Clinical Trials Updated in 2025

NCT04592809 | COMPLETED | PHASE3

50 participants

Ketamine Versus Midazolam for Recurrence of Suicidality in Adolescents

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2022-10-03
Completion:: 2025-07-01

Conditions

Suicide, Attempted
Suicide and Depression
Suicide Threat

Interventions

DRUG

No Results Yet

NCT04584983 | ACTIVE_NOT_RECRUITING | PHASE2

134 participants

Bilirubin Neurotoxicity (BN) and Neurodevelopmental Impairment (NDI) in Extremely Preterm (EP) Infants: Avoidable by Reducing the Usual Intravenous Lipid (UL) Administration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2021-02-11
Completion:: 2024-03-14

Conditions

Bilirubin Encephalopathy

Interventions

DRUG

Results Available

NCT04566991 | RECRUITING | PHASE2

120 participants

Deferoxamine In the Treatment of Aneurysmal Subarachnoid Hemorrhage (aSAH)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2022-03-20
Completion:: 2027-10-31

Conditions

Aneurysmal Subarachnoid Hemorrhage

Interventions

DRUG

No Results Yet

NCT04422613 | COMPLETED | NA

73 participants

Characterization of Persistent Pulmonary Abnormalities Following COVID-19 Pneumonia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2020-05-28
Completion:: 2021-07-01

Conditions

Pneumonia, Viral

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04394975 | COMPLETED | PHASE3

421 participants

Study to Evaluate the Efficacy and Safety of Toripalimab in Combination With Axitinib Versus Sunitinib Monotherapy in Advanced Renal Cell Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2020-08-20
Completion:: 2024-04-02

Conditions

Primary Disease: Unresectable or Metastatic Renal Cell Carcinoma Focus of the Study:PFS Assessed by IRC Per RECIST 1.1

Interventions

COMBINATION_PRODUCT
DRUG

No Results Yet

NCT04394871 | RECRUITING

330 participants

Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2020-12-14
Completion:: 2030-12-25

Conditions

Amyotrophic Lateral Sclerosis Type 4
Inherited Neurological Disorders of RNA Processing

No Results Yet

NCT04392050 | SUSPENDED

90 participants

A Community-Based Educational Intervention to Improve Colorectal Cancer Screening

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2020-01-31
Completion:: 2026-09-25

Conditions

Colorectal Carcinoma

Interventions

OTHER

No Results Yet

NCT04254198 | COMPLETED | NA

241 participants

Tertulias Social Isolation Women's Groups Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2020-07-01
Completion:: 2024-08-30

Conditions

Social Isolation
Depression

Interventions

BEHAVIORAL

Results Available

NCT04232085 | RECRUITING | PHASE2

27 participants

Regenerative Medicine to Restore Hematopoiesis and Immune Function in Immunodeficiencies and Inherited Bone Marrow Failures

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2020-02-12
Completion:: 2027-12-31

Conditions

Primary Immune Deficiency Disorder
Immune Deficiency Disease
Bone Marrow Failure
Short Telomere Length
Fanconi Anemia
Non Fanconi DNA-DSB Repair Disorder
Hoyeraal-Hreidarsson Syndrome
Dyskeratosis Congenita
Telomere Biology Disorder
Short Telomere Syndrome

Interventions

DRUG
RADIATION

No Results Yet

NCT04224142 | COMPLETED

12 participants

Evaluation of PKU Sphere in Maternal PKU

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2019-07-29
Completion:: 2025-10-07

Conditions

Maternal Phenylketonuria

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04151797 | COMPLETED | NA

200 participants

Impact of a Mobile Geriatric Team With a Pharmacist on the Optimisation of Prescriptions in Elderly Inpatients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2019-11-19
Completion:: 2021-03-22

Conditions

Medication Therapy Management

Interventions

OTHER

No Results Yet

NCT04116658 | COMPLETED | PHASE1/PHASE2

100 participants

First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2020-07-13
Completion:: 2024-03-04

Conditions

Glioblastoma, Adult

Interventions

BIOLOGICAL

Results Available

NCT04097860 | COMPLETED | NA

122 participants

Improving Lactation Success in Mothers of Critically Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2020-12-01
Completion:: 2025-09-03

