Clinical Trials Updated in 2025

NCT07148232 | RECRUITING | PHASE4

150 participants

Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-11-14
Completion:: 2027-06-30

Conditions

Tobacco Cessation
Tobacco Abstinence
Tobacco Use
Tobacco Use Cessation
Tobacco Dependence

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT07145736 | RECRUITING | PHASE4

52000 participants

Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-08-04
Completion:: 2029-03-31

Conditions

Onchocerciasis
Ascaris Lumbricoides Infection
Trichuris Trichiura; Infection
Hookworm Infections
Scabies

Interventions

DRUG

No Results Yet

NCT07145125 | COMPLETED

222 participants

Real-life Efficacy and Toxicity of Brentuximab-Vedotin Associated With Bendamustine in Patients With Relapsed or Refractory Hodgkin Lymphoma (HL-R2-B2)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-02-01
Completion:: 2025-08-21

Conditions

Relapsed or Refractory Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT07141030 | RECRUITING | PHASE1

32 participants

Study of Pharmacokinetics and Safety of GZR18 Injection in Subjects With Renal Impairment and Normal Renal Function

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-04-11
Completion:: 2025-10-09

Conditions

Obesity/Overweight

Interventions

DRUG

No Results Yet

NCT07134387 | RECRUITING

480 participants

Long-Term Burden of BPD and Health-Related Quality of Life (BronQ Family)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-09-16
Completion:: 2026-02-28

Conditions

Bronchopulmonary Dysplasia (BPD)
Chronic Lung Disease of Newborn
HRQOL (Health Related Quality Of Life)

Interventions

OTHER

No Results Yet

NCT07127497 | ACTIVE_NOT_RECRUITING | PHASE2

50 participants

Clinical Study on the Safety and Relationship of Sintilimab Combined With Chemotherapy in Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2022-06-01
Completion:: 2026-10-01

Conditions

Pathological Complete Response
Rectal Cancer
Neoadjuvant Chemoimmunotherapy

Interventions

BIOLOGICAL

No Results Yet

NCT07124156 | NOT_YET_RECRUITING | PHASE1

24 participants

A Challenge Study to Assess the Blood-stage Efficacy of Full-length SUM-101 Malaria Vaccine Candidate

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2026-03-20
Completion:: 2026-07-31

Conditions

Malaria Fever

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT07119450 | COMPLETED | PHASE1

6 participants

The Study of [14C] GZR18

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-05-07
Completion:: 2025-08-13

Conditions

Overweight
Obese
Obesity

Interventions

DRUG

No Results Yet

NCT07118878 | COMPLETED | PHASE1

30 participants

A Multiple Ascending Dose Study With AGMB-129 in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-08-06
Completion:: 2025-09-15

Conditions

Fibrostenotic Crohn's Disease

Interventions

DRUG
OTHER

No Results Yet

NCT07118579 | RECRUITING | PHASE4

114 participants

Effects of Remimazolam and Ciprofol TIVA on PRAE in Pediatric Tonsillectomy and Adenoidectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-09-23
Completion:: 2026-08-31

Conditions

Tonsillectomy With or Without Adenoidectomy

Interventions

DRUG

No Results Yet

NCT07118319 | RECRUITING | PHASE1

12 participants

The Safety, Tolerability and Preliminary Efficacy of Derived Motor Neuron Progenitor Cells (XS228CN) in Subjects With Amyotrophic Lateral Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-09-15
Completion:: 2027-01-31

Conditions

Amyotrophic Lateral Sclerosis (ALS)

Interventions

DRUG

No Results Yet

NCT07102316 | COMPLETED | PHASE1

42 participants

A Study to Assess the Relative Bioavailability After a Single Inhalation Administration of Treprostinil Palmitil Inhalation Powder (TPIP) Formulation 2 (F2) to TPIP Formulation 3 (F3) in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-08-19
Completion:: 2025-10-25

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT07095608 | RECRUITING | NA

80 participants

Defining TRPV4 Contribution of Schwann Cells to Oral Cancer Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-09-01
Completion:: 2029-06-30

