Clinical Trials Updated in 2025

NCT07253688 | RECRUITING | PHASE3

330 participants

Adjunctive Rifampin for the Treatment of Prosthetic Valve Endocarditis Due to S. Aureus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-11-10
Completion:: 2029-12-31

Conditions

Staphylococcus Aureus Endocarditis
Prosthetic Valve Endocarditis

Interventions

DRUG
OTHER

No Results Yet

NCT07251023 | RECRUITING | PHASE3

450 participants

Efficacy and Safety of DMB-I (INN: Latrepirdine) in Patients With Alzheimer Type Dementia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-11-20
Completion:: 2027-05-31

Conditions

Alzheimer Type Dementia

Interventions

DRUG

No Results Yet

NCT07247162 | NOT_YET_RECRUITING | PHASE4

63 participants

Osilodrostat in Patients With Hypertension Caused by Hypercortisolaemia Due to Cushing's Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2026-08-31
Completion:: 2028-05-31

Conditions

Hypertension
Hypercortisolemia
Cushing Syndrome

Interventions

DRUG

No Results Yet

NCT07242833 | RECRUITING

60 participants

Evaluation of the Effect of Seasonality on Biological Age in Adults

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-11-24
Completion:: 2027-06-30

Conditions

Aging
Aging, Biological
Aging, Healthy
BIOLOGICAL CLOCKS
Biological Clock Disturbance

No Results Yet

NCT07242586 | RECRUITING | NA

20 participants

PS-Trauma - Development of Trauma Treatment for Patients With Co-morbid Psychotic Disorders and Traumas

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-10-02
Completion:: 2026-05-31

Conditions

SCHIZOPHRENIA 1 (Disorder)
Schizotypal Disorder
Post Traumatic Stress Symptoms

Interventions

BEHAVIORAL

No Results Yet

NCT07242222 | RECRUITING | PHASE1/PHASE2

50 participants

Erdosteine in the Treatment of Nonalcoholic Fatty Liver Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-11-20
Completion:: 2026-11-20

Conditions

Fatty Liver

Interventions

OTHER
DRUG

No Results Yet

NCT07236307 | COMPLETED | NA

17 participants

The Feasibility, Efficacy and Safety of UZit®: Single-arm Clinical Trial in Patients With Symptomatic Chronic Venous Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-04-01
Completion:: 2025-08-01

Conditions

Venous Insufficiency of Leg
Drainage
Chronic Venous Disease

Interventions

DEVICE

No Results Yet

NCT07234630 | NOT_YET_RECRUITING

150 participants

Role of Fibrinolytic Activity in Neoplastic Pathologies Complicated by Coagulopathy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2026-01-31
Completion:: 2028-02-29

Conditions

Hematologic Neoplasms
Solid Tumor Metastatic Cancer Advanced Cancer
Disseminated Intravascular Coagulation

Interventions

BIOLOGICAL

No Results Yet

NCT07230366 | NOT_YET_RECRUITING | NA

120 participants

Clinical Validation of AI-powered Smart Vehicle Assisted Gait Training in Neurodegenerative Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2026-01-02
Completion:: 2028-12-10

Conditions

Parkinson's Disease (PD)
Dementia

Interventions

DEVICE

No Results Yet

NCT07229664 | RECRUITING | PHASE2/PHASE3

60 participants

Vinpocetine in Patients With Parkinsonian Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-11-10
Completion:: 2026-11-20

Conditions

Parkinson Disease

Interventions

DRUG

No Results Yet

NCT07216144 | ENROLLING_BY_INVITATION | NA

2000 participants

Centralized Lung Cancer Screening Engagement in At-Risk Populations

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-10-15
Completion:: 2027-02-28

Conditions

Lung Cancer Screening

Interventions

BEHAVIORAL

No Results Yet

NCT07211893 | NOT_YET_RECRUITING | NA

1330 participants

Effect of MyopiaEd Messaging on Improving Eye-use Behavior and Myopia Control Among Primary School Students in China

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-12-05
Completion:: 2026-11-01

Conditions

Myopia

Interventions

OTHER

No Results Yet

NCT07185347 | RECRUITING | PHASE3

70 participants

A Randomized, Parallel-arm, Double Blind, Placebo-controlled Study to Assess the Efficacy of Fampridine for Patients With Spinocerebellar Ataxia SCA27B Caused by a GAA Expansion in the FGF14 Gene

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-10-21
Completion:: 2027-05-21

