Clinical Trials Updated in 2025

NCT06976047 | COMPLETED | NA

100 participants

Sensory Distraction Tools on Anxiety Management in Pediatric Dental Patient

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-12-15
Completion:: 2025-07-22

Conditions

Anaesthesia
Anxiety
Children

Interventions

BEHAVIORAL

No Results Yet

NCT06974851 | RECRUITING | PHASE3

140 participants

A Phase III Study Evaluating the Efficacy and Safety of HRS9531 Injection in Subjects With Obstructive Sleep Apnea (OSA) and Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-07-25
Completion:: 2026-12-31

Conditions

Bstructive Sleep Apnea (OSA) and Obesity

Interventions

DRUG

No Results Yet

NCT06971874 | RECRUITING

356 participants

The Outcome of Chronic Kidney Disease Patients With Obstructive Sleep Apnea Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-07-17
Completion:: 2029-06-30

Conditions

Chronic Kidney Diseases
OSAS (Obstructive Sleep Apneas Syndrome)

Interventions

OTHER

No Results Yet

NCT06970028 | RECRUITING

150 participants

Somatosensory Phenotyping of ADPKD

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-09-09
Completion:: 2026-12-31

Conditions

ADPKD
Pain

Interventions

OTHER

No Results Yet

NCT06968468 | NOT_YET_RECRUITING | NA

20 participants

Resiliency Intervention for Patients With ALS and Their Care-Partners

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2026-05-13
Completion:: 2027-02-13

Conditions

Amyotrophic Lateral Sclerosis (ALS)
Emotional Distress

Interventions

BEHAVIORAL

No Results Yet

NCT06962787 | RECRUITING | PHASE2

260 participants

A Study of BL-B01D1+TKI±Pembrolizumab in Patients With Locally Advanced or Metastatic Renal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-07-28
Completion:: 2027-05-31

Conditions

Renal Cancer

Interventions

DRUG

No Results Yet

NCT06961253 | ACTIVE_NOT_RECRUITING

3500 participants

External Validation of Ten Prediction Models for 30-day Mortality Following Hip Fracture

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-06-01
Completion:: 2025-12-31

Conditions

Hip Fracture
Hip Fracture Surgeries

No Results Yet

NCT06958718 | COMPLETED | PHASE4

52 participants

Ultrasound vs. Surgical ESP Block With Bupivacaine-Dexmedetomidine in Lumbar Fusion Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-05-06
Completion:: 2025-08-31

Conditions

Post Operative Pain

Interventions

PROCEDURE
DRUG

No Results Yet

NCT06957587 | RECRUITING

800 participants

A Deep Learning Model for Blood Volume Estimation From Multi-modal Ultrasound

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-10-01
Completion:: 2027-07-31

Conditions

Blood Volume Analysis
Ultrasound
Machine Learning

No Results Yet

NCT06955481 | RECRUITING

120 participants

Study to Evaluate the Performance of Navigated TKA With OrthoPilot® pheno4u TKA Level 1

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-10-07
Completion:: 2027-07-31

Conditions

Osteoarthritis, Knee
Joint Diseases
Rheumatoid Arthritis of Knee
Posttraumatic Arthropathy

Interventions

PROCEDURE

No Results Yet

NCT06949059 | RECRUITING | PHASE1/PHASE2

30 participants

Intravenous Hydromorphone for the Treatment of Acute Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-01-01
Completion:: 2026-12-31

Conditions

Acute Chest Pain

Interventions

DRUG

No Results Yet

NCT06937619 | COMPLETED | PHASE1

263 participants

A Study to Assess the Relative Bioavailability of Risankizumab Following Subcutaneous Administration With On-Body Injector in Healthy Adult Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-04-21
Completion:: 2025-11-10

Conditions

Healthy Volunteer

Interventions

DRUG

No Results Yet

NCT06937138 | RECRUITING | NA

334 participants

Artificial Intelligence-Assisted vs Surgeon-Planned Trajectories in Freehand Femoral Neck Screw Fixation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-11-14
Completion:: 2027-04-15

