Clinical Trials Updated in 2025

NCT05559164 | RECRUITING | PHASE2

60 participants

Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2022-09-19
Completion:: 2026-09-01

Conditions

Cardiac Toxicity
Early-stage Breast Cancer

Interventions

DRUG

No Results Yet

NCT05544721 | ENROLLING_BY_INVITATION | PHASE4

50 participants

A Study of Paravertebral Block in Thoracic Outlet Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2022-10-05
Completion:: 2027-08-31

Conditions

Thoracic Outlet Syndrome

Interventions

DRUG

No Results Yet

NCT05534945 | RECRUITING | NA

60 participants

PIB for Post-operative Analgesia After Laparotomy : Determining the Optimum Dose

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2022-12-01
Completion:: 2026-07-31

Conditions

Acute Post Operative Pain
Laparotomy
Epidural Analgesia

Interventions

DRUG

No Results Yet

NCT05524428 | RECRUITING | NA

2 participants

Eliminating Barriers to Colorectal Cancer Screening Using Rapid Cycle Testing: A Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2023-03-24
Completion:: 2026-12-31

Conditions

Colo-rectal Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05480605 | COMPLETED

2 participants

Characterizing Occupational Therapy Intervention for Children With Autism Spectrum Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-14
Start Date:: 2022-04-19
Completion:: 2024-11-04

Conditions

Autism Spectrum Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05371405 | RECRUITING

120 participants

Machine Learning in Atrial Fibrillation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-14
Start Date:: 2020-02-12
Completion:: 2026-12-31

Conditions

Atrial Fibrillation
Arrhythmias, Cardiac

No Results Yet

NCT05350267 | COMPLETED | NA

35 participants

Changing Health and Lifestyle Behaviors of Offspring Following Maternal Bariatric Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2022-03-14
Completion:: 2025-03-10

Conditions

Obesity, Childhood

Interventions

BEHAVIORAL

No Results Yet

NCT05278104 | COMPLETED | NA

63 participants

A Study to Test Different Ways to Measure the Effect of Atomoxetine on Impulsive Behavior in Young Adults With Attention Deficit Hyperactivity Disorder (ADHD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2023-09-14
Completion:: 2024-10-23

Conditions

Attention Deficit Hyperactivity Disorder

Interventions

DRUG

Results Available

NCT05229783 | COMPLETED | NA

110 participants

High Resolution Virtual Chromoendoscopy Versus Seattle Protocol for the Surveillance of Barrett's Esophagus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2022-05-11
Completion:: 2024-12-03

Conditions

Barrett Esophagus

Interventions

PROCEDURE

No Results Yet

NCT05110300 | TERMINATED | NA

114 participants

A Multisite Exploration of Balance Perturbations With and Without Body Weight Support

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-12-15
Completion:: 2023-11-06

Conditions

Stroke
Stroke, Acute
Balance; Distorted
Balance; Impairment
Gait, Unsteady

Interventions

DEVICE

Results Available

NCT05086393 | COMPLETED | PHASE4

241 participants

Duloxetine RCT on Postop TKA Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-11-01
Completion:: 2025-06-01

Conditions

Pain, Postoperative
Total Knee Arthroplasty

Interventions

DRUG

No Results Yet

NCT05085457 | COMPLETED | NA

540 participants

The Use of ExPreS in the Weaning of Patients in Invasive Mechanical Ventilation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-11-01
Completion:: 2024-12-30

Conditions

Respiratory Insufficiency

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05078970 | RECRUITING | NA

306 participants

Advancing Suicide Intervention Strategies for Teens During High Risk Periods

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2022-08-11
Completion:: 2027-01-31

Conditions

Suicide Attempts
Suicidal Ideation
Suicide and Self-harm
Suicide Threat

Interventions

BEHAVIORAL

No Results Yet

NCT05055830 | RECRUITING

2000 participants

Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-10-05
Completion:: 2027-10-30

Conditions

Cardiac Disease
Critically Ill
Children, Adult

Interventions

DRUG

No Results Yet

NCT05045027 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

36 participants

Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-09-01
Completion:: 2026-09-10

