Clinical Trials Updated in 2025

NCT07269886 | COMPLETED

79 participants

BIOMARKERS FOR DRUG SELECTION IN DEPRESSION

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-08-18
Completion:: 2022-10-16

Conditions

Depression - Major Depressive Disorder

No Results Yet

NCT07269860 | COMPLETED | NA

27 participants

Impact of Osteopathic Manipulative Medicine on Sentinal Lymph Node Biopsy Dye and Tracer Uptake

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-07-09
Completion:: 2025-10-30

Conditions

Breast Cancer

Interventions

PROCEDURE

No Results Yet

NCT07269691 | NOT_YET_RECRUITING | PHASE3

194 participants

RaSOLVE: 125I Radioactive Seed Marking Effects on Pathological Complete Response Rate and Prognosis Post-Neoadjuvant Therapy in Early/Advanced Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-12-01
Completion:: 2027-12-01

Conditions

Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Breast Cancer

Interventions

DEVICE
DRUG

No Results Yet

NCT07269639 | NOT_YET_RECRUITING | PHASE1/PHASE2

20 participants

Golcadomide, Poseltinib, and Rituximab for Relapsed/Refractory Diffuse Large B-cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2026-01-01
Completion:: 2027-12-01

Conditions

Large B-Cell Lymphoma (LBCL)

Interventions

DRUG

No Results Yet

NCT07269626 | RECRUITING | PHASE2

47 participants

PULSAR in Systemic Therapy for Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-11-14
Completion:: 2027-12-31

Conditions

Locally Advanced Pancreatic Ductal Adenocarcinoma
Borderline Resectable Pancreatic Ductal Adenocarcinoma
Oligometastatic Pancreatic Ductal Adenocarcinoma

Interventions

RADIATION

No Results Yet

NCT07269574 | NOT_YET_RECRUITING

600 participants

Impact of Dietary Patterns on Prognosis of Ovarian Cancer Patients During PARPi Maintenance

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-11-27
Completion:: 2026-11-30

Conditions

Ovarian Cancer
Fallopian Tube Cancers
Primary Peritoneal Carcinoma
High-grade Serous Ovarian Cancer

No Results Yet

NCT07269561 | RECRUITING

50000 participants

Headache Registration and Followup Initiated by Tongji Hospital, HUST

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2024-01-01
Completion:: 2028-12-31

Conditions

Headache
Comorbidities

No Results Yet

NCT07269548 | RECRUITING

30 participants

Evaluation of the Healing of the Pilonidal Cyst After 1940 nm Laser Treatment

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-10-03
Completion:: 2026-06-30

Conditions

Pilonidal Cyst/Fistula

Interventions

PROCEDURE

No Results Yet

NCT07269535 | NOT_YET_RECRUITING

500 participants

A Prospective Validation Study of Radiomics in the Differential Diagnosis of Uterine Leiomyoma and Uterine Sarcoma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-11-30
Completion:: 2050-01-01

Conditions

Uterine Fibroid
Uterine Sarcoma
AI (Artificial Intelligence)
Radiomic
Prospective Observational Study
MRI

Interventions

OTHER

No Results Yet

NCT07269522 | COMPLETED | NA

60 participants

Arthroscopic Anterior Cruciate Ligament Reconstruction by Hamstring Graft With and Without Platelet-Rich Plasma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-01-15
Completion:: 2023-06-30

Conditions

Anterior Cruciate Ligament Injury

Interventions

PROCEDURE

No Results Yet

NCT07269509 | NOT_YET_RECRUITING | NA

276 participants

Evaluation of the Efficacy and Safety of an Intensified Strategy of Intratonsillar Immunotherapy (ITIT) for Allergic Rhinitis: A Multicenter, Randomized, Double-blind, Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-12-30
Completion:: 2028-12-31

Conditions

Allergic Rhinitis

Interventions

PROCEDURE

No Results Yet

NCT07269431 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:: 2025-12-08

No Results Yet

NCT07269418 | ACTIVE_NOT_RECRUITING

36 participants

Optimization of Conoid Anatomical Reconstruction During Ligamentoplasty for Acromioclavicular Disjunction

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2024-03-28
Completion:: 2028-03-31

Conditions

Acromioclavicular; Dislocation
Ligament Repair or Reconstruction

No Results Yet

NCT07269379 | RECRUITING | NA

108 participants

Intradialytic Exercise With Blood Flow Restriction in Hemodialysis Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-11-06
Completion:: 2028-05-06

