Clinical Trials Updated in 2025

NCT04968743 | COMPLETED | NA

24 participants

Phase-dependent Evaluation of Motor Cortex Excitability With TMS in Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2021-10-01
Completion:: 2025-10-01

Conditions

Stroke

Interventions

DEVICE

No Results Yet

NCT04947800 | TERMINATED | NA

13 participants

Acupuncture to Enhance for Pulmonary Rehab

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2022-01-25
Completion:: 2024-06-01

Conditions

COPD

Interventions

DEVICE

Results Available

NCT04916210 | RECRUITING

8000 participants

Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-03
Start Date:: 2021-03-05
Completion:: 2026-08-31

Conditions

Ischemic Stroke
Intracerebral Hemorrhage
Subarachnoid Hemorrhage
Dementia, Vascular
Mild Cognitive Impairment
Vascular Cognitive Impairment

No Results Yet

NCT04874194 | TERMINATED | PHASE1/PHASE2

24 participants

Omacetaxine and Venetoclax for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Harboring Mutant RUNX1

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2021-12-17
Completion:: 2024-09-16

Conditions

Hematopoietic and Lymphoid Cell Neoplasm
Recurrent Acute Biphenotypic Leukemia
Recurrent Acute Myeloid Leukemia
Recurrent Myelodysplastic Syndrome
Refractory Acute Biphenotypic Leukemia
Refractory Acute Myeloid Leukemia
Refractory Myelodysplastic Syndrome

Interventions

DRUG

Results Available

NCT04828382 | ACTIVE_NOT_RECRUITING

285 participants

Prospective Study of Pregnancy in Women With Cystic Fibrosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-03
Start Date:: 2021-09-30
Completion:: 2027-06-30

Conditions

Pregnancy Related
Cystic Fibrosis

No Results Yet

NCT04735653 | COMPLETED | NA

236 participants

The Support, Educate, Empower (SEE) Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2021-04-27
Completion:: 2024-07-31

Conditions

Glaucoma

Interventions

BEHAVIORAL

Results Available

NCT04643418 | RECRUITING | PHASE1/PHASE2

81 participants

Phase 1/2a Study of MPB-1734 in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2022-03-08
Completion:: 2025-03-31

Conditions

Solid Tumor, Unspecified, Adult

Interventions

DRUG

No Results Yet

NCT04527185 | COMPLETED | PHASE2

27 participants

Effect of Endotoxin on Alcohol Consumption

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2022-02-27
Completion:: 2024-10-31

Conditions

Alcohol Use Disorder

Interventions

DRUG

Results Available

NCT04428476 | ACTIVE_NOT_RECRUITING | PHASE2

13 participants

Open-label Extension of the HOPE-2 Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2020-08-05
Completion:: 2022-02-16

Conditions

Duchenne Muscular Dystrophy

Interventions

BIOLOGICAL

Results Available

NCT04373369 | TERMINATED | PHASE2

11 participants

Vorolanib + Atezolizumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2020-10-07
Completion:: 2022-08-18

Conditions

Extensive-stage Small Cell Lung Cancer

Interventions

DRUG

Results Available

NCT04362501 | COMPLETED | PHASE2

33 participants

Efficacy of Dupilumab for Patients With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2020-10-15
Completion:: 2025-09-30

Conditions

Chronic Sinusitis

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT04319276 | ACTIVE_NOT_RECRUITING | PHASE1

26 participants

Oral Gallium Maltolate for the Treatment of Relapsed and Refractory Glioblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2022-11-11
Completion:: 2025-02-13

Conditions

Glioblastoma

Interventions

DRUG

No Results Yet

NCT04302727 | COMPLETED | NA

360 participants

Delicious Eating for Life in Southern Homes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2020-07-06
Completion:: 2024-06-16

Conditions

Weight Loss
Diet, Healthy
Cardiovascular Risk Factor

Interventions

BEHAVIORAL

Results Available

NCT04289116 | COMPLETED | NA

71 participants

Enhancing Sexual Safety: Couples' Communication and HIV Testing Among YMSM

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2020-01-20
Completion:: 2022-05-31

