Clinical Trials Updated in 2025

NCT06369363 | NOT_YET_RECRUITING | EARLY_PHASE1

20 participants

Estrogen Deficiency on Cardiovascular Risk

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2026-09-30
Completion:: 2028-09-30

Conditions

Postmenopausal Symptoms
Cardiovascular Diseases

Interventions

DRUG

No Results Yet

NCT06342830 | COMPLETED | PHASE2

60 participants

Comparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical Healing

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-06-20
Completion:: 2025-09-20

Conditions

Periapical Disease

Interventions

DRUG

No Results Yet

NCT06341049 | COMPLETED | NA

120 participants

Effect of Three Different Postcesarean Analgesic Techniques on QbsQor-10 Score

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-03-12
Completion:: 2025-05-02

Conditions

Postoperative Recovery

Interventions

PROCEDURE

No Results Yet

NCT06336174 | RECRUITING

100 participants

Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2022-11-01
Completion:: 2025-12-31

Conditions

Intracranial Atherosclerosis
Cognitive Impairment
Cerebrovascular Event

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06292598 | RECRUITING

120 participants

Bacterial Translocation and Gut Microbiota in Type 1 Narcolepsy Patients Versus a Control Population

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-03-10
Completion:: 2027-09-30

Conditions

Narcolepsy Type 1
Bacterial Translocation

Interventions

OTHER

No Results Yet

NCT06283719 | RECRUITING | PHASE1/PHASE2

265 participants

Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Advanced Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-09-02
Completion:: 2026-04-30

Conditions

Small Cell Lung Cancer
Neuroendocrine Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT06279078 | COMPLETED

19968 participants

Long-term Effect of Steroid on Metabolic Diseases in Asthmatics

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-12-30
Completion:: 2024-12-30

Conditions

Asthma
Osteoporosis, Osteopenia
Osteoporosis Risk
Osteoporotic Fractures

Interventions

DRUG

No Results Yet

NCT06258408 | RECRUITING | PHASE1

78 participants

A Phase 1 Study of BB102 in Participants With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2022-12-29
Completion:: 2026-12-31

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT06235476 | COMPLETED | NA

199 participants

Protein Intake and Exercise-induced Muscle Damage

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-06-10
Completion:: 2024-07-19

Conditions

Sarcopenia

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT06230744 | RECRUITING | NA

140 participants

A Novel Intervention for Weight Loss in Young Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-09-10
Completion:: 2028-08-31

Conditions

Weight Loss

Interventions

BEHAVIORAL

No Results Yet

NCT06206707 | RECRUITING | NA

20 participants

FMT in Checkpoint Inhibitor-mediated Diarrhea and Colitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-01-23
Completion:: 2026-06-30

Conditions

Diarrhea
Colitis
Malignant Melanoma
Kidney Cancer

Interventions

PROCEDURE

No Results Yet

NCT06190197 | RECRUITING | EARLY_PHASE1

120 participants

Prophylactic Antibiotics in Cystectomy With Diversion

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-05-13
Completion:: 2027-10-15

Conditions

Muscle-Invasive Bladder Carcinoma
Radical Cystectomy
Ileal Conduit
Neobladder Diversion

Interventions

DRUG

No Results Yet

NCT06184048 | COMPLETED | NA

20 participants

Validation of a Low-cost Platelet-Rich Plasma (PRP)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-09-15
Completion:: 2024-06-15

Conditions

Platelet-Rich Plasma (PRP)
Knee Osteoarthritis (OA)

Interventions

PROCEDURE

No Results Yet

NCT06173570 | COMPLETED | PHASE2

428 participants

A Study to Assess the Efficacy, Safety and Tolerability of Different Doses of AZD0780 in Patients With Dyslipidemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-01-19
Completion:: 2024-09-30

Conditions

Dyslipidemia

Interventions

DRUG

Results Available

NCT06170190 | COMPLETED | PHASE1/PHASE2

19 participants

A Multicentre,Study of IBI133 in Subjects WithUnresectable, Locally Advanced or Metastatic SolidTumours

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-01-16
Completion:: 2025-02-19

Conditions

Locally Advanced Unresectable or Metastatic Solid Tumors

Interventions

BIOLOGICAL

No Results Yet

NCT06143020 | COMPLETED | NA

100 participants

Effect of ESPB on Postoperative Pain in Patients With Breast Cancer Implant Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-11-20
Completion:: 2025-08-20

