Clinical Trials Updated in 2025

NCT04844528 | RECRUITING | PHASE2

86 participants

Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2022-02-25
Completion:: 2026-08-31

Conditions

Chronic Lymphocytic Leukemia
Non-melanoma Skin Cancer (NMSC)

Interventions

DRUG

No Results Yet

NCT04835831 | ACTIVE_NOT_RECRUITING | NA

115 participants

Interest of APA in Fatty Liver Disease Evaluation of Efficacy and Adherence to an Adapted Physical Activity (APA) Program in Patients With Metabolic Fatty Liver Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2021-09-15
Completion:: 2022-06-15

Conditions

Non-Alcoholic Fatty Liver Disease (NAFLD

Interventions

OTHER

No Results Yet

NCT04832971 | COMPLETED | PHASE2

204 participants

Study of ARO-ANG3 in Adults With Mixed Dyslipidemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2021-06-28
Completion:: 2022-08-30

Conditions

Mixed Dyslipidemia

Interventions

DRUG

Results Available

NCT04829929 | ACTIVE_NOT_RECRUITING | NA

200 participants

Evaluation of Safety and Performance of the Omega™ LAA (Left Atrial Appendage) Occluder and Omega™ Delivery System in Patients With Non-Valvular Atrial Fibrillation and High Bleeding Risk

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-11-17
Completion:: 2025-02-19

Conditions

Non-Valvular Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT04829565 | ACTIVE_NOT_RECRUITING | PHASE4

60 participants

Assessment of Pain After Intra-articular Botulinum Toxin Injections in Carpometacarpal Osteoarthritis of the Thumb

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2021-09-09
Completion:: 2025-05-15

Conditions

Rhizarthrosis

Interventions

DRUG

No Results Yet

NCT04826458 | COMPLETED | NA

124 participants

Clinical Study Comparing Different Strategies to Increase Adherence to Oral Therapies in Oncohematology

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2021-05-04
Completion:: 2025-11-11

Conditions

Cancer
Solid Tumor
Hematologic Malignancy
Oral Drug Administration

Interventions

DEVICE
OTHER

No Results Yet

NCT04798924 | ACTIVE_NOT_RECRUITING | NA

60 participants

Visual Rehabilitation After Occipital Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2021-07-19
Completion:: 2025-09-26

Conditions

Stroke, Ischemic
Quadrantanopia
Vision Loss Partial
Visual Field Defect, Peripheral
Peripheral Visual Field Defect of Both Eyes
Peripheral Visual Field Defect
Hemianopsia
Hemianopia
Homonymous Hemianopia
Homonymous Hemianopsia
Visual Fields Hemianopsia
Occipital Lobe Infarct
Quadrantanopsia
Stroke Hemorrhagic

Interventions

DEVICE

No Results Yet

NCT04780880 | WITHDRAWN

0 participants

Incidence and Prognostic Factors for Lower Extremities Injuries in Polish Youth Soccer Academy.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2021-01-05
Completion:: 2025-01-10

Conditions

Musculoskeletal Diseases
Athletic Injuries

No Results Yet

NCT04740645 | COMPLETED

1099551 participants

NOCDURNA PASS Study Using Registries in Denmark, Germany and Sweden

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2021-07-13
Completion:: 2023-11-01

Conditions

Adverse Drug Event

Interventions

OTHER

No Results Yet

NCT04736511 | COMPLETED | NA

41 participants

Influence of Proprioceptive Reweighting Ability on Lower-limb Biomechanics During Functional Tasks

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2021-02-15
Completion:: 2021-04-16

Conditions

Anterior Cruciate Ligament Injuries

Interventions

OTHER

No Results Yet

NCT04704219 | COMPLETED | PHASE2

160 participants

Pembrolizumab Plus Lenvatinib for First-line Advanced/Metastatic Non-clear Cell Renal Cell Carcinoma (1L nccRCC) (MK-3475-B61)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2021-02-23
Completion:: 2025-01-27

Conditions

Renal Cell Carcinoma

Interventions

BIOLOGICAL
DRUG

Results Available

NCT04685967 | ACTIVE_NOT_RECRUITING | NA

23 participants

Clinical Evaluation of a Restorative Glass Ionomer and a Bulk-fill Composite Resin

