Clinical Trials Updated in 2025

NCT06988332 | COMPLETED | NA

56 participants

Problem Management Plus (PM+) in Chile: a Pilot Randomized Controlled Trial of a Psychological Transdiagnostic Intervention Delivered in Primary Health Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-05-09
Completion:: 2025-09-12

Conditions

Anxiety Disorders
Depressive Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06983678 | RECRUITING | NA

132 participants

Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Without Chronic Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-11-04
Completion:: 2030-03-31

Conditions

Tobacco Use
Chronic Pain

Interventions

BEHAVIORAL

No Results Yet

NCT06981104 | COMPLETED | NA

60 participants

Tear Film Stability and Improvement of Asthenopia: Efficacy Observation of 0.05% Cyclosporine in Dry Eye Patients With Short BUT

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2024-11-18
Completion:: 2025-02-14

Conditions

Dry Eye Disease (DED)
Asthenopia

Interventions

DRUG

No Results Yet

NCT06956040 | RECRUITING | NA

500 participants

Involvement of General Practitioners in Lung Cancer Screening

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-06-02
Completion:: 2027-12-31

Conditions

Lung Cancer

Interventions

PROCEDURE

No Results Yet

NCT06954610 | RECRUITING

500 participants

Cardiac Assessment for Recurrent Stroke Risk Evaluation in Atrial Fibrillation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-11-04
Completion:: 2028-06-30

Conditions

Ischemic Stroke
Atrial Fibrillation
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Vascular Diseases
Arrhythmias, Cardiac
Heart Diseases
Brain Infarction
Brain Ischemia
Infarction Cerebral
Stroke
Cardioembolic Stroke
Ischemia

Interventions

OTHER

No Results Yet

NCT06952452 | RECRUITING | PHASE3

630 participants

Pharmacogenomics of antiVEGF in Patients With Age-Associated Macular Degeneration (AMD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2022-11-18
Completion:: 2026-07-31

Conditions

Wet Age-related Macular Degeneration

Interventions

DRUG

No Results Yet

NCT06949631 | COMPLETED | NA

74 participants

Study on the Effects of Resistant Potato Starch on Gut Bacteria in Healthy Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-05-29
Completion:: 2025-10-03

Conditions

Gastrointestinal Microbiota

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT06942325 | WITHDRAWN | NA

0 participants

Performance and Effectiveness of a Self-fitting Over-the-counter Hearing Aid

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-09-01
Completion:: 2025-12-31

Conditions

Hearing Loss
Hearing Impairment

Interventions

DEVICE

No Results Yet

NCT06940947 | RECRUITING | PHASE3

434 participants

Endoscopic Therapy Or Surgery for Early Colon Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-08-25
Completion:: 2033-09-01

Conditions

Colon Cancer

Interventions

PROCEDURE

No Results Yet

NCT06938269 | RECRUITING | PHASE1

60 participants

A Study to Evaluate MWN109 Tablets in Healthy Adult Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-06-18
Completion:: 2026-03-31

Conditions

Overweight or Obesity

Interventions

DRUG

No Results Yet

NCT06937749 | RECRUITING | PHASE2

165 participants

A Study of IBI362 in Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-07-01
Completion:: 2026-04-30

Conditions

Metabolic Dysfunction-associated Steatohepatitis (MASH)

Interventions

DRUG

No Results Yet

NCT06927141 | COMPLETED | NA

27 participants

Effect of Flexible Catheter Materials on Catheter Angle and Blood Vessel Irritation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-05-26
Completion:: 2025-09-08

Conditions

Healthy
Intravenous Catheterization
Oedema
Thrombosis

Interventions

DEVICE

No Results Yet

NCT06918613 | COMPLETED

36 participants

Ultrasonographic Evaluation of the Effects of Different Wrist Positions on the Median Nerve in Patients With Generalized Joint Hypermobility

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-20
Start Date:: 2024-02-01
Completion:: 2025-05-15

Conditions

Hypermobility Syndrome (Disorder)
Ultrasonography
Median Nerve

No Results Yet

NCT06905873 | RECRUITING | PHASE1

64 participants

A Study to Evaluate the Safety and Efficacy of FB102 in Patients With Non-segmental Vitiligo

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-03-25
Completion:: 2026-12-31

