVICE

No Results Yet

NCT07275450 | RECRUITING | NA

128 participants

Comparative Study Between Ultrasound Guided Regional Anesthesia for Awake Tympanoplasty Surgery vs General Anesthesia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-11
Start Date:: 2025-12-10
Completion:: 2026-09-01

Conditions

Ultrasound Guided Nerve Block
Anesthesia , Analgesia

Interventions

PROCEDURE
OTHER

No Results Yet