Conditions

Femoral Neck Fractures

Interventions

PROCEDURE

No Results Yet

NCT06934408 | RECRUITING | PHASE1

92 participants

A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-5817 Injection

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-05-08
Completion:: 2027-04-30

Conditions

Obesity
Overweight

Interventions

DRUG

No Results Yet

NCT06927882 | NOT_YET_RECRUITING | NA

180 participants

Effects of Whole Body Vibration Therapy on Cognitive Function, Balance, and Quality of Life in Older Adults With Mild Cognitive Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-11-15
Completion:: 2025-12-30

Conditions

Cognitive Impairment
Balance
Quality of Life

Interventions

OTHER

No Results Yet

NCT06925113 | COMPLETED

509 participants

A Study to Investigate the Prevalence of Human Epidermal Growth Factor Receptor 2 (HER2) Immunohistochemistry (IHC) 3+ and Characterize the Clinicopathologic Features of Gynecologic Cancers in Taiwan

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-01-31
Completion:: 2025-08-31

Conditions

Cervical Cancers
Endometrial Cancer
Ovarian Cancer

No Results Yet

NCT06912074 | RECRUITING | PHASE2

134 participants

Hypofractionated vs. Conventional Chemoradiotherapy After Induction Chemo-immunotherapy for Unresectable Esophageal Squamous Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-04-05
Completion:: 2029-04-04

Conditions

Esophageal Squamous Cell Carcinoma (ESCC)

Interventions

DRUG
RADIATION

No Results Yet

NCT06908707 | COMPLETED | PHASE1

32 participants

A Study to Investigate Safety, Tolerability and Pharmacokinetics of LAE102 in Postmenopausal Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-04-22
Completion:: 2025-10-23

Conditions

Postmenopausal
Healthy Adult Female Participants

Interventions

DRUG

No Results Yet

NCT06906458 | COMPLETED

120 participants

Impact of Paresthesia on Postoperative Neurological Symptoms

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-04-11
Completion:: 2025-09-15

Conditions

Interscalene Block
Postoperative Pain

Interventions

OTHER

No Results Yet

NCT06883279 | COMPLETED | NA

85 participants

Effect of Interscalene Block Methods on Rebound Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-03-20
Completion:: 2025-09-10

Conditions

Anesthesia
Pain, Shoulder
Pain, Postoperative

Interventions

OTHER

No Results Yet

NCT06881693 | RECRUITING | NA

60 participants

Internet-Delivered Cognitive Behaviour Therapy for Depression and Anxiety in Perinatal Parents

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-02-24
Completion:: 2026-06-30

Conditions

Anxiety
Depression

Interventions

BEHAVIORAL

No Results Yet

NCT06873191 | NOT_YET_RECRUITING

600 participants

A Study to Learn More About Tukysa Once it is Out in the Korean Market

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2027-01-01
Completion:: 2029-05-01

Conditions

HER2-positive Locally Advanced Unresectable
Metastatic Breast Cancer

No Results Yet

NCT06869876 | COMPLETED

75 participants

Ortopod CZ Pilot Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-03-01
Completion:: 2025-10-22

Conditions

Postoperative Delirium (POD)
Perioperative Neurocognitive Disorders

No Results Yet

NCT06848699 | RECRUITING | PHASE1/PHASE2

105 participants

A Phase Ib/II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Patients With Advanced/Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-02-25
Completion:: 2026-10-30

Conditions

Solid Tumor Cancer
Non Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06846866 | COMPLETED | PHASE1

74 participants

A Study to Investigate the Safety, Tolerability, and Drug Levels of BMS-986419 (Part 1) and the Effects Multiple Doses of BMS-986419 on Cardiac Repolarization (Part 2) in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-02-27
Completion:: 2025-10-21

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT06834789 | COMPLETED | PHASE1

132 participants

A Study to Assess the Adverse Events of Intramuscular Injections of AGN-151586 and OnabotulinumtoxinA in Adult Participants for the Change of Glabellar Lines (GL)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-02-18
Completion:: 2025-11-03