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2021-03-15
Completion:: 2021-08-15

Conditions

Tooth Disease

Interventions

DEVICE

No Results Yet

NCT04680533 | TERMINATED | PHASE1/PHASE2

3 participants

Wireless TENS for Peripheral Edema (Lower Limb Swelling)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2021-06-28
Completion:: 2024-02-22

Conditions

Peripheral Edema

Interventions

DEVICE

Results Available

NCT04668651 | WITHDRAWN

0 participants

Preoperative Evaluation of Gastric Contents by Antral Ultrasound in Diabetic Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2021-01-12
Completion:: 2021-04-05

Conditions

Diabetes

Interventions

OTHER

No Results Yet

NCT04620369 | COMPLETED | PHASE3

106 participants

Rose Geranium in Sesame Oil Nasal Spray for the Improvement of Nasal Vestibulitis Symptoms in Cancer Patients Receiving Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-11-13
Completion:: 2022-12-15

Conditions

Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm
Nasal Vestibulitis

Interventions

DRUG
OTHER

Results Available

NCT04598646 | COMPLETED | NA

30 participants

The Harmonized Interventions to Maintain Health Via Appropriate Risk Factor Modification and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2022-04-01
Completion:: 2023-10-20

Conditions

Heart Failure
Cardiotoxicity
Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT04596540 | COMPLETED | PHASE3

153 participants

A Study of SEL-212 in Patients With Gout Refractory to Conventional Therapy II

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-11-30
Completion:: 2023-01-10

Conditions

Chronic Gout

Interventions

DRUG
OTHER

Results Available

NCT04562285 | COMPLETED

829 participants

Sustained Immunity to COVID-19 as Measured by SARS-CoV-2 Serology Assays

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-06-23
Completion:: 2021-05-28

Conditions

Covid19

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04556305 | COMPLETED | NA

253 participants

Lifestyle Physical Activity and Cognitive Training Interventions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-10-05
Completion:: 2024-01-12

Conditions

Cognitive Decline
Cardiovascular Diseases
Cognitive Dysfunction
Cognitive Impairment
Mild Cognitive Impairment

Interventions

BEHAVIORAL

Results Available

NCT04464668 | ACTIVE_NOT_RECRUITING

49 participants

Colorectal Cancer Awareness, Research and Education and Screening - Rural Expansion, Access and Capacity for Health

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-06-25
Completion:: 2027-10-26

Conditions

Colorectal Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT04373005 | TERMINATED

83 participants

Screening of Cancer Patients to Assess Impact of COVID-19

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-05-11
Completion:: 2022-10-06

Conditions

Covid-19
Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04340466 | COMPLETED

1003 participants

French Multicentre Observational Study on SARS-Cov-2 Infections (COVID-19) ICU Management Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-04-03
Completion:: 2020-07-03

Conditions

Pneumonia, Viral
Critically Ill
Corona Virus Infection

Interventions

OTHER

No Results Yet

NCT04328623 | COMPLETED | NA

80 participants

Interest of Hypnosis on Pain Management During a Guided Echo Infiltration of the Hand

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-10-08
Completion:: 2022-09-02

Conditions

Hand Injuries

Interventions

PROCEDURE

Results Available

NCT04324008 | ACTIVE_NOT_RECRUITING | NA

28 participants

Clinical Comparison of Different Flowable Resin Composites

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2017-11-01
Completion:: 2018-01-01

Conditions

Tooth Diseases

Interventions

DEVICE

No Results Yet

NCT04314206 | COMPLETED | PHASE1

36 participants

VNRX-5024 Safety and PK in Healthy Adult Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-07-27
Completion:: 2020-12-31

Conditions

Healthy Subjects

Interventions

DRUG

No Results Yet

NCT04279834 | COMPLETED | NA

558 participants

Improving Outcomes for Patients With SDB and Insufficient Sleep

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-10-16
Completion:: 2025-08-11

Conditions

Sleep Apnea
Insufficient Sleep Syndrome
Sleep
Hypertension

Interventions

BEHAVIORAL

No Results Yet

NCT04248569 | RECRUITING | PHASE1

56 participants

DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-04-20
Completion:: 2029-03-01