Conditions

HIV/AIDS
HIV Infections

Interventions

BEHAVIORAL

Results Available

NCT04244162 | COMPLETED

32 participants

Postoperative Neurocognitive Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-03
Start Date:: 2020-12-12
Completion:: 2024-12-31

Conditions

Obstructive Sleep Apnea
Neurocognitive Disorders

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04232696 | ACTIVE_NOT_RECRUITING | NA

331 participants

Neuspera's Implantable Sacral Nerve Stimulation System in Patients With Symptoms of Urinary Urgency Incontinence (UUI)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2019-12-13
Completion:: 2024-07-17

Conditions

Urinary Urgency Incontinence

Interventions

DEVICE

Results Available

NCT03860961 | COMPLETED | NA

550 participants

Increasing the Dose of Survivorship Care Planning in Improving Care and Outcomes in Prostate Cancer Survivors Receiving Androgen Deprivation Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2019-07-26
Completion:: 2024-11-14

Conditions

Prostate Adenocarcinoma

Interventions

OTHER

Results Available

NCT03845582 | COMPLETED | PHASE2/PHASE3

200 participants

Phase 2/3 Study of ALK-001 in Geographic Atrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2019-05-07
Completion:: 2023-07-25

Conditions

Geographic Atrophy
Age Related Macular Degeneration
AMD
Atrophy, Geographic

Interventions

DRUG

Results Available

NCT03707938 | ACTIVE_NOT_RECRUITING | PHASE1

35 participants

Local Consolidative Therapy and Brigatinib in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2018-12-18
Completion:: 2026-01-28

Conditions

Advanced Lung Carcinoma
ALK Gene Rearrangement
Lung Non-Small Cell Carcinoma
Recurrent Lung Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8
Stage IVA Lung Cancer AJCC v8
Stage IVB Lung Cancer AJCC v8

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03694691 | RECRUITING | NA

60 participants

Developing Viability Index for Machine Perfused Livers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2018-10-01
Completion:: 2028-12-01

Conditions

Liver Cirrhoses

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03688126 | COMPLETED | NA

2000 participants

U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2019-01-08
Completion:: 2025-05-16

Conditions

Alzheimer Disease

Interventions

BEHAVIORAL

No Results Yet

NCT03473145 | COMPLETED | NA

407 participants

Sedentary Behavior Interrupted Randomized Controlled Trial (P2)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2018-05-30
Completion:: 2022-12-31

Conditions

Sedentary Lifestyle

Interventions

BEHAVIORAL
DEVICE
OTHER

Results Available

NCT03092726 | COMPLETED | PHASE2

183 participants

A Study to Assess the Analgesic Efficacy and Safety of ASP8062 in Subjects With Fibromyalgia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2017-05-08
Completion:: 2018-03-06

Conditions

Fibromyalgia

Interventions

DRUG

Results Available

NCT02780648 | COMPLETED | NA

36 participants

Respiratory-gated Stereotactic Body Radiation Therapy for Adenocarcinoma of the Pancreas or Periampullary Region

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2016-05-01
Completion:: 2019-12-17

Conditions

Pancreatic Neoplasms

Interventions

RADIATION

Results Available

NCT02600494 | COMPLETED | PHASE3

554 participants

Clinical Trial Evaluating ITI-007 (Lumateperone) as a Monotherapy for the Treatment of Bipolar Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2015-12-15
Completion:: 2019-01-28

Conditions

Bipolar Depression

Interventions

DRUG

Results Available

NCT02452528 | TERMINATED | PHASE2

4 participants

Study of ARC-520 in Participants With Hepatitis B Virus e Antigen (HBeAg) Positive Chronic Hepatitis B Virus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2015-08-31
Completion:: 2016-12-31

Conditions

Chronic Hepatitis B

Interventions

DRUG

Results Available

NCT02327364 | COMPLETED

11 participants

Natural History of Pearson Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-03
Start Date:: 2014-03-31
Completion:: 2020-08-31

Conditions

Pearson Syndrome

No Results Yet

NCT02199665 | COMPLETED | PHASE1

52 participants

Selinexor, Carfilzomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2014-06-12
Completion:: 2025-10-31

Conditions

Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT02162732 | COMPLETED | NA

186 participants

Molecular-Guided Therapy for Childhood Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2014-07-08
Completion:: 2024-01-18

