Study of BDC-3042 as Single Agent and in Combination With Cemiplimab in Patients With Advanced Malignancies
NCT06052852 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 17
Last updated 2025-11-17
Summary
A first-in-human study using BDC-3042 as a single agent and in combination with cemiplimab in patients with advanced malignancies
Conditions
Interventions
- DRUG
-
Drug which blocks checkpoint proteins from binding with their partner proteins, allowing T cells to kill cancer cells
- DRUG
-
BDC-3042
Dectin-2 agonist antibody
Sponsors & Collaborators
- collaborator INDUSTRY
-
Bolt Biotherapeutics, Inc.
lead INDUSTRY
Principal Investigators
-
Bolt Clinical Development · Bolt Biotherapeutics
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-10-11
- Primary Completion
- 2025-08-01
- Completion
- 2025-08-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
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