Conditions

Dialysis Patients

Interventions

OTHER

No Results Yet

NCT07269314 | RECRUITING

200 participants

Introduction of Polymerase Chain Reaction (PCR) in Microbiology and Parasitology

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2023-09-01
Completion:: 2026-09-01

Conditions

Malaria, Pneumocystis, Leishmania

No Results Yet

NCT07269288 | NOT_YET_RECRUITING

1500 participants

The Correlation and Mechanistic Study of GGCX Gene With Prognosis in Acute Ischemic Stroke

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2026-01-25
Completion:: 2026-08-31

Conditions

Acute Ischemic Stroke

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT07269249 | RECRUITING

50 participants

Real-world Efficacy and Safety of Neoadjuvant Dostarlimab in Patients With dMMR/MSI-H Locally Advanced Rectal Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-09-01
Completion:: 2027-01-31

Conditions

Locally Advanced Rectal Cancer (LARC)

Interventions

DRUG

No Results Yet

NCT07269236 | ENROLLING_BY_INVITATION

2000 participants

Prospective Real-World Study of Multimodal AI

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-10-01
Completion:: 2030-09-30

Conditions

Pancancer

No Results Yet

NCT07269197 | COMPLETED

67 participants

Association of SGLT2 Inhibitors Therapy With Elastographic and Molecular Markers of Liver Injury in Type 2 Diabetes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2024-03-22
Completion:: 2025-10-10

Conditions

Non-Alcoholic Fatty Liver Disease
Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT07269184 | NOT_YET_RECRUITING | NA

60 participants

Impact of Ultrasound Guidance on Central Neuraxial Block Success in Patients With Non-Palpable Vertebral Anatomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-12-01
Completion:: 2026-03-01

Conditions

Epidural Analgesia
Ultrasound Assistance

Interventions

PROCEDURE

No Results Yet

NCT07269171 | NOT_YET_RECRUITING | NA

15 participants

The Effect of Supplementary Foods Containing Trypsin, Chymotrypsin and Serratia Peptidase on Healing After Impacted Wisdom Tooth Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-12-01
Completion:: 2026-02-28

Conditions

Oral Health Care

Interventions

PROCEDURE

No Results Yet

NCT07269158 | NOT_YET_RECRUITING | PHASE1/PHASE2

160 participants

A Phase IIb Randomized Clinical Trial of Immune Checkpoint Inhibitor-based Maintenance Therapy in Patients With Advanced Biliary Tract Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-12-31
Completion:: 2029-09-30

Conditions

Biliary Tract Neoplasms
Advanced Cancer
Immunotherapy

Interventions

DRUG

No Results Yet

NCT07269132 | ENROLLING_BY_INVITATION | NA

50 participants

Applying the ADDIE Model to Develop a Multimedia Program to Enhance Chemotherapy Knowledge and Self-Efficacy Among Intensive Care Unit Nurses

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-11-01
Completion:: 2026-07-30

Conditions

Nurse
Self-Efficacy
eLearning
Chemotherapy
ICU

Interventions

OTHER

No Results Yet

NCT07269067 | NOT_YET_RECRUITING

60 participants

Automated vs Manual Flow-cytometry Gating for Measurable Residual Disease in Acute Myeloid Leukaemia (DUALFLOW)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2026-01-31
Completion:: 2027-07-31

Conditions

Leukemia, Myeloid, Acute

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07269028 | COMPLETED | NA

248 participants

Personalised and Gamification-based Decision Aid (DA): a Randomized Controlled Pilot Study About Colorectal Cancer (CRC) Screening

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2023-05-15
Completion:: 2024-12-31

Conditions

Colo-rectal Cancer

Interventions

OTHER

No Results Yet

NCT07269015 | NOT_YET_RECRUITING | NA

66 participants

CGM Accuracy in Pregnancy Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-12-31
Completion:: 2026-12-31

Conditions

Pregestational Diabetes
Continuous Glucose Monitoring

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT07269002 | COMPLETED | NA

3600 participants

Clinical Pharmacist Impact Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-03-15
Completion:: 2025-09-15

Conditions

Medication Safety
Preventable Medication Harm
Pharmacotherapy Optimization

Interventions

OTHER

No Results Yet

NCT07268976 | COMPLETED | NA

30 participants

Jackfruit Effects on Adipokines and Cognition in Boxers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-01-07
Completion:: 2025-02-10

