Clinical Trials Updated in 2025

NCT07081555 | RECRUITING | PHASE1

21 participants

A First-in-Human Phase 1 Safety and Biodistribution of [177Lu]Lu-ABY-271 in Subjects With HER2-positive Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-10-06
Completion:: 2027-01-01

Conditions

Metastatic Breast Cancer
HER2 + Breast Cancer

Interventions

DRUG

No Results Yet

NCT07080632 | NOT_YET_RECRUITING | NA

300 participants

Efficacy and Safety of Calculus Bovis Sativus (CBS) for Intracerebral Hemorrhage(CBSinICH)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-10-01
Completion:: 2026-03-01

Conditions

Intracerebral Hemorrhage
Brain Hemorrhage

Interventions

DRUG

No Results Yet

NCT07072975 | NOT_YET_RECRUITING | NA

50 participants

CPOD Patient's Tolerance of Intermittent Exercise With Inter-exercise Recovery Under Normoxic Hypoxia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-10-31
Completion:: 2027-07-31

Conditions

Intermittent Hypoxia
Exercise Recovery
Intermittent Exercise
Rating Exertion Perception
Sleep

Interventions

OTHER

No Results Yet

NCT07065409 | RECRUITING | PHASE1

9 participants

Treatment of Moyamoya Disease With iPSC-derived Exosomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-05-26
Completion:: 2026-05-31

Conditions

Moyamoya Disease

Interventions

BIOLOGICAL

No Results Yet

NCT07062419 | COMPLETED | NA

58 participants

Effect of Sonic Activation of Irrigant on Post Operative Pain After Root Canal Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-01-01
Completion:: 2025-07-25

Conditions

Post Operative Pain
Root Canal Therapy

Interventions

DEVICE

No Results Yet

NCT07054242 | NOT_YET_RECRUITING | PHASE2

52 participants

A Prospective, Single-center, Phase II Study of Sacituzumab Tirumotecan in Combination With Pembrolizumab for Neoadjuvant Treatment of Triple-Negative Breast Cancer (TNBC)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-10-30
Completion:: 2026-10-30

Conditions

Neoadjuvant Therapy
Stage II to III (T1cN1-2 or T2-4N0-2) TNBC Breast Cancer

Interventions

DRUG

No Results Yet

NCT07049172 | COMPLETED | NA

91 participants

Rituximab and Targeted Nursing for Pediatric Nephrotic Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2021-01-01
Completion:: 2023-12-31

Conditions

Nephrotic Syndrome in Children

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT07045467 | RECRUITING | PHASE1

30 participants

Remimazolam Infusion in Kidney Transplant Patients: A Multicenter Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-07-01
Completion:: 2026-07-01

Conditions

Chronic Kidney Diseases
Renal Transplantation

Interventions

DRUG

No Results Yet

NCT07020676 | COMPLETED

108 participants

Dynamics of the Urinary Bacterial Microbiota

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-11-09
Completion:: 2025-03-07

Conditions

Urinary Infection

No Results Yet

NCT07011888 | NOT_YET_RECRUITING | NA

1 participants

Innovative Physiotherapy in Stroke Rehabilitation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-11-15
Completion:: 2025-12-30

Conditions

Stroke, Ischemic
Chronic Stroke Survivors

Interventions

DEVICE

No Results Yet

NCT07010484 | RECRUITING

149 participants

Using Novel Imaging to Rethink Diagnostic and Treatment Strategies for Polymyalgia Rheumatica

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-08-21
Completion:: 2028-08-31

Conditions

Polymyalgia Rheumatica (PMR)

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07010081 | RECRUITING | NA

220 participants

Using Digital Health in a Postoperative Setting After Major Surgery: Survey Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-05-26
Completion:: 2026-05-01

Conditions

Digital Health

Interventions

PROCEDURE

No Results Yet

NCT07005934 | ACTIVE_NOT_RECRUITING | NA

30 participants

Effects of Percussion Therapy on the Biomechanics of Pickleball Movement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-06-27
Completion:: 2025-12-31

