Clinical Trials Updated in 2025

NCT06496035 | RECRUITING | NA

40 participants

Blood Flow Restriction Training in Patients With Lower Extremity Fractures

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-11-01
Completion:: 2026-05-31

Conditions

Tibial Fractures
Lower Extremity Fracture

Interventions

DEVICE
OTHER

No Results Yet

NCT06492564 | COMPLETED | EARLY_PHASE1

36 participants

Dose, Safety and Pathogenicity of SARS-CoV-2 (COVID-19) Omicron Virus (BA.5)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-12-02
Completion:: 2025-10-16

Conditions

SARS-CoV-2 Infection

Interventions

BIOLOGICAL

No Results Yet

NCT06478641 | AVAILABLE

Expanded Use in Persistent (B. Microti) Babesiosis

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-11-21

Conditions

Persistent Babesiosis

Interventions

DRUG

No Results Yet

NCT06470997 | RECRUITING

60 participants

Specific Biomarkers of Immune-mediated Hepatitis Secondary to Immune Checkpoint Inhibitors

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-07-17
Completion:: 2027-01-18

Conditions

Immune-mediated Hepatitis

Interventions

BIOLOGICAL
PROCEDURE

No Results Yet

NCT06463743 | RECRUITING | PHASE2

30 participants

Metformin as an add-on or Monotherapy in Treatment of Aging People With Multiple Sclerosis (MS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-09-24
Completion:: 2027-01-01

Conditions

Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT06461000 | RECRUITING

1000 participants

EULAR Impact of Rheumatic and Musculoskeletal Diseases Survey

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2025-06-12
Completion:: 2028-06-12

Conditions

Rheumatologic Disease
Musculoskeletal Diseases

Interventions

OTHER

No Results Yet

NCT06449430 | RECRUITING | NA

270 participants

Use of Propofol as a Sedative Agent Versus Spinal Analgesia With Bupivacaine in External Cephalic Version

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-07-06
Completion:: 2027-10-31

Conditions

Pregnancy Complications

Interventions

DRUG

No Results Yet

NCT06447350 | RECRUITING | NA

240 participants

Alcohol Consumption: Norms, Identities, & Motivations

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-04-05
Completion:: 2026-01-30

Conditions

Binge Drinking
Alcohol Drinking

Interventions

BEHAVIORAL

No Results Yet

NCT06427564 | RECRUITING

3000 participants

Vital Signs Collection Via "Comestai" App

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-06-01
Completion:: 2025-12-01

Conditions

Vital Signs

No Results Yet

NCT06427122 | COMPLETED | NA

96 participants

Effect of EMD Protocol for Urge on Dermatology-specific Quality of Life

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-03-11
Completion:: 2025-09-15

Conditions

Atopic Dermatitis
Prurigo Nodularis

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06421025 | RECRUITING

160 participants

Blood Viscosity in Polycythemia Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-09-10
Completion:: 2031-09-10

Conditions

Polycythemia Secondary
Polycythemia, Primary

No Results Yet

NCT06388902 | SUSPENDED | PHASE1

120 participants

A Phase I Study of BR115 for Injection Alone in Subjects With Advanced Solid Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-02-19
Completion:: 2028-08-31

Conditions

Advanced Solid Malignancies

Interventions

DRUG

No Results Yet

NCT06381037 | RECRUITING | NA

110 participants

Quality of Life and Psychological Strengths of Older People

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2023-09-01
Completion:: 2026-01-31

Conditions

Quality of Life
Skills, Coping

Interventions

BEHAVIORAL

No Results Yet

NCT06378138 | RECRUITING | PHASE2/PHASE3

226 participants

ICP-248 in Combination With Orelabrutinib in Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (APEX-03)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-05-15
Completion:: 2030-11-25

Conditions

Hematologic Malignancies

Interventions

DRUG

No Results Yet

NCT06377605 | COMPLETED | NA

60 participants

The Efficacy of Thoracic Erector Spinae Plane Block For Perioperative Analgesia in Laparoscopic Bariatric Surgery for Super Obese Patients.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-03-10
Completion:: 2025-05-30

