Clinical Trials Updated in 2025

NCT06982365 | COMPLETED | NA

80 participants

Study to Investigate the Potential Health Benefits of Grapes Seeds Extract Supplementation in the Management of Elevated Blood Pressure or Stage 1 Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-08-01
Completion:: 2025-11-07

Conditions

Elevated Blood Pressure
Hypertension

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT06969937 | RECRUITING | PHASE2

75 participants

Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in Alcohol Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-06-01
Completion:: 2026-12-31

Conditions

Alcohol Abuse/Dependence
Alcohol Use Disorder (AUD)
Alcoholism

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT06965192 | RECRUITING | NA

220 participants

Designing Visual Tools to Enhance Cancer Surgeon Decision-making

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-04-24
Completion:: 2027-06-30

Conditions

Prostate Cancer
Kidney Cancer

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06936553 | COMPLETED

51 participants

Comparison of IL-8, FGF-1 and VEGF Levels in Pulpal Tissue, GCF and Dentinal Fluid Samples of Healthy, Reversible and Irreversible Pulpitis Diagnosed Teeth

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-03-03
Completion:: 2025-09-03

Conditions

Pulpitis
Pulp Inflammation
Healthy Pulp
Biomarkers
Reversible Pulpitis

No Results Yet

NCT06925750 | ACTIVE_NOT_RECRUITING | PHASE2

130 participants

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-031/LIGHTRAY EXTENSION)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-05-12
Completion:: 2028-06-16

Conditions

Pulmonary Arterial Hypertension

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06920693 | ACTIVE_NOT_RECRUITING | PHASE1

40 participants

Study to Investigate the Safety, Tolerability, and Pharmacokinetics of GB-7624 in Healthy Adult Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-03-27
Completion:: 2026-08-30

Conditions

Atopic Dermatitis (AD)

Interventions

DRUG

No Results Yet

NCT06915155 | ACTIVE_NOT_RECRUITING

300 participants

Swing-Mesh™ Study (SMS).

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-04-07
Completion:: 2025-08-30

Conditions

Inguinal Hernia

Interventions

DEVICE

No Results Yet

NCT06897163 | COMPLETED | NA

10 participants

A New Method for Ileostomy Output Collection Using an Intestinal Tampon

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-12-10
Completion:: 2025-07-31

Conditions

Ileostomy - Stoma

Interventions

DEVICE

No Results Yet

NCT06877156 | COMPLETED

9 participants

Local Potential Measurement In PFA: A Pilot Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-07-28
Completion:: 2025-07-30

Conditions

Atrial Fibrillation (AF)

No Results Yet

NCT06868264 | ACTIVE_NOT_RECRUITING | PHASE3

880 participants

C-BEYOND: Efficacy and Safety of BEM/RZR vs. SOF/VEL in Subjects With Chronic HCV

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-04-07
Completion:: 2026-09-30

Conditions

HEPATITIS C VIRUS CHRONIC INFECTION

Interventions

DRUG

No Results Yet

NCT06866158 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

80 participants

Autologous Dendritic Cell as Adjunct Therapy for Diabetic Kidney Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-05-01
Completion:: 2024-08-05

Conditions

Diabetic Kidney Disease (DKD)

Interventions

BIOLOGICAL

No Results Yet

NCT06862986 | COMPLETED | NA

40 participants

Ear Massage Effect on Bowel Activity After Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-09-10
Completion:: 2025-12-01

Conditions

Constipation
Lower Extremity Surgery

Interventions

OTHER

No Results Yet

NCT06862154 | COMPLETED | PHASE4

104 participants

Comparison of the Efficiency of Femur Nerve Block and Intravenous Analgesia Treatment in Hip Fracture Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2022-11-01
Completion:: 2024-12-01

Conditions

Hip Fractures
Analgesia
Femoral Nerve

Interventions

DRUG
PROCEDURE

Results Available

NCT06853405 | RECRUITING | NA

120 participants

Nutrition-based Interventions to Prevent Cognitive Decline

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-01-27
Completion:: 2026-05-31

