Clinical Trials Updated in 2025

NCT06762457 | COMPLETED | PHASE1

72 participants

A First-in-Human Single and Multiple Ascending Dose Study of MT-501

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-12-11
Completion:: 2025-05-22

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT06754306 | COMPLETED | NA

84 participants

Dynamic Effects of Different Dietary Interventions on Visceral Fat and Biochemical Markers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-08-25
Completion:: 2025-06-09

Conditions

Energy Metabolism

Interventions

OTHER

No Results Yet

NCT06742931 | RECRUITING | NA

1200 participants

Drug-Coated Balloon Versus Drug-Eluting Stent for Treatment of De-Novo Coronary Lesions in Patients With High Bleeding Risk-2

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-04-07
Completion:: 2029-12-31

Conditions

Chronic Coronary Syndrome

Interventions

OTHER

No Results Yet

NCT06731244 | RECRUITING | NA

2400 participants

Shared Decision-making Process for Unprovoked vEnous THromboEmbolism Management. (ETHER )

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-10-30
Completion:: 2035-10-31

Conditions

Venous Thromboembolism

Interventions

OTHER

No Results Yet

NCT06712264 | COMPLETED

18000 participants

Construction and Effectiveness Evaluation of Painless Digestive Endoscopy Mode Led by Anesthesia Nurses Under the Guidance of Anesthesiologists

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-12-01
Completion:: 2025-02-28

Conditions

Pain Management
Endoscopy, Gastrointestinal

No Results Yet

NCT06686017 | ENROLLING_BY_INVITATION

150 participants

Virtuos Bone Graft in Lumbar Fusion

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-06-05
Completion:: 2029-01-31

Conditions

Degenerative Disc Disease

No Results Yet

NCT06668116 | COMPLETED | NA

17 participants

The Impact of Local Anesthetic Dilution on Possible Blinding for Nerve Blocks

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-12-11
Completion:: 2025-10-31

Conditions

Healthy

Interventions

DRUG
OTHER

No Results Yet

NCT06662318 | COMPLETED | NA

75 participants

Perioperative Pain Management for Lumbar Spine Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-10-01
Completion:: 2024-12-30

Conditions

Pain, Postoperative

Interventions

DRUG

No Results Yet

NCT06641115 | RECRUITING | NA

76 participants

Integrated Treatment for Opioid Use Disorder and PTSD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-03-01
Completion:: 2027-08-31

Conditions

Opioid Use Disorder
Posttraumatic Stress Disorder (PTSD)

Interventions

BEHAVIORAL

No Results Yet

NCT06640504 | COMPLETED

30 participants

Serum Albumin Ratios Can Improve Sepsis Mortality Prediction

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-09-30
Completion:: 2024-11-30

Conditions

Sepsis

Interventions

DIAGNOSTIC_TEST
DRUG

No Results Yet

NCT06638294 | RECRUITING

30 participants

Study in Patients With Breast Cancer Leptomeningeal Metastasis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-11-25
Completion:: 2026-12-31

Conditions

Leptomeningeal Metastasis of Breast Cancer

No Results Yet

NCT06638190 | COMPLETED | NA

25 participants

Influence of the Fruit Matrix on Glucose and Insulin Responses After the Intake of Orange Juice in Healthy Human Males

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-10-21
Completion:: 2024-12-20

Conditions

Healthy Nutrition

Interventions

OTHER

No Results Yet

NCT06633692 | COMPLETED | NA

20 participants

Female Pelvic Blood Flow Under Simulated Microgravity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-12-01
Completion:: 2025-05-30

Conditions

Uterine
Ovary
Microgravity
Blood Flow

Interventions

OTHER

No Results Yet

NCT06622902 | RECRUITING | NA

45 participants

Influence of Flow Rate Change on CO2 Levels During High Flow Nasal Ventilation (HFNV) in Preterm Infants.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2023-08-16
Completion:: 2026-12-01