Conditions

Erector Spinae Plane Block
Super Obese Patients
Bariatric Surgery

Interventions

PROCEDURE
DRUG

No Results Yet

NCT06352775 | ACTIVE_NOT_RECRUITING | NA

250 participants

Calcium Carbonate on Labor Induction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-06-01
Completion:: 2026-12-30

Conditions

Pregnancy
Uterine Contraction

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06352437 | COMPLETED | PHASE1

125 participants

A Study to Test How Well Different Doses of BI 3034701 Are Tolerated by Healthy Men and People With Overweight or Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-06-10
Completion:: 2025-10-07

Conditions

Healthy

Interventions

DRUG

No Results Yet

NCT06352294 | COMPLETED | NA

45 participants

Examining The Effects of Core Stabilization Exercises and Myofascial Release Technique in Individuals With Chronic Neck Pain: A Randomized Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-04-02
Completion:: 2024-06-14

Conditions

Neck Pain

Interventions

OTHER

No Results Yet

NCT06344949 | COMPLETED | PHASE4

100 participants

Ciprofol Versus Propofol for Tracheal Intubation in ICU

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-11-14
Completion:: 2025-10-13

Conditions

Emergency Tracheal Intubation in Critically Ill Patients

Interventions

DRUG

No Results Yet

NCT06343779 | COMPLETED | PHASE3

134 participants

Study of Oral Deucrictibant Soft Capsule for On-Demand Treatment of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-02-26
Completion:: 2025-10-17

Conditions

Hereditary Angioedema
Hereditary Angioedema Type I
Hereditary Angioedema Type II
Hereditary Angioedema Types I and II
Hereditary Angioedema Attack
Hereditary Angioedema With C1 Esterase Inhibitor Deficiency
Hereditary Angioedema - Type 1
Hereditary Angioedema - Type 2
C1 Esterase Inhibitor [C1-INH] Deficiency
C1 Esterase Inhibitor Deficiency
C1 Esterase Inhibitor, Deficiency of
C1 Inhibitor Deficiency
Hereditary Angioedema - Type 3
Hereditary Angioedema Type III

Interventions

DRUG

No Results Yet

NCT06342973 | COMPLETED | PHASE4

15 participants

Horizontal Ridge Augmentation With Demineralized Bone Allograft Layered With Xenograft - a Prospective Clinical Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-03-27
Completion:: 2025-10-15

Conditions

Alveolar Ridge Deficiency

Interventions

DEVICE

No Results Yet

NCT06323850 | COMPLETED | NA

13 participants

Improving Access to Community-Based Occupations Via a Rideshare Training Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-05-06
Completion:: 2024-11-11

Conditions

Autism

Interventions

BEHAVIORAL

No Results Yet

NCT06322888 | RECRUITING | NA

46 participants

Resistance and Aerobic Exercise for Prevention in Women With Dense Breasts (REP-D)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-03-28
Completion:: 2026-09-30

Conditions

Breast Cancer
Breast Cancer Female

Interventions

BEHAVIORAL

No Results Yet

NCT06320080 | TERMINATED | PHASE1

22 participants

Clinical Study of TQB2223 Injection Combined With AK105 Injection in the Treatment of Advanced Hepatocellular Carcinoma.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-05-30
Completion:: 2025-11-03

Conditions

Advanced Hepatocellular Carcinoma

Interventions

DRUG

No Results Yet

NCT06320002 | COMPLETED | NA

25 participants

Communication Intervention for Fecal Ostomy Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-06-13
Completion:: 2025-04-30

Conditions

Surgery
Colostomy Stoma
Ileostomy - Stoma

Interventions

BEHAVIORAL

No Results Yet

NCT06314295 | RECRUITING

1500 participants

Automated Echocardiographic Detection of Coronary Artery Disease Using Artificial Intelligence Methods

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-03-11
Completion:: 2026-03-11

Conditions

Coronary Artery Disease

No Results Yet

NCT06313801 | RECRUITING | PHASE2

106 participants

Comparing the Safety and Efficacy of First-line Polychemotherapy and Polychemotherapy in Combination With PIPAC Sessions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2023-01-19
Completion:: 2026-07-01