Conditions

Breast Pumping

Interventions

BEHAVIORAL

No Results Yet

NCT04091126 | ACTIVE_NOT_RECRUITING | PHASE1

118 participants

Study of Belantamab Mafodotin Plus Standard of Care (SoC) in Newly Diagnosed Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2019-12-18
Completion:: 2025-06-02

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT04087941 | WITHDRAWN | PHASE2

0 participants

Efficacy and Safety of VM202 in Painful Diabetic Peripheral Neuropathy -The HOPES Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2019-11-30
Completion:: 2022-12-31

Conditions

Painful Diabetic Neuropathy

Interventions

BIOLOGICAL

No Results Yet

NCT03983954 | ACTIVE_NOT_RECRUITING | PHASE1

120 participants

Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumor, Including a Cohort Expansion in Esophageal Cancer.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2019-10-10
Completion:: 2027-03-01

Conditions

ER+ Breast Cancer
Ovarian Cancer
Cervical Squamous Cell Carcinoma
Pancreatic Adenocarcinoma
Endometrial Cancer
Renal Cell Carcinoma
Urothelial Cancer
Head and Neck Squamous Cell Carcinoma
Mesothelioma
Melanoma
Hepatocellular Carcinoma
Prostate Cancer
NSCLC
HER2-negative Breast Cancer
Triple Negative Breast Cancer
Bladder Cancer
Colorectal Cancer Metastatic
GastroEsophageal Cancer
NSCL2 Gene Mutation
Esophageal Cancer

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT03978598 | COMPLETED | PHASE4

150 participants

Breastfeeding Etonogestrel Implant Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2019-06-03
Completion:: 2024-06-04

Conditions

Contraception

Interventions

DRUG
DEVICE

Results Available

NCT03792659 | RECRUITING

800 participants

The EXPLORE MG Registry for Myasthenia Gravis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2016-03-30
Completion:: 2026-09-30

Conditions

Myasthenia Gravis

Interventions

OTHER

No Results Yet

NCT03760003 | COMPLETED | PHASE2

355 participants

Dose-Ranging Phase 2b Study of ABX464 in Moderate to Severe Ulcerative Colitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2019-08-13
Completion:: 2021-04-01

Conditions

Ulcerative Colitis

Interventions

DRUG

Results Available

NCT03730792 | ACTIVE_NOT_RECRUITING | NA

284 participants

Success & Health Impacts For Transit Drivers During Onboarding

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2020-03-22
Completion:: 2024-10-23

Conditions

Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT03707769 | COMPLETED | NA

13 participants

TIPS Microspheres for Perianal Fistula

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2017-03-15
Completion:: 2025-10-31

Conditions

Perianal Fistula

Interventions

DEVICE

No Results Yet

NCT03566238 | COMPLETED | PHASE3

62 participants

This Study Will Investigate the Efficacy and Safety of A4250 in Children With PFIC Types 1 or 2

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2018-05-16
Completion:: 2020-07-27

Conditions

PFIC1
PFIC2

Interventions

DRUG

Results Available

NCT03561077 | COMPLETED | NA

27 participants

Feasibility in France of a Mindfulness-based Group Therapy for Adolescents With Chronic Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2018-05-02
Completion:: 2021-03-31

Conditions

Chronic Pain

Interventions

OTHER

No Results Yet

NCT03542344 | COMPLETED | PHASE1

16 participants

This Study is Done in Healthy Japanese Volunteers. It Looks at How Different Doses of BI 1015550 Are Taken up in the Body and How Well They Are Tolerated.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2018-06-04
Completion:: 2018-08-24

Conditions

Healthy

Interventions

DRUG

Results Available

NCT03537586 | ACTIVE_NOT_RECRUITING | NA

206 participants

A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular Dysfunction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2018-06-29
Completion:: 2025-06-30

Conditions

Coronary Microvascular Disease
Ischemic Heart Disease
Myocardial Ischemia

Interventions

DRUG
DEVICE

No Results Yet

NCT03453723 | COMPLETED | PHASE4

100 participants

Pain Prevention During Propofol Infusion in Pediatric: Hypnoanalgesia of the Hand Versus Lidocaine.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2018-04-18
Completion:: 2019-06-19

