Clinical Trials Updated in 2025

NCT07254858 | NOT_YET_RECRUITING | PHASE2

302 participants

Combined Chemo-immunotherapy Plus SBRT in Neoadjuvant Treatment for Luminal Subtype Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-12-31
Completion:: 2026-12-30

Conditions

HR+/HER2- Breast Cancer

Interventions

RADIATION
DRUG

No Results Yet

NCT07254845 | NOT_YET_RECRUITING | PHASE1

30 participants

A PROSPECTIVE, SINGLE-CENTERED, ASSESSOR-BLINDED STUDY TO EVALUATE THE CLINICAL EFFICACY OF THE PROPOSED CELL/TISSUE HISTOPATHOLOGY PROCESSOR CCELL (CONFOCAL FLUORESCENCE ENDOMICROSCOPY) FOR INTRAOPERATIVE DIAGNOSIS IN BRAIN TUMORS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-12-01
Completion:: 2026-05-30

Conditions

Frozen Sections
Indocyanine Green (ICG)
Brain Tumor

Interventions

DEVICE
DRUG

No Results Yet

NCT07254767 | NOT_YET_RECRUITING | NA

10 participants

Virtual Walking and Neuromulation to Reduce Neuropathic Pain After a Spinal Cord Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-12-01
Completion:: 2027-05-31

Conditions

Neuropathic Pain

Interventions

DEVICE

No Results Yet

NCT07254754 | RECRUITING | PHASE2

45 participants

Study to Evaluate the Efficacy of Axicabtagene Ciloleucel in Patients With Late Relapse of Diffuse Large B-Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-11-20
Completion:: 2027-01-31

Conditions

DIFFUSE LARGE B-CELL LYMPHOMA

Interventions

DRUG

No Results Yet

NCT07254741 | COMPLETED | NA

2000 participants

Pharmacist Mobile App Intervention in Pediatric Inpatient

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-03-12
Completion:: 2024-09-12

Conditions

Medication Safety in Pediatric Inpatients

Interventions

BEHAVIORAL

No Results Yet

NCT07254715 | RECRUITING | PHASE4

60 participants

Effect of Itopride on Semaglutide Gastroparesis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-12-31
Completion:: 2026-04-30

Conditions

Semaglutide-Induced Gastric Motility
Anesthesia

Interventions

DRUG

No Results Yet

NCT07254663 | RECRUITING

500 participants

GEL & MEDication Dysphagia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-09-15
Completion:: 2027-09-15

Conditions

Neurological Diseases or Conditions
Healthy Participants

Interventions

OTHER

No Results Yet

NCT07254611 | COMPLETED

15 participants

Combination of HMA and Venetoclax With Posaconazole in Patients With Acute Myeloid Leukemia: A Study of Plasma Concentrations

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2022-04-12
Completion:: 2023-02-15

Conditions

AML (Acute Myelogenous Leukemia

No Results Yet

NCT07254598 | NOT_YET_RECRUITING | NA

84 participants

Myotensive Extraocular Muscle Techniques Added to Manual Therapy for Migraine Without Aura

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2026-01-08
Completion:: 2026-06-30

Conditions

Migraine Without Aura

Interventions

OTHER

No Results Yet

NCT07254572 | RECRUITING | PHASE4

300 participants

Anti-atherosclerotic Efficacy of Selected Antidiabetic Drugs in Patients With Coronary Artery Disease and Pre-diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-07-10
Completion:: 2029-08-01

Conditions

Coronary Artery Disease
PreDiabetes

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT07254546 | NOT_YET_RECRUITING | NA

15 participants

A Qualitative Study on Gratitude and Recognition Toward Living Kidney Donors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2026-01-01
Completion:: 2026-08-01

Conditions

Kidney Transplantation
Nephrectomy,Kidney Donation

Interventions

BEHAVIORAL

No Results Yet

NCT07254533 | NOT_YET_RECRUITING | NA

90 participants

Diagnosis and Quantification of Hepatic Steatosis Using Near-infrared Spectroscopy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2026-01-31
Completion:: 2027-01-31

Conditions

Hepatic Transplantation
Steatohepatitis

Interventions

DEVICE

No Results Yet

NCT07254507 | COMPLETED | NA

80 participants

Lung Ultrasound-Guided Positioning Strategy for the Prevention of Ventilator-Associated Pneumonia in Neonates

