Clinical Trials Updated in 2025

NCT06866743 | COMPLETED

18 participants

How Seasons Affect Kidney Health in Post-Menopausal Females

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2025-01-03
Completion:: 2025-09-03

Conditions

Postmenopausal
Female

Interventions

OTHER

No Results Yet

NCT06838000 | ACTIVE_NOT_RECRUITING | PHASE3

1268 participants

Study of the Safety and Immunogenicity of Catch-up Vaccination With a 21-valent Pneumococcal Conjugate Vaccine (PCV21) in Healthy Infants, Toddlers, Children, and Adolescents

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2025-02-28
Completion:: 2026-12-01

Conditions

Pneumococcal Infections

Interventions

BIOLOGICAL

No Results Yet

NCT06834490 | COMPLETED | PHASE3

318 participants

Safety and Efficacy of Sequential Therapy With Mexidol® in Patients With Chronic Cerebral Ischemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2019-11-05
Completion:: 2020-12-08

Conditions

Chronic Cerebral Ischemia

Interventions

DRUG

Results Available

NCT06828055 | COMPLETED | PHASE2

280 participants

VK2735 for Weight Management Phase 2 (Venture Oral Dosing)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-12-18
Completion:: 2025-06-24

Conditions

Weight Loss

Interventions

DRUG

No Results Yet

NCT06824545 | NOT_YET_RECRUITING

180 participants

Incidence & Clinical Significance of Osteolysis Following PEEK Suture Anchor Use in Hand & Wrist Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2026-01-01
Completion:: 2026-12-10

Conditions

Osteolysis

No Results Yet

NCT06794177 | COMPLETED | NA

30 participants

The Effects of Dual Task Training With Different Task Priorities on Physical Performance and Cognitive Status in Patients With Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-02-01
Completion:: 2025-09-30

Conditions

Parkinson's Disease (PD)
Dual-task
Balance
Walking
Mobility
Cognition

Interventions

OTHER

No Results Yet

NCT06746402 | COMPLETED | PHASE1

42 participants

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of BMS-986278 and the Effects of BMS-986278 on Cardiac Repolarization in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2025-02-10
Completion:: 2025-09-11

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT06730100 | WITHDRAWN | PHASE2

0 participants

CBX-12 for the Treatment of Metastatic Chemotherapy-Refractory Microsatellite Stable Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2026-02-17
Completion:: 2026-12-01

Conditions

Metastatic Mismatch Repair Proficient Colorectal Carcinoma
Refractory Mismatch Repair Proficient Colorectal Carcinoma
Stage IV Colorectal Cancer AJCC v8

Interventions

PROCEDURE
DRUG

No Results Yet

NCT06676826 | RECRUITING | NA

80 participants

Treatment of Periodontal Intra-bony Defects With a Volume Stable Collagen Matrix or Deproteinized Bovine Bone Mineral With 10% Collagen

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2025-09-01
Completion:: 2026-09-30

Conditions

Periodontal Diseases

Interventions

DEVICE

No Results Yet

NCT06676111 | COMPLETED | NA

72 participants

Effectiveness of Probiotics in Relieving Allergic Rhinitis in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-10-10
Completion:: 2025-02-10

Conditions

Children With Allergic Rhinitis

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06671054 | RECRUITING | PHASE2

240 participants

A Dose Response Study to Evaluate the Efficacy and Safety of Oral AP1189 Administered in Disease-Modifying Anti-Rheumatic Drug (DMARD) naïve Participants Participants With Early Rheumatoid Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-10-01
Completion:: 2025-12-31

Conditions

Rheumatoid Arthritis (RA)

Interventions

DRUG

No Results Yet

NCT06634810 | RECRUITING | NA

300 participants

Comprehensive Patient-Centered Home-based Care Coaching for COPD Self-management

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-09-25
Completion:: 2027-01-31

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

BEHAVIORAL

No Results Yet

NCT06628401 | COMPLETED | NA

42 participants

Comparing Approaches to Increasing Fruit and Vegetable Intake and Their Influence on Metabolic Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-10-23
Completion:: 2025-03-21