Conditions

Mammary Cancer
Erector Spinae Plane Block
Postoperative Pain

Interventions

PROCEDURE

No Results Yet

NCT06143007 | ACTIVE_NOT_RECRUITING | PHASE1

42 participants

A Phase 1 Study of BB3008 in Participants With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-10-26
Completion:: 2025-05-22

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT06118034 | RECRUITING | PHASE3

768 participants

Effect of Colchicine on Perioperative Anti-inflammatory Organ Injury in Cardiac Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-01-28
Completion:: 2026-08-31

Conditions

Inflammatory Response
Cardiac Disease

Interventions

DRUG

No Results Yet

NCT06085690 | RECRUITING | NA

8050 participants

Multicenter Clinical Translational Study of "ICU-NO CRBSI" Based on Improvement Science

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-09-04
Completion:: 2025-09-30

Conditions

CRBSI - Catheter Related Bloodstream Infection
Evidence-based Nursing Practice
Central Venous Catheter Related Bloodstream Infection
Central Venous Catheter Associated Bloodstream Infection
Central Line Infection
CLABSI - Central Line Associated Bloodstream Infection
Quality Improvement

Interventions

BEHAVIORAL

No Results Yet

NCT06084715 | COMPLETED

769 participants

The INSTITUT Study Tuberculosis Nutritional Support

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-09-07
Completion:: 2025-09-10

Conditions

Tuberculosis, Pulmonary
Undernutrition

Interventions

OTHER

No Results Yet

NCT06071026 | COMPLETED | NA

39 participants

Hemodynamic Effects of Variations in Net Ultrafiltration Rate During Continuous Renal Replacement Therapy.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-10-06
Completion:: 2025-07-08

Conditions

Fluid Overload
Hemodynamic Instability

Interventions

DEVICE

No Results Yet

NCT06065800 | COMPLETED

150 participants

STEELEX® Sternum Set + BONE WAX® + STEELEX® Electrode Set in Patients Undergoing Cardiac Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-05-17
Completion:: 2024-11-13

Conditions

Sternum Closure

Interventions

DEVICE

No Results Yet

NCT06052852 | TERMINATED | PHASE1

17 participants

Study of BDC-3042 as Single Agent and in Combination With Cemiplimab in Patients With Advanced Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-10-11
Completion:: 2025-08-01

Conditions

Triple Negative Breast Cancer
Clear Cell Renal Cell Carcinoma
Ovarian Cancer
Head and Neck Cancer
Colorectal Cancer
Non-small Cell Lung Cancer
Melanoma

Interventions

DRUG

No Results Yet

NCT06046131 | RECRUITING | NA

3000 participants

Clinical, Genetic and Environmental Determinants of Prostate Cancer Progression.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-02-28
Completion:: 2039-02-28

Conditions

Neoplasm Recurrence
Prostatic Neoplasm
Adenocarcinoma
Neoplasm Metastasis

Interventions

OTHER

No Results Yet

NCT06036212 | WITHDRAWN | NA

0 participants

Study to Evaluate Patient Outcomes and Safety and Effectiveness of Robotic Assisted Unicompartmental Knee Replacements Versus Conventional Unicompartmental Knee for Subjects With Primary Arthritis of the Knee Joint Involving One (UKA) Compartment (Medial or Lateral)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-11-21
Completion:: 2027-03-15

Conditions

Arthroplasty, Replacement, Knee
Unicompartmental Knee Arthroplasty

Interventions

DEVICE

No Results Yet

NCT06028945 | COMPLETED | NA

14 participants

Evaluating the Impact of Virtual Reality Exposure Therapy on Epilepsy/Seizure-Specific Interictal Anxiety

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-05-24
Completion:: 2024-11-11

Conditions

Epilepsy
Anxiety Disorders

Interventions

DEVICE

No Results Yet

NCT06017999 | COMPLETED | PHASE2/PHASE3

450 participants

XG005 for Pain Control in Subjects Undergoing Bunionectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-08-29
Completion:: 2024-08-29

Conditions

Acute Pain

Interventions

DRUG

Results Available

NCT06006156 | ACTIVE_NOT_RECRUITING | NA

20 participants

Dimensional Changes in Single Crowns Supported by Short Transmucosal Implants With Diverging or Converging Neck Profiles in the Esthetic Zone

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-04-01
Completion:: 2025-09-30