Conditions

Gastric Cancer

Interventions

DRUG
PROCEDURE
COMBINATION_PRODUCT

No Results Yet

NCT06313216 | COMPLETED | NA

63 participants

Treatment of Peri-implant Bone Dehiscence Using Autogenous Tooth Plate

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-03-15
Completion:: 2025-10-30

Conditions

Implant Complication
Peri-Implantitis
Periodontal Diseases

Interventions

PROCEDURE

No Results Yet

NCT06309316 | RECRUITING | NA

220 participants

The Impact of Person Centred Care (PCC) in Grave's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-03-25
Completion:: 2029-02-25

Conditions

Graves Disease

Interventions

BEHAVIORAL

No Results Yet

NCT06289894 | TERMINATED | PHASE1

13 participants

A Study of BRY805 in Participants With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-03-13
Completion:: 2025-05-16

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT06287853 | SUSPENDED

170 participants

Tapestry Rotator Cuff Repair PMCF

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2026-12-28
Completion:: 2030-12-30

Conditions

Rotator Cuff Tears
Rotator Cuff Injuries

Interventions

DEVICE

No Results Yet

NCT06272669 | RECRUITING | NA

90 participants

Cumulative and Booster Effects of Multisession Prefrontal tDCS in ASD Adolescents

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2022-06-02
Completion:: 2026-09-30

Conditions

Transcranial Direct Current Stimulation
Autistic Spectrum Disorder
Electroencephalography

Interventions

DEVICE

No Results Yet

NCT06271655 | ACTIVE_NOT_RECRUITING | NA

200 participants

Rapid Diagnosis of Viral Acute Respiratory Infection to Decrease Unnecessary Antibiotic Utilization in the Emergency Department (RADIATE)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-03-12
Completion:: 2025-09-20

Conditions

Acute Respiratory Infection
Viral Infection
Upper Respiratory Tract Infections

Interventions

DEVICE

No Results Yet

NCT06254482 | ACTIVE_NOT_RECRUITING | PHASE2

144 participants

An Extension Study to Evaluate the Long-Term Safety and Efficacy of Votoplam in Participants With Huntington's Disease (HD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2023-08-25
Completion:: 2029-07-16

Conditions

Huntington Disease

Interventions

DRUG

No Results Yet

NCT06252701 | COMPLETED | NA

20 participants

Diet and Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-06-18
Completion:: 2025-06-18

Conditions

Depression
Major Depressive Disorder
Weight Gain
Obesity
Metabolic Syndrome

Interventions

BEHAVIORAL

No Results Yet

NCT06249451 | COMPLETED | NA

124 participants

Staphylococcus Aureus Bacteraemia (SAB)-Support-Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-01-22
Completion:: 2024-11-19

Conditions

Staphylococcus Aureus Bacteremia

Interventions

OTHER

No Results Yet

NCT06235775 | COMPLETED | PHASE2

67 participants

Administration of GV1001 for the Treatment of Progressive Supranuclear Palsy Who Completed Study GV1001-PSP-CL2-011

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2023-12-12
Completion:: 2025-09-01

Conditions

Progressive Supranuclear Palsy

Interventions

DRUG

No Results Yet

NCT06233383 | COMPLETED

80 participants

Developing Screening Clinical Breast Examination Implementation Strategies in South Africa

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-06-01
Completion:: 2025-04-01

Conditions

Breast Cancer

No Results Yet

NCT06232408 | TERMINATED | PHASE1

29 participants

LIONS (PLK4 Inhibitor in Advanced Solid Tumors)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-02-14
Completion:: 2025-08-27

Conditions

Advanced Solid Tumor

Interventions

DRUG

Results Available

NCT06220760 | COMPLETED

154 participants

Outcomes of Placenta Accreta Spectrum Disorders Surgery in Relation to Placenta Accreta Scoring Index

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-21
Start Date:: 2024-02-20
Completion:: 2024-12-30

Conditions

Placenta Previa
Placenta Accreta

Interventions

DIAGNOSTIC_TEST

No Results Yet