Conditions

Glioma
Malignant Glioma
Recurrent Glioma
Recurrent Malignant Glioma

Interventions

PROCEDURE

No Results Yet

NCT05044845 | COMPLETED

150 participants

Needs Assessment of Knowledge, Beliefs, and Attitudes of Patients With Hemophilia B About Gene Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-14
Start Date:: 2022-01-18
Completion:: 2025-10-14

Conditions

Gene Therapy
Hemophilia B

Interventions

BEHAVIORAL

No Results Yet

NCT05024929 | RECRUITING

32 participants

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-07-16
Completion:: 2031-02-01

Conditions

Papillary Thyroid Cancer
Pediatric Cancer
Differentiated Thyroid Cancer

Interventions

PROCEDURE

No Results Yet

NCT04982835 | ACTIVE_NOT_RECRUITING | NA

156 participants

M6-C Artificial Cervical Disc Two-Level IDE Pivotal Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-07-26
Completion:: 2025-12-31

Conditions

Cervical Disc Degenerative Disorder

Interventions

DEVICE

No Results Yet

NCT04945369 | RECRUITING | NA

114 participants

Follow-up During the Peripubertal Period of Preterm Children Included in the Protocol Entitled "EPIPOD".

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2022-02-02
Completion:: 2028-02-02

Conditions

Preterm Children

Interventions

OTHER

No Results Yet

NCT04937400 | ACTIVE_NOT_RECRUITING

1040 participants

Delirium in Children Undergoing Stem Cell Transplantation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-07-12
Completion:: 2026-07-30

Conditions

Stem Cell Transplant Complications
Delirium

Interventions

OTHER

No Results Yet

NCT04895033 | COMPLETED | NA

52 participants

Brain Responses to Contextual Influences on Drinking Decisions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2023-02-01
Completion:: 2025-07-31

Conditions

Alcohol Drinking

Interventions

BEHAVIORAL

No Results Yet

NCT04876391 | COMPLETED | PHASE2

45 participants

A Study Investigating Long-term Treatment With Spesolimab in People With a Skin Disease Called Hidradenitis Suppurativa Who Completed a Previous Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-08-24
Completion:: 2024-04-26

Conditions

Hidradenitis Suppurativa

Interventions

DRUG

Results Available

NCT04833907 | ENROLLING_BY_INVITATION | PHASE1/PHASE2

24 participants

rAAV-Olig001-ASPA Gene Therapy for Treatment of Children With Typical Canavan Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-04-01
Completion:: 2026-08-31

Conditions

Canavan Disease

Interventions

DRUG

No Results Yet

NCT04833829 | ACTIVE_NOT_RECRUITING | NA

850 participants

Cross-disciplinary HIV Integrated Mental Health Support Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2020-11-01
Completion:: 2026-11-30

Conditions

Human Immunodeficiency Virus
HIV Infections

Interventions

BEHAVIORAL

No Results Yet

NCT04802603 | RECRUITING | NA

60 participants

Dose-Escalated Spine SbRT for Localized Metastasis to the Spinal Column

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-03-14
Completion:: 2029-09-28

Conditions

Spine Metastases
Metastasis Spine

Interventions

RADIATION

No Results Yet

NCT04677777 | COMPLETED | PHASE1

24 participants

Safety Study of PP-007 in Subjects With Acute Ischemic Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2024-04-24
Completion:: 2025-02-20

Conditions

Acute Ischemic Stroke

Interventions

BIOLOGICAL

No Results Yet

NCT04656041 | RECRUITING | PHASE2

40 participants

Folfox+Irinotecan+Chemort In Esophageal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-06-29
Completion:: 2024-04-30

Conditions

Gastroesophageal Junction Adenocarcinoma
Esophagogastric Cancer

Interventions

DRUG
RADIATION

No Results Yet

NCT04636177 | COMPLETED | NA

34 participants

Pain Rehabilitation Virtual Reality (PRVR): Innovations to Enhance Mobility in the Presence of Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2022-03-10
Completion:: 2024-12-07