Conditions

Pain

Interventions

PROCEDURE
DRUG

No Results Yet

NCT03439943 | COMPLETED | PHASE2

156 participants

Study to Evaluate the Effect of Lixisenatide in Patient With Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2018-06-13
Completion:: 2021-04-15

Conditions

Parkinson Disease

Interventions

DRUG

No Results Yet

NCT03435536 | COMPLETED | NA

35 participants

Surgery Impact on Circulating Tumor DNA in Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2018-02-26
Completion:: 2022-06-20

Conditions

Resectable Pancreatic Cancer

Interventions

OTHER

No Results Yet

NCT03422068 | COMPLETED | PHASE1

15 participants

This Study Tests Different Doses of BI 1015550 in Patients With Idiopathic Pulmonary Fibrosis (IPF). The Study Tests How BI 1015550 is Taken up by the Body and How Well it is Tolerated.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2018-03-16
Completion:: 2019-07-01

Conditions

Idiopathic Pulmonary Fibrosis

Interventions

DRUG

Results Available

NCT03403439 | COMPLETED | PHASE1

16 participants

This Study in Healthy Men Tests How Itraconazole Influences the Amount of BI 1015550 in the Blood

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2018-05-03
Completion:: 2018-07-20

Conditions

Healthy

Interventions

DRUG

Results Available

NCT03382145 | COMPLETED

17956 participants

A Review on the Outcome of Patient Managed in Postmenopausal Bleeding Clinic

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2018-02-01
Completion:: 2025-07-30

Conditions

Postmenopausal Bleeding

Interventions

OTHER

No Results Yet

NCT03302078 | COMPLETED | PHASE1

12 participants

Relative Bioavailability of BI 1015550 Following Oral Administration Under Fed and Fasted Conditions in Healthy Male Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2017-10-16
Completion:: 2017-12-13

Conditions

Healthy

Interventions

DRUG

Results Available

NCT03294408 | COMPLETED | NA

167 participants

Multimodal Imaging of Subchondral Bone in Knee Osteoarthritis : Predictive Model

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2016-11-29
Completion:: 2023-06-19

Conditions

Knee Osteoarthritis
Joint Disease
Arthritis
Musculoskeletal Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03249220 | ACTIVE_NOT_RECRUITING | NA

1 participants

Clinical Pilot Study to Evaluate a New Multi-parameter Neuromonitoring Device in Brain-injured Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2020-09-01
Completion:: 2027-06-30

Conditions

Brain Injuries

Interventions

DEVICE

No Results Yet

NCT03233399 | RECRUITING | NA

30 participants

Modulating Movement Intention Via Cortical Stimulation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2017-07-20
Completion:: 2027-05-31

Conditions

Seizures
Seizure Disorder
Psychogenic Movement Disorder

Interventions

DEVICE

No Results Yet

NCT03230487 | COMPLETED | PHASE1

42 participants

This Study Tests How Healthy Men Tolerate Different Doses of BI1015550. The Study Also Tests How BI 1015550 is Taken up by the Body

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2017-08-10
Completion:: 2018-01-16

Conditions

Healthy

Interventions

DRUG

Results Available

NCT03146156 | COMPLETED | NA

99 participants

Lifestyle Intervention in Preparation for Pregnancy (LIPP)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2017-03-21
Completion:: 2025-08-31

Conditions

Obesity
Lifestyle-related Condition
Macrosomia, Fetal

Interventions

BEHAVIORAL

No Results Yet

NCT03070912 | COMPLETED

257 participants

Frequency of Hemorrhages Associated With the Functional Anomalies of Willebrand Factor in Emergency Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2018-01-19
Completion:: 2023-12-31

Conditions

Von Willebrand Diseases

No Results Yet

NCT03050645 | COMPLETED

210 participants

Metabolic Risk and Life Style Factors in Women With Previous Gestational Diabetes Mellitus (GDM)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-28
Start Date:: 2011-06-30
Completion:: 2017-08-31

Conditions

Type2 Diabetes
Gestational Diabetes
Life Style

No Results Yet

NCT02997605 | COMPLETED | PHASE4

102 participants

Comparison of Two Strategies of Glucocorticoid Withdrawal in Rheumatoid Arthritis Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-28
Start Date:: 2017-01-31
Completion:: 2022-01-27

Conditions

RheumatoId Arthritis

Interventions

DRUG

No Results Yet