Conditions

Fibrolamellar Hepatocellular Carcinoma (FLC)

Interventions

DRUG

No Results Yet

NCT04243863 | COMPLETED | PHASE1

83 participants

VNRX-7145 SAD/MAD Safety and PK in Healthy Adult Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-01-20
Completion:: 2021-04-05

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT04239690 | COMPLETED | NA

201 participants

Preservation of Blood in Extremely Preterm Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-03-15
Completion:: 2024-06-15

Conditions

Bronchopulmonary Dysplasia

Interventions

OTHER

No Results Yet

NCT04224948 | COMPLETED | NA

18 participants

The PET- Retroperitoneal Sarcoma Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-01-03
Completion:: 2024-12-31

Conditions

Retroperitoneal Sarcoma

Interventions

DEVICE

No Results Yet

NCT04205383 | COMPLETED

115 participants

GROSS-HIST : Quantification of the Main Circulating Histones During Normal Pregnancy and Pregnancies With Placenta-mediated Complications

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2019-03-01
Completion:: 2019-11-05

Conditions

Pregnancy
Pregnancy Complications
Healthy Volunteers

Interventions

OTHER

No Results Yet

NCT04204850 | RECRUITING | PHASE2

20 participants

Cabozantinib to Treat Recurrent Liver Cancer Post Transplant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-08-07
Completion:: 2026-06-01

Conditions

Hepatocellular Carcinoma
Recurrent Cancer
Liver Transplant

Interventions

DRUG

No Results Yet

NCT04180436 | COMPLETED | PHASE1

67 participants

Pharmacokinetics of Rivaroxaban After Bariatric Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-01-15
Completion:: 2022-06-21

Conditions

Bariatric Surgery
Morbid Obesity

Interventions

DRUG

No Results Yet

NCT04179539 | COMPLETED | NA

100 participants

Ga68 V/Q PET/CT for Pulmonary Embolism Diagnosis: a Diagnostic Accuracy Study vs CT Pulmonary Angiography

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2019-12-06
Completion:: 2024-11-06

Conditions

Pulmonary Embolism

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04163315 | ACTIVE_NOT_RECRUITING | NA

30 participants

Multimodal Connectome Study of Brain Tumor-operated Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2019-12-12
Completion:: 2020-01-12

Conditions

Tumor, Brain

Interventions

OTHER

No Results Yet

NCT04159987 | ACTIVE_NOT_RECRUITING | NA

20 participants

Monitoring to the Evolution of Motor Function in SMA Type II Adults Patients Treated With SPINRAZA®

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-02-25
Completion:: 2024-07-19

Conditions

Spinal Muscular Atrophy

Interventions

OTHER

No Results Yet

NCT04157322 | ACTIVE_NOT_RECRUITING

55 participants

Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2019-08-26
Completion:: 2027-10-31

Conditions

Colorectal Cancer Stage IV
Colorectal Cancer Metastatic
Colorectal Cancer, Genetics of
Appendix Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04151342 | RECRUITING

5500 participants

CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-03
Start Date:: 2020-01-17
Completion:: 2029-12-31

Conditions

Cancer
Malignancies Multiple
Malignant Solid Tumor
Cancer, Therapy-Related
Molecular Sequence Variation
Genetic Alteration
Gene Fusion
Receptor Tyrosine Kinase Gene Mutation
RTK Family Gene Mutation
Ras (Kras or Nras) Gene Mutation

Interventions

DRUG
OTHER

No Results Yet

NCT04099108 | COMPLETED | NA

50 participants

Effect of Combined IV Bolus Amino Acid Supplementation and Mobilisation on Skeletal Muscle During the First 10 Days in the ICU: A RCT

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2021-05-24
Completion:: 2022-09-09

Conditions

Critical Illness

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT04090632 | COMPLETED | NA

82 participants

Impact of Anthropometrics Data and of Physical Activity Level in Closed kineTic Chain Upper Extremity Stability Test

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-03
Start Date:: 2019-11-25
Completion:: 2020-01-27

Conditions

Shoulder Pain

Interventions

DIAGNOSTIC_TEST

No Results Yet