Conditions

Chronic Pain
Musculoskeletal Pain
Fibromyalgia
Virtual Reality

Interventions

BEHAVIORAL

Results Available

NCT04610515 | COMPLETED

6000 participants

Innovative Support for Patients With SARS-COV2 Infections (COVID-19) Registry (INSPIRE)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-14
Start Date:: 2020-12-15
Completion:: 2024-08-31

Conditions

Covid19
ME/CFS
SARS COV2
Novel Coronavirus Infection
Neurocognitive Disorders
Cardiovascular Diseases

No Results Yet

NCT04561362 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

329 participants

Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2020-07-17
Completion:: 2026-03-31

Conditions

Urinary Bladder Neoplasm
Triple Negative Breast Neoplasms
Hormone Receptor Positive, HER2-negative Neoplasms
Hormone Receptor Positive, HER2-low Neoplasms
Breast Neoplasms
Non-Small-Cell Lung Neoplasms
Ovarian Neoplasm
Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT04473833 | RECRUITING | NA

65000 participants

Transvaginal Ultrasonography as a Screening Method for Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 1988-12-19
Completion:: 2026-12-31

Conditions

Ovarian Cancer

Interventions

PROCEDURE

No Results Yet

NCT04373629 | RECRUITING | NA

146 participants

Perceptual Abnormalities and Their Malleability in BDD

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2020-12-01
Completion:: 2025-12-01

Conditions

Body Dysmorphic Disorder

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT04364854 | COMPLETED | PHASE2

80 participants

Speech Entrainment for Aphasia Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2020-08-21
Completion:: 2024-05-08

Conditions

Aphasia
Aphasia Non Fluent
Stroke

Interventions

BEHAVIORAL
OTHER

Results Available

NCT04323488 | COMPLETED | NA

90 participants

Neural Mechanisms of Successful Intervention in Children With Dyslexia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-05-01
Completion:: 2024-09-01

Conditions

Dyslexia, Developmental

Interventions

BEHAVIORAL

Results Available

NCT04219956 | RECRUITING | NA

278 participants

Study to Evaluate the Efficacy of a Polyamine-deficient Diet for Treating Postoperative Pain After Abdominal Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2020-02-03
Completion:: 2027-04-30

Conditions

Digestive System Surgical Procedures

Interventions

OTHER

No Results Yet

NCT04168203 | COMPLETED | PHASE4

600 participants

Extended-Duration Low-Intensity Apixaban to Prevent Recurrence in High-Risk Patients With Provoked Venous Thromboembolism

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2021-03-01
Completion:: 2023-11-30

Conditions

Deep Vein Thrombosis
Pulmonary Embolism
Venous Thromboembolism

Interventions

DRUG

Results Available

NCT04106492 | TERMINATED | PHASE1/PHASE2

53 participants

Phase 1/2a Study of SQ3370 in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2020-08-01
Completion:: 2023-09-07

Conditions

Cancer

Interventions

DRUG

Results Available

NCT04071327 | RECRUITING

3000 participants

Pulmonary Hypertension Association Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-14
Start Date:: 2015-10-31
Completion:: 2025-12-31

Conditions

Pulmonary Arterial Hypertension
Chronic Thromboembolic Pulmonary Hypertension
Pulmonary Hypertension

No Results Yet

NCT04070378 | COMPLETED | PHASE2

16 participants

Study of Daratumumab in Patients With Mild to Moderate Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2019-11-06
Completion:: 2023-06-08

Conditions

Alzheimer Disease

Interventions

DRUG

Results Available

NCT04060277 | ACTIVE_NOT_RECRUITING | PHASE2

7 participants

Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-14
Start Date:: 2019-11-27
Completion:: 2023-06-06

Conditions

Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Acute Lymphoblastic Leukemia
Acute Myeloid Leukemia
Chronic Lymphocytic Leukemia
Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Hematopoietic and Lymphoid Cell Neoplasm
Hodgkin Lymphoma
Lymphoblastic Lymphoma
Myelodysplastic Syndrome
Myelofibrosis
Myeloproliferative Neoplasm
Non-Hodgkin Lymphoma

Interventions

DRUG
BIOLOGICAL
OTHER

Results Available