Conditions

Metabolic Health
Fruit and Vegetable Intake

Interventions

BEHAVIORAL

No Results Yet

NCT06604468 | RECRUITING

30 participants

A Portable Thoracic Impedance Device for Detecting Pulmonary Congestion in Heart Failure Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2025-09-01
Completion:: 2026-06-30

Conditions

Heart Failure

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06596902 | RECRUITING | NA

290 participants

Promoting Physical Activity and Fitness Among Underserved Latino Families Living in U.S.-Mexico Border Regions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-06-24
Completion:: 2027-03-31

Conditions

Obesity Prevention
Heart Disease

Interventions

BEHAVIORAL

No Results Yet

NCT06590402 | RECRUITING | PHASE4

60 participants

Anterior Femoral and Adductor Canal Nerve Blocks in Peds Knees

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2025-06-06
Completion:: 2027-06-30

Conditions

Anterior Cruciate Ligament Reconstruction
Medial Patellofemoral Ligament Reconstruction

Interventions

DRUG

No Results Yet

NCT06529614 | RECRUITING

100 participants

An In-situ Detection for MicroRNA

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-07-20
Completion:: 2025-09-01

Conditions

Breast Cancer

Interventions

OTHER

No Results Yet

NCT06524128 | COMPLETED | NA

24 participants

Evaluation of Perceived Satisfaction With the Use of the Dreeft® Device in Real-life Situations

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-07-22
Completion:: 2025-05-15

Conditions

People With Motor Disabilities

Interventions

DEVICE

No Results Yet

NCT06497413 | COMPLETED | NA

24 participants

Brain Vascular and Neurocognitive Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-04-16
Completion:: 2025-08-31

Conditions

Cognitive Decline
Cognitive Dysfunction
Alzheimer Disease
Vascular Disease, Peripheral

Interventions

DEVICE

No Results Yet

NCT06479655 | RECRUITING | PHASE4

116 participants

Compare the Efficacy and Outcome Between Fentanyl and Morphine as Analgo-sedation in Mechanically Ventilated Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-07-15
Completion:: 2025-11-15

Conditions

Effect of Drug

Interventions

DRUG

No Results Yet

NCT06433349 | RECRUITING

240 participants

A Multi-center Investigation of Family Health.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-05-13
Completion:: 2026-05-31

Conditions

Breast Cancer
Prostate Cancer
Colorectal Cancer
Hematologic Neoplasms
Caregivers

Interventions

OTHER

No Results Yet

NCT06377384 | COMPLETED | PHASE1

2 participants

FLIGHT Study for Childhood Chronic Illness

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2022-04-20
Completion:: 2024-04-30

Conditions

Chronic Illnesses, Multiple

Interventions

OTHER

No Results Yet

NCT06353854 | RECRUITING

600 participants

Prospective National Cohort Evaluating Predictive Biomarkers of Resistance to Immunotherapy in Patients With MSI/dMMR Metastatic Colorectal Cancer (CORESIM)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-02-12
Completion:: 2029-02-12

Conditions

Colorectal Cancer Metastatic
Microsatellite Instability-High Colorectal Cancer

No Results Yet

NCT06352918 | COMPLETED | NA

32 participants

Peripheral Central Catheter (PICC) Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-05-01
Completion:: 2023-11-30

Conditions

NEWBORN
Pain, Acute

Interventions

OTHER

No Results Yet

NCT06352528 | COMPLETED | PHASE1

18 participants

A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-04-29
Completion:: 2025-09-16

Conditions

Hepatic Impairment
Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT06347744 | COMPLETED | NA

1646 participants

Radicle Rest 24: A Study of Health and Wellness Products on Sleep and Related Health Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-06-17
Completion:: 2025-06-16

Conditions

Sleep
Sleep Disturbance
Sleep Disorder

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06343298 | RECRUITING | PHASE2

120 participants

To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-11-17
Completion:: 2026-07-01

Conditions

Difficult to Control Hypertension

Interventions

DRUG
OTHER

No Results Yet

NCT06320015 | RECRUITING

400 participants

Emergency Medicine Peer Outreach Worker Engagement for Recovery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-07-01
Completion:: 2026-09-30

