Clinical Trials

NCT05630066 | COMPLETED | PHASE2

48 participants

A Study to Investigate the Pharmacokinetics (PK) and Safety and to Provide Proof of Mechanism of Alogabat in Children and Adolescents Aged 5-17 Years With Angelman Syndrome (AS) With Deletion Genotype.

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2023-07-27

Completion:

2025-12-02

Conditions

• Angelman Syndrome

Interventions

• DRUG

No Results Yet

NCT05591677 | ACTIVE_NOT_RECRUITING | PHASE2

180 participants

D-Cycloserine Augmentation of Intermittent Theta Burst Stimulation (iTBS) in Depression (COGENT)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2023-04-21

Completion:

2026-05-29

Conditions

• Major Depressive Disorder

Interventions

• DRUG
• DEVICE

No Results Yet

NCT05585229 | RECRUITING | PHASE2

10 participants

Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2025-10-27

Completion:

2026-08-31

Conditions

• Opioid Dependence
• Chronic Pain

Interventions

• DRUG

No Results Yet

NCT05579847 | COMPLETED

20 participants

Feasibility of a Smart-Phone App for Patients With Advanced Renal Cell Carcinoma Undergoing Combination Immunotherapy

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2022-10-19

Completion:

2024-01-07

Conditions

• Renal Cell Carcinoma Stage IV

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT05566483 | RECRUITING | NA

30 participants

Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2023-03-01

Completion:

2027-10-31

Conditions

• Post-acute Sequelae of SARS-CoV-2 Infection

Interventions

• BEHAVIORAL

No Results Yet

NCT05558501 | RECRUITING | PHASE1/PHASE2

60 participants

Intermittent Hypoxia-initiated Plasticity in Humans: A Multi-pronged Therapeutic Approach to Treat Sleep Apnea and Overlapping Co-morbidities

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2023-01-01

Completion:

2026-12-31

Conditions

• Obstructive Sleep Apnea

Interventions

• OTHER

No Results Yet

NCT05553041 | RECRUITING | EARLY_PHASE1

30 participants

18F-Fluciclovine PET-MRI in High-grade Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2024-08-07

Completion:

2026-12-31

Conditions

• Glioma
• High Grade Glioma
• Glioma, Malignant
• Glioma Intracranial
• Diffuse Glioma

Interventions

• DRUG

No Results Yet

NCT05548699 | COMPLETED

1290 participants

Precision Mental Health in Diabetes - Subtypes of Mental Health, Trajectories, and Patterns With Glycaemic Control

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2023-05-02

Completion:

2024-12-31

Conditions

• Diabetes Mellitus
• Depressive Disorder
• Depressive Symptoms
• Anxiety Disorders
• Anxiety and Fear
• Eating Disorders
• Eating Disorder Symptom
• Eating Behavior
• Hyperglycemia
• Emotional Distress

No Results Yet

NCT05526989 | RECRUITING | PHASE2

25 participants

Study of the Combination Dostarlimab With Niraparib In Patients With Penile Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2022-12-28

Completion:

2026-11-30

Conditions

• Penile Carcinoma

Interventions

• DRUG

No Results Yet

NCT05520723 | COMPLETED | PHASE2

50 participants

Preventive stRategy for IMMU132-relatED AEs in TNBC or Luminal Breast Cancer- PRIMED

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2023-02-06

Completion:

2023-10-18

Conditions

• Triple Negative Breast Cancer
• Breast Cancer
• Advanced HR+/HER2- Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05516758 | TERMINATED | PHASE2

491 participants

A Study of Peresolimab (LY3462817) in Participants With Moderately-to-Severely Active Rheumatoid Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2022-08-31

Completion:

2023-11-20

Conditions

• Rheumatoid Arthritis
• Arthritis
• Joint Diseases
• Musculoskeletal Diseases
• Rheumatic Diseases
• Connective Tissue Diseases
• Autoimmune Diseases
• Immune System Diseases

Interventions

• DRUG

Results Available

NCT05508399 | COMPLETED

28 participants

Biomarker Analysis of Tislelizumab Combined With Chemotherapy for Perioperative Treatment of G/GEJ Adenocarcinoma

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2022-07-18

Completion:

2024-01-10

Conditions

• Locally Advanced Gastric Adenocarcinoma
• PD-1

Interventions

• OTHER

No Results Yet

NCT05507437 | COMPLETED | PHASE2

20 participants

Pharmacokinetics and Safety of TIN816 in Patients With Sepsis-associated Acute Kidney Injury

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2022-11-22

Completion:

2024-04-25

Conditions

• Acute Kidney Injury Due to Sepsis

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT05486897 | COMPLETED

315 participants

Periventricular White Matter Hyperintensities in Cerebral Amyloid Angiopathy and Hypertensive Arteriopathy

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2022-09-05

Completion:

2023-12-15

Conditions

• Cerebral Amyloid Angiopathy
• Hypertensive Arteriopathy

Interventions

• OTHER

No Results Yet

NCT05470712 | COMPLETED

26 participants

Vital Mechanism of NETs Formation vs. Suicidal Mechanism of NETs Formation During Normal Pregnancy and Preeclampsia

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2022-07-20

Completion:

2022-12-31

Conditions

• Pre-Eclampsia

No Results Yet

NCT05454150 | ACTIVE_NOT_RECRUITING | NA

1960 participants

Balloon-Expandable Versus Self-expanding Transcatheter Heart Valve for Treatment of Symptomatic Native Aortic Valve Stenosis (BEST)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2023-04-19

Completion:

2025-10-29

Conditions

• Aortic Valve Stenosis

Interventions

• DEVICE

No Results Yet

NCT05430204 | COMPLETED | NA

1628 participants

Continuous Glucose Monitoring for Screening for Diabetes in Pregnancy

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2023-03-07

Completion:

2024-08-02

Conditions

• Gestational Diabetes

Interventions

• DEVICE

Results Available

NCT05415605 | COMPLETED | NA

30 participants

Ultrasound Evaluation of Alveolar Stress by Measurement of Ultrasound Pleural Strain in Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2022-07-24

Completion:

2022-07-27

Conditions

• Ultrasound Strain Measurement

Interventions

• DEVICE

No Results Yet

NCT05413824 | COMPLETED

2233 participants

Neutrophil Side Fluorescent Light (NEU-SFL) in COVID-19 Patients

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2022-06-02

Completion:

2022-12-31

Conditions

• COVID-19

No Results Yet

NCT05410951 | ACTIVE_NOT_RECRUITING

800 participants

LobularCard Trial: Searching for Novel Germline Mutations in Lobular Breast Cancer Patients

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2022-05-16

Completion:

2025-12-31

Conditions

• Lobular Breast Carcinoma
• Lobular in Situ Breast Carcinoma
• BRCA1 Mutation
• BRCA2 Mutation

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05402579 | COMPLETED

63 participants

Diabetic Ketoacidosis From New SGLT2i: Can Genomics Estimate Risk

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2022-07-29

Completion:

2025-01-20

Conditions

• Diabetes Type 2
• DKA
• Diabetic Ketoacidosis

Interventions

• GENETIC

No Results Yet

NCT05398484 | RECRUITING | PHASE2/PHASE3

200 participants

Psilocybin Therapy in Advanced Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2023-05-24

Completion:

2027-01-01

Conditions

• Advanced Cancer

Interventions

• DRUG
• BEHAVIORAL

No Results Yet

NCT05394636 | COMPLETED

111 participants

Cerebellar Superficial Siderosis in Cerebral Amyloid Angiopathy

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2022-06-01

Completion:

2022-12-31

Conditions

• Cerebral Amyloid Angiopathy
• Siderosis

Interventions

• OTHER

No Results Yet

NCT05372263 | RECRUITING

700 participants

Safety Surveillance of Targeted Drugs for Pulmonary Hypertension Using a Computerized Follow-up System: a Nationwide Cohort Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2021-08-26

Completion:

2026-08-31

Conditions

• Pulmonary Hypertension

No Results Yet

NCT05366153 | RECRUITING

748 participants

Risk-guided Disease managEment Plan to prevEnt CAD in Patients Treated With Previous Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2023-10-18

Completion:

2026-05-31

Conditions

• Coronary Artery Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05358704 | SUSPENDED | PHASE2

38 participants

Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2022-05-13

Completion:

2027-12-30

Conditions

• Cancer of Rectum

Interventions

• DRUG

No Results Yet

NCT05353023 | COMPLETED

1594801 participants

Intensive Care Unit Activity in France From the National Database Between 2013 and 2019

