Clinical Trials Updated in 2025

NCT07263425 | RECRUITING | PHASE2

26 participants

Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Trastuzumab in Breast Cancer With Leptomeningeal Metastasis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-10-27
Completion:: 2027-10-27

Conditions

Leptomeningeal Metastasis of HER2-positive Breast Cancer

Interventions

DRUG

No Results Yet

NCT07263412 | RECRUITING

1000 participants

Gestational Lifestyle & Outcomes Wellness

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-02-25
Completion:: 2026-11-30

Conditions

GDM

Interventions

DEVICE
BEHAVIORAL
OTHER

No Results Yet

NCT07263399 | NOT_YET_RECRUITING | NA

32 participants

Effect of Hydrogen Gas on Hyperbaric Oxygen Toxicity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2026-01-31
Completion:: 2029-12-31

Conditions

Oxygen Toxicity
Oxidative Stress
Hyperoxia
Hyperbaric Oxygen
Healthy Subjects (HS)
Diving Medicine
Hydrogen-oxygen Gas

Interventions

OTHER

No Results Yet

NCT07263386 | RECRUITING | PHASE2

460 participants

A Phase II, Multicenter, Randomized, Controlled Clinical Study Comparing the Efficacy and Safety of Sintilimab Plus SOX Versus SOX Alone as Adjuvant Therapy for PD-L1-Positive, Stage pN3 Gastric Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-10-23
Completion:: 2028-10-31

Conditions

Gastric Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT07263373 | COMPLETED

2000 participants

Multicenter Cohort Study on Predicting Bronchiectasis Progression, Complications, and Prognosis Using Multi-omics

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-04
Start Date:: 2020-01-01
Completion:: 2025-06-30

Conditions

Bronchiectasis Adult
Radiomics

No Results Yet

NCT07263360 | NOT_YET_RECRUITING | PHASE2

29 participants

Iparomlimab and Tuvonralimab Injection Combined With GemOX and Lenvatinib as Conversion Therapy for Initially Potentially Resectable Intrahepatic Cholangiocarcinoma and Gallbladder Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2026-02-01
Completion:: 2028-03-31

Conditions

BTC

Interventions

DRUG

No Results Yet

NCT07263334 | COMPLETED | NA

25 participants

Does Mental Fatigue Caused by Social Media Use Affect Biomechanical Properties of Muscles in Young Male Athletes?

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2024-06-01
Completion:: 2024-12-20

Conditions

Mental Fatigue
Socail Media Usage
Cervical Range of Motion

Interventions

OTHER

No Results Yet

NCT07263269 | ACTIVE_NOT_RECRUITING | NA

200 participants

Comparing Dumping Symptoms and Quality of Life 6 Months After Sleeve Gastrectomy With or Without Transit Bipartition in Adults With Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2024-04-06
Completion:: 2025-06-30

Conditions

Obesity
Morbid Obesity
Dumping Syndrome
Postgastrectomy Syndrome
Quality of Life
Bariatric Surgery
Metabolic Diseases
Gastrointestinal Function Disorders
Sleeve Gastrectomy
Gastrointestinal Transit
Nutritional Status
Patient-reported Outcome Measures

Interventions

PROCEDURE

No Results Yet

NCT07263217 | RECRUITING | NA

30 participants

Mechanistic Study on the Protective and Regenerative Effects of Spirulina in Hepatectomy-Related Liver Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-10-01
Completion:: 2028-09-30

Conditions

Cholangiocarcinoma

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07263204 | RECRUITING

15000 participants

AI-Enabled Diagnosis and Prognosis of Hypertrophic Cardiomyopathy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-01-01
Completion:: 2026-06-01

Conditions

Hypertrophic Cardiomyopathy (HCM)
Left Ventricular Hypertrophy

No Results Yet

NCT07263191 | RECRUITING

3000 participants

A Study of Olanzapine in Participants With Bipolar Disorder.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-10-30
Completion:: 2027-09-30

Conditions

Bipolar Disorder

Interventions

DRUG

No Results Yet

NCT07263178 | RECRUITING

1000 participants

A Study of Second- and Later-line Palliative Chemotherapy in Patients With Metastatic Colorectal Cancer.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-11-07
Completion:: 2029-12-31

Conditions

Metastatic Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT07263165 | NOT_YET_RECRUITING | NA

54 participants

Dexmedetomidine as an Adjuvant to Bupivacaine for Ultrasound-Guided External Oblique Intercostal Block