Conditions

Vitiligo

Interventions

DRUG

No Results Yet

NCT06891573 | RECRUITING | NA

40 participants

South Korean Study to Prevent Frailty and Aging-related Diseases Through Lifestyle Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-02-26
Completion:: 2025-12-20

Conditions

Frailty

Interventions

BEHAVIORAL

No Results Yet

NCT06878300 | WITHDRAWN | NA

0 participants

Assessing Functional Outcomes and User Experience of the Lexie B3 Pro Powered by Bose Over-the-counter Self-Fitting Hearing Aid

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-07-01
Completion:: 2025-08-31

Conditions

Hearing Loss
Self Perceived Hearing Loss
Hearing Impairment

Interventions

DEVICE

No Results Yet

NCT06873256 | COMPLETED

310 participants

Evaluation of the Hospital Pathway for Frail Elderly Patients Hospitalised for Pathologies Leading to Medical Decompensation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-02-28
Completion:: 2025-07-24

Conditions

Frail Elderly People Hospitalized

No Results Yet

NCT06864468 | RECRUITING | NA

120 participants

Primary Prevention of Obesity in American Indian Youth in Rural Tribal Schools

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-08-26
Completion:: 2027-05-31

Conditions

Obesity Prevention
School Wellness Policy

Interventions

BEHAVIORAL

No Results Yet

NCT06856252 | RECRUITING | NA

60 participants

Human Liver ORganoids as a Model to Study the Development of Non-Alcoholic SteatOhepatitis (NASH)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2021-07-01
Completion:: 2030-07-31

Conditions

NAFLD

Interventions

GENETIC

No Results Yet

NCT06855602 | RECRUITING | NA

15 participants

CHM for Female Stress Urinary Incontinence

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2024-10-21
Completion:: 2026-03-15

Conditions

Stress Urinary Incontinence (SUI)

Interventions

DRUG

No Results Yet

NCT06851195 | ENROLLING_BY_INVITATION | NA

40 participants

Effect of Neuromuscular Electrical Stimulation of Lower Limbs on Improving Exercise Self-Efficacy, Dyspnea During Activity and Fatigue in Patients With Chronic Obstructive Pulmonary Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-02-25
Completion:: 2026-12-31

Conditions

Chronic Obstructive Pulmonary Disease (COPD)
Neuromuscular Electrical Stimulation (NMES)
Exercise Self-Efficacy
Dyspnea During Activity
Fatigue

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT06830382 | RECRUITING

70 participants

HER2-PET as a Precision Imaging Tool for Treatment With HER2-ADC in HER2-expressing mBC

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-10-03
Completion:: 2030-04-01

Conditions

Breast Cancer Stage IV
HER2-low Breast Cancer
Molecular Imaging

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06828653 | RECRUITING | NA

50 participants

Comparing Digitally and Traditionally Made Ankle Foot Orthoses

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-09-05
Completion:: 2026-12-31

Conditions

Flaccid Paresis
Spastic Paresis
Cerebral Palsy
Stroke
Spinal Cord Injury
Spina Bifida
Traumatic Peripheral Nerve Injury

Interventions

DEVICE

No Results Yet

NCT06822946 | RECRUITING | PHASE2

192 participants

Zhibitai Capsules for the Treatment of Primary Hyperlipidemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-03-27
Completion:: 2026-02-28

Conditions

Primary Hyperlipidemia

Interventions

DRUG

No Results Yet

NCT06817252 | RECRUITING | NA

60 participants

How a Mediterranean Diet With Potatoes Impacts Heart and Metabolic Health in Adults With Pre-Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-04-24
Completion:: 2026-10-31

Conditions

Prediabetes
Lipid Profile
Hypertension
Glycemic Control
Arterial Stiffness, Blood Pressure
Inflammation Biomarkers
Dietary Quality
Body Composition Measurement
Waist Circumference
Anthropometrics: Height and Weight

Interventions

BEHAVIORAL

No Results Yet

NCT06800404 | ACTIVE_NOT_RECRUITING | PHASE2

10 participants

"HB-adMSCs for the Treatment of Patients With Multiple Sclerosis"

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-05-02
Completion:: 2027-01-31

Conditions

Relapsing Remitting Multiple Sclerosis (RRMS)
Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT06778681 | COMPLETED | NA