Conditions

Oral Cancer
Squamous Cell Carcinoma

Interventions

BEHAVIORAL

No Results Yet

NCT07073248 | RECRUITING | NA

48 participants

Effects of Intermitted Theta Burst Stimulation (iTBS) on Motor Recovery of Upper Extremity in Chronic Stroke Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-11-30
Completion:: 2030-12-31

Conditions

Stroke
Hemiplegia
Hemiparesis After Stroke
Hand Functionality
Chronic Stroke Patients

Interventions

DEVICE

No Results Yet

NCT07070804 | NOT_YET_RECRUITING

600 participants

Maternal Biomarkers and Environmental Contributors to Autism Spectrum Disorders in Children of First-time Mothers

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2026-09-01
Completion:: 2028-08-30

Conditions

Autism

Interventions

OTHER

No Results Yet

NCT07069556 | RECRUITING

12500 participants

ColoSense Post-Approval Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-09-05
Completion:: 2028-09-01

Conditions

Colorectal Cancer (Diagnosis)

Interventions

DEVICE

No Results Yet

NCT07055386 | ACTIVE_NOT_RECRUITING | PHASE2

90 participants

A Study to Compare the Efficacy and Safety of GZR102 Injection and GZR18 Injection in Type 2 Diabetes Mellitus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-08-07
Completion:: 2026-06-28

Conditions

Type 2 Diabetes Mellitus (T2DM)

Interventions

DRUG

No Results Yet

NCT07049952 | RECRUITING | PHASE2/PHASE3

88 participants

BabySTrong II taVNS Feeding Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-11-16
Completion:: 2027-04-01

Conditions

Feeding Delays
Neonates and Term Infants

Interventions

DEVICE
COMBINATION_PRODUCT

No Results Yet

NCT07046403 | COMPLETED | NA

120 participants

Multicentric RCT Comparing High Purity Type I Collagen-Skin Substitute vs dHACM in Treatment of Diabetic Foot Ulcers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-07-05
Completion:: 2025-09-09

Conditions

Diabetic Foot Ulcer (DFU)

Interventions

DEVICE

Results Available

NCT07037589 | RECRUITING

300 participants

Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed?

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-10-13
Completion:: 2026-08-30

Conditions

Hematuria
Acute Cystitis With Hematuria
Bladder Cancer
Urothelial Carcinoma
Renal Cancer

Interventions

PROCEDURE

No Results Yet

NCT07036692 | RECRUITING | NA

120 participants

The FaibaGo Study - Long-Term Weight Reduction Via Low-Threshold Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-10-09
Completion:: 2026-10-31

Conditions

Nutritional and Metabolic Diseases
Overweight

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07030192 | RECRUITING | NA

3181 participants

Peer Support Workers Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-11-23
Completion:: 2027-09-30

Conditions

Substance Use Disorder (SUD)

Interventions

BEHAVIORAL

No Results Yet

NCT07029490 | RECRUITING | NA

2700 participants

Enhancing Mammography Programs for Outreach, Wellness, Education, and Resources (EMPOWER) in Underserved Populations Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-11-19
Completion:: 2028-03-31

Conditions

Breast Cancer

Interventions

OTHER

No Results Yet

NCT06996184 | COMPLETED | PHASE1

28 participants

Effect of Food on the Oral Bioavailability of a Prolonged-release Formulation of Vamifeport in Healthy Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-05-27
Completion:: 2025-07-01

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT06984822 | RECRUITING | NA

150 participants

Evaluation of Serum- and OCT Biomarkers in Patients With DME Treated With Anti-VEGF or Dexamethasone Implant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-08-01
Completion:: 2028-12-31

Conditions

Diabetic Macular Edema
Visual Impairment
Diabetes Mellitus
Hyperglycaemia (Diabetic)
Oxidative Stress
Vascular Endothelial Growth Factor
VEGF

Interventions

DRUG
DEVICE
OTHER

No Results Yet

NCT06965881 | TERMINATED | PHASE1

30 participants

Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-05-08
Completion:: 2025-07-08

Conditions

Tuberous Sclerosis Complex (TSC)
Focal Cortical Dysplasia
Other Neurological Disorders

Interventions

DRUG

No Results Yet

NCT06937957 | RECRUITING | PHASE1

166 participants

A Study of BR111 in Patients With Advanced Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-04-24
Completion:: 2027-10-09