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-12-15
Completion:: 2026-02-15

Conditions

Opioid Consumption, Postoperative

Interventions

DRUG

No Results Yet

NCT07263100 | COMPLETED | NA

20 participants

Comparative Study Between Intralesional Corticosteroid Injection Alone and Combined Intralesional Corticosteroid Injection With Either Long-pluse Nd YAG or Erbium Yag for Treating Hypertrophic or Keloid Scars

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2023-05-01
Completion:: 2024-01-31

Conditions

Hypertrophic Scar
Keloid
Laser

Interventions

DRUG
DEVICE

No Results Yet

NCT07263009 | NOT_YET_RECRUITING

100 participants

Reflux Flow Volume Impact on Semen Parameters Pre and Post Varicocelectomy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-12-31
Completion:: 2026-11-30

Conditions

Varicocele

No Results Yet

NCT07262996 | COMPLETED

70 participants

Comparison the Gender Effects of Knee Joint and Foot Complex Alignment During Single Leg Squat in Sedentaries

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-04
Start Date:: 2023-09-25
Completion:: 2024-07-25

Conditions

Woman's Role
Men's Role

Interventions

BEHAVIORAL

No Results Yet

NCT07262970 | AVAILABLE

Intermediate-Size Cohort EAP for Ersodetug in Patients With Inadequately Controlled Hypoglycemia Related to a Tumor

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-12-04

Conditions

Tumor-associated Hyperinsulinism (Tumor HI)

Interventions

DRUG

No Results Yet

NCT07262944 | RECRUITING | NA

60 participants

EOI Block in Otoplasty With Rib Cartilage Graft

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2026-12-01
Completion:: 2028-06-01

Conditions

Postoperative Pain, Acute

Interventions

PROCEDURE

No Results Yet

NCT07262931 | NOT_YET_RECRUITING | NA

52 participants

Effect Of Sensory Motor Training Versus Resistance Training Among Individuals With Knee Osteoarthritis.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-12-01
Completion:: 2026-06-01

Conditions

Knee Osteoarthristis

Interventions

OTHER

No Results Yet

NCT07262918 | NOT_YET_RECRUITING | NA

48 participants

The Impact of Medical TV Drama in Improving Literacy on Asthma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-12-25
Completion:: 2026-03-25

Conditions

Asthma

Interventions

DEVICE

No Results Yet

NCT07262905 | COMPLETED

100 participants

Risk Indicators and IPI Performance in Sedation-Related Respiratory Deterioration in COPD

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-01-20
Completion:: 2025-04-20

Conditions

COPD (Chronic Obstructive Pulmonary Disease)
Endoscopy, Gastrointestinal

Interventions

OTHER

No Results Yet

NCT07262892 | RECRUITING | NA

60 participants

3D Evaluation of Maxillary Expansion Methods

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-11-20
Completion:: 2026-06-30

Conditions

Maxillary Transverse Deficiency

Interventions

DEVICE

No Results Yet

NCT07262879 | COMPLETED | NA

60 participants

Stretching Exercises for Dialysis Patients to Reduce Muscle Cramps

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2024-09-01
Completion:: 2024-12-15

Conditions

Muscle Cramp
Renal Dialysis
Exercise Therapy
Nursing Care

Interventions

OTHER

No Results Yet

NCT07262866 | ACTIVE_NOT_RECRUITING | NA

128 participants

Evaluation of the Effects of Education and Counseling Provided to Patients Via Distance Nursing After Cataract Surgery on Regular Use of Medications and Patient Satisfaction. CAT-TELEMED (Cataract - Telemedicine) TNCat-25 (Tele-Nursing Cataract - 2025)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-01-16
Completion:: 2025-06-11

Conditions

Cataract Patients
Cataract After Surgery
Cataract Surgery

Interventions

BEHAVIORAL

No Results Yet

NCT07262853 | RECRUITING | NA

288 participants

Dual Executive Function Training Package

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-10-13
Completion:: 2026-06-30

Conditions

ADHD
Dyslexia
Autism

Interventions

OTHER

No Results Yet

NCT07262840 | RECRUITING | NA

80 participants

Health Behavior Change in High-Risk Colorectal Cancer Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-11-10
Completion:: 2026-02-10

Conditions

Health Behavior
Colorectal Neoplasms
Primary Prevention/Methods

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT07262801 | RECRUITING | NA

50 participants

Psychological and Physiological Impact of a Mindfulness-based Intervention on Anxiety Disorders During the Postpartum Period

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-12-31
Completion:: 2026-09-30

Conditions

Postpartum Anxiety
Anxiety Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT07262749 | NOT_YET_RECRUITING | NA

124 participants

Intraperitoneal Gas Drainage to Reduce Postoperative Shoulder Pain After Gynecologic Laparoscopy .