Conditions

Exercise Physiology
Cognitive Function
Adipokine Response
Brain-Derived Neurotrophic Factor (BDNF)
Irisin
Omentin-1

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07268963 | ACTIVE_NOT_RECRUITING

60 participants

Biofeedback for Dysfunctional Voiding and Giggle Incontinence

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2022-09-01
Completion:: 2025-12-31

Conditions

Biofeedback Therapy
Dysfunctional Voiding
Giggle Incontinence

Interventions

BEHAVIORAL

No Results Yet

NCT07268937 | COMPLETED

25 participants

Assessment of Hepatic Steatosis Using Dedicated Software Implemented on Ultrasound Devices

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2023-07-06
Completion:: 2025-05-05

Conditions

Non-alcoholic Fatty Liver Disease (NAFLD)

Interventions

DEVICE

No Results Yet

NCT07268924 | NOT_YET_RECRUITING | PHASE4

82 participants

The Effect of Propofol Versus Lidocaine on Emergence Agitation in Children Undergoing Tonsillectomy.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2026-01-31
Completion:: 2027-12-31

Conditions

Emergence Delirium, Anesthesia

Interventions

DRUG

No Results Yet

NCT07268898 | NOT_YET_RECRUITING

500 participants

National Multicenter Retrospective Real-World Study on the Treatment Status of Newly Diagnosed and Persistent Primary Immune Thrombocytopenia (ITP) Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-11-25
Completion:: 2026-02-25

Conditions

Immune Thrombocytopenia (ITP)

No Results Yet

NCT07268885 | COMPLETED | PHASE2

35 participants

PRP Spinoplasty for Chronic Low Back Pain With Multiple Pathologies: A Quasi-Experimental Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2024-09-15
Completion:: 2025-03-01

Conditions

Lower Back Pain Chronic
Lumbar Disc Disease
Facet Joint Arthritis

Interventions

BIOLOGICAL

No Results Yet

NCT07268859 | RECRUITING | NA

110 participants

Effect of Fan Application in Preventing Ticagrelor-Associated Dyspnea

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-03-15
Completion:: 2026-01-10

Conditions

Acute Coronary Syndromes
Ticagrelor
Dyspnea

Interventions

OTHER

No Results Yet

NCT07268846 | RECRUITING | NA

164 participants

Use of Preoperative Postbiotic Supplementation in Colorectal Cancer Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-06-01
Completion:: 2027-06-01

Conditions

Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT07268833 | RECRUITING

400 participants

Translating Single-cell Vulnerability Into Novel ALS Biomarkers and Therapeutic Targets: Towards a Liquid Nerve Biopsy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2024-10-24
Completion:: 2027-04-30

Conditions

Amyotrophic Lateral Sclerosis (ALS)
Peripheral Neuropathies

No Results Yet

NCT07268807 | NOT_YET_RECRUITING

200 participants

Effect of Roxadustat on Heart Failure Patients With Anaemia and Moderate-to-Severe Chronic Kidney Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-12-01
Completion:: 2026-09-01

Conditions

Heart Failure
CKD
Anemia

Interventions

DRUG

No Results Yet

NCT07268794 | NOT_YET_RECRUITING | PHASE2

112 participants

CONVERT-HB1: Radical Prostatectomy After Systemic Therapy for High-volume Metastatic Hormone-sensitive Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-11-30
Completion:: 2027-04-30

Conditions

Metastatic Prostate Cancer
Prostate Cancer (Adenocarcinoma)
Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

Interventions

DRUG
PROCEDURE
RADIATION

No Results Yet

NCT07268781 | ACTIVE_NOT_RECRUITING | NA

102 participants

Impact of Golden Rice-Piper Crocatum Cookies on Lipid Control in Diabetes Mellitus Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-10-20
Completion:: 2025-11-30

Conditions

Diabetes Mellitus (DM)
Dyslipidemia
Lipid Profile
Functional Food
Nutritional Intervention
Cardiovascular Risk Factor

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07268768 | RECRUITING

64 participants

PERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENSITIZATION IN HEADACHE

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-08
Start Date:: 2025-11-20
Completion:: 2028-11-20

Conditions

Chronic and Episodic Headache
Headache Disorders

Interventions

OTHER

No Results Yet