Conditions

Cognitive Dysfunction
Cognition Disorder
Memory Disorders
Cognitive Impairment
Neurocognitive Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06850233 | COMPLETED

100 participants

The Validation of a CAD Screening Algorithm Based on Facial Photos in Community Population

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-03-04
Completion:: 2025-06-24

Conditions

Coronary Artery Disease

Interventions

OTHER

No Results Yet

NCT06817525 | RECRUITING | PHASE2

64 participants

Nab-P+Cb+PD1 Inhibitors as Neoadjuvant Therapy for Early TNBC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-11-06
Completion:: 2026-05-31

Conditions

Triple-negative Breast Cancer

Interventions

DRUG

No Results Yet

NCT06798636 | RECRUITING | EARLY_PHASE1

30 participants

PsiloIMAGINE: A Psychedelic-augmented Mental Imagery-based Intervention for Young People With Self-harm

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-10-01
Completion:: 2026-08-31

Conditions

Self Harm

Interventions

DRUG

No Results Yet

NCT06798129 | ACTIVE_NOT_RECRUITING

5269 participants

Effects of Extracorporeal Treatment in Patients With Acute Poisoning

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2015-01-01
Completion:: 2023-12-31

Conditions

Poisoning
Extracorporeal Treatment

Interventions

PROCEDURE

No Results Yet

NCT06797869 | ACTIVE_NOT_RECRUITING | PHASE2

142 participants

A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-01-29
Completion:: 2026-08-21

Conditions

Diabetes Mellitus, Type 2
Diabetic Peripheral Neuropathy

Interventions

DRUG

No Results Yet

NCT06787131 | COMPLETED | PHASE1

104 participants

Clinical Study Aiming to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a Single Administration of ZE50-0134 at 5 Dose Levels in Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-05-21
Completion:: 2025-07-04

Conditions

Healthy

Interventions

DRUG

No Results Yet

NCT06758700 | RECRUITING | PHASE2

15 participants

Post-line Treatment With Teniposide for c-Myc-driven Extensive-stage Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-02-07
Completion:: 2026-06-30

Conditions

Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Thoracic Neoplasms
Lung Neoplasms
Lung Diseases

Interventions

DRUG

No Results Yet

NCT06736366 | COMPLETED | NA

25 participants

Study With Two Coenzyme Q10 Products

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-12-05
Completion:: 2024-12-16

Conditions

Coenzyme Q Deficiency

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06735144 | RECRUITING | PHASE1/PHASE2

200 participants

Phase I/II Clinical Study of FH-006 for Injection in Patients With Malignant Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-12-23
Completion:: 2027-12-31

Conditions

Malignant Solid Tumor

Interventions

DRUG

No Results Yet

NCT06734260 | RECRUITING | PHASE3

477 participants

Optimization of Keverprazan-amoxicillin Dual Therapy for Eradicating Helicobacter Pylori Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-09-10
Completion:: 2025-11-10

Conditions

Helicobacter Pylori Eradication Rate

Interventions

DRUG

No Results Yet

NCT06731894 | RECRUITING | PHASE2

120 participants

Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-10-03
Completion:: 2028-01-07

Conditions

Breast Carcinoma
Chemotherapy-Induced Peripheral Neuropathy
Colon Carcinoma

Interventions

PROCEDURE
DRUG
OTHER

No Results Yet

NCT06727318 | COMPLETED

192 participants

Comparison of Peripheral Perfusion Indicators and Lactate Levels

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-05-01
Completion:: 2025-08-18

Conditions

Sepsis
Shock, Septic
Hypotensive
Lactate
Lactic Acidosis

No Results Yet

NCT06707987 | COMPLETED

23250 participants

Post-registration Trial of the Non-immunogenic Staphylokinase in Acute Ischemic Stroke (FORPI Registry)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2021-03-01
Completion:: 2024-12-31