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2013-01-01

Completion:

2023-12-31

Conditions

• Critical Illness
• Intensive Care Unit

No Results Yet

NCT05352997 | COMPLETED

156 participants

Beta-lactams Therapeutic Drug Monitoring in Critically Ill Patients

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2018-01-01

Completion:

2022-12-31

Conditions

• Infectious Disease

No Results Yet

NCT05352815 | COMPLETED | PHASE3

1291 participants

A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Insulin Icodec

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2022-06-01

Completion:

2024-03-19

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

Results Available

NCT05349526 | COMPLETED

206 participants

Anatomical Relationship Between Carotid Artery and Hyoid Bone in Stenotic and Non-stenotic Carotids

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2022-02-15

Completion:

2022-08-15

Conditions

• Stenoses, Carotid
• Stroke

Interventions

• OTHER

No Results Yet

NCT05337098 | RECRUITING | NA

30 participants

Non-Nutritive Sweetener Consumption and Glucose Homeostasis in Older Adults With Prediabetes

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2023-04-18

Completion:

2026-02-28

Conditions

• Continuous Glucose Monitoring
• Oral Glucose Tolerance
• Insulin Sensitivity
• Inflammatory Markers

Interventions

• OTHER

No Results Yet

NCT05326386 | ACTIVE_NOT_RECRUITING | NA

84 participants

Gamification and Medication Adherence (GAME Adherence)

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2022-09-12

Completion:

2024-01-31

Conditions

• Hypertension and Hyperlipidemia

Interventions

• BEHAVIORAL

No Results Yet

NCT05310396 | COMPLETED | NA

240 participants

Efficacy of a Nutrient Blend in Improving Neurocognitive and Behavioral Outcomes in Infants: a Randomized, Controlled, Intervention Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2022-10-07

Completion:

2025-07-18

Conditions

• Infant Nutrition
• Cognitive Development

Interventions

• OTHER

No Results Yet

NCT05301283 | RECRUITING | PHASE2

43 participants

Habitat Escalated Adaptive Therapy (HEAT), With Neoadjuvant Radiation for Soft Tissue Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2022-05-18

Completion:

2026-08-31

Conditions

• High Grade Sarcoma

Interventions

• RADIATION
• DIAGNOSTIC_TEST

No Results Yet

NCT05253911 | COMPLETED

49 participants

Tucatinib in Patients With Locally Advanced or Metastatic HER2-positive Breast Cancer Who Received at Least Two Prior Anti-HER2 Treatment Regimens.

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2022-05-21

Completion:

2025-06-30

Conditions

• HER2-positive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05227677 | COMPLETED | NA

200 participants

Value of Glycated Albumin in Intervention of Glycemic Control in Chinese Patients With Type 2 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2022-08-15

Completion:

2024-08-31

Conditions

• Type 2 Diabetes Mellitus

Interventions

• OTHER

Results Available

NCT05226689 | ACTIVE_NOT_RECRUITING | NA

31 participants

Porous Baseplate in Total Knee Replacement

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2022-04-11

Completion:

2025-04-08

Conditions

• Knee Osteoarthritis

Interventions

• DEVICE

No Results Yet

NCT05224570 | COMPLETED

120 participants

Epidemiology of Gunshot Wounds Injuries Admitted in ICU in France

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2015-01-01

Completion:

2022-06-17

Conditions

• Gunshot Wound

No Results Yet

NCT05208879 | COMPLETED

10 participants

CArotenoid in hypoChOlesterolemia

Study Type:

OBSERVATIONAL

Last Updated:

2025-12-04

Start Date:

2022-06-30

Completion:

2024-11-07

Conditions

• Primary Intestinal Hypocholesterolemia
• Abetalipoproteinemia
• Chylomicron Retention Disease

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT05201547 | ACTIVE_NOT_RECRUITING | PHASE3

260 participants

Endometrial Cancer Patientes MMR Deficient Comparing Chemotherapy vs Dostarlimab in First Line

Study Type:

INTERVENTIONAL

Last Updated:

2025-12-04

Start Date:

2022-04-15

Completion:

2026-04-30

Conditions

• Endometrial Cancer

Interventions

• DRUG

No Results Yet