Conditions

Respiratory Distress Syndrome
Prematurity
Non Invasive Ventilation

Interventions

OTHER

No Results Yet

NCT06613841 | RECRUITING | EARLY_PHASE1

15 participants

Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-05-01
Completion:: 2026-10-01

Conditions

Glioblastoma
Recurrent Glioblastoma
Glioblastoma Multiforme of Brain

Interventions

DRUG

No Results Yet

NCT06591468 | ENROLLING_BY_INVITATION | PHASE2/PHASE3

244 participants

A Multicenter, Randomized, Controlled Trial of Prednisone Combined With Ursodeoxycholic Acid in the Treatment of Primary Biliary Cholangitis With Moderate to Severe Interface Hepatitis Characteristics

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-10-30
Completion:: 2027-12-31

Conditions

Primary Biliary Cholangitis (PBC)

Interventions

DRUG

No Results Yet

NCT06590337 | COMPLETED | NA

1202 participants

Radicle Spark for Men 24: A Study of Health and Wellness Products on Sexual Health and Related Health Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-10-07
Completion:: 2025-01-01

Conditions

Sexual Satisfaction
Sexual Function

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06582056 | COMPLETED | NA

226 participants

Study on Biomarkers of Periodontitis and Type 2 Diabetes Mellitus in Males and Females 30 - 70 Years of Age

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-10-09
Completion:: 2025-09-30

Conditions

Periodontal Disease

Interventions

PROCEDURE

No Results Yet

NCT06570109 | ENROLLING_BY_INVITATION

130 participants

Frailty Outcomes And Risk With Alzheimer's Related Dementia

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-08-22
Completion:: 2027-09-01

Conditions

Alzheimer Disease

Interventions

OTHER

No Results Yet

NCT06563622 | COMPLETED | NA

80 participants

Pericapsular Nerve Group Block Versus Caudal Block for Postoperative Pain Management in Pediatric Hip Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-08-10
Completion:: 2025-04-01

Conditions

Pain, Postoperative

Interventions

PROCEDURE

No Results Yet

NCT06559189 | RECRUITING | PHASE1

53 participants

CD19x22 Chimeric Antigen Receptor T-cell Therapy (CAR T) in Pediatric B-ALL

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-09-27
Completion:: 2028-12-31

Conditions

B-cell Acute Lymphoblastic Leukemia

Interventions

BIOLOGICAL

No Results Yet

NCT06548451 | COMPLETED | NA

270 participants

Augmented Reality Assisted Lung Nodule Localization: a Multicentered, Prospective, Randomly Controlled, Non-inferiority Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-08-15
Completion:: 2025-09-30

Conditions

Lung Cancer

Interventions

DEVICE

No Results Yet

NCT06547554 | COMPLETED | PHASE1

60 participants

A DDI Study to Investigate PK and Safety of Cefiderocol in Combination With Xeruborbactam in Healthy Adult Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-09-04
Completion:: 2025-10-27

Conditions

Bacterial Infections

Interventions

DRUG

No Results Yet

NCT06542939 | ENROLLING_BY_INVITATION | NA

450 participants

Scaling Telehealth Models to Improve Co-morbid Diabetes and Hypertension in Immigrant Populations (Phase II)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-11-11
Completion:: 2028-02-01

Conditions

Diabetes Mellitus Type II
Hypertension

Interventions

BEHAVIORAL

No Results Yet

NCT06541106 | RECRUITING

2000 participants

Registry of Endovascular Treatment for Vertebrobasilar Dissecting Aneurysms in China

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2011-01-01
Completion:: 2031-01-01

Conditions

Dissecting Aneurysm of Cerebral Artery

Interventions

OTHER

No Results Yet

NCT06526429 | COMPLETED | NA

25 participants

Local Ischemic Postconditioning in Acute Ischemic Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-10-14
Completion:: 2025-07-04

Conditions

Acute Ischemic Stroke
Mechanical Thrombectomy
Ischemic Postconditioning
Brain Edema
Neuroprotection