Conditions

Advanced Malignancies

Interventions

DRUG

No Results Yet

NCT06937866 | RECRUITING | PHASE1/PHASE2

38 participants

Maintenance Zanzalintinib With Etoposide After HDCT in GCT

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-11-12
Completion:: 2030-03-31

Conditions

Germ Cell Tumor

Interventions

DRUG

No Results Yet

NCT06930846 | RECRUITING | NA

125 participants

HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-11-03
Completion:: 2028-07-31

Conditions

Brain Cancer
Brain Tumor
Brain Neoplasms
Primary Brain Tumor
Low-grade Glioma
Oligodendroglioma
Meningioma
Low Grade Astrocytoma
Cognitive Dysfunction
Memory Impairment
Memory Disorders
Memory Dysfunction

Interventions

BEHAVIORAL

No Results Yet

NCT06915376 | COMPLETED

30 participants

"AI-Based Noninvasive Blood Pressure Monitoring Compared to Invasive Arterial Measurement"

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-04-07
Completion:: 2025-11-01

Conditions

Blood Pressure Measurement

Interventions

DEVICE

No Results Yet

NCT06910891 | RECRUITING | NA

556 participants

Hemodynamic Evaluation Using Microcirculation for Early Treatment of Septic Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-09-20
Completion:: 2027-03-28

Conditions

Sepsis
Emergency Care
Microcirculation

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06876090 | RECRUITING

200 participants

Sarcopenia in Gestational Diabetes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-05-28
Completion:: 2026-04-30

Conditions

Sarcopenia
Gestational Diabetes Mellitus (GDM)
Pregnancy Complications
Adverse Maternal and Neonatal Outcomes
Cognitive Function

Interventions

DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT06873867 | COMPLETED | NA

104 participants

Treatment of Full-Thickness Wounds: NPWT Combined With Type-I Collagen Based Advanced Skin Substitute Versus NPWT Alone

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-03-15
Completion:: 2025-08-30

Conditions

Full Thickness Skin Defects
Ulcer

Interventions

DEVICE

Results Available

NCT06865326 | RECRUITING

500 participants

Early Detection of CTEPH in Patients After APE

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-03-07
Completion:: 2026-05-31

Conditions

Chronic Pulmonary Thromboembolism

Interventions

OTHER

No Results Yet

NCT06860893 | COMPLETED | PHASE4

30 participants

Spinal Anesthesia for Robotic Assisted Laparoscopic Prostatectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-02-28
Completion:: 2025-09-20

Conditions

Prostate Cancer Surgery

Interventions

DRUG

No Results Yet

NCT06853964 | ACTIVE_NOT_RECRUITING

100 participants

Retrospective Study of AlloMend Acellular Dermal Matrix (ADM) Allograft and Pre-Pectoral Breast Reconstruction

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-01-27
Completion:: 2026-03-31

Conditions

Pre-Pectoral Breast Reconstruction Following Mastectomy

Interventions

OTHER

No Results Yet

NCT06853132 | RECRUITING | NA

110 participants

Baduanjin With Resistance Training Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-08-30
Completion:: 2026-06-30

Conditions

Osteoporosis
Lumbar Disc Herniation

Interventions

BEHAVIORAL

No Results Yet

NCT06845111 | COMPLETED | NA

53 participants

Therapeutic Play and Its Effect on Children's Psychosocial Well-Being

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-05-01
Completion:: 2024-09-01

Conditions

Therapeutic Play
Psychosocial Well-being
Nursing Care

Interventions

OTHER

No Results Yet

NCT06843382 | NOT_YET_RECRUITING

100 participants

Real-world Experience of Oral Agents On Fatigability in Multiple Sclerosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-11-20
Completion:: 2027-06-15

Conditions

Multiple Sclerosis

No Results Yet

NCT06801392 | RECRUITING

50 participants

Left Atrial Posterior Wall and Mitral Isthmus PF Ablation in Non-Paroxysmal AF Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-01-01
Completion:: 2025-12-31

Conditions

Atrial Fibrillation (AF)

Interventions

PROCEDURE

No Results Yet