Conditions

Neuroblastoma
Medulloblastoma
Glioma
Ependymoma
Choroid Plexus Neoplasms
Craniopharyngioma
Dysembryoplastic Neuroepithelial Tumor
Meningioma
Primitive Neuroectodermal Tumors (PNETs)
Germ Cell Tumors
Rhabdomyosarcoma
Non-rhabdomyosarcoma
Ewings Sarcoma
Osteosarcoma
Wilms Tumor
Renal Cell Carcinoma
Malignant Rhabdoid Tumor
Clear Cell Sarcoma
Liver Tumors

Interventions

DEVICE

Results Available

NCT01191697 | COMPLETED | PHASE2

37 participants

CAPOX, Bevacizumab and Trastuzumab for Patients With HER2-Positive Metastatic Esophagogastric Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-03
Start Date:: 2011-02-28
Completion:: 2021-12-31

Conditions

Esophageal Cancer
Gastric Cancer

Interventions

DRUG

Results Available

NCT07223476 | COMPLETED

1926 participants

Treatment Landscape and Real-World Dosing Patterns With CDK4/6 Inhibitors for Breast Cancer in Portugal

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-03-29
Completion:: 2024-07-01

Conditions

Breast Cancer

No Results Yet

NCT07223359 | COMPLETED | NA

59 participants

Photographic Evidence on Total Knee Arthroplasty Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2020-01-01
Completion:: 2021-12-31

Conditions

Osteoarthritis (OA) of the Knee

Interventions

BEHAVIORAL

No Results Yet

NCT07223346 | RECRUITING | NA

20 participants

Latinas Integrating Fitness and Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-10-01
Completion:: 2026-12-31

Conditions

Stepped Care Cognitive Behavioral Therapy
Exercise
Physical Activity
Anxiety Depression

Interventions

BEHAVIORAL

No Results Yet

NCT07223268 | RECRUITING | NA

270 participants

Comprehensive Assistance and Resources for Effective Diabetic Foot Navigation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-10-07
Completion:: 2030-08-31

Conditions

Diabetic Foot Ulcer

Interventions

OTHER

No Results Yet

NCT07223242 | RECRUITING | PHASE2/PHASE3

120 participants

Tailored Exercise Training Study Among Adults With HFpEF

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-02-18
Completion:: 2026-12-30

Conditions

HFpEF - Heart Failure With Preserved Ejection Fraction
Diabetic Cardiomyopathies

Interventions

BEHAVIORAL
DRUG

No Results Yet

NCT07223073 | COMPLETED | PHASE3

80 participants

A Clinical Study Conducted in the Bangkok, Thailand Area, to Investigate the Clinical Efficacy of a New Toothpaste

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2017-12-21
Completion:: 2018-01-12

Conditions

Oral Malodor

Interventions

DRUG

No Results Yet

NCT07222982 | RECRUITING | NA

54 participants

Social Groups for Autistic Young Adults (SDARIYA)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2026-01-15
Completion:: 2030-02-28

Conditions

Autism Spectrum Disorder

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT07222618 | RECRUITING

300 participants

"Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-10-01
Completion:: 2028-10-01

Conditions

Multiple Sclerosis
Multiple Sclerosis (MS) - Relapsing-remitting
Multiple Sclerosis (MS) Primary Progressive
MS (Multiple Sclerosis)
MS
Multiple Sclerosis (MS) Secondary Progressive

No Results Yet

NCT07203885 | COMPLETED | NA

10 participants

AI-Assisted Acute Myeloid Leukemia Evaluation With the Leukemia End-to-End Analysis Platform (LEAP) Versus Clinician-Only Assessment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-09-09
Completion:: 2025-10-10

Conditions

Acute Promyelocytic Leukemia (APL)
Acute Myeloid Leukaemia (AML)

Interventions

BEHAVIORAL

No Results Yet

NCT07164846 | RECRUITING | NA

30 participants

Effect of Neuro20 Functional Electrical Stimulation Suit on Autonomic Function, Muscle Performance, and Gait

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-08-05
Completion:: 2026-08-01

Conditions

Spinal Cord Injury
Stroke
Amputees

Interventions

DEVICE

No Results Yet