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-01-01
Completion:: 2025-10-01

Conditions

Pneumonia

Interventions

BEHAVIORAL

No Results Yet

NCT07254494 | RECRUITING | NA

30 participants

Guided Bone Regeneration in Lower Posterior Edentulous Arch Using Resorbable or Non Resorbable Membrane.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2026-05-31
Completion:: 2026-12-31

Conditions

Horizontal Alveolar Bone Defect
Guided Bone Regeneration

Interventions

PROCEDURE

No Results Yet

NCT07254481 | RECRUITING | PHASE1

86 participants

VB19055 Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study in a Healthy Chinese Population

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-10-05
Completion:: 2026-07-31

Conditions

Hypertension

Interventions

DRUG

No Results Yet

NCT07254442 | COMPLETED

90 participants

Investigation of the Impact of Medications Used in COVID-19 Treatment and COVID-19 Vaccine on Hearing

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2021-12-01
Completion:: 2022-02-01

Conditions

Hearing
COVID - 19
Ototoxicity

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07254416 | NOT_YET_RECRUITING | PHASE4

120 participants

A Study on Nausea and Vomiting Caused by T-DXd in Breast Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-12-15
Completion:: 2026-12-31

Conditions

Breast Cancer Patients Treated With T-DXd

Interventions

DRUG

No Results Yet

NCT07254403 | RECRUITING | NA

60 participants

Anabolic Response to Beef vs Plant Protein in (Pre)Frail Older Adults Using a Novel Stable Isotope Pulse Method

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-10-31
Completion:: 2026-12-31

Conditions

Protein Metabolism

Interventions

OTHER

No Results Yet

NCT07254312 | RECRUITING

14 participants

Correlation of Venetoclax Plasma Concentrations With Toxicity of Hypometilating Agents and Venetoclax Combination for Acute Myeloid Leukemia Patients in Remission.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-10-21
Completion:: 2026-04-30

Conditions

AML (Acute Myelogenous Leukemia

No Results Yet

NCT07254273 | COMPLETED | NA

22 participants

Boccia Exercises and Upper Limb Muscle Adaptations in Hemiparetic Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-10-24
Completion:: 2024-11-01

Conditions

Hemiparesis After Stroke

Interventions

OTHER

No Results Yet

NCT07254260 | COMPLETED

95 participants

Photodynamic Therapy and Post-Endodontic Pain in Undergraduate-Performed Treatments

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-01-01
Completion:: 2025-09-30

Conditions

Pulpitis

Interventions

DEVICE

No Results Yet

NCT07254234 | NOT_YET_RECRUITING

200 participants

A Study of Retinal Imaging to Detect Abnormal Protein Deposits Associated With Alzheimer's Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-12-31
Completion:: 2026-08-31

Conditions

Cognitive Dysfunction
Memory Disorders

Interventions

OTHER

No Results Yet

NCT07254182 | COMPLETED | NA

39 participants

Hand Cooling With Ice Packs in Healthy Young Men

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2018-04-12
Completion:: 2018-07-11

Conditions

Cold Exposure
Body Temperature Regulation
Thermal Comfort Perception

Interventions

OTHER

No Results Yet

NCT07254156 | NOT_YET_RECRUITING

229 participants

A Study of Tumor-Agnostic MRD Detection in Stage III Colorectal Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-11-24
Completion:: 2028-12-31

Conditions

Colorectal Cancer
MRD
ctDNA

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07254143 | COMPLETED

16 participants

Clinical And Radiographic Efficacy Of MTA Flow In Apicoectomy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2021-10-21
Completion:: 2022-10-21

Conditions

Clinical and Radiographic Success in 6 Months

Interventions

DRUG

No Results Yet

NCT07254130 | COMPLETED | NA

209 participants

COMPARISON OF MEAN DURATION OF POST OPERATIVE ANALGESIA FOLLOWING ADDITION OF DEXMEDETOMIDINE TO ROPIVACAINE VERSUS PLAIN ROPIVACAINE ON ULTRASOUND GUIDED RECTUS SHEATH BLOCK

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-02-28
Completion:: 2025-08-28

Conditions

Midline Laparotomy

Interventions

PROCEDURE

No Results Yet

NCT07254117 | RECRUITING

46 participants

The Role of Granulation Tissue in Periodontal Regeneration

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-05-29
Completion:: 2026-09-30