Interventions

PROCEDURE

No Results Yet

NCT06519565 | RECRUITING | EARLY_PHASE1

6 participants

Safety and Efficacy of PRG-1801 in Recurrent/Refractory Primary Immune Thrombocytopenia (ITP)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-08-20
Completion:: 2026-12-15

Conditions

Immune Thrombocytopenia

Interventions

DRUG

No Results Yet

NCT06517979 | RECRUITING

10000 participants

Development and Prospective Validation of a Digital Pathology-based Artificial Intelligence Diagnostic Model for Pan-cancer Lymphatic Metastasis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-07-26
Completion:: 2027-06-30

Conditions

Cancer
Lymphatic Metastasis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06517017 | RECRUITING | PHASE2

40 participants

Use of Isatuximab, Dexamethasone and Lenalidomide in a Go-Slow Fashion for Ultra-Frail Patients With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-10-09
Completion:: 2026-11-30

Conditions

Multiple Myeloma
Plasma Cell Leukemia

Interventions

DRUG

No Results Yet

NCT06483802 | WITHDRAWN | PHASE1

0 participants

A Study of ASP2016 in Adults Who Have Heart Disease Associated With Friedreich Ataxia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-11-08
Completion:: 2025-10-22

Conditions

Friedreich Ataxia
Cardiomyopathy

Interventions

GENETIC
DRUG

No Results Yet

NCT06478706 | COMPLETED | PHASE2

57 participants

A Two-Part Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Repeat Doses of Inhaled ETD001 in People With Cystic Fibrosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-06-26
Completion:: 2025-11-14

Conditions

Cystic Fibrosis

Interventions

DRUG

No Results Yet

NCT06472934 | RECRUITING | NA

498 participants

Impact of Beta-blocker on Outcome Among Patients Undergoing Transcatheter Aortic Valve Replacement (B-TAVR)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-07-04
Completion:: 2028-05-31

Conditions

Aortic Stenosis

Interventions

OTHER

No Results Yet

NCT06455527 | RECRUITING | NA

100 participants

Heart Rate Variability (HRV)-Guided Transcranial Direct Current Stimulation (tDCS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-01-02
Completion:: 2027-11-01

Conditions

Depression

Interventions

DEVICE

No Results Yet

NCT06429956 | RECRUITING | NA

93 participants

Combining Treatment Components in Transdiagnostic Therapy for Anxiety and Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-06-28
Completion:: 2026-06-30

Conditions

Depression
Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT06427616 | COMPLETED | NA

51 participants

Moderate Intensity Soleus Pushups Versus Sustained Soleus Pushups on Blood Glucose Level Among Young Population

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-06-06
Completion:: 2025-10-28

Conditions

Health Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT06405607 | RECRUITING | PHASE2

80 participants

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2025-06-12
Completion:: 2028-04-30

Conditions

Alcohol Use Disorder
Alcohol Dependence
Alcohol Abuse

Interventions

DRUG

No Results Yet

NCT06361719 | RECRUITING | NA

262 participants

Efficacy of Two HMOs in Chinese Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-07-29
Completion:: 2026-11-30

Conditions

Healthy Infants

Interventions

OTHER

No Results Yet

NCT06356831 | RECRUITING

300 participants

National Registry of Surgical Treatment and Percutaneous Cryoablation of Parietal Endometriosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-06-15
Completion:: 2027-07-31

Conditions

Endometriosis
Cryotherapy Effect
Surgical
Radiology

No Results Yet

NCT06343974 | RECRUITING

60 participants

Noninvasive Evaluation of Fetal Hyperinsulinemia With Ultrasound Radiomics

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2024-10-11
Completion:: 2026-03-31

Conditions

Pregnancy in Diabetic
Diabetes Mellitus, Type 1

No Results Yet

NCT06330857 | COMPLETED | NA

25 participants

Recurrence and Bowel Function After Laparoscopic Vaginorectopexy, a Modified Anterior Rectopexy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2002-05-28
Completion:: 2024-04-01

Conditions

Rectal Prolapse
Fecal Incontinence
Defecation Disorder
Enterocele
Rectocele

Interventions

PROCEDURE

No Results Yet