Clinical Trials Updated in 2025

NCT05555680 | TERMINATED

32 participants

Effect of Hyperandrogenism on IVF Outcomes in PCOS Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-01-21
Completion:: 2025-01-29

Conditions

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Interventions

OTHER

No Results Yet

NCT05555121 | SUSPENDED | PHASE2

150 participants

Rescue Progesterone Supplementation During Frozen Embryo Transfer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-12-01
Completion:: 2028-04-30

Conditions

Fertility Issues
Embryo Implantation
Frozen Embryo Transfer

Interventions

DRUG

No Results Yet

NCT05512754 | RECRUITING | PHASE4

200 participants

Impact of Anti-inflammatory Medications in Patients With Elevated Serum Prostate-specific Antigen

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-08-01
Completion:: 2027-12-31

Conditions

Elevated Serum PSA

Interventions

DRUG

No Results Yet

NCT05500833 | RECRUITING

400 participants

Multidimensional Characterization of Dyspnea in Children

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-01-26
Completion:: 2028-02-26

Conditions

Dyspnea and Respiratory Insufficiency in Children

Interventions

OTHER

No Results Yet

NCT05494593 | WITHDRAWN | PHASE4

0 participants

A Study of ELAPRASE in Treatment-naïve Participants With Hunter Syndrome (Mucopolysaccharidosis [MPS] II)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-02-28
Completion:: 2025-08-29

Conditions

Mucopolysaccharidosis (MPS)
Hunter Syndrome

Interventions

DRUG

No Results Yet

NCT05491213 | RECRUITING | NA

594 participants

TELESCOPE- TELEhealth Shared Decision-making COaching

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-02-14
Completion:: 2026-05-31

Conditions

Lung Neoplasms

Interventions

BEHAVIORAL

No Results Yet

NCT05477147 | COMPLETED | NA

96 participants

Re-Ablation Using a Tailored Approach Targeting EGM-Dispersion

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-03-17
Completion:: 2025-05-07

Conditions

Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT05472142 | COMPLETED | NA

22 participants

Using Practice Facilitation and Operationalizing Referral Information Technology to Increase DSMES Utilization

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-05-30
Completion:: 2024-10-30

Conditions

Diabetes

Interventions

OTHER

Results Available

NCT05446389 | TERMINATED | NA

33 participants

PAL to Improve Oral Feeding for Infants With Chronic Lung Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-06-08
Completion:: 2025-04-24

Conditions

Chronic Lung Disease of Prematurity
Respiratory Distress Syndrome in Premature Infant
Bronchopulmonary Dysplasia
Preterm Birth

Interventions

DEVICE

No Results Yet

NCT05441709 | RECRUITING | NA

990 participants

Furthering Equity Through Infant Feeding EDucation and Support

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-11-08
Completion:: 2026-12-31

Conditions

Breastfeeding

Interventions

BEHAVIORAL

No Results Yet

NCT05391061 | RECRUITING

1100 participants

A Study to Learn About the Study Medicine (Called Cibinqo) in People With Atopic Dermatitis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-01-07
Completion:: 2027-11-22

Conditions

Dermatitis, Atopic

Interventions

DRUG

No Results Yet

NCT05372497 | COMPLETED | NA

48 participants

Central Nervous System Focused Therapy in Frozen Shoulder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-05-11
Completion:: 2022-07-15

Conditions

Frozen Shoulder

Interventions

OTHER

No Results Yet

NCT05356364 | ACTIVE_NOT_RECRUITING | NA

100 participants

Improving Negative Stressful Perseverations in Insomnia to Revitalize Expecting Moms (INSPIRE)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-02-01
Completion:: 2026-04-30

Conditions

Insomnia
Depression

Interventions

BEHAVIORAL

No Results Yet

NCT05345717 | COMPLETED | PHASE1/PHASE2

5 participants

Novel Desensitization Kidney Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-05-01
Completion:: 2025-09-12

Conditions

Kidney Transplantation
End Stage Kidney Disease (ESRD)