Conditions

Spinocerebellar Ataxia 27B (SCA27B)

Interventions

DRUG

No Results Yet

NCT07182500 | RECRUITING | PHASE2

75 participants

The Effect of Bifidobacterium Probiotics on Gut Microbiota Changes in Healthy Adults During Short-term Travel Along the Silk Road

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-10-16
Completion:: 2025-12-31

Conditions

Healthy Adult Volunteer

Interventions

OTHER

No Results Yet

NCT07178873 | RECRUITING | NA

35 participants

Psychosocial Teleassistance Programme for Adults With Spina Bifida

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2024-06-25
Completion:: 2027-01-31

Conditions

Spina Bifida
Self Esteem
Quality of Life (QOL)
Self Concept
Anxiety
Depression
Interpersonal Needs

Interventions

BEHAVIORAL

No Results Yet

NCT07176494 | RECRUITING | NA

50 participants

Revision of Deep Brain Stimulator in Patients With Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-09-20
Completion:: 2026-07-05

Conditions

Pain Management
Regional Anesthesia
Deep Brain Stimulation
Parkinsons Disease

Interventions

PROCEDURE

No Results Yet

NCT07172165 | ENROLLING_BY_INVITATION

850 participants

A Multicenter Study to Optimize Microembolic Signal Classification Based on Double--Blind Multiparametric Assessment by Human Experts Using an Universal Graphical Interface [MESOMEGA]

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-05-15
Completion:: 2025-12-15

Conditions

Microemboli
Stroke
Transcranial Doppler Ultrasound

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07170488 | COMPLETED | NA

27 participants

Yoga and Female Concussion

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2023-11-10
Completion:: 2024-04-24

Conditions

Concussion Mild

Interventions

BEHAVIORAL

Results Available

NCT07162662 | RECRUITING | NA

42 participants

A Study on the Modulation of Gut Microbiota by Oral Sialic Acid in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-09-10
Completion:: 2026-08-01

Conditions

Taking Sialic Acid to Regulate the Gut Microbiota
Healthy

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07159126 | RECRUITING | PHASE1

70 participants

A Study of DS3610a in Participants With Advanced Solid Tumor

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-10-09
Completion:: 2028-09-01

Conditions

Solid Tumors
Metastatic Solid Tumors

Interventions

DRUG

No Results Yet

NCT07124585 | NOT_YET_RECRUITING | NA

33 participants

Short-Term Effects of Sucralose and Saccharin on Blood Sugar and Gut Microbiota in Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2026-01-30
Completion:: 2026-09-30

Conditions

Type 2 Diabetes Mellitus (T2DM)

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT07123909 | RECRUITING | NA

60 participants

Studies on Adsorption International Learning Initiative Global

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-06-01
Completion:: 2026-03-31

Conditions

CKD (Chronic Kidney Disease) Stage 5D
Uremia; Chronic
Uremic; Toxemia
Inflammation Chronic
Hemodialysis
Inflammation Biomarkers
Dialysis Related Complication
Anemia Associated With End Stage Renal Disease

Interventions

DEVICE

No Results Yet

NCT07117201 | ENROLLING_BY_INVITATION | NA

30 participants

Promoting Nutrition Security and Chronic Disease Management Through a Produce Prescription Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-09-03
Completion:: 2026-08-31

Conditions

Dietary Intervention
Produce Prescription
Chronic Disease Management
Social Needs Screening

Interventions

BEHAVIORAL

No Results Yet

NCT07116876 | RECRUITING | NA

120 participants

Matrion Decellularized Placental Membrane Versus Conventional Wound Management in Subjects With Diabetic Foot Ulcers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-06-26
Completion:: 2026-05-31

Conditions

Diabetic Foot Ulcer (DFU)
Lower Extremity

Interventions

OTHER

No Results Yet

NCT07111013 | WITHDRAWN | PHASE3

0 participants

A Study to Assess the Long-Term Safety of Lifitegrast/Perfluorohexyloctane Fixed-Dose Combination in Subjects With Dry Eye Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-12-31
Completion:: 2027-04-30

Conditions

Dry Eye Disease

Interventions

DRUG

No Results Yet

NCT07099521 | COMPLETED | NA

74 participants

The Effects of HD-tDCS on Cognitive Bias Among Individuals With Social Anxiety Symptoms

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2024-05-15
Completion:: 2024-11-24