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-12-01
Completion:: 2026-12-01

Conditions

Postoperative Shoulder Pain After Gynecologic Laparoscopy

Interventions

OTHER

No Results Yet

NCT07262736 | COMPLETED | PHASE1

33 participants

Pharmacokinetics of Clozapine and Norclozapine and the Effect of Pantoprazole

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2021-02-06
Completion:: 2022-02-28

Conditions

Healthy Volunteers - Male and Female

Interventions

DRUG

No Results Yet

NCT07262723 | NOT_YET_RECRUITING | PHASE2/PHASE3

332 participants

Levosimendan in Acute Decompensated Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-12-01
Completion:: 2026-10-30

Conditions

Acute Decompensated Heart Failure (ADHF)

Interventions

DRUG
OTHER

No Results Yet

NCT07262710 | NOT_YET_RECRUITING

13656 participants

Association of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers With Post-Stroke Pneumonia: A Real-World Retrospective Cohort Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-12-01
Completion:: 2026-08-01

Conditions

Post-stroke Pneumonia

Interventions

DRUG

No Results Yet

NCT07262697 | COMPLETED | NA

60 participants

Laser Therapy for Patients With Nonspecific Neck Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2023-03-01
Completion:: 2024-03-01

Conditions

Neck Pain
Non Specific Neck Pain

Interventions

OTHER

No Results Yet

NCT07262684 | COMPLETED | NA

32 participants

Resilience Training for University Students After the Earthquakes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-02-10
Completion:: 2025-08-30

Conditions

Psychological Resilience
Psychological Well-being

Interventions

BEHAVIORAL

No Results Yet

NCT07262671 | ACTIVE_NOT_RECRUITING

100 participants

Predictive Value of Exosomes in Pleural Effusion for Advanced Lung Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-10-16
Completion:: 2027-10-16

Conditions

NSCLC (Advanced Non-small Cell Lung Cancer)

No Results Yet

NCT07257614 | NOT_YET_RECRUITING

40 participants

Left Atrial Appendage Occlusion in Dialysis Patients With Atrial Fibrillation: A Multicentre Pilot Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-04
Start Date:: 2026-01-05
Completion:: 2028-01-05

Conditions

Dialysis
Chronic Kidney Disease (Stages 3b-5)
Atrial Fibrillation
End Stage Kidney Failure
Stroke Prevention in Patients With Atrial Fibrillation
Left Atrial Appendage Occlusion

No Results Yet

NCT07257393 | NOT_YET_RECRUITING

100 participants

Fall Risk Assessment in Parkinson's Disease Using Kinetikos Health

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-12-01
Completion:: 2026-06-30

Conditions

Idiopathic Parkinsonism

Interventions

OTHER

No Results Yet

NCT07255092 | NOT_YET_RECRUITING | NA

30 participants

Mechanisms Underlying the Nocibo Effect of Contagious Itch. in Both Histaminergic and Nonhistaminergic Itch

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-12-01
Completion:: 2026-12-31

Conditions

ITCH

Interventions

OTHER

No Results Yet

NCT07254832 | COMPLETED | NA

20 participants

Effects of Caffeine and Nicotine Gum on Balance Performance in Athletes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2024-01-08
Completion:: 2024-04-05

Conditions

Athletic Performance
Postural Stability
Healhty

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT07253454 | NOT_YET_RECRUITING

800 participants

Combined Use of Machine Learning and Metabolomics to Improve the Diagnosis and Management of Hyperandrogenism

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-04
Start Date:: 2026-01-31
Completion:: 2040-12-31

Conditions

Hyperandrogenism

Interventions

OTHER

No Results Yet

NCT07252336 | RECRUITING | PHASE2

50 participants

A Multicenter Study of CAR-T Cells in Primary Ph+All

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-04
Start Date:: 2025-11-30
Completion:: 2027-11-30

Conditions

ALL

Interventions

DRUG

No Results Yet