Clinical Trials Updated in 2025

NCT07227688 | ACTIVE_NOT_RECRUITING | NA

90 participants

Evaluation of the Proximal Form of Precontoured Sectional Matrix in Complex Proximal Posterior Restorations

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-01-01
Completion:: 2025-11-30

Conditions

Complex Caries

Interventions

DEVICE

No Results Yet

NCT07227675 | COMPLETED | NA

162 participants

Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2017-10-23
Completion:: 2019-03-14

Conditions

Mitral Regurgitation
Mitral Valve Regurgitation

Interventions

DEVICE

No Results Yet

NCT07224932 | NOT_YET_RECRUITING | PHASE2

60 participants

Tolerability and Efficacy of CBD Extract for RLS Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-12-19
Completion:: 2026-01-01

Conditions

Restless Leg Syndrome

Interventions

DRUG

No Results Yet

NCT07214935 | COMPLETED | PHASE1

36 participants

A TQT Study of Effect of M2951 on Cardiac Repolarization

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2022-11-08
Completion:: 2023-08-25

Conditions

Healthy

Interventions

DRUG

Results Available

NCT07213661 | RECRUITING | NA

480 participants

LT Comparative Effectiveness of 2 Caries Treatments

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-10-08
Completion:: 2030-01-31

Conditions

Dental Caries

Interventions

DEVICE

No Results Yet

NCT07162272 | COMPLETED | PHASE4

52 participants

The Efficacy of Melatonin Patches on Dental Anxiety in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-06-25
Completion:: 2025-08-28

Conditions

Dental Anxiety
Children

Interventions

DRUG
OTHER

No Results Yet

NCT07158164 | RECRUITING | PHASE4

100 participants

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-08-27
Completion:: 2027-07-07

Conditions

Colorectal Neoplasms
Breast Neoplasms
Head and Neck Neoplasms
Gastro-Intestinal Intraepithelial Neoplasia

Interventions

DRUG

No Results Yet

NCT07124702 | RECRUITING | NA

45 participants

Cessation of Dual Use of Cigarettes and E-cigarettes During Pregnancy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-10-01
Completion:: 2026-09-30

Conditions

Dual Use of Cigarettes and E-cigarettes
Gestational Weight Gain
Birth-weight-for-gestational-age z Score

Interventions

BEHAVIORAL

No Results Yet

NCT07068074 | NOT_YET_RECRUITING | PHASE3

428 participants

A Randomized Phase III Study of Management of Treatment Naive Primary Melanoma in Elderly Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-12-12
Completion:: 2031-01-01

Conditions

Cutaneous Melanoma

Interventions

PROCEDURE

No Results Yet

NCT07063420 | RECRUITING | NA

18 participants

Patient Centered Multi-Agent Decision Support System (PCM-DSS) for Healthcare Providers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-10-28
Completion:: 2026-07-31

Conditions

Type 2 Diabetes Treated With Insulin

Interventions

OTHER

No Results Yet

NCT06923995 | RECRUITING | NA

120 participants

Expansion and Evaluation of AI-generated Clinical Assessment (AI-COA®) of Depression and Anxiety Severity

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-09-01
Completion:: 2026-02-28

Conditions

Depression Disorders
Anxiety Disorders

Interventions

OTHER

No Results Yet

NCT06919991 | COMPLETED | PHASE1

14 participants

Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-05-02
Completion:: 2025-10-18

Conditions

Healthy Participants

Interventions

DRUG

No Results Yet

NCT06867484 | RECRUITING | NA

114 participants

Breast Re-irradiation After Second Ipsilateral Lumpectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-10-27
Completion:: 2028-05-31

Conditions

Breast Cancer
Cancer
Cancer of the Breast
HER2-negative Breast Cancer
ER+ Breast Cancer
Estrogen-receptor-positive Breast Cancer

Interventions

RADIATION

No Results Yet

NCT06763432 | RECRUITING

45 participants

Positive Fit to Colonoscopy: Closing the Gap

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-06-16
Completion:: 2029-08-31

Conditions

Colorectal Cancer Screening

No Results Yet

NCT06757192 | RECRUITING

40 participants

CRC Screening in Unscreened Individuals 45-54

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-06-16
Completion:: 2029-08-31

Conditions

Colorectal Cancer Screening

No Results Yet

NCT06677112 | RECRUITING | NA

625 participants

MCC-24-GYN-11: Comparison of Nodal Sampling in Endometrial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-03-17
Completion:: 2030-01-31

Conditions

Endometrial Cancer

Interventions

PROCEDURE

No Results Yet

NCT06519097 | ACTIVE_NOT_RECRUITING | PHASE2

4 participants

Study of IPMN Progression Prevention With Tocotrienol (SIPP-T3)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2024-07-09
Completion:: 2026-09-30

Conditions

Neoplasm of Pancreas
IPMN, Pancreatic

Interventions

DRUG
OTHER

No Results Yet

NCT06463613 | ACTIVE_NOT_RECRUITING | NA

200 participants

Using a Novel Skin Tag Removal Device

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2024-06-03
Completion:: 2025-11-30

Conditions

Achrochordon

Interventions

DEVICE

No Results Yet

NCT06454916 | COMPLETED | NA

79 participants

Functional Lumen Opening With Self-Forming Magnetic Anastomosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2024-10-04
Completion:: 2025-06-30

Conditions

Small Bowel Anastomosis

Interventions

DEVICE

No Results Yet

NCT06403852 | COMPLETED | PHASE2

36 participants

Investigating Near-Threshold Perception During Anesthetic Sedation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2024-05-10
Completion:: 2025-10-03

Conditions

Propofol
Anesthesia
fMRI

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06396091 | ACTIVE_NOT_RECRUITING | PHASE1