37 participants

Mechanism of Fatigue in Fibromyalgia and Cortical Motor Neuron Dysfunction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2024-04-18
Completion:: 2025-05-15

Conditions

Fibromyalgia

Interventions

OTHER

No Results Yet

NCT06774235 | RECRUITING | PHASE3

326 participants

Prevention of Secondary Infections by Interferon Gamma in ICU-acquired Sustained Immune-suppression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-07-09
Completion:: 2028-10-09

Conditions

Sustained Immunosuppression

Interventions

DRUG

No Results Yet

NCT06769945 | COMPLETED | NA

56 participants

Kolcaba's Comfort Theory on the Comfort Levels of Patients Undergoing Open Heart Valve Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2024-10-09
Completion:: 2025-04-09

Conditions

Surgery (Cardiac)

Interventions

BEHAVIORAL

No Results Yet

NCT06768320 | WITHDRAWN | PHASE4

0 participants

Treating Toddler Obesity by Treating the Parent/Caregiver Obesity With Weight Loss Medications

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-12-31
Completion:: 2027-01-31

Conditions

Weight Loss
Obesity, Childhood
Obesity

Interventions

DRUG

No Results Yet

NCT06752122 | RECRUITING | PHASE1

24 participants

Safety, Tolerability, and Pharmacokinetics of RCS-21 in Healthy Volunteers.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-02-18
Completion:: 2026-06-30

Conditions

Healthy Volunteers
Safety
Tolerability
Pharmacokinetics

Interventions

DRUG

No Results Yet

NCT06741358 | RECRUITING | PHASE4

30 participants

Using Glialia for Treating Persistent Perceptual Postural Dizziness

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2024-12-21
Completion:: 2025-10-10

Conditions

Persistent Postural Perceptual Dizziness

Interventions

OTHER

No Results Yet

NCT06730841 | COMPLETED | NA

3 participants

Dose-Optimized and Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2024-09-26
Completion:: 2025-08-01

Conditions

Treatment Resistant Depression
Major Depressive Disorder

Interventions

DEVICE

No Results Yet

NCT06714526 | RECRUITING | NA

100 participants

Effect of Genotype-Guided Oral P2Y12 Inhibitor Selection vs Conventional Clopidogrel Therapy in Symptomatic ICAD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-10-07
Completion:: 2027-08-31

Conditions

Intracranial Atherosclerosis

Interventions

GENETIC
DRUG

No Results Yet

NCT06710808 | COMPLETED | NA

4 participants

VIRTUAL WALKING AND TRANSCRANIAL DIRECT CURRENT STIMULATION FOR CHRONIC NEUROPATHIC PAIN DUE TO SPINAL CORD INJURY

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2024-10-01
Completion:: 2025-04-01

Conditions

Spinal Cord Injury
Chronic Neuropathic Pain

Interventions

OTHER

No Results Yet

NCT06707259 | RECRUITING | PHASE1

24 participants

Clinical Study of Cord Blood-derived IL-10/IL-15 CD19-CAR NK in the Treatment of Refractory/Relapsed B-cell NHL

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2024-12-01
Completion:: 2026-12-01

Conditions

B-cell Non Hodgkin Lymphoma

Interventions

BIOLOGICAL

No Results Yet

NCT06702241 | RECRUITING | PHASE2/PHASE3

116 participants

Newborn Jaundice - An Investigation of Different Approaches to Light Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-01-14
Completion:: 2027-11-01

Conditions

Neonatal Hyperbilirubinemia

Interventions

OTHER

No Results Yet

NCT06700707 | COMPLETED

120 participants

Turkish Adaptation, Validity and Reliability Study of the Athlete Disability Index Questionnaire

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-02-27
Completion:: 2025-06-02

Conditions

Low Back Pain
Disability
Athlete
Sport

Interventions

OTHER

No Results Yet

NCT06689839 | RECRUITING | NA

500 participants

Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-20
Start Date:: 2025-09-09
Completion:: 2026-12-31

Conditions

Aortic Stenosis Treated With TAVI
Aortic Diseases

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT06683625 | COMPLETED

27 participants

Neurotransmitter Analysis, Stress, and Energy Availability in Athletes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-20
Start Date:: 2024-11-10
Completion:: 2024-11-10

Conditions

Healthy

Interventions

DIAGNOSTIC_TEST

No Results Yet