Conditions

Glabellar Lines

Interventions

DRUG

No Results Yet

NCT06832540 | COMPLETED | PHASE1

6 participants

Mass Balance Study of [14C] TJ0113 in Healthy Chinese Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-02-19
Completion:: 2025-03-05

Conditions

Healthy Chinese Subjects

Interventions

DRUG

No Results Yet

NCT06824753 | COMPLETED | NA

60 participants

Postoperative Use Of Pump Blood İn Cardiopulmonary Bypass Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-04-01
Completion:: 2024-04-01

Conditions

Cardio-pulmonary Bypass

Interventions

OTHER

No Results Yet

NCT06822127 | RECRUITING | NA

30 participants

Simulation of Facial Soft Tissue in Orthognathic Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-04-28
Completion:: 2027-10-31

Conditions

Orthognathic Surgery

Interventions

OTHER

No Results Yet

NCT06821685 | RECRUITING | PHASE1

14 participants

Autologous Decidual-like Natural Killer Cells Therapy for Infertility or Adverse Pregnancy History

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-02-13
Completion:: 2027-07-31

Conditions

Abortion, Habitual
Infertility Unexplained
Embryo Implantation
Pre-Eclampsia

Interventions

BIOLOGICAL

No Results Yet

NCT06816264 | COMPLETED | PHASE2

120 participants

A Study of HRS-5346 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-02-18
Completion:: 2025-09-29

Conditions

Treatment of Lipoprotein Disorder

Interventions

DRUG

No Results Yet

NCT06807411 | COMPLETED | NA

30 participants

Effectiveness of Video-Based Upper Extremity Exercise Program in Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-02-03
Completion:: 2025-07-05

Conditions

Parkinson Disease
Exercise
Exergame
Therapy

Interventions

OTHER

No Results Yet

NCT06799234 | ACTIVE_NOT_RECRUITING | PHASE2

240 participants

Safety and Immunogenicity of a Candidate Rift Valley Fever Vaccine (RVF003)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-07-08
Completion:: 2026-03-31

Conditions

Rift Valley Fever

Interventions

BIOLOGICAL

No Results Yet

NCT06795724 | COMPLETED | NA

60 participants

Effect of Peng Block Application on Inflammation and Mortality in Hip Fractures

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-01-30
Completion:: 2025-07-17

Conditions

Inflammatory Response
Anesthesia
Hip Fractures

Interventions

OTHER

No Results Yet

NCT06793033 | RECRUITING | NA

84 participants

A Randomized Controlled Study of the NEURESCUE Device as an Adjunct to Advanced Cardiac Life Support

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-07-07
Completion:: 2027-01-31

Conditions

Cardiac Arrest (CA)
Cardiopulmonary Arrest

Interventions

PROCEDURE
DEVICE

No Results Yet

NCT06774521 | COMPLETED | NA

56 participants

Effectiveness of Pilates Exercises in the Treatment of Dysmenorrhea: A Randomized Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-01-15
Completion:: 2025-04-20

Conditions

Dysmenorrhea

Interventions

OTHER

No Results Yet

NCT06769334 | RECRUITING | NA

105 participants

Preparing for Life and Academics for Young Childhood Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-12-12
Completion:: 2026-11-01

Conditions

Childhood Cancer

Interventions

OTHER

No Results Yet

NCT06749184 | COMPLETED

110 participants

Predictors of Spinal Anesthesia-Induced Hypotension in Hypertensive Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-01-03
Completion:: 2025-06-10

Conditions

Spinal Anesthesia-Induced Hypotension

No Results Yet

NCT06745531 | COMPLETED | PHASE3

101 participants

A Phase 3 Study of TS-172 in Hyperphosphatemia Patients on Hemodialysis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-01-06
Completion:: 2025-10-13

Conditions

Hyperphosphatemia Patients on Hemodialysis

Interventions

DRUG

No Results Yet

NCT06735742 | ACTIVE_NOT_RECRUITING

3 participants

A Study to Learn About the Safety of TALZENNA for the Treatment of Breast Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-04-12
Completion:: 2029-03-30

Conditions

Breast Cancer

No Results Yet