12 participants

A Study of Zolbetuximab With Chemotherapy in Adults With Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-09-24
Completion:: 2026-07-31

Conditions

Metastatic Pancreatic Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT06348875 | NOT_YET_RECRUITING

50 participants

Clinical Evaluation of Radiation Reduction for Optimized Safety

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-13
Start Date:: 2026-02-15
Completion:: 2026-06-15

Conditions

Coronary Artery Disease
Myocardial Infarction
Coronary Disease
Coronary Stenosis
Angina Pectoris
Chest Pain

No Results Yet

NCT06328127 | RECRUITING | NA

400 participants

Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2024-12-17
Completion:: 2029-05-31

Conditions

Hematopoietic Stem Cell Transplant

Interventions

BEHAVIORAL

No Results Yet

NCT06263738 | RECRUITING | NA

162 participants

Cold and Heat Investigation to Lower Levels of Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2024-05-14
Completion:: 2027-04-01

Conditions

Depression
Mood Disorders
Healthy (Controls)

Interventions

PROCEDURE

No Results Yet

NCT06207864 | RECRUITING | NA

1001 participants

Engagement of American Indians of Southwestern Tribal Nations in Cancer Genome Sequencing

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2022-03-22
Completion:: 2028-12-31

Conditions

Malignant Neoplasm

Interventions

PROCEDURE
OTHER

No Results Yet

NCT06192641 | COMPLETED | PHASE2

24 participants

Melatonin Use in Patients With Climacterious Symptoms in the Perimenopause

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2023-10-20
Completion:: 2024-11-30

Conditions

Perimenopausal Disorder

Interventions

DRUG

No Results Yet

NCT06169540 | RECRUITING

90 participants

Salivary Extracellular Vesicle Associated lncRNAs in Heart Failure (SEAL-HF)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-13
Start Date:: 2023-04-19
Completion:: 2026-12-31

Conditions

CHF
ADHF
Control

No Results Yet

NCT06094088 | RECRUITING | NA

120 participants

Researching Heat and Yoga for Mood Enhancement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2025-07-01
Completion:: 2026-09-01

Conditions

Depression

Interventions

BEHAVIORAL

No Results Yet

NCT06063161 | COMPLETED | NA

30 participants

Music Therapy to Prevent Hospital-acquired Delirium in Parkinson's Disease and Dementia With Lewy Bodies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2024-04-01
Completion:: 2025-07-01

Conditions

Parkinson Disease
Dementia, Lewy Body
Delirium

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06055894 | RECRUITING | NA

200 participants

A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM) or Monoclonal Gammopathy of Undetermined Significance (MGUS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2023-09-20
Completion:: 2026-09-30

Conditions

Multiple Myeloma, Smoldering
Multiple Myeloma
Monoclonal Gammopathy of Undetermined Significance

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT06052943 | RECRUITING | NA

175 participants

Health Without Barriers/Salud Sin Barreras

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2022-09-21
Completion:: 2027-06-30

Conditions

Mental Health Wellness
Family Research
Lifestyle Risk Reduction

Interventions

BEHAVIORAL

No Results Yet

NCT06033365 | COMPLETED | NA

192 participants

Beginning Early and Assertive Treatment for Methamphetamine Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2023-04-11
Completion:: 2024-12-31

Conditions

Methamphetamine Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06020014 | COMPLETED | PHASE2

339 participants

Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-Severe Asthma Uncontrolled on Medium-High Dose ICS-LABA

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2023-11-16
Completion:: 2025-10-28

Conditions

Asthma

Interventions

DRUG
OTHER

No Results Yet

NCT06006078 | COMPLETED | NA

57 participants

Aerosolization During Upper Endoscopy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2021-08-31
Completion:: 2021-10-15

Conditions

Infectious
Gastro-Intestinal Disorder
Safety Issues

Interventions

DEVICE

Results Available

NCT05997017 | RECRUITING | PHASE2

29 participants

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2023-12-28
Completion:: 2026-12-31

Conditions

Endometrial Cancer
Endometrioid Tumor
Cancer
Tumor
Recurrent Endometrial Carcinoma
Endometrioid Endometrial Cancer

Interventions

DRUG

No Results Yet

NCT05993611 | SUSPENDED | PHASE1

27 participants

Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2024-02-19
Completion:: 2028-05-21

Conditions

Chronic Graft Versus Host Disease
Hematologic and Lymphocytic Disorder
Steroid Refractory Graft Versus Host Disease

Interventions

OTHER
PROCEDURE
BIOLOGICAL

No Results Yet

NCT05968742 | RECRUITING | NA

80 participants

Variation in Gingival Inflammatory Responses

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2023-06-30
Completion:: 2026-10-01

Conditions

Gingivitis

Interventions

BEHAVIORAL

No Results Yet

NCT05966805 | COMPLETED | NA

21 participants

Impact of Exercise Intervention on Well-being in Shift-working Acute Care Nurses

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2023-09-13
Completion:: 2025-05-13

Conditions

Psychological Wellness

Interventions

BEHAVIORAL

No Results Yet

NCT05954871 | COMPLETED | PHASE1

10 participants

Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertinib in Participants With Unresectable, Locally Advanced, or Metastatic Non-Small Cell Lung Cancer, or With Cetuximab in Participants With Metastatic Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2024-01-08
Completion:: 2025-09-16

Conditions

Colorectal Cancer
Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05949177 | RECRUITING | NA

50 participants

Graded Exposure and Mindfulness Meditation for Patients Post-ACL Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-13
Start Date:: 2024-10-30
Completion:: 2026-07-31

Conditions

Anterior Cruciate Ligament Injuries

Interventions

BEHAVIORAL

No Results Yet