Conditions

Periodontal Bone Loss
Periodontitis
Periodontal Disease
Periodontal Diseases
Periodontal Regeneration
Periodontal Granulation Tissue
Vertical Periodontal Bone Defects
Periodontal Healing

No Results Yet

NCT07254104 | ENROLLING_BY_INVITATION | EARLY_PHASE1

30 participants

Clinical Evaluation of [68Ga]Ga-NOTA-RF PET Imaging Targeting RFVT3 in Patients With Pituitary Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-11-17
Completion:: 2026-10-13

Conditions

Pituitary Neoplasms

Interventions

DRUG

No Results Yet

NCT07254065 | RECRUITING | NA

130 participants

Starting Early to Prevent Obesity Using Telehealth (StEP OUT): Pilot RCT

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-11-14
Completion:: 2027-12-31

Conditions

Feasibility and Acceptability
Prevention Childhood Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT07254052 | COMPLETED

32 participants

Effectiveness of Ammonium Chloride in Reducing Viral Load

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-09-01
Completion:: 2025-04-30

Conditions

RNA Virus Infections
Viral Infection COVID-19
Influenza A and B

No Results Yet

NCT07254039 | NOT_YET_RECRUITING

200 participants

AI-Assisted Saliva Diagnostics Using an Electrochemical Sensor Platform for Periodontitis Detection (SALIENCE)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-12-01
Completion:: 2027-12-31

Conditions

Periodontal Diseases
Biomarkers (D23.050.301)
Diagnostic
Saliva

No Results Yet

NCT07254026 | RECRUITING | NA

300 participants

Precision Health and Smart Telerehabilitation in OSA

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-10-15
Completion:: 2029-12-31

Conditions

Obstructive Sleep Apnea

Interventions

PROCEDURE
DEVICE
OTHER

No Results Yet

NCT07254000 | RECRUITING | PHASE2

24 participants

Anakinra Pilot 2 - A Study to Optimise Dose and Route of Administration of Anakinra in Preterm Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-06-27
Completion:: 2026-06-30

Conditions

Premature Infants
Very Premature Infants
Inflammation

Interventions

DRUG

No Results Yet

NCT07253961 | NOT_YET_RECRUITING | NA

150 participants

Cold-Induced Vagal Stimulation for Attenuating Venipuncture Pain in Obese Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-12-01
Completion:: 2026-01-20

Conditions

Venipuncture Pain
Vagal Nerve Stimulation
Cold Stimulation

Interventions

PROCEDURE

No Results Yet

NCT07253948 | RECRUITING

231 participants

Distribution Characteristics of Helicobacter Pylori

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-10-22
Completion:: 2025-12-31

Conditions

Helicobacter Pylori
Early Gastric Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07253935 | NOT_YET_RECRUITING | NA

112 participants

Impact of Therapeutic Exercise Integrated With Psychotherapy and Education in Patients With Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-12-01
Completion:: 2027-02-28

Conditions

Depression Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07253922 | COMPLETED

40 participants

Evaluation of Optic Nerve Sheath Diameter Changes During Cardiopulmonary Bypass in Open Heart Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-06-10
Completion:: 2025-10-10

Conditions

Open Heart Surgery
Cardiopulmonary Bypass
Intracranial Pressure
Optic Nerve Sheath Diameter

Interventions

PROCEDURE

No Results Yet

NCT07253909 | ENROLLING_BY_INVITATION

72 participants

Upper Extremity Function in Patients With Reduced Ejection Fraction Heart Failure and Cardiac Implantable Electronic Devices

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-05-30
Completion:: 2026-08-30

Conditions

Heart Failure
Implantable Cardioverter Defibrillator (ICD)
Cardiac Resynchronisation Therapy (CRT)
Reduced Ejection Fraction Heart Failure

Interventions

OTHER

No Results Yet

NCT07253896 | RECRUITING | PHASE2

40 participants

Efficacy and Safety of AK104 Combined With Chemotherapy and Cetuximab or Bevacizumab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-01-03
Completion:: 2026-01-03

Conditions

Safety

Interventions

DRUG

No Results Yet

NCT07253844 | NOT_YET_RECRUITING | NA

33 participants

Effects of Transverse Abdominis Activation and Rectus Abdominis Strengthening on Inter-rectus Distance and Core Stability

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-11-25
Completion:: 2026-05-25

Conditions

Diastasis Recti Abdominis (DRA)

Interventions

OTHER

No Results Yet