Conditions

Injury;Sports
Muscle Soreness

Interventions

DEVICE

No Results Yet

NCT07000591 | COMPLETED | NA

96 participants

Massage Based on the Human Caring Model in Epilepsy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-06-15
Completion:: 2025-06-15

Conditions

Epilepsy

Interventions

OTHER

No Results Yet

NCT06994923 | RECRUITING | NA

60 participants

Weight Management Intervention in College: A Pilot

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-01-20
Completion:: 2027-03-01

Conditions

Obesity and Overweight

Interventions

BEHAVIORAL

No Results Yet

NCT06972355 | RECRUITING | NA

36 participants

Efficacy of Treadmill Walking With Hidden Vision for Rehabilitation in the Subacute Phase of Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-06-04
Completion:: 2027-06-04

Conditions

Subacute Stroke

Interventions

PROCEDURE

No Results Yet

NCT06955741 | COMPLETED | PHASE1

46 participants

A Study to Assess Drug Levels, Tolerability and Absolute Biological Availability of Single-dose of BMS-986446 in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-05-05
Completion:: 2025-09-11

Conditions

Healthy Volunteer

Interventions

DRUG

No Results Yet

NCT06940050 | RECRUITING | NA

34 participants

Comparing CAF and TCAF With Soft Tissue Grafting for Treating Multiple Recessions in the Premandibula.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-04-30
Completion:: 2036-12-31

Conditions

Gingival Recession, Localized
Gingival Recession, Plastic Surgery
Gingival Recessions
Gingival Recession, Mucogingival Surgery

Interventions

PROCEDURE

No Results Yet

NCT06933524 | NOT_YET_RECRUITING | PHASE1

24 participants

Evaluation of Safety and Tolerability of ATB-320 in Participants With Progressive or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-12-01
Completion:: 2028-12-01

Conditions

Solid Tumors

Interventions

DRUG

No Results Yet

NCT06929221 | NOT_YET_RECRUITING | NA

128 participants

The Effect of Bedside Whiteboard Use on Anxiety, Depression and Nursing Care in Chronic Obstructive Pulmonary Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-12-15
Completion:: 2026-04-15

Conditions

COPD
Nursing Care

Interventions

OTHER

No Results Yet

NCT06907914 | RECRUITING | NA

56 participants

Schroth and Scapular Muscle Activation in Hyperkyphosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-06-15
Completion:: 2026-05-01

Conditions

Hyperkyphosis, Adolescent
Muscle Activation
Scapula; Deformity, Acquired
Exercise Therapy

Interventions

OTHER

No Results Yet

NCT06907901 | RECRUITING

128 participants

Reliability of PHAS in Postural Hyperkyphosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-06-01
Completion:: 2026-05-01

Conditions

Postural Kyphosis
Spine
Assessment, Self

Interventions

BEHAVIORAL

No Results Yet

NCT06907719 | COMPLETED | NA

996 participants

Strong Fathers, Stronger Families Healthy Marriage and Responsible Fatherhood Program Evaluation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2021-04-01
Completion:: 2025-01-15

Conditions

Fathers

Interventions

OTHER

Results Available

NCT06899802 | ACTIVE_NOT_RECRUITING | PHASE2

411 participants

A Phase 2 Trial in Healthy Adult Participants of the Recombinant MVA-BN-WEV Vaccine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-03-10
Completion:: 2027-02-28

Conditions

Encephalitis

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT06893471 | ENROLLING_BY_INVITATION | NA

45 participants

From Yearly Checks to Daily Progress: Evaluating Goal Attainment Scaling (GAS) in Systematic Work Environment Management (SAM) Within the Municipal Sector

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2024-08-15
Completion:: 2027-12-31

Conditions

Behavior Change Interventions
Work Environment Adverse Effects
Health Factors
Goal Attainment Scaling

Interventions

OTHER

No Results Yet

NCT06892041 | RECRUITING

90 participants

Diffusion MRI for Quantitative Assessment of Myofascial Pain

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-09-04
Completion:: 2026-07-31

Conditions

Masticatory Myofascial Pain Syndrome

No Results Yet

NCT06889883 | RECRUITING

510 participants

Development and Validation of a Blood Test for Early Diagnosis of Colorectal Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-06-06
Completion:: 2025-12-31