Conditions

Edentulous Alveolar Ridge

Interventions

PROCEDURE

No Results Yet

NCT05973864 | RECRUITING | PHASE2

220 participants

Capecitabine Plus Pembrolizumab in Patients With Triple Negative Breast Cancer After Chemo-immunotherapy and Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-03-11
Completion:: 2028-08-31

Conditions

Triple Negative Breast Neoplasms

Interventions

DRUG
RADIATION

No Results Yet

NCT05973487 | ACTIVE_NOT_RECRUITING | PHASE1

840 participants

A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-05-06
Completion:: 2026-12-30

Conditions

Head and Neck Cancer
Cervical Cancer
Non-small Cell Carcinoma
Melanoma
Ovarian Cancer
Anogenital Cancers
HPV - Anogenital Human Papilloma Virus Infection
HPV-Related Cervical Carcinoma
HPV-Related Carcinoma
HPV-Related Squamous Cell Carcinoma
HPV-Related Malignancy
HPV-Related Adenocarcinoma
HPV Positive Oropharyngeal Squamous Cell Carcinoma
HPV-Related Adenosquamous Carcinoma
HPV-Associated Vaginal Adenocarcinoma
HPV-Related Endocervical Adenocarcinoma
HPV-Related Anal Squamous Cell Carcinoma
HPV-Related Verrucous Carcinoma
HPV-Related Penile Squamous Cell Carcinoma
HPV-Related Vulvar Squamous Cell Carcinoma
HPV Positive Rectal Squamous Cell Carcinoma

Interventions

BIOLOGICAL

No Results Yet

NCT05964647 | COMPLETED | PHASE1

20 participants

Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-02-01
Completion:: 2025-06-30

Conditions

Healthy

Interventions

DRUG

No Results Yet

NCT05950685 | COMPLETED

1602 participants

Prediction of Long-term Arm Morbidity Following Breast Cancer Surgeries and Treatments

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-01-01
Completion:: 2025-05-01

Conditions

Breast Cancer

No Results Yet

NCT05929508 | RECRUITING | NA

30 participants

Improving Mobility and Function Following Transfemoral Amputation: A Novel Approach to Reverse Volumetric Muscle Loss

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-04-01
Completion:: 2027-06-01

Conditions

Traumatic Amputation of Lower Extremity

Interventions

OTHER

No Results Yet

NCT05924217 | ACTIVE_NOT_RECRUITING

300 participants

Gynecology Beyond Gender: Cervical Cancer Screening in Transgender Men in France

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-01-02
Completion:: 2025-01-01

Conditions

Cervical Cancer
Transgender Persons
Health Services for Transgender Persons

Interventions

OTHER

No Results Yet

NCT05893706 | COMPLETED

60 participants

The Effect of Single Task vs. Dual Task Assessment in Individuals With Knee Osteoarthritis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-06-06
Completion:: 2023-06-13

Conditions

Osteo Arthritis Knee

No Results Yet

NCT05888051 | COMPLETED

110 participants

Age-related Differences on Low Back Pain and Lower Extremity Isokinetic Muscle Strength and Balance

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-10-03
Completion:: 2023-10-03

Conditions

Back Pain

No Results Yet

NCT05858073 | COMPLETED | NA

114 participants

Investigation of Immediate Efficacy of Kinesiology Taping

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-06-01
Completion:: 2023-06-01

Conditions

Postural; Defect

Interventions

OTHER

No Results Yet

NCT05840406 | COMPLETED | NA

105 participants

Effect of a Transversus Abdominis Plane Block on Wound Healing, Stress, and Immune Response After a Cesarean Delivery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2024-09-03
Completion:: 2025-03-17

Conditions

Postoperative Pain
Cesarean Section
Wound Heal

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05836844 | RECRUITING

120 participants

Pragmatic Evaluation of Performance and Safety of the Anchorsure® Transvaginal Device for Surgical Treatment of Apical Prolapse in Women

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-17
Start Date:: 2023-05-11
Completion:: 2024-10-01

Conditions

Prolapse; Female
Prolapse Uterovaginal
Prolapse; Cervix

Interventions

DEVICE

No Results Yet

NCT05832671 | COMPLETED | NA

70 participants

Ultrasound Guided Erector Spinae Muscle Block in Pediatric Surgeries

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-17
Start Date:: 2025-04-03
Completion:: 2025-10-14

Conditions

Pediatric Hip Surgery

Interventions

PROCEDURE

No Results Yet