Conditions

Social Anxiety Disorder

Interventions

DEVICE

Results Available

NCT07095075 | RECRUITING | EARLY_PHASE1

36 participants

A Study of LUCAR-DKS1 in Subjects With Relapsed/Refractory Autoimmune Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-10-14
Completion:: 2029-12-31

Conditions

Relapsed/Refractory Autoimmune Diseases

Interventions

BIOLOGICAL

No Results Yet

NCT07093437 | RECRUITING | NA

188 participants

Adhesive Devices Versus Elastic Devices for Urinary Catheter Securement in Critically Ill Patients Experimental Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-09-22
Completion:: 2026-09-30

Conditions

Pressure Injuries
Pain
Catheter-Associated Urinary Tract Infection
Medical Device Site Injury

Interventions

DEVICE

No Results Yet

NCT07085533 | RECRUITING

200 participants

Natural History Study of Inherited Retinal Diseases

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-07-20
Completion:: 2027-06-04

Conditions

Retinal Dystrophies
Color Vision Defects
Vision Disorders
Macular Degeneration
Achromatopsia
Optical Coherence Tomography (OCT)
Visual Acuity
Genotype
Mutation
Phenotype

No Results Yet

NCT07084909 | WITHDRAWN | PHASE2/PHASE3

0 participants

Piflufolastat F 18 PET/CT in Patients With Suspected, or at High Risk for Metastatic ccRCC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-11-30
Completion:: 2027-09-30

Conditions

Clear Cell Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT07083635 | RECRUITING | PHASE2

40 participants

Transdermal Ethinyl Estradiol and Norelgestromin for Irregular Bleeding in Contraceptive Implant Users

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-07-29
Completion:: 2026-09-30

Conditions

Menstruation Disturbances
Metrorrhagia
Uterine Hemorrhage
Contraception Behavior

Interventions

DRUG

No Results Yet

NCT07083219 | ENROLLING_BY_INVITATION | NA

60 participants

Impact of Aerobic Exercise on Pain Modulation in Healthy Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-08-15
Completion:: 2026-07-31

Conditions

Healthy Adult

Interventions

BEHAVIORAL

No Results Yet

NCT07075393 | NOT_YET_RECRUITING

150 participants

Description of Renal Involvement in Wilson's Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2026-02-28
Completion:: 2027-02-28

Conditions

Wilson Disease

Interventions

OTHER

No Results Yet

NCT07075380 | RECRUITING

400 participants

National Survey on Physical and Sports Activity of Adults With Epilepsy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-11-10
Completion:: 2027-05-31

Conditions

Epilepsy

Interventions

BEHAVIORAL

No Results Yet

NCT07071129 | TERMINATED | NA

22 participants

Virtual Reality for Enhancement of Vision

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2018-04-17
Completion:: 2025-07-07

Conditions

Glaucoma
Vision Disorder

Interventions

DEVICE

Results Available

NCT07056036 | COMPLETED | NA

51 participants

EXOMIND (BTL-699-2) for the Improvement in Willpower & Food Cravings

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2024-11-01
Completion:: 2025-10-10

Conditions

Self-Control
Food Cravings

Interventions

DEVICE

No Results Yet

NCT07051746 | COMPLETED | NA

18 participants

Effectiveness of Traditional Chinese Metacognitive Training (MCT) in Patients With Schizophrenia, Depression, or Bipolar Disorder Attending a Psychiatric Day Hospital in Taiwan

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-10-03
Completion:: 2025-11-19

Conditions

Schizophrenia
Major Depressive Disorder
Bipolar Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07050719 | COMPLETED | NA

58 participants

Can Atelectasis Be Prevented With Oxygen Reserve Index (ORI) Monitoring?

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-07-15
Completion:: 2025-12-08

Conditions

Atelectasis
Lung Ultrasonography Score
Hyperoxia

Interventions

PROCEDURE

No Results Yet

NCT07038616 | COMPLETED

158 participants

Observation of the Response to Ovulation Triggering on the Day of Intrauterine Insemination and Correlation Between Progesterone Level and Pregnancy Rate (OVUL-IIU)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-10
Start Date:: 2024-10-01
Completion:: 2024-10-01

Conditions

Infertility

No Results Yet

NCT07035327 | COMPLETED | NA

38 participants

Dual-task Training for Frail Older Adults With Chronic Musculoskeletal Pain (Pilot)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-10
Start Date:: 2025-07-01
Completion:: 2025-10-31

Conditions

Chronic Musculoskeletal Pain
Frailty

Interventions

OTHER

No Results Yet