Conditions

Colorectal Carcinoma
Advanced Adenomas (AA)

No Results Yet

NCT06889844 | RECRUITING

250 participants

Observational Cross-reactivity Study for Colorectal Cancer Diagnosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2023-04-17
Completion:: 2025-12-31

Conditions

Colorectal Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06887088 | RECRUITING | PHASE2

33 participants

Encorafenib and biNimetinib Followed by CEmiplimab and FiAnLimab in Patients With BRAF Mutant melanOma and Symptomatic Brain Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-05-29
Completion:: 2028-01-31

Conditions

Melanoma BRAF V600E/K Mutated
Melanoma and Brain Metastases

Interventions

DRUG

No Results Yet

NCT06876064 | NOT_YET_RECRUITING

150 participants

National Cohort of Subjects at Risk of Developing Rheumatoid Arthritis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-10-31
Completion:: 2027-12-31

Conditions

Rheumatoid Arthritis (RA)

Interventions

BIOLOGICAL
OTHER
RADIATION
DIAGNOSTIC_TEST

No Results Yet

NCT06865742 | NOT_YET_RECRUITING | NA

60 participants

Music Therapy Applied During Hemodialysis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-11-03
Completion:: 2025-12-05

Conditions

Hemodialysis

Interventions

BEHAVIORAL

No Results Yet

NCT06858865 | COMPLETED | PHASE1

60 participants

A Study to Evaluate the Safety and Pharmacokinetics of AD-228A Compared to Coadministration of AD-2281 and AD-2282

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-07-12
Completion:: 2025-08-14

Conditions

Primary Hypercholesterolaemia

Interventions

DRUG

No Results Yet

NCT06848842 | RECRUITING | PHASE2

40 participants

Ivonescimab Plus Chemotherapy in Patients With Initially Unresectable Colorectal Cancer Liver Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-09-18
Completion:: 2027-06-30

Conditions

Colorectal Liver Metastases

Interventions

DRUG

No Results Yet

NCT06839027 | NOT_YET_RECRUITING

130 participants

Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2026-05-02
Completion:: 2026-09-02

Conditions

Patient Undergoing CABG Surgery
Ischemic Heart Disease Patients

No Results Yet

NCT06824818 | RECRUITING | NA

155 participants

Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2026-06-30
Completion:: 2026-12-31

Conditions

Elderly
Prostate Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06797206 | RECRUITING

60 participants

A Study of Females With CF Throughout Pregnancy and Post-partum, and Follow up of Their Offspring

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-06-12
Completion:: 2028-04-30

Conditions

Cystic Fibrosis (CF)
Pregnancy
Infant, Newborn
Exposure During Pregnancy

No Results Yet

NCT06785948 | RECRUITING | NA

30 participants

tDCS Effect on Psychotic Symptoms in Dementia With Lewy Bodies (DLB), and Impacts on Caregiver Burden

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-01-10
Completion:: 2026-11-30

Conditions

Lewy Body Dementia
Lewy Body Dementia With Behavioral Disturbance
Burden, Caregiver
Lewy Body Disease
Dementia With Lewy Bodies

Interventions

DEVICE

No Results Yet

NCT06784011 | COMPLETED

19 participants

SHIFT-Hospital in Motion (Hospital Implementation Study)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2024-11-25
Completion:: 2025-03-11

Conditions

Hospitalized Patients
Physical Inactivity

No Results Yet

NCT06781762 | RECRUITING

40 participants

Short-term Impacts of Endocrine Therapy on Cardiovascular and Brain Health Outcomes in Breast Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-06-06
Completion:: 2026-12-30

Conditions

Breast Cancer Females

Interventions

OTHER

No Results Yet

NCT06779890 | RECRUITING | PHASE4

84 participants

Effect of Volatile- Based Versus Total Intravenous Anesthesia on Brain Homeostasis and Neurocognitive Outcome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-01
Start Date:: 2025-05-12
Completion:: 2026-09-30

Conditions

Brain Edema Caused by Drugs
Cerebral Oxygenation

Interventions

DRUG

No Results Yet