Surgery Impact on Circulating Tumor DNA in Pancreatic Cancer
NCT03435536 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 35
Last updated 2025-11-28
Summary
Pancreatic cancer represents the fourth cause of death by cancer in western countries. The only curative treatment is surgery but this one is possible only in 10 to 15 % of cases. To date, there are few biomarkers in circulating blood as prognostic or diagnostic markers in pancreatic cancer. The purpose of this study is to determine if the pancreatic tumor mobilization during its resection impacts the quantity of circulating tumor DNA in peripheral and portal blood.
Conditions
- Resectable Pancreatic Cancer
Interventions
- OTHER
-
Blood samples
Blood samples will be taken to analyze the circulating tumor DNA rate by NGS
Sponsors & Collaborators
-
University Hospital, Toulouse
lead OTHER
Principal Investigators
-
Emmanuel CUELLAR, MD · University Hospital, Toulouse
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-02-26
- Primary Completion
- 2022-06-20
- Completion
- 2022-06-20
Countries
- France
Study Locations
More Related Trials
-
Prognostic and Predictive Biomarkers of Therapeutic Response in Pancreatic Tumors
NCT01692873 ·Status: COMPLETED ·Phase: NA
-
Detection of Circulating Tumor Cells for the Diagnostic of Pancreatic Adenocarcinoma.
NCT02072616 ·Status: TERMINATED ·Phase: NA
-
Liquid Biopsy and Pancreas Cancer: Detection of AXL(+) CTCs (CTC-AXL-PANC)
NCT05346536 ·Status: RECRUITING ·Phase: NA
-
Circulating Cell-free Tumor DNA(ctDNA) in Pancreatic Cancer
NCT02934984 ·Status: UNKNOWN
-
Circulating Tumor Cells in Operative Blood
NCT02150746 ·Status: COMPLETED
-
Prognostic Role of Circulating Tumor DNA in Resectable Pancreatic Cancer
NCT04246203 ·Status: ACTIVE_NOT_RECRUITING
-
Feasibility of Obtaining and Characterizing Circulating Tumorigenic Cells in Patients With Pancreatic Adenocarcinoma
NCT01474564 ·Status: COMPLETED
-
ctDNA Assay in Patients With Resectable Pancreatic Cancer
NCT05052671 ·Status: RECRUITING
-
Identification of Biomarkers Associated With the Presence of Malignant Pancreatic Lesions Compared to Benign Lesions.
NCT06397846 ·Status: RECRUITING ·Phase: NA
-
Diagnostic Accuracy of Circulating Tumor Cells (CTCs) and Onco-exosome Quantification in the Diagnosis of Pancreatic Cancer - PANC-CTC
NCT03032913 ·Status: COMPLETED
-
CIrculating Tumor DNA for Monitoring Response to First Line Chemotherapy in Unresectable PANcreatic Cancer
NCT04560270 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Survival Prognostic Factors for Patients With Exocrine Pancreatic Cancer Resectable or Potentially Resectable
NCT02818907 ·Status: COMPLETED ·Phase: NA
-
Distal Pancreatectomy With Partial Splenectomy for Pancreatic Tumors
NCT01412684 ·Status: WITHDRAWN
-
Early Recurrence After Surgery for Pancreatic Cancer
NCT07241676 ·Status: ENROLLING_BY_INVITATION
-
The Influence of Secretin Stimulated Pancreatic Secretion on ctDNA Expression in Patients With Pancreatic Ductal Adenocarcinoma: The Role of Biomarkers in Determining the Prognosis of Pancreatic Ductal Adenocarcinoma
NCT06807112 ·Status: NOT_YET_RECRUITING
-
Procalcitonin Reveals Early Dehiscence in Pancreatic Surgery: the PREDIPS Study
NCT02756468 ·Status: UNKNOWN
-
Gemcitabine Hydrochloride in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery
NCT01416662 ·Status: COMPLETED ·Phase: PHASE2
-
Prognostic and Predictive Markers of Treatment Response in Patients With PAC.
NCT05776342 ·Status: RECRUITING
-
Selective Plasma Adsorption of Extracellular DNA in Prevention of Intraoperative Metastasis in Pancreatic Cancer (Pilot Study)
NCT06967662 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
The Detection of CTCs in Patients With Pancreatic Cancer Undergoing Cryosurgery Combined With DC-CIK Treatment.
NCT02406846 ·Status: COMPLETED
-
Cancer Stem Cell Specific Aptamer's Ability to Detect Blood Circulating Cancer Stem Cells and Its Role as a Predictor of Prognosis in Pancreatic Cancer
NCT05745415 ·Status: COMPLETED
-
Effect Of Preoperative Chemotherapy On Short-Term Outcome After Pancreatic Resection
NCT01278368 ·Status: COMPLETED ·Phase: NA
-
Influence of Metastatic Sites on Survival Outcomes and Predictive Factors for Extended Survival in Metastatic Pancreatic Cancer a Retrospective Study
NCT07086352 ·Status: NOT_YET_RECRUITING
-
Studying Fibroblast Activity in Patients With Localized Pancreatic Cancer Undergoing Surgery
NCT00900016 ·Status: COMPLETED
-
SERum-bank for PANcreatic Cancer
NCT04374175 ·Status: RECRUITING