Conditions

Acute Ischemic Stroke

Interventions

DRUG

No Results Yet

NCT06689111 | RECRUITING | NA

100 participants

Correlation of Typical LBBB Mechanical Activation Pattern by 2D Strain Echocardiography With Acute GWE Improvement in Patients Receiving LBBp or Conventional BiVp for Cardiac Resynchronization Therapy (Echo LBBp)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-05-23
Completion:: 2026-09-30

Conditions

Heart Failure With Reduced Ejection Fraction (HFrEF)

Interventions

DEVICE

No Results Yet

NCT06676527 | RECRUITING

39 participants

Vorolanib in the Second-line Treatment of Patients With Unresectable or Metastatic Renal Cell Carcinoma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-09-01
Completion:: 2026-09-01

Conditions

Neoplasms
Kidney Neoplasms
Urologic Neoplasms
Urogenital Neoplasms
Female Urogenital Diseases
Male Urogenital Diseases
Urogenital Diseases
Kidney Diseases
Urologic Diseases
Carcinoma
Renal Cell Cancer
Carcinoma, Renal Cell
Antineoplastic Agents

Interventions

OTHER

No Results Yet

NCT06664801 | COMPLETED | PHASE2

164 participants

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (PAH) (MK-7962-024)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-11-14
Completion:: 2025-11-20

Conditions

Pulmonary Arterial Hypertension

Interventions

BIOLOGICAL

No Results Yet

NCT06649227 | RECRUITING | PHASE1

5 participants

Study Investigating the Safety of CD19 CAR-T Cells in Relapsed/Refractory AML Expressing CD19

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-07-10
Completion:: 2029-07-10

Conditions

Relapsed Adult AML

Interventions

DRUG

No Results Yet

NCT06646003 | COMPLETED

341 participants

Reference Values and Determinants of 6-minute Walk Test

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-11-30
Completion:: 2025-11-25

Conditions

Stroke

Interventions

OTHER

No Results Yet

NCT06643520 | COMPLETED | NA

82 participants

19G FNB Needle vs 22G FNB Needle for EUS-Guided Liver Biopsy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-07-01
Completion:: 2025-03-01

Conditions

Endoscopic Ultrasonography
Liver Biopsy

Interventions

DEVICE

No Results Yet

NCT06642675 | RECRUITING | NA

40 participants

nTMS for Negative Symptom in Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-11-22
Completion:: 2026-02-28

Conditions

Schizophrenia

Interventions

DEVICE

No Results Yet

NCT06635551 | RECRUITING | NA

100 participants

Comparison of Vascular Catheter-Related Thrombosis and Risk Factors After Oncologic and Non-Oncologic Major Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-12-04
Completion:: 2026-02-28

Conditions

Catheter Related Complication
Thromboses, Venous
Surgery

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06622629 | COMPLETED | NA

100 participants

Nature Based Therapy With Mindful Walks in Urban Coastal Setting - Barcelona (Spain)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-09-02
Completion:: 2025-07-30

Conditions

Healthy Participants

Interventions

OTHER

No Results Yet

NCT06619275 | COMPLETED

10 participants

Ripretinib (QINLOCK®) According to Current SmPC

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-10-17
Completion:: 2025-08-15

Conditions

GIST - Gastrointestinal Stromal Tumor

Interventions

DRUG

No Results Yet

NCT06618807 | RECRUITING | NA

60 participants

Infrared Light for Memory Loss in Mild Cognitive Impairment (MCI)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-01-10
Completion:: 2027-08-01

Conditions

Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease

Interventions

DEVICE

No Results Yet

NCT06612203 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

76 participants

Clinical Study to Evaluate Debio0123 + Sacituzumab Govitecan Combination in TNBC or HR+/HER2- Advanced Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2025-01-17
Completion:: 2027-02-28

Conditions

Advanced Breast Cancer

Interventions

DRUG

No Results Yet

NCT06610760 | RECRUITING | PHASE4

196 participants

Efficacy and Safety of Ursodeoxycholic Acid in Reversing Gastric Intestinal Metaplasia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-05
Start Date:: 2024-11-12
Completion:: 2026-10-31

Conditions

Gastric Intestinal Metaplasia

Interventions

DRUG

No Results Yet