Interventions

DRUG

No Results Yet

NCT05338658 | RECRUITING | PHASE1

21 participants

Study of PAT in Patients With Solid Tumor Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-05-19
Completion:: 2027-01-31

Conditions

Metastasis
Solid Tumor

Interventions

DRUG

No Results Yet

NCT05303428 | NOT_YET_RECRUITING | NA

80 participants

Study of Low-intensity Focused Ultrasound Effects on Cognitive fMRI Signals

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2026-10-31
Completion:: 2028-04-30

Conditions

Cognitive Change

Interventions

OTHER

No Results Yet

NCT05289947 | COMPLETED | PHASE2

303 participants

MLC1501 Study Assessing Efficacy in Post STrOke Subjects With mOtor Deficits

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-07-21
Completion:: 2025-07-18

Conditions

Stroke
Stroke, Ischemic
Strokes Thrombotic
Stroke Sequelae
Stroke, Cardiovascular
Stroke, Embolic
Stroke, Cryptogenic

Interventions

OTHER
DRUG

No Results Yet

NCT05280379 | COMPLETED

33 participants

Trained Immunity in Thyroid Carcinoma and Colon Carcinoma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-09-19
Completion:: 2025-05-01

Conditions

Thyroid Cancer, Nonmedullary
Colon Carcinoma

Interventions

OTHER

No Results Yet

NCT05252754 | RECRUITING | PHASE3

4874 participants

Rectal Indomethacin and Oral Tacrolimus Versus Combination to Prevent Post-ERCP Pancreatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-01-18
Completion:: 2026-12-31

Conditions

Post-ERCP Acute Pancreatitis

Interventions

DRUG

No Results Yet

NCT05241210 | SUSPENDED | NA

4150 participants

Real-Time Feedback (RTFB) to Improve Colonoscopy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-12-13
Completion:: 2026-12-31

Conditions

Colorectal Cancer

Interventions

DEVICE

No Results Yet

NCT05203510 | ACTIVE_NOT_RECRUITING | PHASE4

52 participants

A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil Therapy to Reverse Right Ventricular Remodeling in Participants With Pulmonary Arterial Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-10-20
Completion:: 2026-04-30

Conditions

Pulmonary Arterial Hypertension

Interventions

DRUG

No Results Yet

NCT05192603 | ENROLLING_BY_INVITATION | NA

200 participants

Comparison Between Low FODMAP and SSRD in IBS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-03-01
Completion:: 2024-02-13

Conditions

IBS - Irritable Bowel Syndrome

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05131919 | ACTIVE_NOT_RECRUITING | PHASE2

25 participants

Pembrolizumab for Locally Advanced, Irresectable, Non-metastatic dMMR Colorectal Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2022-12-22
Completion:: 2030-07-31

Conditions

Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT05075200 | COMPLETED | PHASE2

21 participants

Tranexamic Acid Dosing for Major Joint Replacement Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-12-14
Completion:: 2022-10-26

Conditions

Arthroplasty, Replacement, Knee
Arthroplasty, Replacement, Hip

Interventions

DRUG

Results Available

NCT05031663 | COMPLETED | NA

61 participants

Effect of Almonds on Immune Strength and Response to Flu Vaccination in Overweight Older Men and Postmenopausal Women: A Randomized Controlled Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-08-12
Completion:: 2023-05-10

Conditions

Immune Response
Inflammation

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05028569 | TERMINATED | PHASE3

775 participants

Study of BOTOX Injections in Prevention of Migraine in Adult Participants With Episodic Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-11-05
Completion:: 2024-11-06

Conditions

Episodic Migraine

Interventions

DRUG

Results Available

NCT05010460 | TERMINATED | PHASE2

98 participants

Study of Roxadustat for Reducing the Incidence of Acute Kidney Injury After Coronary Artery Bypass Grafting

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-09-30
Completion:: 2025-05-20