Conditions

Substance Use Disorders
Overdose
Opioid Use Disorder
Alcohol Use Disorder

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06267248 | ENROLLING_BY_INVITATION

10 participants

Spine Registration Using 3D-Scanning

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2026-11-30
Completion:: 2026-11-30

Conditions

Spine Surgery

Interventions

DEVICE

No Results Yet

NCT06262477 | COMPLETED | PHASE1

300 participants

A Study to Evaluate the Pharmacokinetics, Safety and Immunogenicity of BIIB800 Subcutaneously (SC) Compared to Actemra® in Healthy Male Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-01-02
Completion:: 2024-09-25

Conditions

Healthy Volunteer

Interventions

DRUG

Results Available

NCT06260059 | RECRUITING | PHASE4

40 participants

Efficacy Of Sodium Glucose Transporter Inhibitor (SGLT2I) In Adult Patients With Congenital Heart Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-09-17
Completion:: 2026-12-31

Conditions

Adult Congenital Heart Disease
Heart Failure

Interventions

DRUG

No Results Yet

NCT06260033 | RECRUITING | PHASE2

18 participants

Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-07-23
Completion:: 2026-10-29

Conditions

Anatomic Stage IV Breast Cancer AJCC v8
Estrogen Receptor-Positive Breast Carcinoma
Metastatic Breast Carcinoma

Interventions

PROCEDURE
DRUG
OTHER
RADIATION

No Results Yet

NCT06236919 | RECRUITING | NA

160 participants

E-Emotio Project A Gamified Preventive School-based Paradigm Using Virtual Reality Technologies for Improving Emotional Regulation in Children and Adolescents.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-02-01
Completion:: 2025-12-30

Conditions

Emotional Regulation
Virtual Reality
Anxiety
Depression
Executive Function

Interventions

BEHAVIORAL

No Results Yet

NCT06222606 | RECRUITING | NA

160 participants

Surgery for Thyroid Cancer With or Without Autofluorescence to Prevent Hypoparathyroidism

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-01-01
Completion:: 2027-01-31

Conditions

Thyroid Cancer

Interventions

PROCEDURE

No Results Yet

NCT06210672 | WITHDRAWN

0 participants

Natural History Study in Patients With LGMDR5/2c

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2025-01-10
Completion:: 2025-09-01

Conditions

Gamma-sarcoglycanopathy

No Results Yet

NCT06196684 | ACTIVE_NOT_RECRUITING

30 participants

Early Safety and Clinical Efficacy of Mitral Allograft in Tricuspid Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2021-09-29
Completion:: 2026-09-29

Conditions

Allografts
Tricuspid Valve Insufficiency

Interventions

PROCEDURE

No Results Yet

NCT06177977 | RECRUITING | NA

80 participants

SS-HH-OCT as a Novel Diagnostic Modality for Early-Onset Retinal Dystrophies (EORDs)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-03-01
Completion:: 2026-12-31

Conditions

Retinal Dystrophies

Interventions

DEVICE

No Results Yet

NCT06168305 | ENROLLING_BY_INVITATION

1000 participants

Safety and Effectiveness of GENOSS® DES in Patients With Multivessel Coronary Artery Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-06
Start Date:: 2023-11-15
Completion:: 2028-02-28

Conditions

Percutaneous Coronary Intervention
Multivessel Coronary Artery Disease

Interventions

DEVICE

No Results Yet

NCT06158022 | COMPLETED | NA

60 participants

ED90 of Norepinephrine and Phenylephrine Infusions in Preeclamptic Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2024-10-03
Completion:: 2025-05-20

Conditions

Adverse Effect

Interventions

DRUG

No Results Yet

NCT06140498 | COMPLETED | NA

93 participants

Effects of Self-Efficacy Ecological Momentary Intervention (EMA) App

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-06
Start Date:: 2021-11-01
Completion:: 2022-12-15

Conditions

Self Efficacy

Interventions

BEHAVIORAL

No Results Yet