Conditions

Coronary Artery Bypass

Interventions

DRUG

No Results Yet

NCT04981288 | ACTIVE_NOT_RECRUITING

24 participants

Lipids and Energy Study: Optimizing the Analysis of Lipids and Energy Metabolism in Blood Samples

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-07-02
Completion:: 2025-08-01

Conditions

Healthy

No Results Yet

NCT04908254 | COMPLETED | NA

50 participants

A Multi-center Randomized Control Cross-over Study to Evaluate the Safety and Effectiveness of the Dayspring Active Wearable Compression Device vs. an Advanced Pneumatic Compression Device for Treating Breast Cancer Related Lymphedema

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-06-01
Completion:: 2021-12-31

Conditions

Lymphedema
Lymphedema of Upper Arm
Lymphedema, Breast Cancer

Interventions

DEVICE

No Results Yet

NCT04866576 | COMPLETED | NA

62 participants

Effect of a Fermented Soy Product on Cognition, Immune Status and Vaccine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-08-12
Completion:: 2022-03-01

Conditions

Cognitive Change
Inflammation
Immune Response

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04863664 | COMPLETED | NA

998 participants

Lead EvaluAtion for Defibrillation and Reliability (LEADR) / Lead Evaluation for Defibrillation and Reliability in Left Bundle Branch Area Pacing (LEADR LBBAP)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-06-21
Completion:: 2025-09-03

Conditions

Tachyarrhythmia

Interventions

DEVICE

No Results Yet

NCT04825379 | ACTIVE_NOT_RECRUITING | NA

31 participants

Clinical Evaluation of a Bioactive Material

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-06-01
Completion:: 2021-09-01

Conditions

Tooth Disease

Interventions

DEVICE

No Results Yet

NCT04796792 | RECRUITING | NA

140 participants

Ultrasound to Facilitate Stone Passage

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2023-04-01
Completion:: 2028-05-31

Conditions

Urinary Stone
Urinary Calculi

Interventions

DEVICE

No Results Yet

NCT04784416 | ACTIVE_NOT_RECRUITING | PHASE2

196 participants

Transcranial Photobiomodulation for Alzheimer's Disease (TRAP-AD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-04-27
Completion:: 2025-10-30

Conditions

Mild Cognitive Impairment
Alzheimer Disease

Interventions

DEVICE
DRUG

No Results Yet

NCT04745728 | RECRUITING | PHASE3

200 participants

Different Immunosuppressive Treatment in iMN

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-04-14
Completion:: 2027-12-31

Conditions

Idiopathic Membranous Nephropathy

Interventions

DRUG

No Results Yet

NCT04743739 | TERMINATED | PHASE3

12 participants

Rituximab Combined With Cyclosporine Versus Rituximab Alone in the Treatment of iMN

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-04-14
Completion:: 2022-12-20

Conditions

Idiopathic Membranous Nephropathy

Interventions

DRUG

No Results Yet

NCT04738422 | ENROLLING_BY_INVITATION | PHASE2

150 participants

Determining Airway pH by Compartmental Exhaled Nitric Oxide Levels During Alkaline Buffer Challenge

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2020-09-11
Completion:: 2028-07-15

Conditions

Airway Disease

Interventions

DRUG

No Results Yet

NCT04735367 | COMPLETED

42 participants

Study to Evaluate Overall Survival in Japanese Patients With HR+/HER2- Advanced Breast Cancer Treated With Palbociclib Plus Letrozole

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-02-03
Completion:: 2023-09-29

Conditions

Breast Cancer

Interventions

DRUG

Results Available

NCT04707469 | COMPLETED | PHASE3

1606 participants

Research Study to Compare Three Doses of Semaglutide Tablets Taken Once Daily in People With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2021-01-15
Completion:: 2023-03-07

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

Results Available

NCT04677946 | NOT_YET_RECRUITING | NA

16 participants

Dietary Oil to Improve Sleep Quality

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-09
Start Date:: 2027-12-31
Completion:: 2028-12-31

Conditions

Insomnia Type; Sleep Disorder

Interventions

OTHER

No Results Yet